Clinical trials: Azithromycin
Childhood Mortality
Neonates and Azithromycin, an Innovation in the Treatment of Children in Burkina Faso
Although under-5 mortality rates are declining globally, neonatal mortality remains persistently high in many regions of sub-Saharan Africa.
- Trial name
- NAITRE (NCT03682653)
- Testing
- Azithromycin
- Where
- Burkina Faso
- Volunteers
- 21,832 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Assisted Reproductive Technology, Antibiotic Prophylaxis
Prophylactic Antibiotics Prior to Embryo Transfer (PAPET): RCT
The objective of this study is to determine the impact on clinical pregnancy rate of withholding routine prophylactic antibiotic therapy during IVF.
- Conditions
- Assisted Reproductive Technology, Antibiotic Prophylaxis, Embryo Transfer
- Trial name
- PAPET (NCT03386227)
- Testing
- Withholding antibiotic prophylaxis
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Infection
Timing of Antibiotic Prophylaxis for Cesarean Deliveries
The current standard of care to prevent post partum infectious morbidities is to administer antibiotic prophylaxis to all women undergoing a cesarean delivery.
- Trial name
- NCT00805545
- Testing
- Antibiotic
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Florida
HIV Infections, Cryptosporidiosis
Interleukin 12 (IL-12) for the Treatment of Cryptosporidiosis in AIDS Patients
There is no proven effective treatment for chronic diarrhea caused by the parasite Cryptosporidium in advanced AIDS. This trial will test the safety of interleukin-12 (IL-12) as part of a combination therapy for this parasite.
- Trial name
- NCT00057486
- Testing
- IL-12
- Volunteers
- 2 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cystic Fibrosis
OPTIMIZing Treatment for Early Pseudomonas Aeruginosa Infection in Cystic Fibrosis
The purpose of this trial is to compare the effects of treatment with tobramycin solution for inhalation (TIS) with and without azithromycin in people with cystic fibrosis (CF) age 6 months to 18 years who have early isolation of…
- Trial name
- OPTIMIZE (NCT02054156)
- Testing
- azithromycin, Tobramycin solution for inhalation
- Where
- 45 sites in United States
- Volunteers
- 221 people
- Sponsor
- Bonnie Ramsey
Uncomplicated Falciparum Malaria
Azithromycin Combination Therapy for the Treatment of Uncomplicated Falciparum Malaria in Bangladesh
The purpose of this study is to investigate the efficacy of azithromycin combination therapy with artesunate for the treatment of uncomplicated falciparum malaria in Bangladesh.
- Trial name
- NCT00356005
- Testing
- azithromycin plus artesunate, Artesunate
- Where
- Bangladesh
- Volunteers
- 228 people
- Sponsor
- Medical University of Vienna
Acne Vulgaris
Vitamin D Supplementation in Acne
The goal of this clinical trial is to compare in acne vulgaris patients. The main question it aims to answer is: To assess the therapeutic benefit of vitamin D supplement in acne vulgaris treatment, following a 2-month treatment…
- Trial name
- NCT06141330
- Testing
- D Max Drops, Azithromycin 250 milligram Oral Capsule, Adapalene
- Where
- Pakistan
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- HITEC-Institute of Medical Sciences
Chronic Obstructive Pulmonary Disease With Exacerbation
Comparative Effectiveness of Roflumilast and Azithromycin in Reducing Exacerbations in Severe Chronic Obstructive Pulmonary Disease ( COPD ) Patients With Chronic Bronchitis Phenotype
"The study is a randomized controlled trial comparing roflumilast and azithromycin as add-on therapies in 70 patients with severe chronic obstructive pulmonary disease (COPD ) and frequent exacerbations.
- Trial name
- COPD (NCT07795086)
- Testing
- Roflumilast Oral Tablet, Azithromycin 250 mg
- Volunteers
- 70 people
- Sponsor
- Sidra Aziz
COVID-19
Hydroxychloroquine and Azithromycin as Prophylaxis for Healthcare Workers Dealing With COVID19 Patients
The main objective of this study is to assess the efficacy of the combination hydroxychloroquine and Azithromycin (HCQ and AZ) in reducing the infection risk among health care professionals in direct contact with COVID-19…
- Trial name
- MOPHYDA (NCT04354597)
- Testing
- HCQ & AZ
- Where
- Jordan
- Volunteers
- healthy volunteers welcome
- Sponsor
- King Hussein Cancer Center
Malaria, Falciparum
Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine or Chloroquine/Azithromycin Prophylaxis
This study will assess the superior protective immunity of the combination of chloroquine and azithromycin prophylaxis under Chemoprophylaxis Sporozoites (CPS) immunization versus a standard chloroquine prophylactic regimen.
- Trial name
- MMV (NCT01783340)
- Testing
- Azithromycin capsules, Immunization with falciparum
- Where
- Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Chronic Periodontitis
Efficacy of Oral Probiotic and Antibiotic Administration in Patients With Chronic Periodontitis
The aim of this randomized placebo- controlled clinical trial is to evaluate the effects of Lactobacillus rhamnosus SP1- containing probiotic tablets and azithromycin tablets as an adjunct to scaling and root planning (SRP).
- Trial name
- NCT02839408
- Testing
- Lactobacillus rhamnosus SP1, Azithromycin, Talc powder
- Where
- Chile
- Volunteers
- 54 people
- Sponsor
- University of Chile
Cryptosporidiosis, HIV Infections
Azithromycin in the Treatment of Cryptosporidiosis in Patients With Acquired Immune Deficiency Syndrome (AIDS): A Randomized, Multi-Center, Placebo-Controlled, Double-Blind Study
To evaluate the safety and efficacy of azithromycin in the treatment of intestinal cryptosporidial infection in AIDS patients.
- Trial name
- NCT00002082
- Testing
- Azithromycin
- Where
- 4 sites in United States
- Sponsor
- Pfizer
Tuberculosis, Multidrug-Resistant
The Individualized M(X) Drug-resistant TB Treatment Strategy Study
This is a randomized controlled clinical trial comparing treatment success of a gene-derived individualized drug-resistant Tuberculosis regimen to a standard Tuberculosis regimen based on South African National Tuberculosis…
- Trial name
- InDEX (NCT03237182)
- Testing
- Individualized TB treatment with multiple drugs, Standardized TB treatment with multiple drugs
- Where
- South Africa
- Volunteers
- 205 people
- Sponsor
- Centre for the AIDS Programme of Research in South Africa
Mycobacterium Avium-intracellulare Infection, HIV Infections
The Safety and Effectiveness of Rifabutin, Combined With Clarithromycin or Azithromycin, in HIV-Infected Patients
PER 03/10/94 AMENDMENT: PART B. To determine whether there is an effect on plasma drug levels of azithromycin and rifabutin as measured by changes in the plasma concentration-time curve (AUC) when these drugs are taken…
- Trial name
- NCT00001023
- Testing
- Clarithromycin, Azithromycin, Rifabutin
- Where
- 11 sites in United States
- Volunteers
- 91 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Coronavirus Infections
Safety and Efficacy of Hydroxychloroquine Associated With Azithromycin in SARS-Cov-2 Virus (COVID-19)
Coronavirus (COVID-19) is a somewhat new and recognized infectious disease that is now spreading to several countries in the world, including Brazil. Hydroxychloroquine and azithromycin may be useful for treating those patients.
- Trial name
- Coalition-I (NCT04322123)
- Testing
- Hydroxychloroquine Oral Product, Hydroxychloroquine + azithromycin
- Where
- 28 sites in Brazil
- Volunteers
- 667 people
- Sponsor
- Hospital do Coracao
Upper Respiratory Tract Infections
Trulimax (Azithromycin ) Non-Interventional Study In Acute Bacterial Upper Respiratory Tract Infections
To assess effectiveness of Trulimax (Azithromycin) in Acute Bacterial Upper Respiratory Tract Infections (URTIs).
- Trial name
- NCT00827502
- Where
- 11 sites in India
- Volunteers
- 421 people
- Sponsor
- Pfizer
Bronchiectasis
Macrolides in COPD- Bronchiectasis Overlap
To assess safety of long-term macrolide therapy in patients with COPD-bronchiectasis overlap syndrome And evaluate its efficacy in treating COPD-bronchiectasis overlap syndrome regarding change in clinical, functional and…
- Trial name
- NCT04215172
- Testing
- Macrolides
- Volunteers
- 60 people
- Sponsor
- Assiut University
Periodontal Disease, Chronic Periodontitis
Evaluation of Techniques for Scaling and Root Planing and One Stage Full Mouth Disinfection
Evaluate and compare the effectiveness in a clinical and microbial perspective one stage full-mouth disinfection technique in relation to scaling and root planing per quadrant associated with chlorhexidine or azithromycin.
- Trial name
- NCT02126267
- Testing
- Scaling and root planing, Full mouth disinfection, Chlorhexidine gel and gluconate
- Where
- Brazil
- Volunteers
- 77 people
- Sponsor
- Centro Universitario de Lavras
Trachoma
Nepal Elimination of Trachoma Study
The main purpose of this study is to determine if ocular Chlamydia trachomatis infection can be eliminated in communities in Nepal following mass antibiotic distributions with azithromycin.
- Trial name
- NETS (NCT02176057)
- Testing
- Azithromycin
- Where
- Nepal
- Sponsor
- University of California, San Francisco
Malnutrition, Child, Severe Acute Malnutrition
Azithromycin as Adjunctive Treatment for Uncomplicated Severe Acute Malnutrition
Amoxicillin is recommended by the World Health Organization (WHO) as adjunctive therapy for the treatment of uncomplicated severe acute malnutrition (SAM).
- Trial name
- AMOUR (NCT06010719)
- Testing
- Azithromycin, Amoxicillin
- Where
- Burkina Faso
- Volunteers
- 3,000 people
- Sponsor
- University of California, San Francisco