Clinical trials: completed, sponsored by M.D. Anderson Cancer Center
Spinal Cord
Establishing Daily Applicable Parameters for Using Magnetic Resonance Spectroscopy of Spinal Cord
To learn if MRS can effectively assess spinal cord lesions.
- Trial name
- NCT06548776
- Testing
- Magnetic Resonance Spectroscopy (MRS) Scan
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cigarette Smoker, Tobacco Use Disorder
Varenicline and Combined NRT for Smoking Cessation
This randomized pilot phase IV trial studies the side effects and how well varenicline works compared to nicotine replacement therapy in helping patients that smoke to quit.
- Trial name
- NCT02271919
- Testing
- Nicotine Lozenge, Nicotine Patch, Tobacco Cessation Counseling
- Where
- United States
- Volunteers
- 631 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8
Pembrolizumab in Preventing Lung Cancer in Patients With Stage I-II Non-Small Cell Lung Cancer or High-Risk Pulmonary Nodules, the IMPRINT-Lung Study
This phase II trial studies how well pembrolizumab works in preventing lung cancer patients with stage I-II non-small cell lung cancer or high-risk pulmonary nodules.
- Conditions
- Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8, Stage IA2 Lung Cancer AJCC v8
- Trial name
- NCT03634241
- Testing
- Pembrolizumab, Quality-of-Life Assessment, Computed Tomography
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cigarette Smoking-Related Carcinoma
Gender Differences in Switching From Smoking Regular Cigarettes to E-Cigarettes
This early phase I trial studies potential differences between men and women when switching from the use of combustible cigarettes to the National Institute on Drug Abuse's Standard Research E-Cigarette (SREC).
- Trial name
- NCT03856515
- Testing
- Nicotine Replacement, Questionnaire Administration, Electronic Cigarette
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cigarette Smoking-Related Carcinoma, Tobacco-Related Carcinoma
Very Low Nicotine Content Cigarettes and E-Cigarettes in Promoting Smoking Cessation in Daily and Intermittent Cigarette Smokers
This trial studies what would happen if the nicotine levels in cigarettes are greatly reduced, but electronic cigarettes containing different amount of nicotine are available.
- Trial name
- NCT02964182
- Testing
- Cigarette, Nicotine Replacement, Questionnaire Administration
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer Screening
The Effect of the Prostate Cancer Foundation Screening Guidelines for Black Men on Intention to Screen in Faith-based Communities
To learn about barriers to prostate cancer screening in Black, faith-based communities. Investigators will use the information collected in this study to create a prostate cancer education program that is relevant to Black men…
- Trial name
- NCT06838325
- Testing
- Prostate Cancer Screening
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Positive Activities Intervention to Improve Quality of Life in Collectivist Culture Cancer Patients and Their Caregivers
This clinical trial studies the feasibility of two positive activities in improving quality of life in collectivist culture cancer patients and their caregivers.
- Trial name
- NCT04810052
- Testing
- Behavioral Intervention, Interview, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Healthy Subject
Project Self in Improving Cervical Cancer Screening Rates in Hispanic and African American Women
This trial studies if Project Self can improve the rate of cervical cancer screening in Hispanic and African American women living in Houston, Texas.
- Trial name
- NCT04614155
- Testing
- Educational Intervention, HPV Self-Collection, Questionnaire Administration
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Gynecology
An Endometrial Cancer Chemoprevention Study of Metformin
The goal of this clinical research study is to learn about the effects of metformin and/or a program called "lifestyle intervention" on the endometrium (inner lining of the uterus) in post-menopausal women who are also obese…
- Trial name
- NCT01697566
- Testing
- Metformin, Endometrial Biopsy, Lifestyle Intervention
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Smoking Cessation
Combining Varenicline and Bupropion for Smoking Cessation
The goal of this clinical research study is learn if the combination of Chantix (varenicline) and Zyban (bupropion) is more effective at helping people to quit smoking than varenicline when given alone.
- Trial name
- NCT00943618
- Testing
- Varenicline, Bupropion, Counseling/Phone Calls
- Where
- United States
- Volunteers
- 641 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Caregiver, Malignant Female Reproductive System Neoplasm
Impact of a Systematic Social Work Driven Approach on Medical Power of Attorney Documentation, Knowledge, Attitudes, and Beliefs in Participants With Stage I-IV Gynecological Cancers
This trial evaluates the impact of a systemic social work driven approach on medical power of attorney documentation, knowledge, attitudes, and beliefs in participants with stage I-IV gynecological cancers.
- Trial name
- NCT03037346
- Testing
- Questionnaire Administration, Video
- Where
- United States
- Volunteers
- 731 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Hematopoietic Cell Transplantation Recipient, Refractory B-Cell Non-Hodgkin Lymphoma
Gemcitabine Hydrochloride, Clofarabine, and Busulfan Before Donor Stem Cell Transplant in Treating Patients With Refractory B-Cell or T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma
This phase I/II trial studies the side effects and best dose of gemcitabine hydrochloride, clofarabine, and busulfan before donor stem cell transplant and to see how well it works in treating patients with B-cell or T-cell…
- Conditions
- Hematopoietic Cell Transplantation Recipient, Refractory B-Cell Non-Hodgkin Lymphoma, Refractory Hodgkin Lymphoma, Refractory T-Cell Non-Hodgkin Lymphoma
- Trial name
- NCT01701986
- Testing
- Allogeneic Bone Marrow Transplantation, Allogeneic Hematopoietic Stem Cell Transplantation, Anti-Thymocyte Globulin
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Pain Syndrome, Pain
A Pilot Study Assessing the Effectiveness of Use of Guided Imagery for Treatment of Pain and Symptom Management in Women With Post-mastectomy Pain Syndrome
To learn if using guided imagery and deep breathing techniques can help with pain management in patients who have post-mastectomy pain syndrome.
- Conditions
- Pain Syndrome, Pain, Symptom Management
- Trial name
- NCT05408741
- Testing
- The Intervention Group, The Control Group
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Lung Disorder
Ventilatory Strategy for the Prevention of Atelectasis During Bronchoscopy Under General Anesthesia, VESPA Trial
This trial compares two different types of ventilation for the prevention of partial or complete collapsed lung (atelectasis) in patients undergoing bronchoscopy under general anesthesia.
- Trial name
- NCT04311723
- Testing
- Anesthesia Procedure, Bronchoscopy
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Breast Carcinoma, Deleterious CDH1 Gene Mutation
Factors Influencing Cascade Testing Among Women With Hereditary Gynecological Cancers and Their Relatives
This trial collects information about factors that affect communication of genetic test results, decision-making, and access to genetic testing in women with hereditary gynecological cancers.
- Conditions
- Breast Carcinoma, Deleterious CDH1 Gene Mutation, Deleterious DICER1 Gene Mutation, Deleterious SMARCA4 Gene Mutation
- Trial name
- NCT04257045
- Testing
- Interview, Questionnaire Administration, Survey Administration
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Head and Neck Cancer
Exploring the Neuro-Immune Basis of Cancer-Related Fatigue Using Behavioral Measures
The goal of this research study is to learn more about fatigue and how it affects your behavior as well as your willingness to learn new behaviors.
- Trial name
- NCT02255773
- Testing
- Computerized Tasks, Questionnaires
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Advanced Cancer, Dehydration
Parenteral Hydration in Advanced Cancer Patients
The goal of this clinical research study is to learn whether being hydrated (given liquids) through a catheter in a vein or in the tissue under the skin can improve symptoms of dehydration.
- Trial name
- NCT00423722
- Testing
- Saline
- Where
- 5 sites in United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Mammographically Dense Breast
Afimoxifene in Reducing the Risk of Breast Cancer in Women With Mammographically Dense Breast
This randomized phase II trial studies how well afimoxifene works in reducing the risk of breast cancer in women with mammographically dense breast. Estrogen can cause the growth of breast cancer cells.
- Trial name
- NCT03063619
- Testing
- Afimoxifene, Laboratory Biomarker Analysis, Questionnaire Administration
- Where
- 5 sites in United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Caregiver, Malignant Neoplasm
A Survey of Parent/Caregiver Practices on the Storage, Use, and Disposal of Opioids in a Comprehensive Cancer Center
This trial uses a survey to study parent and caregiver practices on the storage, use, and disposal of opioids in a comprehensive cancer center.
- Trial name
- NCT03390283
- Testing
- Survey Administration
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Cancer
Using Multimedia Approaches to Communicate Probabilities in Patient Decision Aids for Low-Literacy Populations: Randomized Trial
The goal of this research study is to compare how people who are 45-75 years old respond to 3 different versions of a program about screening tests for colorectal cancer.
- Trial name
- NCT02151032
- Testing
- Booklet, Audio CD, Video with Non-Moving Images
- Where
- 4 sites in United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center