Clinical trials: Insulin
Healthy Young Adults
Effects of Exogenous Ketones in Healthy Young Adults
Exogenous ketone supplements in the form of beta-hydroxybutyrate can be utilized as an alternate energy source (in place of glucose) for all cells except red blood cells.
- Trial name
- NCT03452761
- Testing
- Ketone Salts
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Augusta University
Obesity
Muscle Lipid and Insulin Resistance in the Elderly
This project will provide novel information concerning the ability of exercise to enhance the capacity for oxidative metabolism of fatty acids and improve insulin resistance in older adults who are at high risk for the…
- Trial name
- MIRA (NCT00765505)
- Testing
- Exercise Group, Health Education Group
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Arterial Occlusive Disease, Intermittent Claudication
ARREST PAD (Peripheral Arterial Disease)
This trial will test the hypothesis that inflammation and insulin resistance contribute to reduced walking distance in subjects with intermittent claudication by impairing vascular reactivity and skeletal muscle metabolic…
- Conditions
- Arterial Occlusive Disease, Intermittent Claudication, Insulin Resistance
- Trial name
- NCT00153166
- Testing
- atorvastatin and pioglitazone
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea, Diabetes Mellitus
Assessing the Risk of Developing Type II Diabetes Using Serum Biomarkers in Patients Diagnosed With Obstructive Sleep Apnea
The investigators plan to recruit 140 patients (35 subjects in each group) over a period of 18 months in a prospective study of matched/paired case-control subjects across the four groups to measure the 5-year risk of developing…
- Trial name
- OSA & DM (NCT01447251)
- Testing
- PreDx Diabetes Risk Score
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mike O'Callaghan Military Hospital
Pre Diabetes
Abscisic Acid Effects on Glucose Homeostasis and Insulin Sensitivity
The purpose of this study is to determine the effects of oral abscisic acid (ABA) on glucose metabolism in subjects with defined prediabetes.
- Trial name
- ABA (NCT04722354)
- Testing
- Hyperinsulemic euglycemic clamp, Muscle Biopsy, Oral abscisic acid (ABA)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Type 1 Diabetes Mellitus
The Effect of Diabetes Education Digital Games and Video Animation on Quality of Life
This research will be conducted to evaluate the effect of digital game and video animation-based diabetes education on the quality of life of children with Type 1 Diabetes.
- Trial name
- NCT05649553
- Testing
- digital game and video animation based diabetes education
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Diabetes (DM)
Studies of Insulin and Glucagon Action in the Liver
This study examines how glucagon works to regulate glucose metabolism, based on new findings that suggest glucagon signaling in the liver has more than one role, and that these multiple roles can be opposing in nature.
- Trial name
- SIGNAL (NCT07300982)
- Testing
- Glucagon
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Glycemic Response, Insulinemic Response
Glycemic Index of Traditional Egg Pasta
The glycemic index (GI) compares the plasma glucose response to a specific amount of carbohydrates with the response induced by the same amount of carbohydrates from a standard carbohydrate source, pure glucose in our case.
- Conditions
- Glycemic Response, Insulinemic Response, Healthy Subjects
- Trial name
- NCT03298529
- Testing
- glucose solution, Traditional egg pasta, Pasta with eight egg whites/kg flour
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
To Investigate the Physiological Effect of GLP-1 on the Skeleton, Healthy Volunteer
SHORT-term Effects of GLucagon-like Peptide One on BonE
Bone is a dynamic organ that is remodelled throughout life by a coupled process of resorption and formation of bone tissue, which are highly energy-demanding processes.
- Trial name
- SHORT-GLOBE (NCT06722560)
- Testing
- GLP-1 hormone
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Sleep, Insomnia
Treatment of Insomnia and Glucose Metabolism
Available data suggest that obtaining adequate sleep is associated with a better ability of the body to use carbohydrates as a source of energy and a lower risk of developing diabetes.
- Conditions
- Sleep, Insomnia, Insulin Resistance
- Trial name
- NCT00724282
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Thin Gingival Biotype
Efficacy of Microneedling With Hyaluronic Acid Injection for Gingival Augmentation in Thin Gingival Phenotype
This randomized controlled trial adheres to the Consolidated Standards of Reporting Trials (CONSORT) 2010 guidelines and the Declaration of Helsinki ethical principles for medical research.
- Trial name
- NCT07317856
- Testing
- Microneedling (MN), Microneedling + Injectable Hyaluronic Acid (MN + HA)
- Where
- Iraq
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Healthy Volunteers, Diabetes Mellitus, Type 1
Evaluation of 18 F-FP-DTBZ Pancreatic PET Scanning as a Tool to Measure Beta Cell Mass
Type 1 diabetes mellitus (T1DM) develops when there is impaired insulin production due to loss of insulin producing cells (beta cells).
- Trial name
- NCT02236754
- Testing
- 18 F-FP-DTBZ, PET Scanning
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Columbia University
Obesity and Overweight, Pre-diabetic
Targeted Precision Nutrition Strategy To Prevent Chronic Metabolic Diseases
Nutrition is very important to keep blood sugar levels balanced. If blood sugar levels are too high, it can lead to diseases such as cardiovascular disease and type 2 diabetes (T2DM).
- Conditions
- Obesity and Overweight, Pre-diabetic, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- PRECINUT (NCT06923644)
- Testing
- Optimal Metabotype-specific diet, Sub-optimal diet
- Where
- 2 sites in Netherlands
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Fetal Growth Restriction, Gut Microbiota
Gut Microbiota, SCFAs and Glucolipid Metabolism in Pregnant Women With Abnormal Fetal Size and Their Newborns
Abnormal fetal size includes fetal growth restriction and fetal macrosomia. Onset is closely related to maternal nutrition metabolism.
- Conditions
- Fetal Growth Restriction, Gut Microbiota, Fetal Macrosomia, Glucolipid Metabolism
- Trial name
- NCT04399434
- Testing
- test gut microbiota, SCFAs and glucolipid metabolism and insulin sensitivity
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Healthy
A Study of LY900014 Formulation in Healthy Participants
This study evaluates a new formulation of LY900014, a drug that lowers blood sugar. It is administered by injection under the skin of the abdomen.
- Trial name
- NCT02942654
- Testing
- LY900014, Insulin Lispro
- Where
- Singapore
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Diabetes, Gestational Diabetes
Safety and Efficacy of Insulin Aspart vs. Regular Human Insulin in Gestational Diabetes
This trial is conducted in the United States of America (USA). The purpose of this study is to test whether NovoLog (insulin aspart) is a safe and at least as effective alternative to regular human insulin for the control of…
- Trial name
- NCT00065130
- Testing
- human insulin, insulin NPH, insulin aspart
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Calamansi Powder Capsule Supplementation
Effects of Calamansi on Blood Glucose and Insulin Levels
Fifty-four healthy sedentary male and female participants aged 18-30 years will be recruited for this study. Participants will be randomly assigned to one of two groups: a control group receiving placebo MMC capsules (n = 27) or…
- Trial name
- NCT07587905
- Testing
- MMC powder capsule, Calamansi powder capsule
- Where
- Thailand
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Burapha University
PreDiabetes, Obesity, Childhood
Conventional and Metabolomic Predictors of Prediabetes & Insulin Resistance
The purpose of this study is to evaluate the longitudinal test performance of an array of conventional biomarkers of glycemia, including Hemoglobin A1c (HbA1c), and novel metabolomic biomarkers for identifying progression of…
- Trial name
- NCT05055219
- Where
- United States
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obesity
Egg Diet to Improve Metabolic Health and Function
The purpose of this study is to determine the effects of change in diet quality (carbohydrate restriction versus fat restriction) on body composition, fat distribution, cardiometabolic risk factors, physical function, and quality…
- Trial name
- NCT02760641
- Testing
- Egg-based diet (EBD), Carbohydrate-based diet (CBD)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity
The Effects of Oral Glucose Compared to Sweetener Drinking on Hormonal/Metabolic Responses
The goal of this study is to determine the hormonal/metabolic reponse to ingestion of sugar compared to consuming artificial sweetened drink, and to evalute macronutrient consumption 24 hours post ingestion of the drinks.
- Trial name
- NCT01683929
- Testing
- glucose, sweetner
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.