Clinical trials: Azithromycin
Infections
Comparative Bioavailability Study of Azithromycin 200mg/5mL Suspension Following a 600mg Dose Under Fed Conditions
The purpose of this study is to demonstrate the bioequivalence of Azithromycin 200mg/5mL oral suspension.
- Trial name
- NCT00875966
- Testing
- Azithromycin for Oral Suspension 200mg/5mL Eon Pharma, LLC, Zithromax (azithromycin for oral suspension) 200mg/5mL Pfizer
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sandoz
Pregnancy Preterm, Pregnancy Prom
Outpatient Antibiotics Following Previable Rupture of Membranes (pPPROM) Between 18 0/7 and 22 6/7 Weeks Gestational Age
A randomized, controlled, non-placebo trial to primarily assess the effect of oral, outpatient antibiotics (i.e., azithromycin and amoxicillin) on latency (i.e., proportion of patients that deliver within 28 days from membrane…
- Conditions
- Pregnancy Preterm, Pregnancy Prom, PROM, Preterm (Pregnancy), PROM (Pregnancy)
- Trial name
- NCT05345457
- Testing
- Azithromycin Pill, Amoxicillin Pill
- Where
- 3 sites in United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Periodontitis
Effects of Azithromycin as an Adjunct to Scaling and Root Planning in the Treatment of Periodontitis
The growing interest in the possibilities of modulating macrophages in inflammatory diseases with therapeutic purpose has prompted the development of new approaches for the treatment of periodontitis.
- Trial name
- NCT05506371
- Testing
- Az+SRP, SRP, No interventions
- Where
- Ukraine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ukrainian Medical Stomatological Academy
Stillbirths and Infant Mortality
Oral Azithromycin to Prevent Stillbirths and Infant Mortality in Mali
The double blind randomized controlled trial will assess the efficacy of oral azithromycin administered to pregnant women and/or infants during routine care in preventing stillbirths and mortality through 6-12 months of age in…
- Trial name
- SANTE (NCT03909737)
- Testing
- Azithromycin to pregnant women, Azithromycin to infants, No intervention to pregnant women
- Where
- Mali
- Volunteers
- 99,700 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Healthy
Comparative Effects of Azithromycin, Telithromycin and Levofloxacin on Drug Metabolizing Enzymes
Studies have previously shown that a broad drug interaction screening can be performed using enzyme specific probes such as oral caffeine for CYP1A2, N-acetyltrasferase-2 (NAT-2), and xanthine oxidase (XO), warfarin plus vitamin…
- Trial name
- NCT00164112
- Testing
- Cooperstown 5+1 alone, Azithromycin plus Cooperstown 5+1, Telithromycin plus Cooperstown 5+1
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bassett Healthcare
Infection
Timing of Antibiotic Prophylaxis for Cesarean Deliveries
The current standard of care to prevent post partum infectious morbidities is to administer antibiotic prophylaxis to all women undergoing a cesarean delivery.
- Trial name
- NCT00805545
- Testing
- Antibiotic
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Florida
Trachoma
Sanitation, Water, and Instruction in Face-washing for Trachoma I/II
SWIFT I is a series of 3 cluster-randomized trials designed to assess several alternative strategies for trachoma control in communities that have been treated with many years of mass azithromycin distributions.
- Trial name
- SWIFT I/II (NCT02754583)
- Testing
- Water, sanitation, and hygiene (WASH) intervention, Standard of care WASH intervention, Azithromycin
- Where
- Ethiopia
- Volunteers
- 47,605 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
SARS-CoV-2 Infection
Prevention of SARS-CoV-2 in Hospital Workers s Exposed to the Virus
The Investigators propose to set up a preventive trial of infection in hospital workers at risk of coronavirus infection by comparing the rate of SARS-Cov-2 infection in a population of negative SARS-Cov-2 hospital workers…
- Trial name
- PREP-COVID (NCT04344379)
- Testing
- hydroxychloroquine, azithromycin
- Where
- 8 sites in France
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Covid19
Convalescent Plasma Treatment in COVID-19
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred initially in December 2019 in the city of Wuhan, Hubei province, China.
- Trial name
- COLLATE (NCT04476888)
- Testing
- Convalescent Plasma (CP), Drugs and supportive care
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Bacterial Vaginosis
Treatment of Bacterial Vaginosis
We are trying to determine if longer duration of therapy with metronidazole or combination therapy of metronidazole plus azithromycin results in better cure rates for BV
- Trial name
- NCT00324818
- Testing
- metronidazole and azithromycin
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Undernutrition
Nutritional Support for Lactating Women and Azithromycin to Infants - Mumta Lactating Women Trial
A community-based, randomized control, assessor blinded trial in peri-urban settings of Karachi, Pakistan to study the impact of Lipid-based Nutritional Supplement for Pregnant and Lactating women which is balanced energy-protein…
- Trial name
- MumtaLW (NCT03564652)
- Testing
- Balanced energy-protein (BEP), Azithromycin
- Where
- Pakistan
- Volunteers
- 957 people, healthy volunteers welcome
- Sponsor
- Vital Pakistan Trust
Neonatal SEPSIS
Pre-delivery Administration of Azithromycin to Prevent Neonatal Sepsis & Death
Though maternal and neonatal health are high priority areas for international development, maternal and neonatal mortality remain unacceptably high.
- Trial name
- PregnAnZI-2 (NCT03199547)
- Testing
- Azithromycin
- Where
- 2 sites in Burkina Faso, The Gambia
- Volunteers
- 11,985 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Cystic Fibrosis
Improving Treatment of Nontuberculous Mycobacterial Infection in Cystic Fibrosis
The purpose of this study is to determine antimycobacterial drug pharmacokinetics (PK) and pharmacodynamics (PD) in patients with cystic fibrosis (CF) to improve treatment of nontuberculous mycobacterial (NTM) lung disease.
- Trial name
- NCT02372383
- Testing
- Ethambutol, Rifampin, Azithromycin
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Eye Infections, Bacterial
Study of the Ocular Safety After Repeated Instillations of T1225 1% or 1.5% Eye Drops in Healthy Volunteers
To evaluate the ocular tolerance of T1225 1% and 1.5% eye drops versus vehicle after one instillation twice-daily (morning and evening), in one eye, during 3 days (from Day 0 to Day 2).
- Trial name
- NCT00357383
- Testing
- Azithromycin (T1225)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Laboratoires Thea
Pregnancy
Pharmacokinetics and Pharmacodynamics and Selected Antibiotics During Pregnancy
This protocol is a prospective, open-label, multicenter, population pharmacokinetic and pharmacodynamic study of selected anti-infective agents in pregnant women being treated for suspected or documented infections.
- Trial name
- NCT00214331
- Testing
- ciprofloxacin, azithromycin, gentamicin
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Trachoma, Lymphatic Filariasis
Safety Study of Combined Azithromycin, Ivermectin and Albendazole for Trachoma and Lymphatic Filariasis
Trachoma and lymphatic filariasis (LF) are two 'Neglected Tropical Diseases' (NTDs), infectious diseases that affect millions of poor people in countries in the developing world.
- Trial name
- AZIVAL2 (NCT01903057)
- Testing
- azithromycin, ivermectin, albendazole
- Where
- Mozambique
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emory University
Comparative Bioavailability Study
Influence of Ethnicity and ABCB1 Gene Polymorphism on the Pharmacokinetics of Azithromycin in Healthy Bangladeshi Volunteers
It is well recognized that different patients respond in different ways to the same medication. These differences are often greater among members of a population than they are within the same person at different times (or between…
- Trial name
- NCT05437783
- Testing
- Azithromycin Dihydrate
- Where
- Bangladesh
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh