Clinical trials: Amoxicillin, open to volunteers
Bone Regeneration, Safety Issues
Evaluation of Performance, Safety and Benefit of the Wishbone HA as Bone Graft Substitute, a Pre-market Clinical Investigation
This investigation is a pre-market, prospective, multi-center, randomized, single blinded, parallel controlled clinical investigation performed in at least 5 clinical centers for confirmatory purposes of the use of WHA as…
- Trial name
- NCT06383377
- Testing
- Tooth extraction and bone graft procedure
- Where
- 5 sites in Belgium
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Wishbone SA
Microbial Colonization, Antibiotic Side Effect
Autoflor -Lyophilized Capsulated Autological FMT to Restore Gut Microbiome After Treatment With Antibiotics
In this clinical trial, our aim is to assess the effect of auto-FMT (Fecal microbiome transplantation) on the intestinal microbiota, after a course of antibiotics. 30 healthy adults are recruited.
- Trial name
- FMT (NCT06250413)
- Testing
- FMT, Amox Clav
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Otto Helve
Obesity, Weight Loss
The Role of Microbiome in Recurrent Obesity Before and After Antibiotic/Placebo Treatment
This past century witnessed a significant increase in the prevalence of obesity. Successful weight loss maintenance is defined as losing at least 10% of the initial body weight and maintaining it for at least one year.
- Trial name
- NCT06681246
- Testing
- Antibiotic treatment
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Weizmann Institute of Science
Breastfeeding, COVID-19 Infection
Researchers At UC San Diego Are Learning About the Benefits of Human Milk and How It Influences Infant and Child Health
The purpose of the UCSD Human Milk Biorepository is to establish and maintain a repository of breast milk samples that can be used to learn more about how breast milk influences infant and child health.
- Conditions
- Breastfeeding, COVID-19 Infection, COVID-19 Vaccine, Remdesivir
- Trial name
- NCT05553743
- Testing
- COVID-19 Exposure, Antibiotic
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
HELICOBACTER PYLORI INFECTIONS, Helicobacter Infection
Vonoprazan vs Proton Pump Inhibitor With Vitamin D or Probiotics Based Triple Therapy for Eradication of Helicobacter Pylori Infection
Helicobacter pylori is a Gram-negative, spiral-shaped bacterium that infects up to 50% of the world's population, residing in the gastric mucosa and using the mucus layer for protection from the stomach's high acidity.
- Conditions
- HELICOBACTER PYLORI INFECTIONS, Helicobacter Infection, Helicobacter Pylori Gastrointestinal Tract Infection, Helicobacter Pylori Infected Patients
- Trial name
- NCT07293910
- Testing
- Vonoparazan, Vitamin D, Probiotic
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Tanta University
Oral Health Care
The Effect of Supplementary Foods Containing Trypsin, Chymotrypsin and Serratia Peptidase on Healing After Impacted Wisdom Tooth Surgery
Introduction: The aim of this study was to determine the effects of a dietary supplement containing trypsin, chymotrypsin, and serratia peptidase (Tripser Forte N30, Incir Pharma, Turkey) on postoperative healing and to determine…
- Trial name
- Trypsin (NCT07269171)
- Testing
- Pain Assessment, Number of Analgesics Needed, Edema Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar
Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery
This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing…
- Conditions
- Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar, Impacted Wisdom Tooth
- Trial name
- NCT07742826
- Testing
- Platelet-rich fibrin (PRF), Dexamethasone, Amoxicillin/Clavulanic Acid
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Final International University
Helicobacter Pylori Eradication Rate
Optimization of Keverprazan-amoxicillin Dual Therapy for Eradicating Helicobacter Pylori Infection
Eradication of HP can significantly improve and reduce HP-related diseases. A 10-14 day quadruple regimen containing bismuth as first-line treatment, achieving an eradication rate of more than 85%.
- Trial name
- NCT06734260
- Testing
- Keverprazan Hydrochloride tablets + high dose amoxicillin, Keverprazan Hydrochloride tablets + low dose amoxicillin, Keverprazan Hydrochloride tablets + high dose amoxicillin（H-KA-10d）
- Where
- 4 sites in China
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- Eighth Affiliated Hospital, Sun Yat-sen University
Helicobacter Pylori Infection
A "Screen and Treat" Helicobacter Pylori Eradication Trial in Adolescents in Three Regions of Chile
Gastric cancer remains a global health problem, and Chile has one of the highest GC mortality rates in the region. Helicobacter pylori (H.
- Trial name
- NCT05926804
- Testing
- Lansoprazole, Amoxicillin, Clarithromycin
- Where
- 3 sites in Chile
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Miguel O'Ryan Gallardo
Amoxicillin Allergy
Diagnosing Drug Allergy: the T is the Key
The goal of this clinical trial is to validate a newly developed test in the diagnosis of patients with amoxicillin allergy (i.e. T-cell activation test).
- Trial name
- TAT (NCT06409884)
- Testing
- T-cell activation test using intracellular markers
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Protracted Bacterial Bronchitis
Antibiotics, Microbiology and Immunology in Children With Chronic Wet Cough - the AMIC Study
The AMIC study is a double-blind, placebo-controlled, multicenter, nationwide, randomized controlled academic pharmaceutical trial.
- Trial name
- AMIC (NCT06020716)
- Testing
- Amoxicillin-Clavulanate 400 Mg-57 Mg/5 mL Oral Powder for Reconstitution
- Where
- 7 sites in Norway
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Erythema Migrans
Different Amoxicillin Treatment Regimens in Erythema Migrans Patients
The purpose of this study is to compare the efficacy of different amoxicilline treatment regimens in patients with erythema migrans.
- Trial name
- NCT03966014
- Testing
- EM-amoxicillin 3 x 10 days, EM-amoxicillin 3 x 14 days, Controls
- Where
- 2 sites in Slovenia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Rupture of Membranes; Delayed Delivery (Following Spontaneous Rupture), Rupture of Membranes; Premature
Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGA
This study is a non-blinded, prospective, randomized controlled trial designed to compare the effect of outpatient oral antibiotics (i.e., amoxicillin and azithromycin) on the length of time (days) that pregnancy continues after…
- Conditions
- Rupture of Membranes; Delayed Delivery (Following Spontaneous Rupture), Rupture of Membranes; Premature, Rupture of Membranes; Premature, Affecting Fetus, Preterm Birth
- Trial name
- NCT04047849
- Testing
- Antibiotics, oral Azithromycin and oral Amoxicillin
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Woman's
Healthy Volunteer, Pharmacokinetics
Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose Combination
This is a Phase 1, open-label, three-part, study in approximately 96 healthy adult participants between 18 and 55 years of age (both inclusive) (16 participants in Part 1, 20 participants in Part 2 and , and approximately 60…
- Conditions
- Healthy Volunteer, Pharmacokinetics, Safety, Drug-Drug Interaction (DDI)
- Trial name
- NCT06733675
- Testing
- Ledaborbactam etzadroxil, Ceftibuten, Ceftibuten-ledaborbactam etzadroxil
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Basilea Pharmaceutica
Gastric Cancer, H Pylori Infection
H. Pylori Screen-and-treat Study in a Population of Young Adults
Gastric cancer remains a major challenge to public health on a global scale. H. pylori related cancer burden contributes to the largest proportion of cancer cases attributable to infections in Europe.
- Conditions
- Gastric Cancer, H Pylori Infection, H Pylori Eradication, H-pylori
- Trial name
- NCT06275204
- Testing
- Bismuth-based quadruple therapy, Levofloxacin-based quadruple therapy, Standard triple therapy
- Where
- 7 sites in Croatia, Ireland and 4 more
- Volunteers
- 6,800 people, healthy volunteers welcome
- Sponsor
- University of Latvia
Alveolar Osteitis
Comparative Efficacy of Amoxicillin, Metronidazole, and Chlorhexidine in Preventing Alveolar Osteitis
This study will compare the effectiveness of amoxicillin, metronidazole, and chlorhexidine in preventing alveolar osteitis (dry socket) following lower third molar extraction.
- Trial name
- NCT07833176
- Testing
- Amoxicillin, Metronidazole, Chlorhexidine
- Where
- Pakistan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Acute Apical Abscess, Pain, Acute
Valacyclovir in Pain Management of Acute Apical Abscesses
The Virus in Endodontics (VE) phase I pilot study for preoperative pain will be analyzed and adjusted for the Phase II clinical trial.
- Trial name
- NCT05266040
- Testing
- Valacyclovir 500 MG
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy Adult Volunteers
Drug-Drug Interaction Between DW4421 and Amoxicillin/Clarithromycin
Drug-Drug Interaction between DW4421 and Amoxicillin/Clarithromycin
- Trial name
- NCT07382661
- Testing
- DW4421, DW4421-1, DW4421-2
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Antibiotic Prophylaxis
Use of Prophylactic Antibiotics Prior to OnabotulinumtoxinA
This study aims to show that lack of antibiotic prophylaxis to those undergoing bladder Botox injections is not significantly inferior to administering prophylaxis.
- Trial name
- NCT05519072
- Testing
- Nitrofurantoin
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Community-acquired Pneumonia
Twice Daily Treatment With Amoxicillin for Non-severe Community Acquired Pneumonia.
The aim of this study will be to evaluate whether a twice-daily antibiotic regimen is non-inferior to a thrice-daily regimen for the treatment of non-severe community acquired pneumonia in children presenting at a paediatric…
- Trial name
- NCT03031210
- Testing
- Amoxicillin
- Where
- Canada
- Volunteers
- 1,370 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital