Clinical trials: completed
Respiratory Syncytial Virus Infections
A Study on the Immune Response, Safety and the Occurrence of Respiratory Syncytial Virus (RSV)-Associated Respiratory Tract Illness After Administration of RSV OA Vaccine in Adults 60 Years and Older
The purpose of the current study is to evaluate the immune response of the RSVPreF3 OA investigational vaccine in older adults (OA) at least (>=) 60 years of age (YOA) in China compared to OA in the same age range to be enrolled…
- Trial name
- NCT06551181
- Testing
- RSVPreF3 OA investigational vaccine
- Where
- 40 sites in China, Finland and 5 more
- Volunteers
- 2,620 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Participants
A Study to Assess the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]-INCB161734 in Healthy Male Participants
This study is conducted to assess the mass balance, pharmacokinetics, and metabolite profiles of a single oral dose of [14C]-INCB161734 in healthy male participants.
- Trial name
- NCT07814404
- Testing
- INCB161734
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Incyte Corporation
Influenza
A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVSQIV in Healthy Adults
This study aims to evaluate the safety and reactogenicity profile of CVSQIV at different dose levels.
- Trial name
- NCT05252338
- Testing
- CVSQIV
- Where
- 3 sites in Panama
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- CureVac
Muscle Soreness
A Study to Evaluate the Analgesic Properties of Topically Applied Menthol in Marathon Participants
The purpose of the research study is to better understand the factors that impact pain experience in adult (18+ years) marathon runners participating in the 2026 Chicago Marathon and to better understand if topically applied…
- Trial name
- NCT07873242
- Testing
- Observational, Non-Interventional Study
- Where
- United States
- Volunteers
- 687 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Meningitis
A Phase 3 Study to Assess the Immune Response and Safety of rMenB+OMV NZ in Primed Healthy Participants (10 to 20 Years Old)
The main purpose of this study was to evaluate the immune response and safety of a booster dose of the meningococcal group B vaccine, rMenB+OMV NZ (also known as Bexsero), in adolescents and young adults aged 10 to 20 years.
- Trial name
- NCT06995430
- Testing
- rMenB+OMV NZ vaccine
- Where
- 17 sites in Finland, Italy and 2 more
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Safety Study
A Safety Study of IVMED-85 Ophthalmic Solution in Healthy Adults
The purpose of this trial is to determine the safety of IVMED-85 eye drops in healthy adult subjects. Participants will be assigned to either the active or vehicle eyedrop group.
- Trial name
- NCT07370584
- Testing
- IVMED-85 ophthalmic solution, Vehicle Ophthalmic Solution
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- iVeena Delivery Systems, Inc.
Diabetes, Diabetic Retinopathy
Pivotal Trial of Automated Artificial Intelligence (AI) Based System for Early Diagnosis of Diabetic Retinopathy
In this pivotal trial, the investigators aim to perform a prospective study to find the efficacy of iPredict-DR, an artificial intelligence (AI) based software tool on early diagnosis of Diabetic Retinopathy (DR) in the primary…
- Trial name
- NCT07151001
- Testing
- No intervention
- Where
- United States
- Volunteers
- 935 people, healthy volunteers welcome
- Sponsor
- iHealthScreen Inc
Alzheimer's Disease, Healthy Elderly
Study to Evaluate the Effects of NMRA-323511 Among Healthy Elderly and Adults With Agitation Associated With Dementia Due to Alzheimer's Disease
This study consists of 2 parts, Part A and Part B. Part A is a single center, randomized, double-blind, placebo-controlled cohort designed to evaluate the safety, tolerability, and pharmacokinetics (PK) of NMRA-323511 among…
- Trial name
- NCT06546995
- Testing
- NMRA-323511
- Where
- 26 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Neumora Therapeutics, Inc.
Bioequivalence, Male
An Open-label, Randomized, Single Oral Dose, Two-period, Two-sequence, Two-way, Crossover Bioequivalence Study on Healthy Adult Male Participants Under Fed Conditions to Compare, Test Product Palbociclib-EVAPHARMA 125 mg Hard Gelatin Capsule, Versus the Reference Product Ibrance™125 mg Capsules
Bioequivalence study of two Capsules formulation of Palbociclib in healthy male participants
- Trial name
- Palbociclib (NCT07922564)
- Testing
- Palbociclib-EVAPHARMA 125 mg Hard Gelatin Capsule, Ibrance capsules
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zi Diligence Biocenter
Pneumococcal Disease
A Study to Learn About the Safety and Immune Response of a New Pneumococcal Vaccine in Adults
The purpose of this study is to learn about the safety and immune effects of a pneumococcal vaccine in adults. This vaccine can possibly provide protection against further pneumococcal disease.
- Trial name
- NCT06182124
- Testing
- Multivalent Pneumococcal Vaccine - Formulation 1, Multivalent Pneumococcal Vaccine - Formulation 2, 20-valent pneumococcal conjugate vaccine (20vPnC)
- Where
- 17 sites in United States
- Volunteers
- 1,710 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
Effect of Food on Peposertib PK
The study investigated the effect of food on the Pharmacokinetic (PK) of a single dose of Peposertib administered as film-coated tablet under fed and fasted conditions.
- Trial name
- NCT04702698
- Testing
- Peposertib
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Dental Caries
In-situ Clinical Trial Assessing Ability to Detect and Monitor Active Caries and Their Remineralization
The goal of this clinical trial is to evaluate whether BlueCheck® can accurately detect and monitor early-stage dental caries (tooth decay) and their remineralization in adults.
- Trial name
- NCT07100626
- Testing
- BlueCheck
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Incisive Technologies Pty Ltd
Healthy
A Clinical Trial of Enlicitide and Rosuvastatin in Healthy Adults (MK-0616-039)
This goal of this trial is to learn about two medicines, enlicitide and rosuvastatin, in healthy people. Researchers will compare the amounts of enlicitide and rosuvastatin in a person's body over time, when they are given as…
- Trial name
- NCT07300280
- Testing
- MK-0616A, Enlicitide, Rosuvastatin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
T2DM (Type 2 Diabetes Mellitus)
Food Effect and Multiple-Dose Study of Chiglitazar/Metformin Extended-Release Tablets
This trial includes two parts: a food effect (FE) study and a multiple-dose pharmacokinetic (PK) study. The FE study is a randomized, open-label, two-period, two-sequence crossover study designed to evaluate the effect of a…
- Trial name
- NCT07511010
- Testing
- Chiglitazar/Metformin extended-release tablets under fasting conditions, Chiglitazar/Metformin extended-release tablets after a high-fat meal, multiple-dose of Chiglitazar/Metformin extended-release tablets
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Chipscreen Biosciences, Ltd.
Healthy Adults
A Study（Phase I）of GS3-007a Dry Suspension in Healthy Chinese Adults
This study consists of two parts: the first part is a single-dose escalating（SAD） and food effect （FE）study, and the second part is a multiple-dose (14-day) escalating(MAD) study.
- Trial name
- NCT07473570
- Testing
- GS3-007a for Suspension
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Healthy
PK, PD, Safety and Immunogenicity Study of Erythropoietin of Incepta Pharmaceuticals Ltd With Eprex (Janssen-Cilag).
Erythropoietin is a glycoprotein which stimulates red blood cell production. It is produced in the kidney and stimulates the division and differentiation of committed erythroid progenitors in the bone marrow.
- Trial name
- NCT07025681
- Testing
- Erythropoietin alfa
- Where
- Bangladesh
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Incepta Pharmaceuticals Ltd
Healthy Volunteer
A Study to Evaluate How Multiple Doses of Itraconazole Interacts With Nacresertib in Healthy Adult Participants
This study will evaluate how multiple doses of Itraconazole Impacts the performance of Nacresertib in healthy adult participants The goal of this study is to assess the safety and drug to drug interaction between Itraconazole and…
- Trial name
- NCT07649954
- Testing
- Nacresertib, Itraconazole
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AbbVie
Cheek Augmentation, Correction of Age-related Midface Contour Deficiencies
RHA®4 for Midface Volume Deficiency
This is a prospective, randomized, controlled, blinded evaluator, multicenter, between subjects clinical study to identify whether RHA4 is non-inferior to a comparator device for treatment of midface volume deficiency 8 weeks…
- Trial name
- NCT05133739
- Testing
- injection of RHA®4 in Midface, injection of Comparator Product in Midface
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Aging
Superficial MFU-V and Diluted Calcium Hydroxyapatite for the Improvement of Lower Face Skin Quality and Wrinkles
This single-center pilot study evaluated whether one treatment session combining superficial microfocused ultrasound with visualization (MFU-V, Ultherapy, 1.5 mm transducer) and diluted calcium hydroxylapatite (CaHA, Radiesse…
- Trial name
- NCT05469516
- Testing
- Ulthera System [Ulthera, Inc.], Merz Radiesse Injectable Implant
- Where
- Singapore
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cutis Medical Laser Clinics Pte Ltd
Hepatic Impairment
A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Hepatic Impairment Compared With Matched Healthy Participants
This was a Phase 1, open-label study to evaluate the PK, safety, and tolerability after administration of multiple doses of remibrutinib in participants with mild, moderate, or severe hepatic impairment (HI) compared to pooled…
- Trial name
- NCT05753592
- Testing
- Part 1; LOU064 (Remibrutinib), Part 2; LOU064 (Remibrutinib)
- Where
- Hungary
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.