Clinical trials: in Uganda
Low Weight for Age in Preschool Children
Effect of Mass Deworming on Child Growth
The purpose of the study was to determine whether periodical mass deworming improves growth in children below six years of age.
- Trial name
- NCT00344669
- Testing
- Albendazole 400 mg, given 6 monthly
- Where
- Uganda
- Volunteers
- 10,000 people
- Sponsor
- Makerere University
Trypanosomiasis, African
Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis
The treatment human African trypanosomiasis (HAT) in the meningoencephalitic phase relies on two molecules officially registered: melarsoprol, the most commonly used, has a poor safety profile and is becoming ineffective due to…
- Trial name
- NCT00330148
- Testing
- melarsoprol 1.8 mg/kg/d, 10d + nifurtimox 15/20 mg/kg/d, 10d, melarsoprol 1.8 mg/kg/d, 10d + eflornithine 400 mg/kg/d, 7d, nifurtimox 15/20 mg/kg/d 10d + eflornithine 400 mg/kg/d 7d
- Where
- Uganda
- Volunteers
- 435 people
- Sponsor
- Epicentre
Malnutrition
Ready to Use Therapeutic Food in the Rehabilitation of Severely Malnourished Children
Severe malnutrition is a major cause of child morbidity and mortality in developing countries especially sub-Saharan Africa. The hospital mortality rate due to severe malnutrition in developing countries ranges from 20-30%.
- Trial name
- NCT00131417
- Testing
- ready-to-use therapeutic food
- Where
- 2 sites in Norway, Uganda
- Volunteers
- 128 people
- Sponsor
- Makerere University
Cerebral Malaria
Efficacy of Intrarectal Versus Intravenous Quinine for the Treatment of Childhood Cerebral Malaria
Cerebral malaria is the most lethal complication of P.falciparum infection with a mortality rate between 5 and 40%. Intravenous quinine remains the recommended treatment for cerebral malaria.
- Trial name
- NCT00124267
- Testing
- Intrarectal quinine
- Where
- Uganda
- Volunteers
- 108 people
- Sponsor
- Makerere University
Cerebral Malaria
Mannitol as Adjunct Therapy for Childhood Cerebral Malaria
Cerebral malaria is a life-threatening complication of Plasmodium falciparum infection in African children and nonimmune travellers despite availability of quinine, the current drug of choice.
- Trial name
- NCT00113854
- Testing
- Mannitol
- Where
- Uganda
- Volunteers
- 156 people
- Sponsor
- Makerere University