Clinical trials: not yet recruiting, in Spain
Acute Respiratory Infection
Expanded Diagnostic Strategy in Older Adults Hospitalized With Community-Acquired Acute Respiratory Infection
This study will evaluate whether an expanded diagnostic strategy can reduce antibiotic use in patients aged 65 years or older who are hospitalized with community-acquired acute respiratory infection, without negatively affecting…
- Trial name
- NeuBluMul (NCT07883902)
- Testing
- Expanded Diagnostic Strategy, Conventional Diagnostic Strategy
- Where
- Spain
- Volunteers
- 406 people
- Sponsor
- Santiago Lopez Gil
Abdominal Aortic Aneurysm, Morbid Obesity
Pilot Study on the Effectiveness and Safety of OPTILENE® SILVER MESH ELASTIC in Prevention of Surgical Site Infection (SSI) and Incisional Hernia (IH)
The aim of the study is to describe the effectiveness of Optilene® Silver Mesh Elastic on prevention of surgical site infection (SSI) at 6 months follow-up in patients undergoing urgent laparotomy by collecting clinical data on…
- Trial name
- SSIHLVER (NCT06547138)
- Testing
- Prophylactic mesh
- Where
- 5 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Aesculap AG
Bipolar Disorder (BD), SCHIZOPHRENIA 1 (Disorder)
Sleep Monitoring for Early Detection of Relapse in People With Schizophrenia or Bipolar Disorder Receiving Usual Treatment
The goal of this observational study is to learn whether changes in sleep can help identify early signs of relapse in adults with schizophrenia or bipolar disorder.
- Trial name
- DESCANT (NCT07921667)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- International University of La Rioja
Retinal Artery Occlusion, Central Retinal Artery Occlusion
The GEIR (Grupo español de Ictus Retina) Registry: Rationale and Design of the First Nationwide Multicentre Retinal Stroke Registry in Spain
Retinal stroke is a time-dependent neurovascular emergency associated with severe visual loss, increased risk of cerebrovascular events and substantial variability in clinical management.
- Conditions
- Retinal Artery Occlusion, Central Retinal Artery Occlusion, Retinal Ischemia, Cilioretinal Arteries
- Trial name
- GEIR (NCT07900230)
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Germans Trias i Pujol Hospital
Acute Upper Respiratory Tract Infections, Nasal Obstruction
Influence of Patient Positioning During Nasal Lavage
Acute upper respiratory tract infections are the primary cause of pediatric visits and hospitalizations in young children. Nasal congestion and mucus accumulation often cause discomfort, feeding difficulties, and respiratory…
- Conditions
- Acute Upper Respiratory Tract Infections, Nasal Obstruction, Bronchiolitis
- Trial name
- nasal lavage (NCT07921680)
- Testing
- Supine position nasal lavage, Semi-sitting position nasal lavage
- Where
- Spain
- Volunteers
- 145 people
- Sponsor
- Hospital Universitario La Paz
Hypertension, Obesity
A Research Study to Investigate How Well the Medicine CagriSema Lowers High Blood Pressure in People Living With High Blood Pressure and Obesity
This study is testing whether CagriSema is safe and works well in adults with high blood pressure and excess body weight. Participants will receive CagriSema, semaglutide, cagrilintide, or placebo, and treatment will be assigned…
- Trial name
- REDEFINE (NCT07919405)
- Testing
- CagriSema, Semaglutide, Cagrilintide
- Where
- 212 sites in United States, Argentina and 17 more
- Volunteers
- 1,408 people
- Sponsor
- Novo Nordisk A/S
Post Menopausal Women
The Role of Diet Quality in Sleep Among Women in Postmenopause
This single-center, randomized controlled trial with parallel groups, consists of an intensive nutritional intervention based on a high-fiber Mediterranean diet (target intake: 30-35 g/day of dietary fiber), which will be…
- Trial name
- EMILE (NCT07918287)
- Testing
- Intensive High-Fiber Mediterranean Diet Counseling, Low-Intensity Mediterranean Diet Counseling
- Where
- Spain
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Alzheimer's Dementia (AD), Alzheimer Disease (AD)
Exercise in Alzheimer's Disease: Functional Biomarkers
Alzheimer's disease (AD) is the leading cause of dementia worldwide and involves systemic alterations beyond the brain, such as loss of muscle strength, chronic low-grade inflammation, and gut microbiome dysbiosis.
- Trial name
- AD-GUT-EX (NCT07918417)
- Testing
- High load, Moderate load, Healthy adults - High load
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- European University Miguel de Cervantes
Acute Ischemic Stroke
Efficacy and Safety Evaluation of iNstroke 5F Aspiration Catheter for Thrombectomy
Prospective, single-arm, multi-centre study to evaluate the efficacy and safety of the iNstroke 5F thromboaspiration catheter in patients with acute ischaemic stroke
- Trial name
- iNFLOW-5 (NCT07571954)
- Testing
- Thromboaspiration catheter
- Where
- 7 sites in France, Spain
- Volunteers
- 45 people
- Sponsor
- iVascular S.L.U.
Anorexia Nervosa Restricting Type, Anorexia Nervosa (DSM-IV Revised Criteria)
Biomarkers in EV Associated With Marrow Adiposity in Anorexia
The aim of this observational study is to identify biomarkers in extracellular vesicles associated with medullary adiposity occurring in patients with anorexia nervosa.
- Trial name
- VE_BMAT_AN (NCT06712485)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
C3 Glomerulopathy (C3G), Primary Immune-Complex Membranoproliferative Glomerulonephritis (IC-MPGN), Recurrent Glomerular Disease After Kidney Transplantation
A Study to Assess the Efficacy and Safety of Pegcetacoplan for the Prevention of Recurrent C3G or Primary IC-MPGN in Kidney Transplant Recipients
To assess the efficacy and safety of pegcetacoplan for the prevention of recurrent C3G or primary IC-MPGN in kidney transplant recipients
- Trial name
- PRESERVE (NCT07898774)
- Testing
- Pegcetacoplan
- Where
- 33 sites in Brazil, Canada and 8 more
- Volunteers
- 30 people
- Sponsor
- Swedish Orphan Biovitrum
Acute Lymphobkastic Leukemia, Adult
Inotuzumab as Post-Trasplantation Therapy for Adult High-risk B-cell Precursor Acute Lymphoblastic Leukemia
The goal of this clinical trial is to learn if Inotuzumab Ozogamicin works to prevent relapses after transplantation in adult high-risk B-cell precursor acute lymphoblastic leukemia treated with the PETHEMA ALL-2025 protocol.
- Trial name
- INOPOSALO (NCT07862946)
- Testing
- Inotuzumab Ozogamicin (IO)
- Where
- 10 sites in Spain
- Volunteers
- 30 people
- Sponsor
- PETHEMA Foundation
Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension
Home-based Inspiratory Muscle Training in Pulmonary Hypertension
The main objective of this study is to determine whether an 8-week inspiratory muscle training (IMT) programme, delivered at home through telerehabilitation, improves ventilatory efficiency (VE/VCO2 slope) compared with a sham…
- Trial name
- SLOPE-PH (NCT07917416)
- Testing
- Inspiratory muscle training
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Bronchiectasis
A Study to Learn How Well People With Bronchiectasis Tolerate Continued Treatment With Verducatib After Earlier Studies (AIRTIVITY®-ON)
This study is for adults and adolescents who are at least 12 years old and have bronchiectasis. People can participate if they completed a previous study with the study medicine called verducatib.
- Trial name
- NCT07915219
- Testing
- verducatib
- Where
- 383 sites in United States, Argentina and 37 more
- Volunteers
- 1,500 people
- Sponsor
- Boehringer Ingelheim
Neurologic Disorders
Advanced Multisensorial System for Automatic Assessment of Neurological Disorders in Smart Spaces-Universidad Rey Juan Carlos (URJC)
Neurological diseases affect people's cognitive and physical abilities, limiting their functional independence and causing disability, which in many cases, is progressive and degenerative.
- Trial name
- NeurEYE-URJC (NCT07909824)
- Testing
- NeurEYE: healthy people, NeurEYE: people with neurological diseases
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Trauma, Psychological, Traumatic Stress Disorder
Magnetoencephalographic Correlates of Clinical Change After Cognitive Processing Therapy in Adults With PTSD
Cognitive Processing Therapy (CPT) is a first-line, evidence-based trauma-focused treatment for posttraumatic stress disorder (PTSD), but the clinical and neurophysiological mechanisms underlying therapeutic response remain…
- Trial name
- REC-HEALING-TR (NCT07917377)
- Testing
- Behavioral: Cognitive Processing Therapy (individual), Magnetoencephalography (MEG)
- Where
- 2 sites in Spain
- Volunteers
- 10 people
- Sponsor
- Universidad Complutense de Madrid
Cardiopulmonary Resuscitation, Out-of-Hospital Cardiac Arrest
Compression-Only Versus Standard Basic Life Support Training in Nursing Students
Survival after out-of-hospital cardiac arrest rarely exceeds 10%, and cardiopulmonary resuscitation (CPR) started by bystanders is a key factor for survival.
- Trial name
- NCT07915778
- Testing
- BLS and AED Training With Rescue Breaths, BLS and AED Training Without Rescue Breaths
- Where
- Spain
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Colitis, Ulcerative, Crohn Disease
A Real-World Study of Guselkumab Persistence and Effectiveness in Participants With Crohn's Disease or Ulcerative Colitis
The purpose of this study is to evaluate how long participants with moderate-to-severe Crohn's Disease (CD) and Ulcerative Colitis (UC) continue treatment with guselkumab in a real-world setting.
- Trial name
- GALILEO (NCT07848737)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Janssen-Cilag, S.A.
Eating Disorders, Body Image Dissatisfaction
Development, Implementation, and Evaluation of the HADAS Program for the Prevention of Eating Disorders in Adolescent Female Athletes, Coaches, and Families.
Adolescent female athletes in aesthetic sports disciplines (such as rhythmic gymnastics, artistic gymnastics, synchronized swimming, and figure skating) face a complex interaction between general sociocultural beauty pressures…
- Trial name
- The HADAS (NCT07750301)
- Testing
- The HADAS Program
- Where
- Spain
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Urinary Incontinence (UI)
Clinical, Functional, and Therapeutic Characterization of Women With Urinary Incontinence and Analysis of Factors Associated With Treatment Response
The goal of this observational retrospective study is to characterize women with urinary incontinence and to identify factors associated with their response to treatment using artificial intelligence models.
- Trial name
- XINE-IA (NCT07887464)
- Testing
- Artificial intelligence clinical decision support model
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Javier Pereira