Clinical trials: open to volunteers, in Norway
Breast Cancer Patients, Health, Subjective
Coping After Breast Cancer - a Randomized Clinical Trial With Two Digital Interventions
1. Breast cancer patients and age-matched controls are first invited to answer questions on HRQoL. 2. Among responding breast cancer patients, a subset are invited in a randomized clinical trial with two digital interventions for…
- Trial name
- CABC (NCT04480203)
- Testing
- Stressproffen cognitive based stress management, Stressproffen mindfulness based intervention, Control
- Where
- Norway
- Volunteers
- 390 people
- Sponsor
- Norwegian Institute of Public Health
Pediatric Respiratory Diseases, COVID
COVID-19 in Hospitalised Norwegian Children - Risk Factors, Outcomes and Immunology
Prospective cohort study of COVID-19 infection among children in Norway.
- Conditions
- Pediatric Respiratory Diseases, COVID, Fatigue Post Viral
- Trial name
- NCT04335773
- Where
- Norway
- Volunteers
- 350 people
- Sponsor
- University Hospital, Akershus
Coronavirus
Risk Factors for Community- and Workplace Transmission of COVID-19
The project is an epidemiological observational study based on an electronic questionnaire on risk factors for COVID-19 in the community and healthcare setting.
- Trial name
- NCT04320732
- Testing
- Observation of behavior and COVID-19 infection will be conducted.
- Where
- Norway
- Volunteers
- 250,000 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
AML, Adult, MDS
Precision Therapy Versus Standard Therapy in AML and MDS in Elderly
This is a randomized clinical trial that randomizes between treatment principles. The study will investigate if precision therapy determined by a tumour board is better than standard treatment for acute myeloid leukaemia (AML)…
- Trial name
- PALM (NCT05025098)
- Testing
- Standard therapy, Precision therapy
- Where
- Norway
- Volunteers
- 36 people
- Sponsor
- University Hospital, Akershus
Pseudomyxoma Peritonei, Colorectal Carcinoma
Peritoneal Surface Malignancies - Characterization, Models and Treatment Strategies
The aim of this study is to identify biomarkers of disease recurrence and prognosis to optimize patient selection for treatment with cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC), and through…
- Conditions
- Pseudomyxoma Peritonei, Colorectal Carcinoma, Ovarian Carcinoma, Mesothelioma
- Trial name
- PSM (NCT02073500)
- Testing
- Observational study.
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Oslo University Hospital
Depression, Cost Benefit Analysis
Dysthymia: Associated Costs, Treatment and Change Process
The study evaluates cost and effect of inpatient versus outpatient treatment of dysthymia, as well as investigates the processes through which psychotherapy works in treating dysthymia.
- Conditions
- Depression, Cost Benefit Analysis, Psychotherapeutic Processes
- Trial name
- DFront (NCT04911829)
- Testing
- Psychotherapy
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Modum Bad
Mitral Regurgitation
Tendyne European Experience Registry
TENDER is a multicenter, single-device, retrospective and prospective, observational study to assess safety and efficacy of the Tendyne Mitral Valve System in a real-world population.
- Trial name
- TENDER (NCT04898335)
- Testing
- Tendyne Mitral Valve System
- Where
- 30 sites in Austria, Belgium and 8 more
- Volunteers
- 400 people
- Sponsor
- LMU Klinikum
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
A Pilot Study on Intermittent Ibrutinib in Patients With Advanced-phase Chronic Lymphocytic Leukemia (CLL)
Ibrutinib, an inhibitor of Bruton´s tyrosine kinase (BTK) is approved in CLL as continuous, daily administration of 420 mg orally until progression.
- Trial name
- IbruOnOff (NCT04771507)
- Testing
- Ibrutinib
- Where
- 9 sites in Norway, Sweden
- Volunteers
- 50 people
- Sponsor
- Jeanette Lundin
Local Neoplasm Recurrence, Distantly Metastatic Malignant Neoplasm
Partial Breast Versus no Irradiation for Women With Early Breast Cancer
All early breast cancer patients are offered adjuvant breast radiation therapy (RT) after breast conserving surgery for an early breast cancer.
- Conditions
- Local Neoplasm Recurrence, Distantly Metastatic Malignant Neoplasm, Death, Fibrosis Breast
- Trial name
- NCT03646955
- Testing
- No partial breast irradiation
- Where
- 17 sites in Chile, Denmark and 2 more
- Volunteers
- 926 people
- Sponsor
- Danish Breast Cancer Cooperative Group
Massive Rotator Cuff Tears
Arthroscopic Treatment of Massive Rotator Cuff Tears With Debridement and Biodegradable Spacer.
Massive rotator cuff tears are common in the adult population. It is estimated that about 12 % of adults 60 years of age or older suffer from a rotator cuff injury.
- Trial name
- AMRIS (NCT04571918)
- Testing
- Biodegradable spacer, Debridement and biceps tenotomy
- Where
- 2 sites in Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Breast Cancer
Prospective Breast Cancer Biobanking
Prospective Breast Cancer Biobanking study (PBCB) will apply advanced monitoring in liquid biopsies of early staged breast cancer ration in order to facilitate A.
- Trial name
- PBCB (NCT04488614)
- Testing
- Breast Concervative or Meastectomy
- Where
- 2 sites in Norway
- Volunteers
- 1,200 people
- Sponsor
- Helse Stavanger HF
Self Harm, Suicide, Attempted
Emotional Dysregulation in Para-suicidal Behavior
This is a naturalistic cohort pre-post study investigating aspects of emotional processing and how possible changes in emotional processing is related to the successful treatment of non-suicidal self-injury and suicidal ideation…
- Conditions
- Self Harm, Suicide, Attempted, Emotional Instability, Borderline Personality Disorder
- Trial name
- NCT03846375
- Testing
- Psychotherapy, Pre-intervention testing
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Myeloma, Multiple, PET-CT
Fluciclovine PET/CT in Multiple Myeloma Patients
Comparison between image findings at aminoacid PET/CT and FDG PET/CT for myeloma patients
- Trial name
- FLUCIPET (NCT03966443)
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Oslo University Hospital
Diabetes Mellitus, Pancreas Transplantation
The Norwegian Pancreas Transplantation (PTx) Study
Several studies have shown acceptable results after Pancreas Transplantation (PTx) by substituting ATG with basiliximab, which is considered to convey a considerably lower number of adverse events.
- Conditions
- Diabetes Mellitus, Pancreas Transplantation, Allograft Rejection, Surgical Complication Nec
- Trial name
- PTx (NCT01957696)
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Hypertension
Nesiritide in Hypertension
Hypertension remains a global burden in cardiovascular disease leading to stroke, myocardial infarction, and heart failure. Its myocardial complications result from increased mechanical load on the heart.
- Trial name
- TENSE1 (NCT02608996)
- Testing
- Nesiritide
- Where
- 3 sites in Norway
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Late Onset Sporadic Cerebellar Ataxia
Sporadic Degenerative Ataxia With Adult Onset: Natural History Study
The key goals of SPORTAX-NHS is to compare the phenotype of multiple system atrophy of cerebellar type (MSA-C) and sporadic adult onset ataxia of unknown aetiology (SAOA) and to determine the rate of disease progression in both…
- Trial name
- SPORTAX-NHS (NCT02701036)
- Where
- 14 sites in Austria, Germany and 3 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ataxia Study Group
Endometrial Cancer
Biomarker Guided Treatment in Gynaecological Cancer
MoMaTEC2 aims to test, in clinically oriented studies, the applicability of already identified and promising molecular biomarkers, to promote individualisation of treatment for patients with endometrial cancer.
- Trial name
- Momatec2 (NCT02543710)
- Testing
- Biomarker (ER/PR) guided lymphadenectomy, Biomarker guided weekly taxane treatment in endometrial/ ovarian cancer
- Where
- 9 sites in Netherlands, Norway and 1 more
- Volunteers
- 1,300 people
- Sponsor
- Haukeland University Hospital