Clinical trials: open to volunteers, in Iran
Pain Management, Nursing Education
ChatGPT-Driven Blended Teaching for Pain Management in Nursing Students: A Randomized Controlled Trial
Pain management is a core competency in nursing practice, yet nursing students consistently demonstrate insufficient knowledge, unfavorable attitudes, limited competence, and low self-efficacy in this area.
- Conditions
- Pain Management, Nursing Education, Knowledge, Attitudes, Practice
- Trial name
- NCT07552363
- Testing
- ChatGPT-Driven Blended Teaching Model for Pain Management, Traditional Clinical Nursing Rounds
- Where
- Iran
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Acute Low-back Pain
The Effect of Integrating Pain Neuroscience Education(PNE) With Conventional Physiotherapy on Pain and Functional Disability in Patients With Acute Low Back Pain
Acute low back pain is one of the most common health problems in the world. Most people experience it at least once in their lives, and although many cases improve within a few weeks, a significant number of patients continue to…
- Trial name
- NCT07277517
- Testing
- routine physiotherapy + traditional patient education, pain neuroscience education
- Where
- Iran
- Volunteers
- 48 people
- Sponsor
- Iran University of Medical Sciences
Tirzepatide
Tirzepatide (Spartina) in Obese Kidney Transplant Recipients
Post-transplant obesity is a common complication after kidney transplantation, largely attributed to recovery from uremia, increased appetite, sedentary lifestyle, and long-term corticosteroid exposure.
- Trial name
- NCT07423247
- Testing
- Tirzepatide
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Kidney Transplant Rejection
Treatment of Chronic Active Antibody Mediated Rejection With Tocilizumab
Chronic active antibody mediated rejection (CAMR) is a therapeutic challenge in transplant recipients that does not respond well to conventional treatments for acute antibody mediated rejection (AMR).
- Trial name
- NCT07006532
- Testing
- Tocilizumab
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Pterygium of the Conjunctiva and Cornea
Conjunctival Transpositional Surgery for Primary Pterygium
This prospective single-arm interventional study evaluates the recurrence rate and functional outcomes following conjunctival transpositional pterygium surgery without bare sclera formation.
- Trial name
- NCT07343011
- Testing
- Conjunctival Transpositional Pterygium Surgery
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Zahedan University of Medical Sciences
Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus
Clinical Trial Investigating the Effect of Exosomes as a Complementary Treatment in Severe to Moderate Erectile Dysfunction
The goal of this clinical trial is to Investigate the Effect of Injection of MSC-Derived Exosome on Patients with Erectile Dysfunction in overall healthy males, aged 18-70, with-out any severe active medical condition, with…
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus, Erectile Dysfunction Due to Arterial Disease, Erectile Dysfunction Due to Arterial Insufficiency
- Trial name
- MSC (NCT07319533)
- Testing
- exosomes derived from human umbilical cord mesenchymal stem cells, Normal (0.9%) saline
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Labbafinejad Medical Center
Advanced Basal Cell Carcinoma (BCC), Inoperable Disease
Treatment of Basal Cell Carcinoma (BCC) of the Skin, of the Morpheiform, Infiltrative, and Noduloulcerative Types in Inoperable Patients and Not Suitable for Radiotherapy Using Formulated Methylene Blue
The goal of this clinical trial is to evaluate whether formulated methylene blue can safely and effectively treat advanced or inoperable basal cell carcinoma (BCC), a common type of skin cancer.
- Conditions
- Advanced Basal Cell Carcinoma (BCC), Inoperable Disease, Morpheaform Basal Cell Carcinoma, Noduloulcerative Basal Cell Carcinoma
- Trial name
- NCT07311070
- Testing
- Formulated Topical Methylene Blue (0.5 mg/mL), Wound Healing Gel
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Daryoush Hamidi Alamdari, PhD
SCC - Squamous Cell Carcinoma, SCC - Squamous Cell Carcinoma of Skin
Investigation of Effect of Formulated Methylene Blue on Treatment of Squamous Cell Carcinoma Skin Cancer in Inoperable Patients and Not Suitable for Radiotherapy
The goal of this clinical trial is to evaluate whether formulated methylene blue can safely and effectively treat advanced or inoperable Squamous Cell Carcinoma (SCC), a common type of skin cancer.
- Conditions
- SCC - Squamous Cell Carcinoma, SCC - Squamous Cell Carcinoma of Skin, Inoperable Disease
- Trial name
- NCT07311057
- Testing
- Formulated Topical Methylene Blue (0.5 mg/mL), Wound Healing Gel
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Daryoush Hamidi Alamdari, PhD
Polycystic Ovary Syndrome (PCOS)
Effect of Magnesium and Levocarnitine on Metabolic and Clinical Outcomes in Women With Polycystic Ovarian Syndrome (PCOS)
Polycystic Ovary Syndrome (PCOS) is one of the most common endocrine disorders among women of reproductive age and is associated with metabolic abnormalities such as insulin resistance, dyslipidemia, and hormonal imbalance, which…
- Trial name
- NCT07298564
- Testing
- Magnesium 500 mg, Levocarnitine 1000 mg
- Where
- Iran
- Volunteers
- 84 people
- Sponsor
- Behnood Abbasi
Common Warts
Topical 5-Fluorouracil (5FU) Plus Calcipotriol in Children With Palmoplantar Wart
Warts caused by the human papillomavirus (HPV) are one of the most common skin conditions among children. The prevalence of warts in school-aged children ranges from 10 to 20 percent.
- Trial name
- NCT06737406
- Testing
- Topical 5% fluorouracil cream, Topical 0.005% calcipotriol ointment
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Mazandaran University of Medical Sciences
Obesity
Efficacy and Safety of Tirzepatide (Spartina) in Chronic Kidney Failure
Diabetes management presents a complex clinical scenario marked by several challenges, especially in chronic kidney failure. These include navigating potential drug interactions between oral antidiabetic therapies and other…
- Trial name
- Tirzepatide (NCT07176663)
- Testing
- Tirzepatide
- Where
- Iran
- Volunteers
- 15 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Anthracycline-induced Cardiac Toxicity, Breast Cancer
Rosuvastatin for Prevention of Anthracycline-induced Cardiac Dysfunction in Breast Cancer Patients
This study, called "ROSUBREAST", is a multicenter, double-blind, randomized clinical trial evaluating whether rosuvastatin (20 mg daily) can protect the heart in women with breast cancer receiving anthracycline-based…
- Conditions
- Anthracycline-induced Cardiac Toxicity, Breast Cancer, Anthracycline Related Cardiotoxicity in Breast Cancer, Anthracycline-induced Cardiotoxicity
- Trial name
- ROSUBREAST (NCT07254221)
- Testing
- Rosuvastatin 20 mg/day
- Where
- 7 sites in Iran
- Volunteers
- 400 people
- Sponsor
- Shiraz University of Medical Sciences
Dystrophic Epidermolysis Bullosa, Wound Heal
Effect of Ev.FV on Wound Healing in Dystrophic Epidermolysis Bullosa
Epidermolysis bullosa (EB) is a hereditary disease of skin tissues that causes painful bleeding blisters in the skin and mucous membrane. The prevalence of this disease is 1 in 50,000.
- Trial name
- NCT07230223
- Testing
- Ev.FV 1.0 x 1011 par/ml
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Isfahan University of Medical Sciences
Port-A-Cath
Comparison of Outcomes of Right Internal Jugular Port Implantation in Patients With Right Versus Left Breast Cancer Undergoing Chemotherapy
Chemotherapy is an essential component of breast cancer treatment. Frequent intravenous injections may lead to phlebitis and limited venous access, therefore implantable venous ports are increasingly used.
- Trial name
- NCT07197320
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Golestan University of Medical sciences
Diabetic Foot Ulcer, Diabetes Complications
Characteristics of Diabetic Foot Ulcer Patients
This study examines the demographic, clinical, and laboratory characteristics of patients with diabetic foot ulcers admitted to 5 Azar Hospital, Gorgan, in 2024.
- Trial name
- NCT07188337
- Where
- Iran
- Volunteers
- 200 people
- Sponsor
- Golestan University of Medical sciences
Pancreatitis, Acute, EUS Guided Biopsy
EUS-guided FNB-induced PANCREatitis Assessment
This is a descriptive analytical study to investigate the prevalence and risk factors for pancreatitis after Endoscopic Ultrasonography-guided Fine Needle Biopsy (EUS-FNB) in patients at Shariati Hospital in Tehran.
- Trial name
- EUS-PANCREA (NCT07168863)
- Testing
- EUS-guided FNB
- Where
- Iran
- Volunteers
- 300 people
- Sponsor
- University of Tehran
Osteoarthritis, Knee
Mesenchymal Stem Cells Derived Exosomes in Osteoarthritis Patients
Present research focuses on the potential of exosomes, which are small vesicles secreted by mesenchymal stem cells (MSCs), as a therapeutic approach for osteoarthritis (OA).
- Trial name
- NCT06466850
- Testing
- Exosome
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Isfahan University of Medical Sciences
Mid Face Volume Deficit
Evaluation of Efficacy and Safety of Alcarisa (Hyaluronic Acid Produced by Espad Pharmed Co.) for Restoration of Mid-face Volume
Mid-face volume loss is a factor affecting beauty that makes people feel uncomfortable about themselves. The purpose of this study is to evaluate the efficacy and safety of Hyaluronic Acid injection with the brand name Alcarisa®…
- Trial name
- NCT07126912
- Testing
- Alcarisa (hyaluronic acid filler)
- Where
- 2 sites in Iran
- Volunteers
- 30 people
- Sponsor
- Espad Pharmed
Suicide, Suicide Ideation
Randomized Suicide Prevention Trial Using ASSIP and ACT in Suicide Attempters
This is a randomized controlled trial that aims to compare the effectiveness of two psychological treatment approaches: the Attempted Suicide Short Intervention Program (ASSIP) and Acceptance and Commitment Therapy (ACT).
- Trial name
- NCT07132099
- Testing
- Attempted Suicide Short Intervention Program (ASSIP), Acceptance and Commitment Therapy (ACT), Treatment as Usual (TAU)
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Ardakan University
Keratoconus
The K-Map Study, Global Prevalence of KC
Keratoconus is a ocular disease classified under ectatic diseases which often results in bilateral and asymmetrical corneal distortion. It usually affects patients at young age and can cause severe visual loss.
- Trial name
- NCT03115710
- Testing
- Rotating Scheimpflug camera (Pentacam HR)
- Where
- 12 sites in United States, China and 10 more
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva