Clinical trials: open to volunteers, in Iceland
Frailty in Adult Surgery, Frailty Syndrome
Validity of Frailty Screening Tools as a Measure for Postoperative Outcomes
Frailty is a common geriatric syndrome defined as a clinical state of decreased physiologic reserve resulting in increased vulnerability to stressors.
- Conditions
- Frailty in Adult Surgery, Frailty Syndrome, Elective Surgery
- Trial name
- NCT07367828
- Testing
- Intermediate/major elective surgery
- Where
- Iceland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Cirrhoses, Liver
Nursing Needs of Patients With Cirrhosis
The primary objective of this study is to examine the quality of life, disease-related knowledge, and perceived nursing needs of adult patients diagnosed with liver cirrhosis who attend the outpatient clinic at Landspítali…
- Trial name
- NCT07273331
- Testing
- blood sample, blood samples for analysis of cirrhosis
- Where
- 2 sites in Iceland
- Volunteers
- 150 people
- Sponsor
- Landspitali University Hospital
Non-Muscle Invasive Bladder Cancer
Chemoablation Or Bladder Resection With Adjuvant Chemotherapy in Recurrent Non-Muscle Invasive Bladder Cancer
The investigartors will conduct a randomized, multinational study with the aim to assess if the efficacy of a dose dense chemoablation with Mitomycin C (MMC) with adjuvant BCG in non-responding patients is superior regarding long…
- Trial name
- COBRA-NMIBC (NCT06781879)
- Testing
- Mitomycin c
- Where
- 8 sites in Denmark, Iceland and 2 more
- Volunteers
- 272 people
- Sponsor
- Jakob Kristian Jakobsen
Surgical Scars
Evaluation of the Scar Healing Effects of ChitoCare Medical Scar Healing Gel in Women Undergoing Breast Reduction or Mastopexy Surgery (CHITOSCAR)
Patients undergoing breast reduction or mastopexy surgery will be screened and recruited for participation in the study. Eligible patients will act as their own control with one breast receiving the active intervention…
- Trial name
- CHITOSCAR (NCT06992960)
- Testing
- ChitoCare® medical Scar Healing Gel (Örsáragel), Amoena CuraScar Mammilla Circles Silicone Scar Patch and Amoena CuraScar Anchors Silicone Scar Patch
- Where
- Iceland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Primex ehf
Aortic Dissection
Scandinavian Trial of Uncomplicated Aortic Dissection Therapy
The introduction of thoracic endovascular aortic repair (TEVAR) in 1994 has radically changed the treatment of thoracic aortic pathology, and TEVAR is now the recommended therapy for "complicated" TBADs and other thoracic aorta…
- Trial name
- SUNDAY (NCT05215587)
- Testing
- TEVAR
- Where
- 28 sites in Denmark, Finland and 4 more
- Volunteers
- 554 people
- Sponsor
- University of Aarhus
Breast Cancer, Cancer
Digital Patient Support Program for Self-efficacy and Medication Adherence in Women on Adjuvant Endocrine Treatment for Breast Cancer
This is a randomized, controlled study to assess the effect of Sidekick Health's digital program on self-efficacy and medication adherence in breast cancer patients prescribed adjuvant anti-hormonal treatment.
- Trial name
- NCT06989450
- Testing
- Sidekick digital patient support program for patients with breast cancer, Standard of care for breast cancer patients
- Where
- Iceland
- Volunteers
- 140 people
- Sponsor
- Sidekick Health
Bipolar Depression
Behavioural Activation for Bipolar Depression
Bipolar disorder (BD) affects between 1-3% of the world's population. People with BD experience episodes of mania or hypomania and in most cases, they experience periods of depression which can cause difficulties in daily life.
- Trial name
- NCT06022913
- Testing
- Behavioural Activation (BA)
- Where
- Iceland
- Volunteers
- 10 people
- Sponsor
- Reykjavik University
Infant, Premature, Diseases, Birth, Preterm
The NEU-STIM Trial
The aim of this study is to determine the effect of repetitive tactile stimulation compared to selective stimulation on oxygenation of the infant at 5 minutes after birth.
- Trial name
- NEU-STIM (NCT05942924)
- Testing
- Repeated tactile stimulation, Selective tactile stimulation
- Where
- 43 sites in Austria, Belgium and 17 more
- Volunteers
- 3,280 people
- Sponsor
- Leiden University Medical Center
Solid Tumor
Feasibility of Switching Fluoropyrimidine Due to Cardiotoxicity Study
The purpose of the present study is to evaluate cardiotoxicity during re-challenge of a different modality of fluoropyrimidine (primary end-point S-1 and secondary any other fluoropyrimidine) after having perceived cardiotoxicity…
- Trial name
- CardioSwitch (NCT04260269)
- Testing
- Fluoropyrimidine
- Where
- 13 sites in Denmark, Finland and 5 more
- Volunteers
- 200 people
- Sponsor
- Helsinki University Central Hospital
Chronic Kidney Diseases, Atrial Fibrillation
Stroke Prophylaxis With Apixaban in Chronic Kidney Disease Stage 5 Patients With Atrial Fibrillation
Objective: To study the efficacy and safety of apixaban as stroke prophylaxis in patients with chronic kidney disease (CKD) stage 5 and atrial fibrillation (AF) with or without dialysis treatment.
- Conditions
- Chronic Kidney Diseases, Atrial Fibrillation, Stroke, Intracerebral Hemorrhage
- Trial name
- SACK (NCT05679024)
- Testing
- Apixaban 2.5 milligram Oral Tablet
- Where
- 34 sites in Finland, Iceland and 2 more
- Volunteers
- 1,400 people
- Sponsor
- Region Stockholm
HIV, Hepatitis B
EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV
The EuroSIDA study is a prospective observational cohort study of 23,000+ patients followed in 100+ clinics in 35 European countries, Israel and Argentina.
- Conditions
- HIV, Hepatitis B, Hepatitis C, AIDS
- Trial name
- EuroSIDA (NCT02699736)
- Where
- 110 sites in Argentina, Austria and 34 more
- Volunteers
- 23,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Oppositional Defiant Disorder
Emotion Regulation as a Moderator of Two Different Treatments for Children With ODD
The goal of this randomized controlled trial is to is to test emotion regulation as a moderator of two different treatments for children with Oppositional Defiant Disorder (ODD).
- Trial name
- NCT06194994
- Testing
- Parent Management Training, Tuning Your Temper
- Where
- Iceland
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Hepatitis C
Treatment as Prevention for Hepatitis C in Iceland
The main aim of this study is to test in the Icelandic population the hypothesis that a nationwide treatment program which offers effective treatment to all known cases of Hepatitis C with the aim of halting HCV (Hepatitis C…
- Trial name
- TraPHepC (NCT02647879)
- Where
- Iceland
- Volunteers
- 1,000 people
- Sponsor
- Landspitali University Hospital
Multiple Myeloma, Smoldering Multiple Myeloma
A Nationwide Phase 2 Trial of Patients With Smoldering and Active Multiple Myeloma (MM)
The purpose of this study is to determine the efficacy of treating patients with intermediate risk smoldering multiple myeloma (SMM) with combinational therapy with dexamethasone and lenalidomide (Rd) and patients with high risk…
- Trial name
- iStopMM (NCT03815279)
- Testing
- Carfilzomib, Lenalidomide, Dexamethasone
- Where
- Iceland
- Volunteers
- 80 people
- Sponsor
- Landspitali University Hospital