Clinical trials: in Hong Kong
Prostate Cancer
Patient and Physician Benefit/ Risk Preferences for Treatment of mPC in Hong Kong: a Discrete Choice Experiment
The objective of this study is to examine the preference weightings in term of risk/ benefit attributes of treatment in physician and prostate cancer patients from different stages of disease.
- Trial name
- NCT05761093
- Where
- Hong Kong
- Volunteers
- 350 people
- Sponsor
- Chinese University of Hong Kong
Urolithiasis
Renal Stone Treatment Global Registry
This is an international prospective data registry to assess the treatment outcomes and complications of different treatment approaches for different surgical treatment of urolithiasis.
- Trial name
- NCT05297331
- Where
- 3 sites in Hong Kong
- Volunteers
- 3,000 people
- Sponsor
- Chinese University of Hong Kong
Resilience, Anxiety
Music Breathing in Enhancing Resilience Among Elders at Risk of Mental Health Problems
The goal of this pilot randomised controlled trial is to examine the effects of a mindfulness-based music breathing intervention in enhancing resilience (primary outcome), and in reducing anxiety, depressive symptoms, loneliness…
- Conditions
- Resilience, Anxiety, Depressive Symptom, Loneliness
- Trial name
- NCT07631845
- Testing
- Mindfulness-based music breathing intervention, control group
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Voiding Dysfunction, Substance Abuse
Treatment Outcomes Under a Standardized Treatment Protocol in Patients Suffered Substance Abuse Related Voiding Dysfunction
With the increase of substance abuse over the world, substance abuse e.g. ketamine and methamphetamine related voiding dysfunction is becoming an important medical problem.
- Trial name
- NCT03913819
- Testing
- First line treatment: oral NSAID and anticholinergic agents, Second line treatment: additional treatment for pain control, Third line treatment: A course of intravesical hyaluronate will be given.
- Where
- Hong Kong
- Volunteers
- 1,000 people
- Sponsor
- Chinese University of Hong Kong
Cancer
To Identify Potential New Urine Marker Panel for Cancer Screening
Polyamines are naturally produced metabolites in our cells. There were some reports suggested the urinary levels of polyamines were altered in patients with different cancers.
- Trial name
- NCT04689802
- Where
- Hong Kong
- Volunteers
- 2,500 people
- Sponsor
- Chinese University of Hong Kong
Pain, Acute, Pain, Chronic
Butyrate and Taurine for Chronic Postsurgical Pain in Adult Cardiac Surgical Patients
This study is a single-center, phase II, randomized, placebo-controlled, Bayesian-designed, double-blinded trial Goal and Questions: The primary goal is to evaluate if a combination of taurine and butyrate can reduce chronic…
- Conditions
- Pain, Acute, Pain, Chronic, Chronic Post Operative Pain
- Trial name
- NCT07144033
- Testing
- Butyrate and Taurine
- Where
- Hong Kong
- Volunteers
- 216 people
- Sponsor
- Chinese University of Hong Kong
Chronic Obstructive Pulmonary Disease (COPD)
A Study on COPD Phenotypes, Endotypes and Treatable Traits
Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous and multisystemic disease with progressive increasing morbidity and mortality.
- Trial name
- NCT06952881
- Where
- Hong Kong
- Volunteers
- 460 people
- Sponsor
- Chinese University of Hong Kong
Older Adults (60 - 85 Years Old), Self-care
Acceptance-based Self-care Intervention for Older Adults With Multimorbidity
The proposed 27-month three-arm parallel, repeated measure, randomized controlled trial aims to evaluate an acceptance-based self-care intervention for community-dwelling older adults with multimorbidity.
- Conditions
- Older Adults (60 - 85 Years Old), Self-care, Multimorbidity
- Trial name
- NCT07882992
- Testing
- Acceptance-based activities, Self-care activities
- Where
- Hong Kong
- Volunteers
- 306 people
- Sponsor
- Chinese University of Hong Kong
Scoliosis; Adolescence, Adolescent
Quality of Life (HRQoL) of AIS Patients Who Require Bracing or Surgery Using SRS-22 Questionnaire
Adolescent Idiopathic Scoliosis (AIS) is an unexpected curvature of spine at teenage. AIS causes mainly unpleasant appearance, and sometime comes with pain and difficult to locate or move around.
- Conditions
- Scoliosis; Adolescence, Adolescent, Quality of Life, SRS
- Trial name
- QolAISSRS22 (NCT03915106)
- Testing
- Brace, Surgical correction using implants
- Where
- Hong Kong
- Volunteers
- 2,000 people
- Sponsor
- Chinese University of Hong Kong
Benign Prostatic Hyperplasia
Perioperative Parameter and Treatment Outcomes of Surgical Treatment for Benign Prostate Hyperplasia in Hong Kong
This is a prospective data registry to assess the treatment outcomes and complications of different treatment approaches in our hospital clusters.
- Trial name
- NCT05292235
- Where
- 3 sites in Hong Kong
- Volunteers
- 2,000 people
- Sponsor
- Chinese University of Hong Kong
Endometrial Cancer
Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26)
The goal of this clinical study is to find out how the study drug, sacituzumab govitecan (SG) works in participants with endometrial cancer who have received prior treatment with platinum-based chemotherapy and immunotherapy…
- Trial name
- ASCENT-GYN-01 (NCT06486441)
- Testing
- Sacituzumab govitecan-hziy, Doxorubicin, Paclitaxel
- Where
- 189 sites in United States, Australia and 17 more
- Volunteers
- 640 people
- Sponsor
- Gilead Sciences
Prostate Cancer
The Effect of Pulsed Electromagnetic Field Therapy on Muscle Mass and Muscle Strength in Prostate Cancer Patients Treated With Androgen Deprivation Therapy
This study is to assess the effect of Pulsed electromagnetic fields (PEMF) on improving muscle mass and strength in prostate cancer patients with ADT.
- Trial name
- NCT07057375
- Testing
- Pulsed electromagnetic fields Thearpy
- Where
- Hong Kong
- Volunteers
- 110 people
- Sponsor
- Chinese University of Hong Kong
Prostate Cancer
To Identify Potential New Urine Markers for the Screening of Prostate Cancer
Prostate gland is a clinically important male sexual organ and its main function is for the production of semen. Globally, it is the second most common cancer in men globally and is also the fifth cancer cause for death in male.
- Trial name
- NCT03914391
- Where
- Hong Kong
- Volunteers
- 10,000 people
- Sponsor
- Chinese University of Hong Kong
Prostate Cancer
Hong Kong Prostate Cancer Study Group Database
Prostate cancer (PCa) is ranked 3rd in annual incidence of male cancer and ranked 5th for cancer-related death in men in Hong Kong which accounts for about 9.1 deaths per 100,000 men in 2011.
- Trial name
- NCT03344835
- Testing
- No intervention
- Where
- Hong Kong
- Volunteers
- 15,000 people
- Sponsor
- Chinese University of Hong Kong
Renal Stone
Robotic Flexible Ureteroscopy Versus Standard Flexible Ureteroscopy for Renal Stones
This is a prospective randomized clinical trial which aims to compare the clinical outcomes of robotic flexible ureteroscopy and standard flexible ureteroscopy for the treatment of renal stones.
- Trial name
- NCT06660914
- Testing
- Flexible Ureteroscopy
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
Depression Scale Score
Utilizing Embodied Artificial Intelligence (AI) for the Development of Digital Cognitive Behavioral Therapy (CBT) for Depression in Virtual Reality (VR)
Depression is a prevalent mental disorder characterized by pervasive low mood, diminished interest or pleasure, and a range of cognitive and physical symptoms.
- Trial name
- NCT07172113
- Testing
- CBT + VR
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
VHL - Von Hippel-Lindau Syndrome
Belzutifan VHL RCC HK Prospective Registry
This study aims to evaluate the Belzutifan's efficacy, drug safety, disease course, and the health-economic impact of the treatment to Von Hippel-Lindau (VHL) syndrome.
- Trial name
- NCT07554508
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
Thoracic Surgery
Thoracic Surgery by SHURUI Single-Port Surgical Robot
The introduction of single-port surgical robot has been a transformative breakthrough in the medical field, representing a significant advancement in minimally invasive procedures.
- Trial name
- NCT07255703
- Testing
- Device: Endoscopic Surgical System, SR-ENS-600
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Upper Gastrointestinal Bleeding
OTSC vs. Angiographic Embolization in Patients With Refractory Non-variceal Upper Gastrointestinal Bleeding
In the management of patients with acute upper non-variceal upper gastrointestinal bleeding, further bleeding is the most important adverse factor predictive of mortality.
- Trial name
- NCT04902248
- Testing
- The OTSC® System Set, angiographic embolization
- Where
- 5 sites in China, Hong Kong and 1 more
- Volunteers
- 236 people
- Sponsor
- Chinese University of Hong Kong
Renal Stone
Perioperative Parameter and Treatment Outcomes of ECIRS in Asia
This is an observational, international, multicenter, cohort study, prospectively collecting clinical data registry on consecutive patients with urinary stone undergoing ECIRS.
- Trial name
- NCT05894668
- Testing
- ECIRS
- Where
- 3 sites in Hong Kong
- Volunteers
- 1,000 people
- Sponsor
- Chinese University of Hong Kong