Clinical trials: open to volunteers, in Hong Kong
3-nil Buildings Seniors
Pilot Project on Enhancing Support for Hidden Elderly in the Three-nil Buildings and Old Tenement Buildings: Capacity Building & Impact Evaluation
The aims of this interventional study are of two-fold. First, the study aims to develop the capacity to facilitate the collaborating NGOs to address the social determinants of aging well for 3-N seniors.
- Trial name
- NCT07920328
- Testing
- Mapped intervention based on health status
- Where
- Hong Kong
- Volunteers
- 1,520 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Acute Heart Failure (AHF)
Comprehensive Clinical Prediction Rule for Acute Heart Failure
The goal of this prospective observational cohort study is to establish a comprehensive clinical prediction rule integrating clinical characteristics, point-of-care testing (POCT) of NT-proBNP, an 8-point LUS, and a rapid cardiac…
- Trial name
- NCT07754084
- Testing
- Acute Heart Failure Diagnostic Method
- Where
- 3 sites in Hong Kong
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mitral Valve Insufficiency
Multi-center Study of Three-Dimensional Transesophageal Echocardiography in Patients With Secondary Mitral Regurgitation
Three-dimensional transesophageal echocardiography (3D-TEE) enables detailed assessment of mitral valve anatomy, annular geometry, and regurgitation.
- Trial name
- SMR-3DTEE (NCT07918937)
- Testing
- Transthoracic and Three-Dimensional Transesophageal Echocardiography
- Where
- 93 sites in China, Hong Kong and 1 more
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- First Hospital of China Medical University
Behavior
A Chatbot to Reduce Chemsex and HIV-related Risk Behaviors Among Men Who Have Sex With Men
The goal of this clinical trial is to investigate whether receiving chatbot-delivered stage-of-change-tailored online interventions is effective in reducing chemsex among men who have sex with men in Hong Kong.
- Trial name
- NCT07472582
- Testing
- Chatbot-delivered online interventions and online videos, Online videos only
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Dementia Caregiver
The Existential Cognitive Intervention to Enhance Positive Aspect of Caregiving (EXCITE-PAC) in a Dementia Context
Research evidence is emerging on the co-existence of a positive caregiving experience in the physically and psychosocially taxing dementia care context, but little attention has been paid to promoting the positive aspects of…
- Trial name
- EXCITE-PAC (NCT07396298)
- Testing
- Existential-cognitive intervention to enhance PAC, Usual care
- Where
- Hong Kong
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Sleep Disturbance, Emotional Disturbance
Pilot Trial for Health Products on Mood and Sleep Quality
This is a pilot, single-site clinical trial that will follow a randomized, double-blinded, parallel-group, placebo-controlled design.
- Trial name
- NCT06579183
- Testing
- Vita Calm Mood Booster Formula (VCMBF), Vita Calm Deep Sleep Formula (VCDSF)
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Prostate Cancer
Artificial Intelligence (AI)-Assisted Risk-based Prostate Cancer Detection
This is a prospective clinical study recruiting 510 men at risk of PCa to undergo urine, blood, AI-assisted ultrasound and AI-assisted MRI investigations to stratify risk of clinically significant PCa (csPCa).
- Trial name
- NCT05443412
- Testing
- Diagnostic test for prostate cancer
- Where
- Hong Kong
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Atherosclerosis Cardiovascular Disease
Isometric Resistance Exercise on Accelerated Atherosclerosis in Hypertension
Background: Hypertension (HT) is the most common condition worldwide, predisposing to atherosclerotic disease. However, most HT patients have suboptimal BP control despite anti-HT medications.
- Trial name
- IRE-HT (NCT07665034)
- Testing
- Squatting Exercise, Stretching (Yoga) Exercise
- Where
- Hong Kong
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Pancreatic Steatosis, Pancreatic Cyst
Determination of Pancreatic Steatosis Prevalence and Correlation With High-risk Cyst Features
Pancreatic cancer is the fifth leading cause of cancer mortality in Hong Kong and the seventh leading cause of cancer mortality worldwide. In 2020, approximately 496000 new cases of pancreatic cancers were diagnosed globally .
- Trial name
- FPPCN (NCT05334836)
- Testing
- MRI for pancreatic fat and liver fat quantitation
- Where
- Hong Kong
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Fertility Awareness, Ovarian Reserve
Improving Women's Fertility Awareness and Reducing Anxiety Through Ovarian Reserve Screening and AI Counseling
This study evaluates the impact of preventive ovarian reserve screening and artificial intelligence (AI)-enabled counseling on fertility awareness and reproductive anxiety among women in Hong Kong.
- Conditions
- Fertility Awareness, Ovarian Reserve, Family Planning
- Trial name
- NCT07894302
- Testing
- AI-Enabled Fertility Counseling, Standard Educational Materials or PDF laboratory reports
- Where
- Hong Kong
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- City University of Hong Kong
Aortic Dissection
Potential Diagnostic Biomarkers for Aortic Dissection in the Emergency Department
The goal of this observational study is to determine the utility of desmosine, D-dimer and aggrecan as early diagnostic biomarkers in aortic dissection.
- Trial name
- ADD-ED (NCT06065306)
- Where
- Hong Kong
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
PARKINSON DISEASE (Disorder)
Oculomotor-Pupillary AI Biomarkers in Parkinson's
The goal of this prospective observational study is to investigate whether oculomotor-pupillary abnormalities detected using a novel edge-AI eye-tracking device can serve as objective and quantitative biomarkers for the early…
- Trial name
- NCT07886450
- Testing
- Edge-AI Eye-Tracking Assessment
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Obstructive Sleep Apnea
Microbiome and Metabolomics Profiling in Children With OSA
Objectives: Obstructive sleep apnoea (OSA) exhibits variable susceptibility to end-organ morbidities. Previous studies suggest that physiological sequelae in individuals with OSA promote changes in microbiome, which also interact…
- Trial name
- NCT06452992
- Where
- Hong Kong
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Dementia Caregiver
Machine Learning Enabled Management of Behavioural and Psychological Symptoms of Dementia Intervention for Dementia Caregivers
Develop and test a machine learning enabled management of behavioural and psychological symptoms of dementia intervention for dementia caregivers.
- Trial name
- NCT07444866
- Testing
- Active Control, Behavioral: Continue, Behavioral: Enhance human coaching
- Where
- Hong Kong
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Education University of Hong Kong
Psychological Well-being, Gratitude
Effects of School-Based Ignatian Examen Meditation on Well-Being, Gratitude, Hope, and Spirituality in Hong Kong Catholic Primary School Students
This study aims to investigate the effects of Ignatian Examen Meditation on students' psychological well-being, gratitude, hope, and spirituality.
- Conditions
- Psychological Well-being, Gratitude, Hope, Spirituality
- Trial name
- NCT07857980
- Testing
- Examen Meditation
- Where
- Hong Kong
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Resilience
Partial Digitalization of Mission ReST
The goal of this non-randomized trial is to partially digitalize and develop a web-based resilience-building intervention and pilot-test its feasibility, acceptability, and appropriateness in an undergraduate sample over a…
- Trial name
- NCT07851792
- Testing
- Digitalized Session 1 of Mission ReST, In-person delivery of Mission ReST Session 1
- Where
- Hong Kong
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Chronic Hepatitis B Virus Infection
A Study on IB-001 Dose Response and Tolerability in Healthy Adults and Those With Chronic Hepatitis B
This study will examine the safety and tolerability of single and multiple doses of IB-001 in two parts: Part A: SAD study in approximately 50 Healthy Volunteers (HV).
- Trial name
- NCT07389044
- Testing
- IB-001, Peginterferon Alfa-2A
- Where
- 5 sites in Hong Kong, Moldova and 2 more
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- IntegerBio
To Evaluate the Efficacy and Safety of Selected TCM Elbow Manipulation in Treating, Lateral Epicondylitis
Efficacy and Safety of Selected Traditional Chinese Medicine Elbow Manipulation Versus Mill's Manipulation as Control for Lateral Epicondylitis
Background: Lateral epicondylitis (LE), also referred to as lateral elbow tendinopathy and tennis elbow, is commonly seen clinically as an orthopedic disease.
- Trial name
- NCT07843771
- Testing
- Selected Traditional Chinese Medicine manipulation, Mill's Manipulation
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Insomnia, Healthy Adult
The Impact of Acute Pain on Sleep Parameters in the Insomnia Population and Healthy Controls
This study investigates how acute exercise-induced muscular pain affects sleep quality and sleep architecture in people with insomnia compared to healthy sleepers.
- Conditions
- Insomnia, Healthy Adult, Sleep, Musculoskeletal Pain
- Trial name
- NCT07826650
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Insomnia, Healthy Adult
The Impact of Insomnia on Pain Sensitivity and the Trajectory of Exercise-induced Muscular Pain
Sleep is a critical determinant of physiological recovery and pain regulation. Growing evidence suggests that sleep disruption directly heightens central and peripheral pain sensitivity to sensory stimuli (e.g., mechanical…
- Conditions
- Insomnia, Healthy Adult, Musculoskeletal Pain, Pain Sensitivity
- Trial name
- NCT07827664
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University