Clinical trials: in Chile
Ulcerative Colitis (UC)
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
The Phase 1 study described herein will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of XmAb942 in healthy volunteers (Parts A and B).
- Trial name
- NCT06619990
- Testing
- XmAb942
- Where
- 114 sites in United States, Argentina and 17 more
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Xencor, Inc.
Pneumococcal Infections, Immunization Programs
Randomized Controlled Trial Of Text Messages To Increase Pneumococcal Vaccination In Adults In Chile.
The goal of this randomized controlled trial is to learn if text message reminders sent through WhatsApp increase pneumococcal vaccination coverage in adults turning 65 years old in Chile.
- Conditions
- Pneumococcal Infections, Immunization Programs, Vaccination Coverage, Text Messaging (Intervention)
- Trial name
- PNEUMO-SMS (NCT07659470)
- Testing
- WhatsApp text message reminder for pneumococcal vaccination
- Where
- Chile
- Volunteers
- 40,753 people, healthy volunteers welcome
- Sponsor
- Pablo Tomás Valenzuela García
Stress, Psychological, Anxiety Disorders
Acceptability and Feasibility of an 8-week Online Mindfulness-Based Cognitive Therapy Program Among Undergraduate Students
Mental health problems -particularly depression- are the main cause of morbidity in young people (1), which has a known association with different health and social problems, such as increased alcohol consumption and drug…
- Conditions
- Stress, Psychological, Anxiety Disorders, Depression, Unipolar
- Trial name
- NCT05114824
- Testing
- Mindfulness-Based Cognitive Therapy
- Where
- Chile
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Suicidal Ideation, Depression Disorders
Acceptability and Feasibility of Reframe-IT+U for Suicidality in University Students.
Mental health in university students is a growing concern worldwide. In Chile, previous studies have shown high rates of depressive symptoms, anxiety, and suicidal risk in this population.
- Conditions
- Suicidal Ideation, Depression Disorders, Anxiety
- Trial name
- Reframe-IT+U (NCT07001202)
- Testing
- Indicated Prevention for suicidality
- Where
- Chile
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Depression/Anxiety
Acceptability and Feasibility of a Universal Preventive Intervention
Mental health in the university population has become a common and serious problem within university institutions worldwide in recent years.
- Trial name
- FDI2024 (NCT06419868)
- Testing
- "Universal preventive intervention for depression and anxiety for university students"
- Where
- Chile
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Obese or Overweight Healthy Volunteers, Type 2 Diabetes Mellitus (T2DM)
A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM
The purpose of this study is to: evaluate the safety and tolerability of single ascending doses of ALN-4324 in healthy volunteers and to characterize the single-dose PK of ALN-4324 evaluate the efficacy, safety, tolerability, PK…
- Trial name
- NCT06845202
- Testing
- ALN-4324
- Where
- 22 sites in United States, Argentina and 4 more
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Alnylam Pharmaceuticals
Depression/Anxiety
Acceptability and Feasibility of an In-person 8-week Mindfulness-Based Cognitive Therapy Program Among Undergraduates
Mental health among university students has emerged as a significant global issue. Recent meta-analyses reveal that 25% of students experience depressive symptoms and 14% exhibit suicidal behaviors.
- Trial name
- MFS (NCT06757842)
- Testing
- Mindfulness in Students
- Where
- Chile
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Breast Screening
Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer
This randomized phase III trial studies digital tomosynthesis mammography and digital mammography in screening patients for breast cancer.
- Trial name
- NCT03233191
- Testing
- Digital Mammography, Digital Tomosynthesis Mammography, Laboratory Biomarker Analysis
- Where
- 149 sites in United States, Argentina and 9 more
- Volunteers
- 108,508 people, healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group
Socioemotional Development, Physical Activity
Newenkantun: a Play-based Program to Promote Socioemotional Learning in Early Childhood Education in Chile.
What is this study about? This study will test a program called "Newenkantun" (which refers to a hand-strength game in Mapuche culture) designed to help young children develop important social and emotional skills through play…
- Conditions
- Socioemotional Development, Physical Activity, Sleep, Motor Skills
- Trial name
- Newenkantun (NCT07871929)
- Testing
- Teacher Professional Development, Parent/guardian support, Play-Based Activities and Environmental Modifications
- Where
- 2 sites in Chile
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Fibromyalgia, Fibromyalgia (FM)
Feasibility and Preliminary Effects of an Asynchronous Microlearning Intervention on Fibromyalgia Knowledge Among Primary Health Care Workers
This randomized controlled pilot trial will evaluate the feasibility and preliminary effects of an asynchronous microlearning intervention on fibromyalgia knowledge among Primary Health Care workers.
- Conditions
- Fibromyalgia, Fibromyalgia (FM), Fibromyalgia Syndrome
- Trial name
- FIBROK-PILOT (NCT07865767)
- Testing
- Written Educational Material on Fibromyalgia, Asynchronous Microlearning Intervention on Fibromyalgia
- Where
- Chile
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Instituto Neurociencia Del Dolor
Skin Ageing, Skin
Skin Type Determination Using Image Artificial Intelligence
Skin color, how easily a person burns or tans in the sun (skin phototype), and the amount of chronic sun damage in the skin are important factors in skin health.
- Trial name
- SPAI (NCT07765303)
- Testing
- Skin imaging and skin characteristic assessment
- Where
- 13 sites in Australia, Brazil and 9 more
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Region Skane
Circadian Rhythm Disruption, Healthy Volunteers
Cronobióticos Naturales
Brief Summary The goal of this clinical trial is to learn if a drink made from native berries of southern Chile can change the body's natural production of melatonin (a hormone that helps control sleep), sleep quality, and some…
- Trial name
- ChronoNaturals (NCT07848464)
- Testing
- Chronobiotic
- Where
- Chile
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad San Sebastián
Physical Activity
Efficacy of a Training Program in Adults Following a Vegan Diet Versus an Omnivorous Diet
The study consisted of a non-randomized controlled clinical trial with measurements at baseline and at the end of a 16 week intervention.
- Trial name
- Vegan (NCT06423209)
- Testing
- Strength training program
- Where
- Chile
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Universidad de Concepcion
Dental Caries; Oral Health; Malocclusion
Dental Caries and Related Factors in 6-Year-Old Schoolchildren in Chile: National Evidence for Assessment and Decision-Making (6yOH-Chile)
Dental caries is the most prevalent chronic non-communicable disease in childhood worldwide. In Chile, the last nationally representative oral health survey was conducted in 2007 and reported a caries experience prevalence of…
- Trial name
- 6yOH-Chile (NCT07863947)
- Where
- Chile
- Volunteers
- 2,484 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
HIV-1 Infection
DOR/ISL in HIV-1 Antiretroviral Treatment-naïve Participants (MK-8591A-053)
This is a randomized, active-controlled, double-blind clinical study designed to evaluate the antiretroviral activity, safety, and tolerability of doravirine/islatravir (DOR/ISL [MK-8591A]) in treatment-naïve participants with…
- Trial name
- NCT05705349
- Testing
- DOR/ISL, BIC/FTC/TAF
- Where
- 131 sites in United States, Argentina and 19 more
- Volunteers
- 537 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Clinical Competence
Augmented Reality Training for Pelvic Exams and Pap Smears in Medical Students
This randomized controlled trial evaluated whether augmented reality (AR)-based pre-simulation training improves the acquisition of speculum examination and Papanicolaou (Pap) smear sampling competencies among undergraduate…
- Trial name
- ARTES (NCT07852078)
- Testing
- Augmented Reality (AR)-Based Training, Conventional Text- and Video-Based Training
- Where
- Chile
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Atopic Dermatitis
Retention of Vernix Caseosa in Newborns for Primary Prevention of Atopic Dermatitis
Atopic dermatitis (AD), also known as eczema, is a common chronic inflammatory skin disease that usually begins in infancy and causes significant itching, discomfort, and sleep disturbance.
- Trial name
- PROTEGO (NCT07333378)
- Testing
- Retention of Vernix Caseosa After Birth, Removal of Vernix Caseosa After Birth
- Where
- 2 sites in Chile
- Volunteers
- 1,383 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Respiratory Syncytial Virus
A Study to Evaluate the Safety and Efficacy of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus (RSV) in Adults ≥60 Years of Age
The main purpose of Part A of this study is to evaluate the safety and tolerability of mRNA-1345 vaccine and to demonstrate the efficacy of a single dose of mRNA-1345 vaccine in the prevention of a first episode of RSV-associated…
- Trial name
- NCT05127434
- Testing
- mRNA-1345
- Where
- 269 sites in United States, Argentina and 21 more
- Volunteers
- 36,814 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Postural Balance, Aging
Immediate Effects of Vojta Therapy on Postural Control in Older Adults
This exploratory randomized assessor-blinded study aimed to determine whether a single session of Reflex Locomotion Therapy according to Vojta produces immediate changes in postural control in community-dwelling older adults…
- Conditions
- Postural Balance, Aging, Frailty
- Trial name
- VOJTABALANCE (NCT07829172)
- Testing
- Reflex Locomotion Therapy according to Vojta, Educational Session
- Where
- Chile
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Marianela Alejandra Valenzuela Sandoval
Human Immunodeficiency Virus (HIV), HIV Pre-Exposure Prophylaxis
A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)
Researchers are looking for new medicines to prevent HIV-1 (Human Immunodeficiency Virus Type 1) infection. The goals of this study are to learn: If taking MK-8527 once a month works to prevent HIV-1 infection as well as or…
- Trial name
- NCT07044297
- Testing
- MK-8527, FTC/TDF
- Where
- 81 sites in United States, Argentina and 14 more
- Volunteers
- 4,390 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC