Clinical trials: in Côte d’Ivoire
COVID-19
Variants of SARS-CoV-2 Causing COVID-19 in Africa
The main objective of this research is to identify and characterize the different molecular variants of SARS-CoV-2, emerging and / or circulating in several countries of Sub-Saharan Africa (Burkina Faso, Côte d'Ivoire, Gabon…
- Trial name
- South-Spike (NCT05311891)
- Testing
- RT PCR
- Where
- 6 sites in Burkina Faso, Chad and 4 more
- Volunteers
- 12,600 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Older Adults
Frailty, Geriatric Syndromes and Care Pathways of Older Adults Living With HIV in West Africa
With currently available antiretroviral therapy, people living with HIV (PLWHIV) are living longer. This exposure to HIV and combination antiretroviral therapy may accelerate the aging of this population, thus increasing the…
- Trial name
- NCT07355413
- Where
- 6 sites in Burkina Faso, Côte d’Ivoire and 1 more
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Malaria, Anemia
Perennial Malaria Chemoprevention (PMC) in Côte d'Ivoire
The Plus Project will assess the impact, operational feasibility, efficacy, effectiveness, and cost-effectiveness of PMC. Specifically, the impact evaluation will involve monitoring a passive cohort of all children in the study…
- Trial name
- NCT05856357
- Testing
- Sulfadoxine pyrimethamine
- Where
- Côte d’Ivoire
- Volunteers
- 1,381 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Health Education, Health Communication
Evaluation of "C'Est La Vie!" Digital Health Education
The University of California, Los Angeles (UCLA) will lead the online evaluation of four digital health campaigns developed by a non-governmental organization (NGO), Réseau Africain de l'Éducation pour la Santé (RAES), or African…
- Trial name
- NCT07636629
- Testing
- Evaluating how to deliver messages to young people online
- Where
- 3 sites in Burkina Faso, Côte d’Ivoire and 1 more
- Volunteers
- 492 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV/AIDS
Access to PrEP for MSM: Acceptability and Feasibility in Community-based Clinics in West Africa (CohMSM-PrEP)
This demonstration project will assess the acceptability and feasibility of pre-exposure prophylaxis (PrEP) for men who have sex with men (MSM) as part of a comprehensive HIV prevention package in community-based clinics in West…
- Trial name
- CohMSM-PrEP (NCT03459157)
- Testing
- HIV prevention package including PrEP
- Where
- 4 sites in Burkina Faso, Côte d’Ivoire and 2 more
- Volunteers
- 649 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV Infection
Feasibility and Interest of a HIV Quarterly Preventive Global Care in Men Who Have Sex With Men in Sub-Saharan Africa
The objective of the study is to evaluate the feasibility and interest of a HIV quarterly preventive global care for men who have sex with men (MSM) in sub-Saharan Africa to help reducing HIV incidence in this key population…
- Trial name
- CohMSM (NCT02626286)
- Testing
- HIV quarterly global care
- Where
- 4 sites in Burkina Faso, Côte d’Ivoire and 2 more
- Volunteers
- 885 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Malaria
Net Transition Initiative: Efficacy of Two Next-generation Nets for Control of Malaria in Cote d'Ivoire
The investigator plan to conduct a three-arm cluster-randomized control trial which compares two next generation of long-lasting Insecticidal Nets (LLINs); Veeralin®LLIN (PBO-py LLIN), Interceptor G2 (chlorfenapyr-py LLIN) to a…
- Trial name
- NCT05796193
- Testing
- Alpha-cypermethrin and PBO LLIN, Alpha-cypermethrin and Clorfenapyr LLIN, Alpha-cypermethrin only LLIN
- Where
- Côte d’Ivoire
- Volunteers
- 1,650 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Onchocerciasis
Safety of a Single Dose of Moxidectin Compared With Ivermectin in Individuals Living in Onchocerciasis Endemic Areas and in Individuals Living in Onchocerciasis Endemic Areas With High Levels of Lymphatic Filariasis Co-endemicity Receiving Concomitant Albendazole
The purpose of this phase 3b study is to determine the safety of a single dose of moxidectin, compared to a single dose of ivermectin, in individuals living in onchocerciasis endemic areas and in individuals living in…
- Trial name
- NCT04311671
- Testing
- Moxidectin, Ivermectin, Albendazole
- Where
- 2 sites in Côte d’Ivoire, Democratic Republic of the Congo
- Volunteers
- 12,979 people, healthy volunteers welcome
- Sponsor
- Medicines Development for Global Health
Iron Deficiencies
A Study to Collect Data to Build Artificial Intelligence Derived Algorithms for Estimating Risk of Iron Deficiency and Anaemia in African Children
An exploratory study to collect data to build artificial intelligence derived algorithms for estimating iron status in African children
- Trial name
- FERROUS 3 (NCT07186205)
- Testing
- Standard blood test, Imaging and videography of anatomical sites
- Where
- 3 sites in Côte d’Ivoire
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Danone Asia Pacific Holdings Pte, Ltd.
Multiplex Testing of HIV, HBV, HCV and Syphilis, HIV
Clinical Performance Evaluation of MagIA IVD-MD Multiplex Testing (HIV/HBV/HCV/Syphilis)
Performance study to evaluate the clinical performance of the In-Vitro Diagnostics Medical Device MagIA H3S (a Multiplex Point-of-Care test for the combined detection of Human Immunodeficiency Virus (HIV), Hepatitis B and C and…
- Conditions
- Multiplex Testing of HIV, HBV, HCV and Syphilis, HIV, HBV, HCV
- Trial name
- MAGICS IBCS (NCT07170748)
- Where
- 2 sites in Côte d’Ivoire, Kenya
- Volunteers
- 2,950 people, healthy volunteers welcome
- Sponsor
- MagIA Diagnostics
Lymphatic Filariasis
Moxidectin for LF, Cote d'Ivoire (DOLF)
The purpose of this study is to determine whether moxidectin (Mox) will be more effective than ivermectin (IVM) when used in single-dose combination therapies for lymphatic filariasis (LF).
- Trial name
- NCT04410406
- Testing
- Ivermectin, Diethylcarbamazine, Albendazole
- Where
- Côte d’Ivoire
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Schistosomiasis
Introduction of Arpraziquantel Treatment for Schistosomiasis Control in Preschool-aged Children in Endemic Areas: A Small-scale Public Health Intervention Study
The proposed small-scale pilot studies are public health intervention studies implemented through established routine programs and services in the frame of the mass drug administration (MDA) campaigns in Côte d'Ivoire, Kenya and…
- Trial name
- ADOPTpilot (NCT06698510)
- Testing
- Arpraziquantel 150mg dispersible tablet
- Where
- 7 sites in Côte d’Ivoire, Kenya and 1 more
- Volunteers
- 18,500 people, healthy volunteers welcome
- Sponsor
- Peter Steinmann
Cervical Cancer
SUCCESS - Feasibility of HPV Testing and Treatment of Pre-cancerous Cervical Cancer Lesions (HPV Study)
The goal is to assess the feasibility and acceptability of integrating into existing health systems, provision of HPV screening and treatment of pre-cancerous cervical cancer lesions with ablative treatments in Burkina Faso, Côte…
- Trial name
- HPV (NCT05133661)
- Testing
- HPV testing
- Where
- 4 sites in Burkina Faso, Côte d’Ivoire and 2 more
- Volunteers
- 17,602 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Malaria,Falciparum, Morality
An Observational Study to Assess Effectiveness and Safety of The R21/Matrix-M Malaria Vaccine
This is an observational case-control study to assess the effectiveness of the R21/Matrix-M vaccine against severe malaria, clinical malaria (in high transmission perennial areas), and to assess if the R21 vaccine recipients are…
- Trial name
- NCT07009847
- Testing
- Case control study of clinical malaria, Case control study of severe malaria, Case control study of death (all cause)
- Where
- 5 sites in Burkina Faso, Côte d’Ivoire and 2 more
- Volunteers
- 2,308 people, healthy volunteers welcome
- Sponsor
- Serum Institute of India Pvt. Ltd.
Integrated Care, HPV Vaccination
Integrated HPV Vaccination and Adolescent Health in Ivory Coast
Background: Cervical cancer is a serious global public health problem, particularly in sub-Saharan Africa, where it is the leading cause of cancer in women, with around 70,722 new cases each year.
- Conditions
- Integrated Care, HPV Vaccination, Adolescent
- Trial name
- SHARP-CI (NCT06997705)
- Testing
- Optimized VMS
- Where
- Côte d’Ivoire
- Volunteers
- 3,384 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Malaria
EaveTubes for Vector Control
The goal of this clinical trial is to test whether In2Care EaveTubes (ETs) as a stand-alone tool can reduce malaria in an area where transmission is driven by insecticide-resistant Anopheles gambiae.
- Trial name
- NCT05736679
- Testing
- In2Care EaveTube
- Where
- Côte d’Ivoire
- Volunteers
- 1,870 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Malaria
MaCRA Part B in Côte d'Ivoire
This study aims to evaluate the effectiveness of monthly malaria rapid diagnostic test (RDT) validation meetings at district level on reducing the proportion of RDT results recorded as positive in health facility registers in…
- Trial name
- NCT06804902
- Testing
- Monthly RDT Validation Meeting
- Where
- Côte d’Ivoire
- Volunteers
- healthy volunteers welcome
- Sponsor
- PATH
Child Mortality
REACH2: Implementation Research on Bi-Annual Mass Distribution of Azithromycin to Children 1-11 Months in Côte d'Ivoire
REACH2 is a three-year implementation research study designed to examine the implementation through a mass drug administration platform of bi-annual single-dose azithromycin to reduce child mortality among children ages 1 to 11…
- Trial name
- REACH (NCT05016895)
- Testing
- Single-dose azithromycin
- Where
- Côte d’Ivoire
- Volunteers
- 767,535 people, healthy volunteers welcome
- Sponsor
- FHI 360
Dengue
Citizen Action for Sustainable Dengue Control in Sub-Saharan Africa
This project focuses on addressing arboviral outbreaks in Ivory Coast by involving local communities in the sustainable control of Aedes mosquitoes, utilizing scientific advice and environmental interventions.
- Trial name
- NCT06648603
- Testing
- Community-based larval source management, Enhanced Aedes adults trapping (BG-GAT), Community-based larval source management with Enhanced Aedes adults trapping (BG-GAT)
- Where
- Côte d’Ivoire
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Malaria
Insecticide Resistance Management in Burkina Faso and Côte D'Ivoire
This study evaluates the benefit to use 1) insecticide residual sprayings, 2) larvicides, 3) Ivermectin for domestic animals and 4) behaviour change communication strategy to complement the universal coverage with LLINs through a…
- Trial name
- REACT (NCT03074435)
- Testing
- Indoor residual sprayings, Larvicide, BCC
- Where
- 2 sites in Burkina Faso, Côte d’Ivoire
- Volunteers
- 15,776 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche pour le Developpement