Clinical trials: fMRI
Cannabis Dependence
Neural Indices Associated With Relapse in Cannabis Dependence
The aim of this fMRI study is to investigate neural indices of relapse in cannabis dependence. The development and maintenance of drug addictions have been associated with deficits in cognitive control, craving and impaired…
- Trial name
- NCT02801422
- Testing
- fMRI
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Phantom Limb Pain
Phantom Limb Pain Triggered by Micturition
Phantom Limb Pain ( PLP) is pain that is perceived and referred to a region of the body that is no longer present. in most patients, severity and frequency of phantom pain attacks gradually decrease over several weeks to 2 years…
- Trial name
- NCT03855930
- Testing
- functional MRI
- Where
- 2 sites in Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loewenstein Hospital
Structural Racism, Substance Use Risk
Structural Racism, Reward Related Decision Making and Substance Use Risk
The goal of this observational study, which has a pilot phase (R61) and a second, larger phase (R33), is to learn about the impact of indicators of structural racism (SR) on substance use risk in Puerto Rican adolescents living…
- Trial name
- NCT06221839
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Columbia University
Psychosis, Schizophrenia
Effects of Aripiprazole and Haloperidol on Mesolimbic System Functioning
The main objective is to investigate if the brain activation signature of a typical antipsychotic agent is dissociable from a newer drug with a pharmacological profile that differs from both typical and atypical antipsychotics…
- Trial name
- Arip_200901 (NCT01161277)
- Testing
- Aripiprazole, Haloperidol
- Where
- Norway
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
ADHD, Attention Deficit Hyperactivity Disorder
Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk
The study team will examine the effects of FDA approved stimulant and non-stimulant medications for ADHD, among youth with ADHD and with and without Oppositional Defiant Disorder (ODD) or Conduct Disorder (CD), on reward systems…
- Trial name
- MPH-ATX (NCT03781765)
- Testing
- Methylphenidate, Atomoxetine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Frovatriptan, Menstrual Migraine
Frovatriptan and Menstrual Migraine
We are looking for women who suffer from menstrual migraine to participate in a 2-visit migraine brain imaging research study. Our goal is to see how the menstrual migraine brain's pain pathways function when the migraineur has…
- Trial name
- FROVA (NCT01114711)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Mclean Hospital
Smoking
fMRI of Stress in Smoking Behavior
To examine the influence of current daily tobacco smoking on brain activation during stress, tobacco cue, and neutral relaxing conditions
- Trial name
- NCT01719471
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Prostate Cancer
Functional Magnetic Resonance Imaging for High Throughput Curietherapy Planning in Prostate Cancer
Merge the data of ultrasound with that of the anatomical and functional MRI is necessary since the high dose rate Curietherapy is carried out under ultrasound guidance.
- Trial name
- FIBROP (NCT02516995)
- Testing
- Functional magnetic resonance imaging, Ultrasound
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Concussion, Mild, Post-Concussion Symptoms
Effects of Bright Light Therapy in Mild Traumatic Brain Injury
Mild traumatic brain injuries (mTBI) or "concussions" are an increasingly prevalent injury in our society. Patients with post-concussion syndrome have been shown to have deficits on tests of short term memory, divided attention…
- Conditions
- Concussion, Mild, Post-Concussion Symptoms, Sleep Problems
- Trial name
- NCT01747811
- Testing
- wavelength-1 bright light, wavelength-2 bright light
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Parkinson's Disease
Optimization of fMRI for the Study of Basal Ganglia Activation in Parkinson's Disease
Functional magnetic resonance imaging (fMRI) is a non-invasive imaging technique assessing neuronal activations during motor or cognitive tasks.
- Trial name
- 2010-A01115-34 (NCT01429909)
- Testing
- MAGNETOM Avanto (MRI device)
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Loneliness
Oxytocin-augmented Cognitive-behavioral Group-based Short-term Intervention for Loneliness
The purpose of this study is to evaluate the clinical potential of oxytocin (OT) as an adjunct to a cognitive-behavioral group-based shortterm intervention for participants suffering from loneliness.
- Trial name
- NCT04137432
- Testing
- Oxytocin nasal spray
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Chronic Low Back Pain (CLBP), Acute Low Back Pain
Multimodal Imaging and Biospecimen Collection for Low Back Pain (LBPB)
This prospective cohort study investigates the neurobiological, genetic, and psychosocial mechanisms underlying acute and chronic low back pain (LBP).
- Conditions
- Chronic Low Back Pain (CLBP), Acute Low Back Pain, Low Back Pain, Chronic Pain
- Trial name
- LBPB (NCT06967363)
- Testing
- Nerve Block, endoscopic spinal disecetomy, Medication
- Where
- 2 sites in China
- Volunteers
- 360 people
- Sponsor
- Peking University Third Hospital
Dementia of the Alzheimer Type
Effect of Cognitive Intervention in Alzheimer's Disease (AD) on Functional Cortical Networks in fMRI
The study aims to detect the effect of a structured cognitive rehabilitation program, teh stage specific intervention STACog, on cognitive performance and functional activation in fMRI in a group of patients with mild cognitive…
- Trial name
- ECIF (NCT01329601)
- Testing
- StaCog, stage specific cognitive Intervention, booklet based training
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University of Rostock
Dyslexia, Developmental, Reading
Enhancing Letter-Speech Sound Learning and Reading Network Activation With Transcranial Electrical Stimulation
This study investigates the effects of transcranial electrical stimulation (tES) on the brain and its potential to enhance reading-related learning.
- Conditions
- Dyslexia, Developmental, Reading, Dyslexia, Learning
- Trial name
- LexiStim (NCT07546292)
- Testing
- Transcranial random noise stimulation
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Silvia Brem
Posttraumatic Stress Disorder
Neuroeconomics of Social Behavior Following Trauma Exposure
This study will use a neuroeconomic paradigm with state-of-the-art imaging protocols to probe abnormal social reward processing underlying social withdrawal in symptomatic trauma-exposed women.
- Trial name
- NCT03383536
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Parkinson Disease, Neurologic Disorder
Effect of taVNS of Brainstem Activation in Early and Late Parkinson's Disease Patients - an fMRI Study
This is a randomised, within-subject, double-blinded, placebo-controlled study to assess the fMRI correlates of central nervous system (CNS) response to taVNS in early vs late-stage Parkinsons disease (PD), at two different…
- Trial name
- NCT05967598
- Testing
- Noninvasive transcutaneous auricular vagus nerve stimulation at 100Hz, Noninvasive transcutaneous auricular vagus nerve stimulation at 25Hz
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- University of Ljubljana
Healthy
The Functional Anatomy of Personality Trait Knowledge: An fMRI Study
This study will identify the regions of the brain that are involved in personality trait knowledge-that is, what a person knows about aspects of personality such as "generous," "honest," and others.
- Trial name
- NCT00095407
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Brain Injuries, Traumatic
Mild TBI Assessment & Rehabilitation
One of the most pressing concerns within the VA currently is the provision of interventions that address the cognitive as well as emotional problems faced by Veterans with mild TBI and comorbid conditions.
- Trial name
- MTAR (NCT02920788)
- Testing
- Goal-Oriented Attentional Self-Regulation (GOALS), Brain Health Education (BHE), fMRI
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- VA Office of Research and Development
Alzheimer Disease
Imaging of New Learning in Severe Alzheimer's Disease Patients
This research attempts to better understand the altered and preserved memory mechanisms in Alzheimer disease, particularly to better apprehend learning implicit memory processes, and give a scientific support to non-pharmalogical…
- Trial name
- INCAS (NCT01839422)
- Testing
- Memory assessment, Brain imaging examination MRI
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Healthy
Renal Functional Magnetic Resonance Imaging in Healthy Persons - Reproducibility and Impact of Stress
The main purpose of the study is to describe the applicability and reproducibility of functional MRI scans of the kidneys in healthy participants.
- Trial name
- NCT04656314
- Testing
- Functional MRI scan
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aarhus