Clinical trials: Zinc Deficiency
Hearing Loss, Noise-Induced, Tinnitus, Noise Induced
Improvement of Tinnitus After Oral Zinc on Patients With Noise-induced Hearing Loss
Twenty patients with tinnitus and a typical noise-induced hearing loss (NIHL) audiogram were included. Each subject underwent an otoscopic examination, distortion product otoacoustic emissions, tinnitus-match testing, Tinnitus…
- Conditions
- Hearing Loss, Noise-Induced, Tinnitus, Noise Induced, Zinc Deficiency
- Trial name
- NCT02951715
- Testing
- zinc gluconate
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Zinc Deficiency
Zinc Deficiency in Dilated Cardiomyopathy
The aim of this study is to detect effect of oral zinc supplementation in pediatric patients with dilated cardiomyopathy.
- Trial name
- NCT04860921
- Volunteers
- 50 people
- Sponsor
- Assiut University
Vitamin D Deficiency
The Effect of Combinatorial Nutritional Supplementation on Immune Function in Healthy Older Adults
Many older adults do not get enough zinc, vitamin C and vitamin D, and this can be related to decreased ability to fight infection.
- Trial name
- NCT02876315
- Testing
- Redoxon VI
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Zinc Deficiency, Inflammation
Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc
The objective of the current study is to test the overarching hypothesis that the beef nutritive matrix is uniquely suited to direct dietary zinc to cellular compartments for improved metabolic function, leading to a greater…
- Conditions
- Zinc Deficiency, Inflammation, Metabolic Diseases, Vascular Diseases
- Trial name
- NCT05236374
- Testing
- Beef protein
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
HIV Infection, Alcohol Use
Alcohol's Impact on Inflammatory Markers in HIV Disease - Russia ARCH Cohort
The purpose of this study is to assess the longitudinal association between alcohol consumption and biomarkers of microbial translocation (sCD14) and inflammation/altered coagulation (IL-6/D-dimer); to establish a cohort of…
- Trial name
- NCT01614626
- Where
- Russia
- Volunteers
- 351 people
- Sponsor
- Boston Medical Center
Zinc Deficiency, Growth; Stunting, Nutritional
The Efficacy of Zinc-biofortified Rice in Bangladeshi Children
To assess the efficacy of the zinc biofortified rice on plasma zinc concentrations in infants from a rural area of Bangladesh.
- Trial name
- ZARI (NCT03079583)
- Testing
- Intervention-group, Control-group
- Where
- 2 sites in Bangladesh, Switzerland
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Zinc Deficiency
Effects of Initiation and Discontinuation of Short Term Zinc Supplementation on Plasma Zinc Concentration
This is a double-blind, randomized controlled trial conducted in men 19-65 years of age who will receive daily zinc supplements (10 or 20 mg zinc/d as zinc sulfate) or placebo for 21 days.
- Trial name
- NCT00459485
- Testing
- zinc sulfate
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Human Immunodeficiency Virus (HIV)
Repeat Doses of SB-728mR-T After Cyclophosphamide Conditioning in HIV-Infected Subjects on HAART
The purpose of this study is to evaluate the safety and tolerability of repeat doses of T-cell immunotherapy (SB-728mR-T) following cyclophosphamide conditioning. CCR5 is a major co-receptor for HIV entry into T-cells.
- Trial name
- NCT02225665
- Testing
- SB-728mR-T, Cyclophosphamide
- Where
- 5 sites in United States
- Volunteers
- 8 people
- Sponsor
- Sangamo Therapeutics
Iron Deficiency, Zinc Deficiency
Effect of Iron/Zinc-Biofortified Pearl Millet on Growth and Immunity in Children Aged 12-18 Months in India
In this study, iron- and zinc-biofortified pearl millet will be fed to young children in Mumbai, Maharashtra, India over a period of nine months to measure iron status, growth and immune function in comparison to children…
- Trial name
- NCT02233764
- Testing
- FeZnPM, CtrlPM
- Where
- 3 sites in India
- Volunteers
- 223 people
- Sponsor
- Cornell University
Zinc Deficiency
A Novel Bio-marker of Zinc Status
Zinc deficiency is a widespread public health problem in developing countries. The true prevalence of this condition remains uncertain because of lack of a specific, sensitive and reliable biomarker for assessment of human zinc…
- Trial name
- NCT01062347
- Testing
- Zinc
- Where
- Bangladesh
- Volunteers
- healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Preterm Infant, Effect of Drugs
Zinc Supplementation In Very Low Birth Weight Infants-A Randomised Controlled Trial
Zinc (Zn) is a structural component of human body and is a crucial element for a wide variety of cascades that take place in almost all organ systems.
- Conditions
- Preterm Infant, Effect of Drugs, Zinc Deficiency Disease
- Trial name
- NCT05311540
- Testing
- Zinc Sulfate
- Where
- Turkey (Türkiye)
- Volunteers
- 195 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Iron-deficiency, Anemia
Non-invasive Diagnostics of Iron Deficiency in Surgical Patients by Measuring Zinc Protoporphyrin-IX
In approx. 40% of the incidences anemia is caused by iron deficiency (= ID). In turn, preoperative iron-deficiency anemia (= IDA) is associated with an increase in morbidity and mortality as well as with the need for a blood…
- Conditions
- Iron-deficiency, Anemia, Iron Deficiency Anemia
- Trial name
- NCT03071497
- Testing
- Non-invasive analysis of Zinc protoporphyrin
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Malnutrition
Optimal Amount of Zinc to Include in a Lipid-based Nutrient Supplement (LNS)
To assess zinc-related biochemical and functional responses among young Burkinabe children with a presumed high risk of zinc deficiency who receive micronutrient products containing different amounts of zinc, provided with or…
- Trial name
- NCT00944281
- Testing
- LNS-Zn5, LNS-Zn10, LNS-Zn0
- Where
- Burkina Faso
- Volunteers
- 3,220 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Autism Spectrum Disorder, Zinc Deficiency
Zinc-AA Supplementation During Pregnancy & Lactation to Assess Effects on ASD Prevalence in Offspring
Autism and associated entities, grouped under the Autism Spectrum Disorders (ASD) is the fastest growing intellectual disability in the world, statistics signal for a 1 to 3% prevalence on infants.
- Conditions
- Autism Spectrum Disorder, Zinc Deficiency, Pregnancy Related
- Trial name
- NCT04983667
- Testing
- Zn-AA
- Where
- Mexico
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Instituto Tecnologico y de Estudios Superiores de Monterey
Iron Deficiency, Vitamin A Deficiency
Nutritional Status and Bouillon Use in Northern Ghana
This pilot aims to generate data that are critical for informing the design of a planned, more detailed study to evaluate the effect of multiple micronutrient (MN)-fortified bouillon cube on biomarkers of nutrient status of women…
- Conditions
- Iron Deficiency, Vitamin A Deficiency, Vitamin B 12 Deficiency, Folate Deficiency
- Trial name
- NCT04632771
- Testing
- N/A (observational study)
- Where
- Ghana
- Volunteers
- 995 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
HIV Infection, HIV Infections
Phase 1 Dose Escalation Study of Autologous T-cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Patients
This research study is being carried out to study a new way to possibly treat HIV. This agent is called a "Zinc Finger Nuclease" or ZFN for short. ZFNs are proteins that can delete another protein named CCR5.
- Trial name
- NCT01044654
- Testing
- SB-728-T
- Where
- 9 sites in United States
- Volunteers
- 19 people
- Sponsor
- Sangamo Therapeutics
HIV Infections
CCR5-modified CD4+ T Cells for HIV Infection
A Comparative Study of Autologous CD4+ T Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728 versus ex vivo Expanded Unmodified Autologous CD4+ T Cells in Treated HIV-1 Infected Subjects
- Trial name
- TRAILBLAZER (NCT03666871)
- Testing
- SB-728-T, Expanded unmodified autologous CD4+ T cells
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
Anemia, Iron Deficiency
Effectiveness of Iron-Fortified Milk on Iron Status and Anemia in Young Children in Mexico
Iron deficiency and anemia in infants and young children impair neurodevelopment. Efficacious interventions for reducing the prevalences of iron deficiency and anemia, under controlled conditions, are available.
- Conditions
- Anemia, Iron Deficiency, Stunting
- Trial name
- NCT00508131
- Testing
- Whole Cows Milk
- Where
- Mexico
- Volunteers
- 798 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Vitamin A Deficiency, Iron-deficiency
Effect of Household Use of Multiple Micronutrient-fortified Bouillon on Micronutrient Status Among Women and Children in Two Districts in the Northern Region of Ghana
Background: Micronutrient (MN) deficiencies are severe and widespread in West Africa, particularly among young children and women of reproductive age.
- Conditions
- Vitamin A Deficiency, Iron-deficiency, Folate Deficiency, Vitamin B 12 Deficiency
- Trial name
- NCT05178407
- Testing
- Multiple micronutrient-fortified bouillon cube, Control bouillon cube (iodine-only)
- Where
- Ghana
- Volunteers
- 2,372 people
- Sponsor
- University of California, Davis
Zinc Deficiency
A Randomized, Double-Blind, Placebo Controlled Study of NPC-02 in Patients With Zinc Deficiency
The objective of this study is to evaluate efficacy and safety of NPC-02 in patients with Zinc Deficiency.
- Trial name
- NCT02337569
- Testing
- NPC-02
- Where
- Japan
- Volunteers
- 57 people
- Sponsor
- Nobelpharma