Clinical trials: Wrinkles
Parotid Gland Tumor, Facial and Neck Rhytides
Facial Nerve Monitoring During Parotid and Facial Surgery Using a Non-Invasive Patch
The goal of this study is to test if a non-invasive patch can safely monitor facial nerve activity in adults during parotid or facial surgery.
- Trial name
- NCT07523373
- Testing
- Non-invasive facial nerve monitoring patch
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Rhytides, Wrinkle
Safety and Efficacy of SofWave Treatment to Lift the Upper Lip and Improve the Peri-Oral Rhytids
Open-label, non-randomized, prospective, multi-center, self-controlled
- Trial name
- NCT06104514
- Testing
- Sofwave
- Where
- 6 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Skin Aging, Wrinkles
Poly-L-lactic Acid (PLLA) Injection for Neck Skin Laxity: A Pilot Study
Skin aging of the neck commonly leads to wrinkles and skin laxity due to the gradual loss of collagen and structural support in the skin.
- Trial name
- NCT07689344
- Testing
- Poly-L-Lactic Acid (Sculptra) injection
- Where
- Thailand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Institute of Dermatology, Thailand
Wrinkle
The Effects of a 3-Part Skin Care Regimen on Facial Wrinkles and Biophysical Attributes
The purpose of this study is to analyze various cosmetic endpoints, subjective assessments, and skin parameters such as hydration, transepidermal water loss, fine lines, and wrinkles with the use of a 3-part skin care regimen.
- Trial name
- NCT05698485
- Testing
- Cleansing Balm, Facial Serum, Moisturizer
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Facial Aging, Skin Aging
Hyaluronic Acid Crosslinking Clinical Study
This prospective observational case series aims to evaluate the clinical efficacy, safety, and patient satisfaction associated with hyaluronic acid dermal fillers with different degrees of divinyl sulfone (DVS) crosslinking.
- Conditions
- Facial Aging, Skin Aging, Facial Volume Loss, Facial Rhytides
- Trial name
- HACS (NCT07744464)
- Testing
- Hyaluronic Acid Dermal Fillers
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Antony de Paula Barbosa
Aging
The Effectiveness of Epidermal Growth Factor Serum in Improve Facial Skin Hydration, Elasticity, Pigmentation, and Wrinkles.
EGF is a polypeptide that promotes cell differentiation and collagen production while decreasing melanin production. This study is designed to study its effectiveness in improving the texture and appearance of facial skin after…
- Trial name
- NCT05724589
- Testing
- Epidermal Growth Factor
- Where
- Thailand
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Institute of Dermatology, Thailand
Atopic Dermatitis
Effect of Holly Mangrove Shower Gel in Atopic Dermatitis Patients
Atopic dermatitis is a chronic intermittent inflammatory skin disease. Currently, there are many cosmeceutical skin products in which their major action affects skin hydration and skin barrier function.
- Trial name
- NCT02178215
- Testing
- Holly Mangrove Shower Gel
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Wrinkle
Threads Insertion in Forehead Static Wrinkles
The main objective of this study is to analyze the efficacy and safety of PDO threads in correcting deep static wrinkles on the upper face.
- Trial name
- NCT06179082
- Testing
- Botox then threads, threads only
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Zagazig University
Photoaging
Photoaging Treatment With Imiquimod
Recently it was demonstrated that imiquimod in addition to exerting a repairing effect in pre malignant and malignant lesions caused by UV radiation it reverses histopathological changes associated with the photoaging skin.
- Trial name
- NCT01935310
- Testing
- Imiquimod
- Where
- Colombia
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- CES University
Laxity of Skin
Investigation of Radiofrequency Device for Treatment of Wrinkles and Rhytides
The purpose of this pilot research study is to collect information on the safety and effectiveness of an experimental device intended to be used to improve the appearance of the skin by reducing the visibility of wrinkles and by…
- Trial name
- NCT01279226
- Testing
- Auralevée device
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rocky Mountain Biosystems, Inc.
Facial Skin Wrinkles
Safety And Efficacy Investigation Of The Effects Of ClearLift Q-Switched Nd:Yag 1064nm Laser Module In The Treatment Of Facial Skin Wrinkles
Alma Lasers ClearLift is a fractional non-ablative Q-Switched laser, allowing practitioners to use the benefits of a high intensity QS laser for the treatment of aged skin.
- Trial name
- NCT06349096
- Testing
- Alma Harmony
- Where
- Albania
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Alma Lasers
Rhytides, Skin Texture Irregularities
Efficacy & Safety of hADM Skin Booster
The goal of this randomized, split-face, double-blinded clinical trial is to evaluate the efficacy and safety of Elravie Re2O (particulated human Acellular Dermal Matrix, phADM) as a skin booster compared with hyaluronic acid…
- Conditions
- Rhytides, Skin Texture Irregularities, Photoaged Facial Skin, Skin Lifting and Tightening
- Trial name
- NCT07155278
- Testing
- Elravie Re2O, Elravie Balance
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Wrinkle Severity Rating Scale(WSRS) Grade 3 (Moderate) or 4 (Severe) of Nasolabial Folds
Clinical Trial of YYD701-2 for Treatment of Nasolabial Folds
A multicenter, active-controlled, randomized, evaluator and subject blinded, split-face, comparative, non-inferiority, Medical device Clinical trial.
- Trial name
- NCT03170050
- Testing
- YYD701-2, Restylane Perlane Lidocaine
- Where
- 2 sites in South Korea
- Volunteers
- 107 people
- Sponsor
- Yooyoung Pharmaceutical Co., Ltd.
Moderate to Severe Glabellar Lines
A Study to Assess the Effectiveness and Safety of IPN10200 in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows
The purpose of this study is to assess the effectiveness and safety of Corabotase (also known as IPN10200) compared to placebo in the improvement of the appearance of moderate to severe glabellar lines in adult participants.
- Trial name
- LAURITE 1 (NCT07427797)
- Testing
- Corabotase
- Where
- 23 sites in United States, Canada
- Volunteers
- 309 people
- Sponsor
- Ipsen
Upper Facial Lines (Glabellar Lines, Forehead Lines, & Lateral Canthal Lines)
Efficacy and Safety of DaxibotulinumtoxinA (DAXI) for Injection for Treatment of Upper Facial Lines
This is a Phase 2, multicenter, open-label, single-arm study to evaluate the efficacy and safety of DaxibotulinumtoxinA for injection (DAXI for injection) in the treatment of Glabellar Lines (GL), Dynamic Forehead Lines (FHL)…
- Trial name
- NCT04259086
- Testing
- DaxibotulinumtoxinA for injection
- Where
- 8 sites in United States, Canada
- Volunteers
- 48 people
- Sponsor
- Revance Therapeutics, Inc.
Wrinkle, Rosacea
Evaluation of Cutera Excel V™ Laser With Green Genesis and Micro-Lens Array (MLA)Attachment
Evaluate the Cutera excel V™ Laser with Green Genesis and a Micro-Lens Array (MLA) Attachment
- Conditions
- Wrinkle, Rosacea, Scarring
- Trial name
- NCT03424304
- Testing
- Excel V™ Laser With Green Genesis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Glabellar Frown Lines
Xeomin Treatment of Glabellar Lines Using OLD Versus COLD
This is a blinded, randomized study in the US to compare the duration response of two different concentrations of Xeomin in healthy female subjects with moderate to severe dynamic glabellar lines on maximum frown.
- Trial name
- NCT05305768
- Testing
- IncobotulinumtoxinA
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Clinical Testing of Beverly Hills
Wrinkle
A Retrospective Review Evaluating the Matrix Pro Applicator for Treatment of Wrinkles
This is a retrospective chart review of data from the multi-site prospective clinical trial, "Functional Usability and Feasibility Testing of the Profound Matrix™ System (FUFT2002)" to evaluate the safety and efficacy of the…
- Trial name
- NCT06219278
- Testing
- Profound Matrix
- Where
- 2 sites in United States, Israel
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Skin Aging, Skin Wrinkling
Evaluation of Safety and Efficacy of Using Imagine™ Computerized Radiofrequency System for Skin Tightening
Skin aging is a multifactorial process involving the 3 layers of the skin: Epidermis, dermis and hypodermis. Skin aging process involves among others: skin roughness (epidermis), skin dyschromia (epidermis, dermis), wrinkles and…
- Trial name
- NCT00945685
- Testing
- Endymion Imagine™ System for Skin Tightening
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Endymion Medical Ltd
Acne Scars - Mixed Atrophic and Hypertrophic, Wrinkle
Fractional Radiofrequency for the Treatment and Reduction of Acne Scars and Wrinkles
The objective of this clinical study is to evaluate the efficacy of fractional RF for the treatment and reduction of acne scarring or facial wrinkles.
- Trial name
- NCT04057768
- Testing
- Venus Viva
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Venus Concept