Clinical trials: Wound of Knee
ACL - Anterior Cruciate Ligament Rupture
Bio ACL Reconstruction Amnion Collagen Matrix Wrap and Stem Cells
Collagen based -membrane derived from amniotic tissue can be used to help reestablish the natural synovial lining of the reconstructed ACL, in effect acting as both a barrier from the synovial fluid and as a scaffold to contain…
- Trial name
- BioACLRCT (NCT03294759)
- Testing
- Bio ACL, Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Andrews Research & Education Foundation
Total Knee Anthroplasty, Venous Insufficiency (Chronic)(Peripheral)
Impact of Chronic Venous Insufficiency on Outcomes After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is an effective treatment for end-stage knee osteoarthritis; however, postoperative complications-particularly wound healing problems-remain a significant concern.
- Conditions
- Total Knee Anthroplasty, Venous Insufficiency (Chronic)(Peripheral), Doppler Ultrasound Diagnosis
- Trial name
- VENOUS-TKA (NCT07577141)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- SB Istanbul Education and Research Hospital
Total Knee Anthroplasty, Postoperative Pain
Proximal Spread in Adductor Canal Block(ACB)
This prospective, randomized clinical study is designed to evaluate the effects of two different injection levels of adductor canal block (ACB) on the proximal spread of local anesthetic and clinical outcomes in patients…
- Trial name
- ACB (NCT07595471)
- Testing
- Comparison of Proximal Adductor Canal Block, Comparison True Distal Adductor Canal Block.
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ankara Etlik City Hospital
Injury of Anterior Cruciate Ligament
Comparison of Infiltration Analgesia With Femoral Nerve Block After Hamstrings Anterior Cruciate Ligament Reconstruction
Pain treatment after anterior cruciate ligament reconstruction - Comparison of infiltration analgesia with femoral nerve block after.
- Trial name
- NCT01260363
- Testing
- Femoral nerve block, Local infiltration analgesia
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
ACL-injury
Influence of Injury to the Kaplan Fibers in Adult and Pediatric Patients With ACL Injury
The goal of this [type of study: observational study] is to [detect concomitant KF and ALL injury in knees with ACL injury using MRI in both adult and pediatric patients and compare the effect of KF injury and multiple risk…
- Trial name
- NCT06002308
- Testing
- Age
- Where
- China
- Volunteers
- 540 people
- Sponsor
- Sichuan Province Orthopetic Hospital
Anterior Cruciate Ligament Injuries
Effect of Open Kinetic CKE Exercises With NES in Patients With Post-ACL Reconstruction Surgery
"Anterior cruciate ligament (ACL) reconstruction is a commonly performed surgical procedure for restoring knee stability in patients following ACL injuries.
- Trial name
- NCT06913543
- Testing
- Group 1 (Experimental Group - OKC + NMES), Group 2 (Control Group - OKC Only
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Superior University
Allergic Contact Dermatitis, Osteoarthritis, Hip
Rate of Allergic Contact Dermatitis and Cosmetic Outcomes
The patients from the Department of Orthopaedics Center for Joint Replacement will be asked to participate in the study. These patients will be randomized to one of three wound closure products, Sylke adhesive dressing, Exofin…
- Conditions
- Allergic Contact Dermatitis, Osteoarthritis, Hip, Osteoarthritis, Knee
- Trial name
- NCT06957444
- Testing
- Sylke Adhesive Dressing, Exofin Skin Glue, Suture Strip Plus
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- West Virginia University
Tibial Fractures
New Bone Fixation Plate for the Repair of Tibial Avulsion Fracture of Posterior Cruciate Ligament of the Knee
To construct a self-designed plate fixation device for posterior cruciate ligament reconstruction, aim to verify its advantages on anatomical knee stability, so as to achieve fracture healing and keep tension after posterior…
- Trial name
- NCT03059368
- Testing
- new bone fixation plate with screw
- Volunteers
- 20 people
- Sponsor
- Cangzhou Central Hospital
ACL Tear
CT Evaluation of ACL Anatomical Reconstruction
Our research is to evaluate the position and length of femoral tunnel, and to examine whether knee stability and clinical functional outcomes are better while using two-portal or three-portal technique .
- Trial name
- NCT06575543
- Testing
- CT
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Assiut University
Ligament; Laxity, Recurrent Patellar Dislocation
Clinical Significance and Coexistence of Polymorphisms of Individual Collagen-coding Genes
The purpose of this study is to assess correlation between recurrent patella dislocation and genetic polymorphism rs1800012 of the COL1A1 Gene and rs12722 of the COL5A1 Gene.
- Trial name
- NCT05763108
- Testing
- genetic test, Beighton joint laxity test
- Where
- 2 sites in Poland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Polish Mother Memorial Hospital Research Institute
ACL Injury
Multimodal Assessment of Knee Conditions in Rehabilitation
The purpose of this study is to assess ACL injury and other pathological knee conditions from the combination of signals that are known to provide information on the knee joint.
- Trial name
- NCT03608189
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- University of Oulu
Osteoarthritis, Knee
MR Imaging of Knee Osteoarthritis and Acute Knee Injuries
The purpose of this study is to use better magnetic resonance imaging (MRI) techniques to examine the knee and the bony and soft tissue changes so as to better predict the progression of osteoarthritis and acute knee injuries.
- Trial name
- NCT00504114
- Testing
- ACL Reconstruction Surgery, Cartilage Resurfacing Surgery, Total Knee Replacement
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Meniscus Tear, Tibial, Osteoarthritis, Knee
Arthroscopic Partial Meniscectomy Versus Exercise Therapy for Meniscal Injuries in Older Patients, a 5 Year Follow up.
Arthroscopic partial meniscectomie (APM) offers little short-term to medium-term benefit above sham surgery or non-surgical management for knee function in most patients with a symptomatic degenerative meniscus tear.
- Trial name
- NCT05068843
- Testing
- arthroscopic partial meniscectomy, Physical therapy
- Volunteers
- 321 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
ACL Injury, ALL
ACL Reconstruction With/Without ALL Reconstruction
This study will compare Anterior Cruciate Reconstruction with or without Anterolateral Ligament Reconstruction in patients with ACL injury.
- Trial name
- NCT05461625
- Testing
- ACL reconstruction, ALL anatomic, ALL tenodesis
- Where
- Poland
- Volunteers
- 762 people, healthy volunteers welcome
- Sponsor
- Centre of Postgraduate Medical Education
Cerebral Palsy, Muscular Dystrophy
Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders
Background: People with cerebral palsy, spina bifida, muscular dystrophy, or spinal cord injury often have muscle weakness and problems controlling how their legs move. This can affect how they walk.
- Conditions
- Cerebral Palsy, Muscular Dystrophy, Spina Bifida, Incomplete Spinal Cord Injury
- Trial name
- NCT05726591
- Testing
- EA-KAFO
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
OsteoArthritis Knee
A Comparison of 2-octyl Cyanoacrylate Skin Adhesive and Polyester Mesh for Wound Closure in Total Knee Arthroplasty, A Randomized Controlled Study
The goal of this randomized controlled study is to investigate the Efficacy of Using skin adhesive (Dermabond) and skin adhesive with polyester mesh (Dermabond Prineo )for Wound Closure in Total Knee Arthroplasty, The main…
- Trial name
- NCT06232018
- Testing
- Skin adhesive (Dermabond), skin adhesive + polyester mesh (Dermabond prineo)
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Pooriwat Lertsurawat
Orthopedic Disorders, Injury of Anterior Cruciate Ligament
Injection Pressure & Adductor Canal Block
This is a prospective, randomized, single-blinded human clinical trial that will examine how injection pressure influences the spread of a given volume of injectate in the adductor canal, during adductor canal nerve block.
- Trial name
- NCT02563990
- Testing
- High Pressure Injection, Low Pressure Injection
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Miami
Anterior Cruciate Ligament Injuries, Meniscus Lesion
The Effect Of Addıtıonal Surgery On Muscle Strength, Proprıoceptıon And Balance In Anterıor Crucıate Lıgament Surgery
Meniscal tears and RAMP lesions are frequently seen together with ACL injuries. The aim of this study was to evaluate the effects of meniscus repair and RAMP lesion repair ACL reconstruction surgery in terms of muscle strength…
- Trial name
- NCT06319040
- Testing
- Muscle strength measurement, Knee joint proprioception, Balance
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medipol University
Anterior Cruciate Ligament Injuries
The Effects of Knee Extension Constraint Rehabilitation After ACL Reconstruction
To develop new prevention programs for non-contact ACL injuries that do not require additional training time and assistance from a sports medicine professional personnel.
- Trial name
- NCT04464902
- Testing
- brace1, brace2, No Intervention
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Lower Limb Amputation Above Knee (Injury)
The CYBERnetic LowEr Imb coGnitive Ortho-prostheis Plus Plus, 2nd Clinical Study (CLs++)
The aim of the project is to evaluate the efficacy of the Cyberlegs X-leg in people with a unilateral transfemoral (above the knee joint) and transtibial (under the knee joint) amputation.
- Trial name
- NCT04129853
- Testing
- Cyberlegs Xleg
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
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