Clinical trials: Wound Infection
Surgical Site Infection, Post-Op Complication
Perioperative Immunonutrition in Patients Undergoing Gynecologic or General Elective Surgery (PURPOSE)
The objective of the implementation pilot is to assess the practicality of introducing a perioperative immunonutrition protocol into a hospital environment as well as a true measure of impact on the rate of surgical site…
- Trial name
- PURPOSE (NCT04057092)
- Testing
- Dietary Supplement INergy-FLD
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Adult Women Living With HIV/AIDS, Intimate Partner Violence
Clinic-Community Bridge to Improve Health Outcomes for Abused Women Living With HIV/AIDS
Women living with HIV/AIDS (WLWHA) in Baltimore experience disproportionately high rates of intimate partner violence (IPV), housing instability, and food insecurity, which adversely affect health outcomes.
- Trial name
- Bridges (NCT07553312)
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Sepsis, Trauma Injury
Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis
Adverse outcomes in surgical sepsis patients are secondary to dysregulated emergency myelopoiesis, and expansion of myeloid-derived suppressor cells.
- Trial name
- NCT05110937
- Testing
- Blood sampling
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Florida
Endotoxemia, Systemic Inflammatory Response
PK/PD of EA-230 During Endotoxemia
EA-230 is a newly developed synthetic compound with anti-inflammatory properties. Pre-clinical data indicate that EA-230 may be a valuable treatment for systemic inflammation resulting from a variety of causes such as surgery…
- Trial name
- NCT02629874
- Testing
- EA-230, Endotoxin
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Surgical Site Infection, Complication of Surgical Procedure
Topical Antibiotics in Surgical Site
Ankle fractures are one of the most common injuries in traumatology. It is the fourth most common fracture in general population after hip, wrist, and hand fractures.
- Trial name
- NCT05363462
- Testing
- Vancomycin 1000 MG
- Where
- Mexico
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Nuevo Leon
Healthy Participants, Intrusive Memories
Understanding Reactions to Emotional Material in the Media During COVID-19
This feasibility study aims to adapt a protocol usually run in the laboratory in the Psychology Department for healthy participants (including the trauma film paradigm (James et al., 2016) and a simple cognitive task…
- Trial name
- NCT04608097
- Testing
- Simple cognitive task intervention
- Where
- Sweden
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Spinal Stenosis Lumbar, Surgical Site Infection
Efficacy of ActiveMatrix on Spinal SSI Rate
This clinical trial seeks to provide high level of evidence on the efficacy of ActiveMatrix primarily on spinal surgical site infection rate.
- Conditions
- Spinal Stenosis Lumbar, Surgical Site Infection, Back Pain Lower Back Chronic
- Trial name
- NCT05297513
- Testing
- ActiveMatrix
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
WOUNDS
Efficacy Study of Ultrasound-Assisted Debridement to Influence Wound Healing
The UltraHeal Study is a randomized controlled trial to compare healing response of low frequency contact ultrasonic-assisted debridement in addition to best practice wound care to best practice wound care alone in a Vascular…
- Trial name
- UltraHeal (NCT01973361)
- Testing
- Ultrasound debridement, Best practice wound care
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Anxiety, Pain
Text Message Study
The objectives of this double-blind, randomized, controlled study are to evaluate the efficacy of maintaining contact with low-back pain patients through text messaging and emailing, to decrease anxiety levels, pain, number of…
- Conditions
- Anxiety, Pain, Surgical Site Infection
- Trial name
- NCT01789697
- Testing
- cellular device/computers
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Duke University
Autism With High Cognitive Abilities, COVID-19 Pandemic
The Impact of Covid-19 Pandemic On The Children With Autism Spectrum Disorder
The Covid-19 outbreak has caused families and individuals to change their life routines and eating habits, and has affected their psychology, especially for children with autism, due to the change in their routines.
- Trial name
- NCT05197634
- Testing
- Not Applicable (observation)
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Silicosis, Tuberculosis
Silicosis and Silicotuberculosis Among Small Scale Gemstone Miners in Northern Tanzania
Artisanal, small-scale mining (ASM) is a large and essential component of the world's economy. Despite attendant risks, there is little research into risks to the health of artisanal miners.
- Conditions
- Silicosis, Tuberculosis, Silicosis; With Tuberculosis
- Trial name
- SilicoTB (NCT06403800)
- Testing
- No intervention
- Where
- Tanzania
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- National Heart and Lung Institute
Covid19, Post Traumatic Stress Disorder
Post-traumatic Stress, Signs of Depression and Burnout Syndrome Among Nursing Home Staff in Occitanie During the COVID-19 Pandemic
Nursing home staff face multiple stresses during the Covid-19 pandemic including personal risk of infection, risk of transmission of the virus to residents and relatives, and risk of witnessing end-of-life scenarios under…
- Conditions
- Covid19, Post Traumatic Stress Disorder, Anxiety, Depressive Disorder
- Trial name
- PSY-COEHPAD-OC (NCT04916275)
- Testing
- Cognitive tests
- Where
- 3 sites in France
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Cross Sectional Hospital Based Study
Risk Perception Associated With Covid-19 Among Anesthetists
Since the outbreak of the COVID-19 pandemic, the anesthesiologists are involved in the riskiest interventions e.g. airway management, endotracheal intubation, and resuscitation.
- Trial name
- NCT04861272
- Testing
- Survey
- Where
- Saudi Arabia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- King Saud University
Sepsis, Acute Lung Injury(ALI)
Recovery of Physical Function After Critical Illness In Older Adults
The proposed study is a prospective, observational study assessing the recovery of muscle and physical function in patients surviving critical illness (n =150) at hospital discharge (baseline) and repeated serially.
- Trial name
- RETURN (NCT07225257)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
HIV Infections, Substance Use
Women Focused Encounters for Resilience Independence Strength and Eudaimonia
The goal of this combination Type 1 hybrid and observational study is to evaluate the impact of a peer delivered intervention of acceptance and commitment therapy (ACT) + exercise + social support to address the substance…
- Conditions
- HIV Infections, Substance Use, Trauma, Medication Adherence
- Trial name
- WE RISE (NCT06216600)
- Testing
- Acceptance and Commitment Therapy (ACT), Body weight circuit training, Empathetic social support
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
SARS-CoV Infection, Covid19
KIDney Injury in Times of COVID-19 (KIDCOV)
There is an unmet need to evaluate the impact of sub-clinical/mild COVID19 disease in the outpatient setting on prevalent and incident renal injury, as this data is currently unavailable.
- Conditions
- SARS-CoV Infection, Covid19, Corona Virus Infection, Acute Kidney Injury
- Trial name
- KIDCOV (NCT04705766)
- Testing
- Urine Collection
- Where
- 3 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sepsis, Acute Kidney Injury Due to Sepsis
Renin Angiotensin Aldosterone System In Septic Kids
Prospective observational cohort study; pediatric sepsis vs. healthy pediatric subjects and pediatric sepsis with acute kidney injury (AKI) vs without AKI.
- Conditions
- Sepsis, Acute Kidney Injury Due to Sepsis, Acute Kidney Injury (Nontraumatic)
- Trial name
- RISK (NCT06295393)
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Surgical Site Infection, Surgical Wound Infection
Floraseal Versus Iodine Impregnated Adhesive Drapes
Infection after total joint arthroplasty can have devastating consequences. Adhesive drapes have been traditionally used at our institution to help reduce the risk of wound contamination and infection by superficial skin flora.
- Trial name
- NCT03466489
- Testing
- Floraseal
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Cutaneous Leishmaniases
Effectiveness, Safety and Feasibility of HECT-CL, in Quetta, Pakistan
This research studies the effect thermotherapy as treatment of Old World CL which is not invasive, non-toxic, and the short treatment. While the current standard treatment comprise daily painful injections with antimonials,
- Trial name
- HECT-CL (NCT03208543)
- Testing
- HECT-CL
- Where
- Pakistan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Medecins Sans Frontieres, Netherlands
Surgical Site Infections, Stress Hyperglycemia
Perioperative Glucose Monitoring and Treatment to Reduce Risk of Surgical Site Infections and Complications
This study is to determine if glucose monitoring and treatment in surgical procedures over 2 hours help to decrease the surgical site infection risk and reduce postoperative complications.
- Trial name
- POGM (NCT06765655)
- Testing
- Insulin Lispro Injection, glucose testing
- Where
- United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- St. Peter's Hospital, Albany, NY