Clinical trials: Wound Healing, open to volunteers
Pulp Necrosis
Lesion Sterilization and Tissue Repair Antibiotic Paste Versus Zinc Oxide and Eugenol Pulpectomy for Treatment of Primary Molars With Pulp Necrosis
The goal of this clinical trial is to compare the efficacy of lesion sterilization and tissue repair (LSTR) antibiotic paste versus zinc oxide eugenol (ZOE) pulpectomy for the treatment of primary molars with pulp necrosis in…
- Trial name
- LSTR (NCT07475364)
- Testing
- Group A - LSTR Therapy (CTZ Paste), Group B - ZOE Pulpectomy
- Volunteers
- 180 people
- Sponsor
- University of Faisalabad
Ventral Hernia, Postoperative Pain
Comparison of Two Plane Blocks Used in Open Ventral Hernia Repair Operations
The aim of this study is to compare the postoperative analgesic efficacy of bilateral erector spinae plane block and bilateral external oblique-intercostal plane block in patients undergoing open ventral hernia repair.
- Conditions
- Ventral Hernia, Postoperative Pain, Postoperative Nausea, Postoperative Vomiting
- Trial name
- NCT07163026
- Testing
- Erector Spine Plane Block, External Oblique - Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Cleft Palate
Nebulized Bupivacaine Analgesia for Cleft Palate Repair
In this study we introduce a potent local anesthetic; bupivacaine 0.5% in 0.5 mg/kg dose by nebulization as a preemptive analgesia to compare efficacy and safety in children with cleft palate repair.
- Trial name
- NCT04928352
- Testing
- Bupivacaine Hydrochloride, 0.9% saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Loxoprofen Sodium Patch, Local Incision
The Efficacy and Safety of Loxoprofen Sodium Patch in Relieving Postoperative Pain After Laparoscopic Surgery
Studies have shown that up to 80% of patients experience postoperative pain following laparoscopic surgery due to inflammation caused by surgical incisions and surrounding tissues, necessitating pharmacological relief.
- Conditions
- Loxoprofen Sodium Patch, Local Incision, Laparoscopic Cholecystectomy, Appendectomy, Laparoscopic
- Trial name
- NCT07591207
- Testing
- Loxoprofen Sodium Patch on the contralateral side, Loxoprofen Sodium Patch on the incision site
- Where
- 2 sites in China
- Volunteers
- 134 people
- Sponsor
- Beijing Tiantan Hospital
Diabetes Mellitus
Effect of Insulin Therapy by Ultrasonography in Wound Healing of Chronic Diabetic Patients
The main aim of the study is to determine the effect of transdermal application of insulin therapy by phonophoresis in wound healing in diabetic patients the main question of the study: is insulin phonophoresis is effective in…
- Trial name
- NCT06708975
- Testing
- Insulin therapy phonophoresis, Hyperpolarized light therapy and Standard wound cleaning and dressing.
- Volunteers
- 40 people
- Sponsor
- MTI University
Rotator Cuff Tear
Superior Capsular Reconstruction vs. Partial Repair for Massive Rotator Cuff Tears
Little evidence exists to guide treatment in patients with massive irreparable rotator cuff tears (MRCTS). Arthroscopic partial rotator cuff repair (PRCR) has the longest record of use.
- Trial name
- SCR (NCT03617562)
- Testing
- Superior Capsular Reconstruction, Partial Repair
- Where
- 2 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Sunnybrook Health Sciences Centre
Rotator Cuff Injuries
Effectiveness of Telerehabilitation as an Alternative to Outpatient Physiotherapy in the 1 Month After Arthroscopic Rotator Cuff Repair Surgery
The present study aims to verify whether telerehabilitation as an alternative to in-person treatment (both conducted by a physiotherapist) can be a valid option in terms of pain, recovery of the rom, shoulder functionality…
- Trial name
- NCT06744218
- Testing
- Standard Treatment, Experimental Treatment
- Where
- 2 sites in Italy
- Volunteers
- 46 people
- Sponsor
- Istituto Ortopedico Rizzoli
Wound Healing Complication, Oral Surgery
Comparison of Three Types of Sutures in Oral Surgery. Study of Bacterial Colonization, Tissue Reaction and Clinical Characteristics: Randomized Clinical Study
Considering the wide variety of surgical sutures currently marketed in the field of Dentistry, it was decided to conduct a study comparing the microbial adhesion and antibacterial activity of three different types of sutures used…
- Conditions
- Wound Healing Complication, Oral Surgery, Third Molar Extraction, Oral Infection
- Trial name
- NCT06864559
- Testing
- To Compare 3 different suture materials used in oral surgery
- Volunteers
- 24 people
- Sponsor
- Universidad de Granada
Cleft Lip Palate
Safety and Efficacy of Bone Bioengineering Kit With Stem Cells for Alveolar Cleft Repair
The objective of this study is to compare the safety and efficacy of a bone tissue engineering kit - composed of 10⁶ autologous mesenchymal stem cells derived from deciduous dental pulp combined with Bio-Oss® Collagen - with…
- Trial name
- NCT07305623
- Testing
- Bioengineering kit composed of stem cells from deciduous teeth and biomaterial., iliac crest bone graft surgery
- Where
- 2 sites in Brazil
- Volunteers
- 205 people
- Sponsor
- Instituto de Tecnologia do Paraná
Recurrent Endometrial Carcinoma, Unresectable Endometrial Carcinoma
Phase 1 Clinical Trial of Lenvatinib, Pembrolizumab and Hypofractionated Pelvic Radiation Therapy for pMMR Recurrent/Unresectable Endometrial Carcinoma
The purpose of this research study is to see if it is feasible to combine a fixed dose of pembrolizumab and a daily dose of oral lenvatinib, along with daily treatments of an abbreviated course of pelvic external beam radiation…
- Trial name
- NCT05603910
- Testing
- Lenvatinib, Pembrolizumab, Hypofractionated External Beam Radiation Therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Aaron Wolfson
Rectal Cancer
Short-course Radiation (SCRT) Followed by 6 Cycles of Cadonilimab Plus MFOLFOX6 As Neoadjuvant Therapy for Patients with Locally Advanced Rectal Cancer (LARC): a Multicenter, Two-arm Parallel, Open-label, Randomised Phase III Trial (NeoCaCRT-III)
The goal of this clinical trial is to learn if neoadjuvant short-course radiation (SCRT) followed by 6 cycles of cadonilimab plus mFOLFOX6 works to treat patients with locally advanced rectal cancer (LARC).
- Trial name
- NeoCaCRT-III (NCT06832917)
- Testing
- AK104 plus, Chemo only
- Volunteers
- 238 people
- Sponsor
- Wan He
Li-Fraumeni Syndrome
Willingness to Participate in a Trial Comparing Standard Genetic Counseling Versus Personalized Genetic Counseling
This study evaluates patients willingness to participate in a trial comparing standard genetic counseling versus personalized genetic counseling.
- Trial name
- NCT05126810
- Testing
- Questionnaire Administration
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- M.D. Anderson Cancer Center
Hand Injuries
Effect of Instrument Assisted Soft Tissue Mobilization on Hand Post Surgical Scars in Primary Flexor Tendons Repair in Zone v
this study will be conducted to investigate the effect of instrument assisted soft tissue mobilization on hand post surgical scars in primary flexor tendons repair in zone v
- Trial name
- IASTM (NCT07009197)
- Testing
- Instrument Assisted Soft Tissue Mobilization, traditional therapy
- Volunteers
- 42 people
- Sponsor
- Cairo University
Lynch Syndrome, Periodontal Disease
Periodontal Disease in Patients With Lynch Syndrome
The field of human microbiome research has undergone a revolution in its approach toward understanding how microorganisms influence the physiology of their host 1.
- Trial name
- SMILy_25 (NCT07600710)
- Testing
- periodontal charting for the diagnosis of periodontitis
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Rotundo Roberto
Corneal Ulcer
Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells
The proposed Conventional Cohort Expansion Study involves the use of Mesenchymal Stromal Cells (MSCs) are derived from the bone marrow.
- Trial name
- NCT05705024
- Testing
- Mesenchymal Stromal Cells, Control Solution
- Where
- 4 sites in United States
- Volunteers
- 38 people
- Sponsor
- University of Illinois Chicago
Trauma, Psychological, Traumatic Stress Disorder
Group Cognitive Processing Therapy for Women Survivors of Gender-Based Violence: Feasibility Study
Introduction: Post-traumatic stress disorder (PTSD) is a global health challenge requiring effective, evidence-based interventions, such as Cognitive Processing Therapy (CPT).
- Trial name
- HEALING-TRAUMA (NCT07897903)
- Testing
- Group CPT + TAU (Experimental)
- Volunteers
- 10 people
- Sponsor
- Universidad Complutense de Madrid
Wound Heal
Efficacy of SynEx Wound Rinse in Civilian Surrogates of Combat Injury Wounds
The purpose of this interventional study is to compare SynEx Wound Cleanser with the current routine care (Saline) in traumatic wounds.
- Trial name
- NCT05743283
- Testing
- SynEx Wound Cleanser, Saline
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Synedgen, Inc.
Neoplasms, Endometrial
A Study to Evaluate the Safety of Dostarlimab in Adult Participants in India With Recurrent or Advanced Endometrial Cancer (EC)
The goal of this study is to evaluate the safety profile of dostarlimab in Indian adults with recurrent or advanced endometrial cancer.
- Trial name
- NCT06897527
- Testing
- Dostarlimab
- Volunteers
- 100 people
- Sponsor
- GlaxoSmithKline
İnguinal Hernia, Post Operative Pain
Comparison of QLB and TFP Block for Postoperative Analgesia in Laparoscopic Inguinal Hernia
This randomized controlled trial aims to compare the effects of ultrasound-guided lateral Quadratus Lumborum Block (QLB) and Transversalis Fascia Plane (TFP) block on postoperative analgesia in patients undergoing laparoscopic…
- Trial name
- NCT07604259
- Testing
- Lateral Quadratus Lumborum Block, Transversalis Fascia Plane Block, Port Site Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University
Rotator Cuff Related Shoulder Pain, Shoulder Pain
Contextually Enhanced Exercise Programs for Rotator Cuff-Related Shoulder Pain
The goal of this clinical trial is to learn whether adding personalized contextual factors to an exercise program can improve pain and function in people with rotator cuff-related shoulder pain.
- Conditions
- Rotator Cuff Related Shoulder Pain, Shoulder Pain, Rotator Cuff Injuries
- Trial name
- CONTEXT-RCRSP (NCT07428070)
- Testing
- Contextually Fixed Exercise Program, Contextually Enriched Personalized Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Istanbul Nisantasi University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.