Clinical trials: Wound Heal
Cicatrix, Wound-healing
Investigation of the Efficacy of Zesteem in Accelerating Early Wound Healing
The purpose of this study is to investigate early wound healing of one application of four different doses of intradermal Zesteem (17β-Estradiol) in male subjects and female subjects two years post-menopausal.
- Trial name
- NCT00984386
- Testing
- Zesteem
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Renovo
Cicatrix, Wound Healing
Safety and Efficacy Study of Avotermin (Juvista) in Female Subjects
To assess safety and toleration, systemic exposure and anti-scarring potential of intradermal avotermin (Juvista) in young females.
- Trial name
- NCT00984581
- Testing
- Avotermin
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Renovo
Rotator Cuff Tear, Fatty Atrophy
Efficacy of an Amniotic Fluid Derived Allograft, (FlōGraft®) in Rotator Cuff Repairs: A Prospective Study
Rotator Cuff (RC) repair will be augmented with the injection of a human amniotic fluid derived allograft at the repair interface junction.
- Trial name
- NCT03379324
- Testing
- Superiority of augmented repairs, Fat degeneration of supraspinatus muscle
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Applied Biologics, LLC
Surgical Incisions
Prineo (Dermabond Protape) Versus Sutures for Full-thickness Surgical Incisions
This is a prospective, controlled, randomized, multi-center clinical study of up to 80 subjects with full thickness surgical incisions.
- Trial name
- NCT00557947
- Testing
- Suture, Dermabond Protape (Prineo)
- Where
- 5 sites in Belgium, Germany and 2 more
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ethicon, Inc.
Wounds, Wound Heal
G-Wound (VZ for Wound Treatment)
This is a prospective, randomized, open-label, controlled, exploratory trial that aims to investigate the local skin tolerability of topically administered VZ and to evaluate efficacy and safety parameters associated with…
- Trial name
- NCT04417647
- Testing
- VZ powder (purified clinoptilolite), Standard of care (SoC)
- Where
- Austria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Glock Health, Science and Research GmbH
Healthy
Clinical Evaluation of the Photoallergy Potential of Xenaderm Ointment
The product is being tested to see if exposure to light causes photoallergic reactions on the skin.
- Trial name
- NCT00645164
- Testing
- Ointment Vehicle, Xenaderm
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Healthpoint
Scar, Incision
A Safety and Efficacy Study to Evaluate AIV001 in Wound Healing Following Surgical Incision
To evaluate the safety, efficacy and pharmacokinetic profile of ascending concentrations of the study medication compared with vehicle in subjects with incisional wounds
- Conditions
- Scar, Incision, Abdominal, Wound (Morphologic Abnormality)
- Trial name
- NCT03639883
- Testing
- AIV001
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- AiViva BioPharma, Inc.
Chronic Wounds
Stromal Vascular Fraction From Lipoaspirate to Treatment of Chronic Non-healing Wound
This is a Phase I, open-label, single arm study to demonstrate the safety of Antria Cell Preparation Process during fat grafting augmented with autologous adipose derived stromal vascular fraction to demonstrate the safety and…
- Trial name
- NCT03882983
- Testing
- Antria Cell Preparation Process
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Antria
Healthy
Clinical Evaluation of the Phototoxic Potential of Xenaderm Ointment
The product is being tested to see if exposure to light causes toxic reactions on the skin.
- Trial name
- NCT00644917
- Testing
- Xenaderm
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Healthpoint
Cartilage Injury, Cartilage Damage
ProChondrix® CR Articular Cartilage Restoration Evaluation (PACE) Registry
The primary objective of this registry is to obtain long-term outcomes on ProChondrix CR in cartilage repair procedures of the knee, ankle, foot and hip.
- Trial name
- NCT04301258
- Testing
- Articular cartilage repair
- Where
- 5 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- AlloSource
Wound Heal, Wound Infection
Effectiveness and Tolerability of Fitostimoline Plus Cream and Gauze vs Connettivina Bio Plus Cream and Gauze
This study aims to compare the efficacy and clinical tolerability of two medical devices in gauze and cream containing the aqueous extract of triticum vulgare and polyhexanide in comparison with two medical devices containing…
- Conditions
- Wound Heal, Wound Infection, Wounds and Injuries
- Trial name
- FP (NCT04596124)
- Testing
- fitostimoline plus
- Where
- Italy
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Farmaceutici Damor Spa
Wound Healing
Patch Test of Benzalkonium Chloride Disinfectant Spray
The aim of the study is to evaluate the irritation potential of benzalkonium chloride disinfectant spray when placed in contact with normal human skin.
- Trial name
- NCT01762982
- Testing
- 0.13% Benzalkonium Chloride, SLS Solution, Normal Saline Water
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cicatrix, Wound Healing
Safety Study of Repeated, Escalating Doses of Intradermal Avotermin (Juvista)
The purpose of this study is to determine the safety and local toleration and histological effects of various dose levels of avotermin (Juvista) injected intradermally in healthy male volunteers.
- Trial name
- NCT00978302
- Testing
- Avotermin
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Renovo
Non-healing Wounds
Effect of Natrox Oxygen Wound Therapy on Non-healing Wounds and Implication of Remote Monitoring and Telehealth for Management in the Home.
Single center pilot study examining the effect of Natrox topical oxygen therapy on chronic wounds along with the introduction of remote monitoring and telehealth for home care management.
- Trial name
- NCT04746573
- Testing
- Natrox Topical Oxygen Therapy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Inotec AMD Limited
Wound
Assessment of Wound Healing, Cooling Efficacy and Local Tolerability of a Wound Care Hydrogel
Test the wound healing properties of the product as well as the cooling effect and tolerability of a wound care gel.
- Trial name
- NCT06309446
- Testing
- Zoralan Wound
- Where
- Germany
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oystershell NV
Healthy
Assessment of the Wound Healing Efficacy and Tolerance of a Medical Device on Wounds in Healthy Subjects.
The tested medical device is indicated for the treatment of wounds and small skin injuries. The intention of this study is to evaluate the tolerance and efficacy of the test product by measuring the recovery of the skin barrier…
- Trial name
- NCT04687839
- Testing
- Induction of suction blister, Transepidermal water loss (TEWL), Macrophotography
- Where
- Germany
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Cicatrix, Wound Healing
Investigation Into the Scar Reduction Potential of Prevascar (Interleukin-10)
The purpose of this study was to investigate the scar-reducing properties of eight doses of intradermal Prevascar (IL-10).
- Trial name
- NCT00984646
- Testing
- Prevascar
- Where
- United Kingdom
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Renovo
Chronic Diabetic Foot Ulcers
Nu-3 Topical Gel for Treatment of Diabetic Foot Ulcer
A PHASE 2a, MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED DOSE ESCALATING STUDY TO EVALUATE THE SAFETY AND TOLERABILITY OF TOPICALLY APPLIED BISPHOSPHOCIN NU-3 GEL TO CLINICALLY NONINFECTED CHRONIC DIABETIC FOOT…
- Trial name
- NCT05276401
- Testing
- 5% Bisphosphocin Topical Gel, 10% Bisphosphocin Topical Gel
- Where
- 5 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Lakewood-Amedex Inc
Skin Barrier Function, Wound Healing
Clinical Observational Study on Changes in Skin Physiological Parameters Following Ablative and Non-Ablative Fractional Laser Treatment at Different Doses
This clinical observational study investigates the dose-response relationship between laser energy intensity and skin damage/repair by applying different parameter sets of fractional ablative (CO2) and non-ablative (M22) lasers…
- Trial name
- NCT07561242
- Testing
- Ablative Fractional Carbon Dioxide Laser, Non-ablative Fractional Laser (1565 nm)
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Wound Healing
Efficacy of Topical TolaSure on Acute Induced Wounds in Healthy Participants
TolaSure is a topical gel for the promotion of accelerated wound healing. This phase II study will primarily assess the efficacy of TolaSure when applied to skin wounds created by punch biopsy in healthy participants.
- Trial name
- NCT04088357
- Testing
- TolaSure Topical Gel, Topical Vehicle Gel
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- BioMendics, LLC