Clinical trials: Women With PMS, open to volunteers
Premenstrual Dysphoric Disorder (PMDD)
Allopregnanolone and Dynamic GABA-A Receptor Plasticity in Selective Serotonin Reuptake Inhibitor Responsive Premenstrual Dysphoric Disorder
Premenstrual dysphoric disorder (PMDD) is a severe affective disorder impacting millions of women worldwide, thought to be due to altered sensitivity to hormone fluctuations across the menstrual cycle.
- Trial name
- BLOOM (NCT06704594)
- Testing
- sertraline 50 mg daily
- Where
- 2 sites in United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Premenstrual Syndrome
The Effects of Manual Lymphatic Drainage and Self-Manual Lymphatic Drainage
This randomized controlled study aims to compare the effects of manual lymphatic drainage (MLD), self-manual lymphatic drainage (self-MLD), and sham MLD on autonomic nervous system activity and premenstrual symptoms in women with…
- Trial name
- MLD-SMLD (NCT07814807)
- Testing
- Manual Lymphatic Drainage (MLD), Self-Manual Lymphatic Drainage (Self-MLD)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir Democracy University
PMS, PMDD
Microdosing LSD in Women With Premenstrual Disorders
The investigators aim to investigate the role of the serotonin 2A receptor in women with premenstrual disorders. This study uses a double-blind, randomized, controlled design with 3 arms: Intervention 1: 10 micg LSD for ~10 days…
- Trial name
- L4Her (NCT07189299)
- Testing
- LSD 10 μg every Day, LSD 10 μg every other day
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Friederike Holze
Menstrual Cycle, Menstrual Distress (Dysmenorrhea)
Menstrual Cycle Symptoms and Female Health
The complexity inherent to the hormonal fluctuations associated with the female menstrual cycle (MC) has contributed, from a methodological perspective in research, to the neglect of women's physiological characteristics and to…
- Conditions
- Menstrual Cycle, Menstrual Distress (Dysmenorrhea), Premenstrual Syndrome, Abnormal Uterine Bleeding (AUB)
- Trial name
- CICLOS (NCT07699224)
- Testing
- Prevalence
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Universidad Rey Juan Carlos
Sleep Disturbances, PMDD
Evaluating the Impact of Psychoeducation and Sleep-informed Workshop Targeting Sleep Concerns in Women and Individuals With Premenstrual Dysphoric Disorder
Premenstrual Dysphoric Disorder (PMDD) is a cyclical mood disorder characterized by emotional, cognitive, physical, and sleep-related symptoms that occur in the days leading up to menstruation and improve shortly after…
- Conditions
- Sleep Disturbances, PMDD, PMS
- Trial name
- PMDD (NCT07554950)
- Testing
- Psychoeducation and Sleep-Informed Workshop
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Premenstrual Syndrome, Premenstrual Dysphoric Disorder
CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life
This study evaluates the feasibility and efficacy of the Samphire Guided Care (SGC) program a 12-week structured digital health program combining clinician-led onboarding, at-home neuromodulation using the Lutea tDCS device…
- Conditions
- Premenstrual Syndrome, Premenstrual Dysphoric Disorder, Dysmenorrhea, Endometriosis
- Trial name
- CREST (NCT07679074)
- Testing
- Lutea Transcranial Direct Current Stimulation (tDCS) Device, Samphire Guided Care Program
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samphire Group, Inc.