Clinical trials: White Spot Lesion
White Spot Lesion
The Effect of ICON Treatment on WPL With Patients After Fixed Orthodontic Appliances
The aim of this study is to determine the effect of ICON on White spot lesions compared to CPP-ACPF plus.
- Trial name
- NCT03391180
- Testing
- ICON Remineralization, CPP-ACPF
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
White Spot Lesion of Tooth
Effect of Self Assembling Peptide on White Spot Lesion
During re-mineralization of white spot lesion, Will biomimetic self-assembling peptides improve the re-mineralizating effect of the post orthodontic white spot lesion compared to fluoride-based delivery systems?
- Trial name
- regeneration (NCT03930927)
- Testing
- Self Assembling peptide, remineralizing agent
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Raneen Ahmed
White Spot Lesion
Preventive Therapy of White Spot Lesions Using Different Remineralizing Agents in Children From 3 to 12 Years Old
Compare by clinical observation, photographs and fluorescence the efficacy of sodium fluoride, silanofluoride and thiefenfluoride in treating white spots.
- Trial name
- NCT04705428
- Testing
- FLUORINE VARNISH
- Where
- Spain
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Caries, Dental, Remineralization
Remineralizing Efficacy of Giomer Varnish vs. Fluoride Varnish in Management of White Spot Lesions in Adult Patients
To evaluate the remineralizing capability of biosmart S-PRG barrier coat varnish and its employment in clinical practice
- Conditions
- Caries, Dental, Remineralization, White Spot Lesion
- Trial name
- NCT05306691
- Testing
- Bio-smart Light Cured Protective Shield with bioactive S-PRG (Surface Pre- Reacted Glass ionomer) filler technology (PRG Barrier Coat) by (By SHOFU Inc., Japan).
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesion of Tooth, Long Term Adverse Effects
Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans
Orthodontic appliance causes increase in plaque accumulation, especially around brackets, wires and attachments. Advances in orthodontics in recent time have led to improved quality of appliance and treatment procedures…
- Conditions
- White Spot Lesion of Tooth, Long Term Adverse Effects, Caries, Dental, Orthodontic Appliance Complication
- Trial name
- NCT03004196
- Testing
- Probiotic Toothpaste, Dr. Reddy's Clohex, Control Group
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peoples University, Bhanpur, Bhopal
Child, Early Childhood Caries
Evaluation of Remineralizing Efficacy of Combination Varnishes on White Spot Lesions in ECC Children
The remineralizing efficacy of 3 fluoride varnishes were assessed in children with white spot lesion under 6 years of age ( children with early childhood caries)
- Trial name
- NCT03360266
- Testing
- Sodium Fluoride with CPP-ACP varnish, sodium fluoride with ACP varnish, 5% Sodium Fluoride Varnish
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Indira Gandhi Institute of Dental Science
White Spot Lesion of Tooth, Orthodontic Treatment
S-PRG Filler for Preventing White Spot Lesions During Orthodontic Treatment
White spot lesions are early areas of enamel demineralization that may develop during orthodontic treatment with fixed braces. This study aims to evaluate the effectiveness of S-PRG Barrier Coat in preventing white spot lesions…
- Conditions
- White Spot Lesion of Tooth, Orthodontic Treatment, Enamel Demineralization, Fluoride Varnishes
- Trial name
- SPRG-WSL (NCT07839780)
- Testing
- S-PRG Barrier Coat, S-PRG Barrier Coat + 5% Sodium Fluoride Varnish, 5% sodium fluoride varnish
- Where
- Malaysia
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Caries
Effect of CPP-ACP With/Without Fl on White Spot Lesion,Salivary pH and fl Release in High Caries Risk Patients
Effect of CPP-ACP pastes with/without Fluoride on White spot lesion progression, salivary pH and fluoride release in high caries risk Patients, over 3 month period using VistaCam, Digital pH meter and Selective ion electrode.
- Trial name
- NCT03656432
- Testing
- CPP-ACP paste
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesion of Tooth
Clinical Outcomes, Cost-Effectiveness and Patient Satisfaction of Two Resin Infiltration Systems for The Management of White Spot Lesions
The aim of this study is to clinically evaluate and compare the color matching of white spot lesions (WSLs) following treatment with two resin infiltration systems: ICON resin infiltration and I-Mate resin infiltration.
- Trial name
- NCT07799350
- Testing
- light cured low viscosity resin infiltration
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesion, Orthodontic Treatment
MI Varnish for the Prevention of White Spot Lesions
The current study aimed to determine if MI Varnish has an effect in preventing the formation of white spot lesions for patients undergoing orthodontic treatment.
- Trial name
- NCT03446690
- Testing
- MI Varnish, Control group
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
White Spot Lesions
Effect of BG Versus RI on the Depth of WSL
The aim of this in vitro study is to assess the mean lesion depth improvement and hardness of artificial white spot lesions by comparing the effects of bioactive glass toothpaste and resin infiltration (ICON).
- Trial name
- NCT07770724
- Testing
- Bioactive Glass (NovaMin), Resin Infiltration (ICON), Fluoride Toothpaste
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Riphah International University
White Spot Lesions
Preventive Potential of Fluoride Sealants in Adolescent Orthodontic Patients
The aim of this trial is to investigate the potential of using an adhesive bonding agent that also acts as a fluoride sealant when placing fixed orthodontic appliances in adolescent patients, as an alternative to regular bonding…
- Trial name
- NCT07691879
- Testing
- Use of a bonding agent to place the orthodontic appliance, Use of fluoride releasing bonding agent to place the orthodontic appliance
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sigmund Freud PrivatUniversitat
White Spot Lesion of Tooth
Effect of Low-viscosity Resin Infiltration on Color Change of Enamel White Spot Lesions
this study aimed to assess the effect of the application of the low-viscosity Icon resin infiltrate on the color change of the diagnosed white spot enamel lesions (WSLs) over 3-, 6-, and 12-m follow-up periods.
- Trial name
- NCT05757440
- Testing
- Icon resin application
- Where
- Egypt
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Remineralization
Clinical Efficacy of Different Remineralizing Agents in Treatment of White Spot Lesions
The aim of the present study is to evaluate the efficiency of Self-assembling Peptide P11-4, Tricalcium Phosphate Fluoride Varnish, 5% F- and 5% fluoride varnish in remineralization of WSLs in primary dentition among a group of…
- Trial name
- NCT05064137
- Testing
- Monomeric self - assembling peptide P11-4, Tricalcium phosphate fluoride varnish, 5% F-, fluoride varnish (5% sodium fluoride)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth, Moringa Oleifera
Remineralization Efficacy of Moringa Oleifera Varnish Vs MI Varnish in Initial Carious Lesions Over 6 Months Follow Up: a Randomized Controlled Clinical Trial
This randomized clinical trial aimed to test the remineralization effect of laboratory prepared Moringa Oleifera based varnish compared to MI varnish (CPP-ACP) on incipient carious lesions.
- Trial name
- NCT06905379
- Testing
- Moringa Oleifera, Varnish
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesion of Tooth
Efficacy of Different Agents in Treatment of Initial Caries on Smooth Surfaces in Permanent Teeth in Children
White spot lesions (WSL) are characterized by an apparently intact outer surface and a demineralized subsurface, and are considered the first clinical sign of dental caries.
- Trial name
- NCT05206539
- Testing
- Self-assembling peptide (P11-4), CPP-ACFP, Resin infiltration
- Where
- Bulgaria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
White Spot Lesions
Compare the Efficacy of the Remineralization Agents on the White Enamel Lesions
The purpose of this study is to determine whether Fluoride varnish + calcium (Clinpro White Varnish) and polipeptide solution (Curodont Repair) are effective in the treatment of remineralization therapy.
- Trial name
- NCT02341872
- Testing
- Clinpro White Varnish (fluoride + calcium varnish), Curodont Repair
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ege University
White Spot Lesions, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Assessing the Effects of Resin Infiltration and Resin Modified Glass Ionomer on the Color Changes of White Spot Lesions in a Clinical and Laboratory Setting
The goal of this clinical trial is to assess the efficacy of "Icon® resin infiltration" and "VanishTM XT varnish" in restoring the appearance of white spot lesions WSLs in healthy children affected with anterior white spot…
- Conditions
- White Spot Lesions, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth, Enamel Hypomineralization
- Trial name
- RI (NCT06696105)
- Testing
- Resin infiltration, Vanish XT varnish (resin modified glass ionomer restoration)
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Demineralization, Tooth, White Spot Lesion of Tooth
Preventive Effects of Silver Diamine Fluoride on Early Enamel Caries
Fixed orthodontic patients are at risk of developing dental caries. Topical application of fluoride varnish (FV) around the orthodontic brackets and using fluoridated mouth rinses have been suggested to prevent the formation of…
- Conditions
- Demineralization, Tooth, White Spot Lesion of Tooth, Fixed Appliances, Early Caries Lesions
- Trial name
- NCT06797882
- Testing
- Silver diamine fluoride- potassium iodide, Fluoride varnish, 0.9 % saline
- Where
- Malaysia
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
White Spot Lesion of Tooth
Effect of Diode Laser With Dye and Remineralizing Agent on Surface Area of White Spot Lesions by Using Digital Subtraction Radiograph Techniques.
The current study was conducted to compare effect of diode laser and perio green dye with reminerlizing agent on surface area white spot lesions by using digital subtraction radiographic techniques.
- Trial name
- NCT07818655
- Testing
- remin pro
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University