Clinical trials: Well-being
Schizophrenia
PREvent First Episode Relapse (PREFER)
Many patients who have recently received a diagnosis of schizophrenia (e.g., "first-episode schizophrenia") respond very well to their antipsychotic medication when they are acutely ill.
- Trial name
- NCT00220714
- Testing
- atypical antipsychotics:oral vs. long-acting route, Family Psychoeducation
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- State University of New York - Downstate Medical Center
Anger, Smoking Cessation
Computerized Anger-Reduction Treatment for Smoking Cessation
Problematic anger is a strong predictor of failed attempts at smoking cessation. The investigators proposed study seeks to evaluate whether a novel 8-session computerized anger-reduction treatment improves quit rates among…
- Trial name
- NCT02413814
- Testing
- Anger Reduction Treatment, Control Condition
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Florida State University
Sleep Apnea Syndromes
Efficiency of a Phone Coaching for Sleep Apnea Hypopnea Syndrome Patients
Background: Continuous Positive Airway Pressure (CPAP) remains the reference treatment for moderate to severe forms of the Sleep Apnea/Hypopnea Syndrome (SAHS).
- Trial name
- NCT02435355
- Testing
- telephone-based counselling
- Volunteers
- 379 people, healthy volunteers welcome
- Sponsor
- Sadir Association
Social Isolation, Aging
A Personalized Health Behavior System
The objectives of this study are to examine the usability and efficacy, for diverse older adults, of a new tablet-based dynamic system: the Fittle Senior System (FSS) that will provide: (1) personalized behavior-change programs…
- Conditions
- Social Isolation, Aging, Physical Activity
- Trial name
- FITTLESenior (NCT03538158)
- Testing
- Intervention Condition, Control Condition
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Infective Endocarditis, Bacterial Infections
Healthrelated Quality of Life and Experiences of a Heart Rehabilitation Programme After Care for Infective Endocarditis.
How does health develop after Infective endocarditis (IE)? Can the health of patients with IE be improved by participation in the physical exercise training within cardiac rehabilitation program? Participants will: Answer…
- Conditions
- Infective Endocarditis, Bacterial Infections, Cardiac Rehabilitation, Patient Participation
- Trial name
- NCT06704048
- Testing
- Cardiac rehabilitation
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Halland
COVID-19, Long Haul
Covid-19 Long Haul Preventative and Health Promotion Care Clinical Trial Acceleration Program.
Investigators are conducting a study on alternative treatments for patients who have received an current or previous positive COVID-19 diagnosis with mild-serve symptoms or undiagnosable condition after testing positive for…
- Trial name
- NCT06441955
- Testing
- Ritonavir-Boosted Nirmatrelvir (Paxlovid), Physiological Evaluation, Moderna COVID-19 Vaccine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Well- Konnect Healthcare Services and Research Firm
Health Adult Subjects
Dose-response Effects of Dietary Nitrate on Running Time-to-exhaustion and Neuromuscular Fatigue: a Randomized Crossover Exploratory Pilot Study
Background: Dietary nitrate is a natural compound found in vegetables such as beetroot and leafy greens. Previous research suggests that consuming nitrate before exercise may improve endurance and physical performance.
- Trial name
- Nitrate TTE (NCT07735455)
- Testing
- Dietary Nitrate
- Where
- Spain
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
Inflammation, Periodontal Disease
Advanced Oxidation Protein Product and Monocyte Chemoattractant Protein-1 in Periodontal Disease
This study investigates the levels of advanced oxidation protein product and monocyte chemoattractant protein-1 in gingival crevicular fluid in periodontal disease and health.
- Trial name
- NCT02848378
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Health Attitude, Knowledge, Attitudes, Practice
Development and Pilot Test of a Postnatal mHealth Intervention - Phase 2
The goal of the study is to assess the feasibility and acceptability of the optimized MeSSSSage intervention which was developed and revised based on the results of our initial pilot testing.
- Conditions
- Health Attitude, Knowledge, Attitudes, Practice, Post Partum Depression, Acceptability of Health Care
- Trial name
- MESSAGE (NCT04693585)
- Testing
- MESSSSAGE - live, MESSSSAGE - asynchronous
- Where
- India
- Volunteers
- 201 people
- Sponsor
- University of California, San Francisco
Metabolic Syndrome
Hydrogen-Rich Water and Metabolic Health in Adults: A 12-Week Randomized Trial
The HYDRO-RESPOND trial is a 12-week randomized controlled study investigating the effects of daily hydrogen-rich water (HRW) consumption on body composition and metabolic biomarkers in adults diagnosed with metabolic syndrome.
- Trial name
- HYDRO-RESPOND (NCT06968715)
- Testing
- Experimental 1: low-breath hydrogen, Experimental 2: high-breath hydrogen, Experimental 3: low-breath hydrogen
- Where
- Serbia
- Volunteers
- 40 people
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Health, Subjective
A Study to Evaluate the Pharmacokinetics and Safety of HIP1701 in Healthy Subjects
An open-label, randomized, single-dose crossover study to evaluate the pharmacokinetics and safety of HIP1701 in healthy subjects.
- Trial name
- NCT04087525
- Testing
- HIP1701, HGP1809
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Drug Use, Harmful Use
Preventing Drug Use in Low Income Clinic Populations
The proposed study will address the critical need to reduce illegal drug use, in particular drug use, and the occurrence of drug-related harm in low-income racially diverse patient populations at urban primary care safety-net…
- Trial name
- QUIT (NCT01942876)
- Testing
- Quit Using Drugs Intervention Trial, Health behavior maintenance
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Influenza
High-Dose Influenza Vaccine in Nursing Homes
The purpose of this study is to prospectively evaluate relative effectiveness of high dose influenza vaccine in preventing influenza mortality, hospitalization, and functional decline in a nursing home population in the U.S.…
- Trial name
- NCT01815268
- Testing
- HD Vaccine, SD Vaccine, Free Vaccine
- Where
- 3 sites in United States
- Volunteers
- 823 people, healthy volunteers welcome
- Sponsor
- Insight Therapeutics, LLC
Depression, Anxiety
Potency and Precision Investigation
The overarching goal of this study is to establish initial proof of mechanism for precision interventions in an adult population.
- Trial name
- PAPI (NCT06240091)
- Testing
- DISC-MA
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Woebot Health
Mental Health Issue, Family Relations
An Evaluation of a Family Counseling Intervention ("Tuko Pamoja") in Kenya
The purpose of this study is to evaluate a family counseling intervention, entitled "Tuko Pamoja" (Translation "We are Together" in Kiswahili).
- Conditions
- Mental Health Issue, Family Relations, Family Conflict, Child Mental Disorder
- Trial name
- C0058 (4C) (NCT06417918)
- Testing
- Tuko Pamoja, "We are Together" in Kiswahili
- Where
- Kenya
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Duke University
Neurology
Effectiveness of an Advanced Practice Nurse-Led Health Education Program (APN-HEALTH)
Advanced Practice Nursing (APN) has demonstrated a positive impact on improving health outcomes in various international clinical settings.
- Trial name
- APN-HEALTH (NCT07880613)
- Testing
- Individualized Health Education Program
- Volunteers
- 50 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Mindfulness, Emotional Well-being
MBSR in a Hispanic Immigrant Population in St. Louis
Hispanics are the largest ethnic group in the US as well as the fastest growing. Yet, despite being such a large population group, Hispanics are under-studied and under-represented in most studies of health, psychological…
- Trial name
- NCT03839589
- Testing
- Mindfulness Based Stress Reduction Adapated (MBSR-A)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Neonatal SEPSIS, Weight Gain
Effect of Early Feeding of Breast Milk
Breast milk is an extremely complex and highly variable biofliud that has evolved to nourish infants and protect them from disease whilst their own immune system matures.
- Conditions
- Neonatal SEPSIS, Weight Gain, Feeding Disorder Neonatal
- Trial name
- NCT03498989
- Testing
- preterm formula milk, exclusive breast milk
- Volunteers
- 100 people
- Sponsor
- Assiut University
Sleep Problems, Psychological
WhatsApp-based Psycho-socio-educational Intervention (WeLove) for Prevention of Psychological and Sleep Problems in Pregnant Women and Their Partners: A Three-arm Double-blinded Pilot Randomised Controlled Trial
Objectives: (1) evaluate the feasibility and acceptability of the WhatsApp-based psycho-socio-educational intervention (WeLove); (2) preliminarily examine the effects of the intervention on psychological symptoms (depression…
- Conditions
- Sleep Problems, Psychological, Well-Being, Psychological
- Trial name
- WhatsApp-based (NCT06768190)
- Testing
- WhatsApp as usual, WhatsApp-based psycho-socio-educational intervention (WeLove)
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Psychological Distress, Quality of Life
Prevention of Mental Health Problems Among Persons Without Personal Housing in the Context of the COVID-19 Epidemic
The Covid-19 pandemic is having a great impact on the long-term mental health and well-being. Reports on the levels of psychological distress are concerning.
- Conditions
- Psychological Distress, Quality of Life, Psychosocial Intervention
- Trial name
- RESPOND-FR (NCT05033210)
- Testing
- Psychological First Aid (PFA), Care as Usual (CAU), Doing What Matters in Times of Stress (DWM)
- Where
- 2 sites in France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases