Clinical trials: Weight Recurrence
Breast Cancer, Colorectal Cancer
Standard Therapy With or Without Dalteparin in Treating Patients With Advanced Breast, Lung, Colorectal, or Prostate Cancer
RATIONALE: Dalteparin may be effective in inhibiting the growth of blood vessels in tumors, decreasing the risk of metastatic cancer, preventing the formation of blood clots, and improving quality of life in treating patients…
- Conditions
- Breast Cancer, Colorectal Cancer, Lung Cancer, Prostate Cancer
- Trial name
- NCT00003674
- Testing
- dalteparin, standard therapy
- Where
- 20 sites in United States, Canada
- Volunteers
- 141 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Obesity, Morbid, Weight Regain After Bariatric Surgery
Weight Loss and Comorbidity Outcomes After Revisional Bariatric Surgery
Some people who have had weight-loss (bariatric) surgery do not lose enough weight, regain much of the weight they lost, see obesity-related diseases such as diabetes or high blood pressure return, or develop complications of the…
- Conditions
- Obesity, Morbid, Weight Regain After Bariatric Surgery, Insufficient Weight Loss After Bariatric Surgery, Complication of Bariatric Surgery
- Trial name
- NCT07880691
- Testing
- Revisional bariatric surgery
- Volunteers
- 96 people
- Sponsor
- Kasr El Aini Hospital
Deep Venous Thrombosis, Pulmonary Embolism
Comparison of Low and Intermediate Dose Low-molecular-weight Heparin to Prevent Recurrent Venous Thromboembolism in Pregnancy
This is a randomized-controlled open-label trial comparing two different doses of low-molecular-weight heparin (LMWH) in pregnant patients with a history of previous venous thromboembolism (VTE).
- Trial name
- Highlow (NCT01828697)
- Testing
- Low dose nadroparin, Intermediate dose nadroparin, Low dose enoxaparin
- Where
- 72 sites in United States, Belgium and 8 more
- Volunteers
- 1,110 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Anemia, Cancer Fatigue
Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia
This phase II trial studies the side effects of ex vivo-activated autologous lymph node lymphocytes infusion and to see how well they work in treating patients with chronic lymphocytic leukemia.
- Conditions
- Anemia, Cancer Fatigue, Chronic Lymphocytic Leukemia, Fever
- Trial name
- NCT02530515
- Testing
- Ex Vivo-activated Autologous Lymph Node Lymphocytes, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- M.D. Anderson Cancer Center
Anemia, Fatigue
Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia
This pilot clinical trial studies the side effects and best dose of metformin hydrochloride and ritonavir in treating patients with multiple myeloma or chronic lymphocytic leukemia that has returned after a period of improvement…
- Conditions
- Anemia, Fatigue, Fever, Lymphadenopathy
- Trial name
- NCT02948283
- Testing
- Laboratory Biomarker Analysis, Metformin Hydrochloride, Pharmacological Study
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- City of Hope Medical Center
Glioma Tumor Recurrence, Radiation Necrosis
Diffusion Tensor MRI to Distinguish Brain Tumor Recurrence From Radiation Necrosis
This study will examine the use of a variation of standard magnetic resonance imaging (MRI) called diffusion tensor MRI (DT-MRI) for distinguishing injured brain tissue due to radiation therapy (radiation necrosis) from the…
- Conditions
- Glioma Tumor Recurrence, Radiation Necrosis, Primary Brain Tumor
- Trial name
- NCT00285324
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Pancreatic Cancer, Cachexia
Study of Onivyde and 5-FU in Combination With Xilonix for Pancreatic Cancer With Cachexia
This study is being conducted to examine the safety of the investigational drug, Xilonix(™), in addition to standard doses of Onivyde® (nanoliposomal irinotecan) and 5- fluorouracil (5FU)/folinic acid (leucovorin) for pancreatic…
- Conditions
- Pancreatic Cancer, Cachexia, Weight Loss
- Trial name
- OnFX (NCT03207724)
- Testing
- Xilonix plus Onivyde and 5FU
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Andrew Hendifar, MD
Cervical Cancer, Endometrial Cancer
Value of Diffusion Weighted Magnetic Resonance Imaging in Detection of Recurrent Disease in Surgically Treated Cervical and Endometrial Cancer Patients
Endometrial and cervical cancers are one of the most common malignancies seen in females. Identification of recurrent disease in early phases of treatment carries a primary importance on the outcome of patients.
- Trial name
- NCT01710085
- Testing
- Diffusion weighted MRI (DW- MRI)- Philips Achieva 3.0T X, Netherlands, 2011
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Uludag University
Crohn's Disease
Comparison of Endoscopy and Diffusion-weighted Enterography-MRI for the Diagnosis of Crohn's Disease Recurrence Following Ileocolic Resection: a Pilot Study
Nearly three-quarters of patients with Crohn's disease have small bowel involvement and 80% of them will have complications that will require a surgical procedure, usually an ileocolonic resection with ileocolonic anastomosis.
- Trial name
- MRI-CROHN (NCT02867540)
- Testing
- MRI enterography
- Where
- France
- Volunteers
- 40 people
- Sponsor
- CHU de Reims
Cachexia, Squamous Cell Carcinoma
Testosterone for Treating Cachexia in Patients With Squamous Cell Carcinoma
RATIONALE: Testosterone may lessen weight loss and improve muscle size and strength in patients with cachexia caused by cancer. PURPOSE: This randomized phase I trial is studying whether testosterone administered during standard…
- Trial name
- NCT00878995
- Testing
- Testosterone Enanthate 100 MG/ML
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Venous Thromboembolism
Non Interventional Study of the Validation of the Ottawa Score in Cancer Patients With Venous Thromboembolism (VTE)
The purpose of this study is to validate the Ottawa score (risk of thromboembolic recurrences) in cancer patients with thromboembolic disease treated with tinzaparin (Innohep®)
- Trial name
- PREDICARE (NCT03099031)
- Testing
- Tinzaparin
- Where
- France
- Volunteers
- 420 people
- Sponsor
- LEO Pharma
Hereditary Clear Cell Renal Cell Carcinoma, Kidney Cancer
Sorafenib in Treating Patients With Locally Advanced or Metastatic Kidney Cancer
RATIONALE: Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Trial name
- NCT00727532
- Testing
- Sorafenib
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Northwestern University
Habitual Abortion
Low Molecular Weight Heparin and/or Aspirin in Prevention of Habitual Abortion
1 % of all pregnancies end in habitual/recurrent abortion. In about half of women with habitual abortions (HAB) hereditary or acquired (antiphospholipid antibodies) thrombophilia are observed.
- Trial name
- HABENOX (NCT00959621)
- Testing
- Aspirin, Klexane, Klexane and ASA
- Where
- Finland
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Atrial Fibrillation, Recurrence
Outcome of Overweight AF Patients Following Ablation With a Potential Weight Loss Medication ( GOAL-AF )
Atrial Fibrillation (AF) is the most common abnormal heart rhythm(arrhythmia) affecting about one in 40 people in England. Patients with AF often have symptoms ranging from palpitations and breathlessness, and a small number of…
- Conditions
- Atrial Fibrillation, Recurrence, Overweight and Obesity, Liraglutide
- Trial name
- GOAL-AF (NCT05221229)
- Testing
- Liraglutide plus upstream risk factors modification advice and consultation
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- University Hospital Birmingham
Thyroid Cancer, Relapse
Comparison DW-MRI vs FDG PET/CT in the Detection of Early Recurrence of Cervical Well-differentiated Thyroid Carcinoma
The purpose of the study is to evaluate the concordance between the 18F-PET/CT under thyrotropin stimulation and the diffusion-weighted Magnetic Resonance Imaging, in the detection of residual mass in 40 patients with partial…
- Trial name
- THYRIRMTEP (NCT02515084)
- Testing
- PET, MRI imaging
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Centre Henri Becquerel
Obesity, Inflammation
Inflammasome Activation and Cortisol Metabolism in Obese Women With Recurrent Miscarriage
The prevalence of obesity among women of reproductive age is increasing. Obesity represents a chronic low-grade inflammatory state and NLRP3 inflammasome plays a pivotal role in obesity-induced inflammation.
- Trial name
- NCT04275674
- Where
- Taiwan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Peritoneal Carcinomatosis, Peritoneal Metastases
Diagnostic Value of Diffusion-weighted Magnetic Resonance in High-risk Colorectal and Appendiceal Neoplasms
Diffusion-weighted magnetic resonance imaging (DWI/MRI) has been described in recent literature as a highly sensitive and specific modality for the detection of peritoneal metastases PM.
- Conditions
- Peritoneal Carcinomatosis, Peritoneal Metastases, Appendix Cancer, Appendix Neoplasm
- Trial name
- DWI-HighRisk (NCT05623787)
- Testing
- Whole-body diffusion-weighted magnetic resonance imaging
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Sterility
Low Molecular Weight Heparin to Improve Pregnancy Outcome in Patients With Recurrent Implantation Failure
The objective of this study is to determine the effect of Bemiparin, a low molecular weight heparin, on implantation rate in women with unexplained recurrent implantation failure undergoing IVF/ICSI treatment.
- Trial name
- BRIF (NCT02607319)
- Testing
- Bemiparin sodium
- Where
- Lebanon
- Volunteers
- 165 people
- Sponsor
- American University of Beirut Medical Center
Depression, Stage I Breast Cancer
Factors Affecting Weight Gain in Women Receiving Adjuvant Chemotherapy for Breast Cancer
RATIONALE: Chemotherapy may affect various factors that can lead to weight gain. PURPOSE: Clinical trial to evaluate factors that may affect weight gain in women receiving adjuvant chemotherapy for stage I, stage II, or stage…
- Conditions
- Depression, Stage I Breast Cancer, Stage IIIA Breast Cancer, Nutrition
- Trial name
- NCT00019643
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cachexia, Head and Neck Cancer
Low Antioxidant Diet in Controlling Cachexia in Patients With Oropharyngeal Cancer Receiving Chemotherapy and Radiation Therapy
RATIONALE: Eating a diet that is low in antioxidants may control cachexia in patients with oropharyngeal cancer. PURPOSE: This randomized phase I trial is studying the side effects of a low antioxidant diet in controlling…
- Conditions
- Cachexia, Head and Neck Cancer, Weight Changes
- Trial name
- NCT00486304
- Testing
- ADD
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center