Clinical trials: Weight Management
Obesity
Anti-psychotic Medication (New Use) Weight Loss Study
This is a pilot study to determine the safety and efficacy of an investigational product (IHBG-10) on weight change and changes in body composition in subjects who have just started taking (for less than three months) certain…
- Trial name
- NCT01272752
- Testing
- IHBG-10
- Where
- United States
- Sponsor
- Avera McKennan Hospital & University Health Center
Osteo Arthritis Knee and Hip
Predicting The Right Advice at The Right Time in Patients With Hip and Knee OsteoArthritis: the e-cOAch Cross-over.
This study aims to learn how symptoms and daily functioning change over time in people with hip or knee osteoarthritis (OA). The goal is to use this information to build computer models that can predict these changes.
- Trial name
- e-cOAch (NCT07423858)
- Testing
- Physical Activity program, Sleep program, Weight management program
- Where
- Netherlands
- Volunteers
- 600 people
- Sponsor
- UMC Utrecht
Preterm, Low Birthweight
Low-Cost and Reusable Thermal Jacket for Managing Preterm or Low Birth Weight Neonates.
Globally, over 15 million neonates are born preterm each year. They account for approximately 30% of global neonatal deaths and 19% of total neonatal deaths in Bangladesh.
- Conditions
- Preterm, Low Birthweight, Hypothermia Neonatal
- Trial name
- NCT06277843
- Testing
- Thermal Jacket
- Where
- Bangladesh
- Volunteers
- 10 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Obesity & Overweight
Effects of Exercise on Lipids and Endothelial Function in Youth
This study is for individuals who have a BMI that is at or above the 95th percentile and are participating in the Cincinnati Children's Hospital Healthworks! Structured weight loss program.
- Trial name
- NCT07409064
- Testing
- Exercise Program
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Overweight, Obesity
Pediatric Obesity Weight Evaluation Registry (POWER) Study
The main objective of this study is to establish a national pediatric obesity registry known as POWER (Pediatric Obesity Weight Evaluation Registry).
- Trial name
- POWER (NCT02121132)
- Where
- 38 sites in United States
- Volunteers
- 4,276 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Obesity
Individualized Lifestyle Intervention for Obesity Management Based on Obesity Phenotypes
The purpose of this protocol is to define an "individualized diet" approach based on obesity related phenotypes (pathophysiology obesity classification), which would increase weight loss, adherence, and weight loss maintenance.
- Trial name
- NCT04073394
- Testing
- Standard Lifestyle Intervention, Modified Lifestyle Intervention
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Overweight, Obesity
A Research Study Investigating NNC0247-0829 for Weight Management in People With Overweight or Obesity
This study looks at NNC0247-0829 (a potential new medicine) for weight management in people with overweight or obesity. The study looks at how NNC0247-0829 works in the body.
- Trial name
- NCT04010786
- Testing
- NNC0247-0829
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Novo Nordisk A/S
Metabolic Health, Weight Management
A Clinical Trial to Evaluate the Effects of A Supplement on Supporting Signs of Metabolic Health
This study evaluates the effects of the Love Wellness supplement Hello Burn Activate on supporting metabolic health in adult females.
- Conditions
- Metabolic Health, Weight Management, Body Confidence, Gut Health
- Trial name
- NCT07765394
- Testing
- Hello Burn Activate
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Love Wellness
Overweight, Obesity
A Research Study to Compare Two Different Forms of Once-weekly Semaglutide in Two Different Injection Pens
The study will look at how 2 different semaglutide versions reach and stay in the blood after injection. The study aims to show similar levels of semaglutide in the blood when using the different semaglutide versions.
- Trial name
- NCT04238962
- Testing
- Semaglutide (administered by DV3396 pen-injector), Semaglutide (administered by PDS290 pen-injector)
- Where
- Germany
- Volunteers
- 111 people
- Sponsor
- Novo Nordisk A/S
Obesity
Study of Five Different Methods Of Delivering A Lifestyle Modification Program for Weight Loss
The aim of the study was to compare 5 methods of delivering a weight loss lifestyle modification program to obese patients on a background of sibutramine.
- Trial name
- NCT00471172
- Testing
- Face-to-face counseling by a dietitian (months 1-3: weekly, months 4-6: every other week), Face-to-face counseling by a dietitian (monthly), Counseling by a dietitian via telephone (months 1-3: weekly, months 4-6: every other week)
- Where
- 12 sites in United States
- Volunteers
- 350 people
- Sponsor
- Pfizer
Weight Management, Obesity Prevention
Advancing Biopsychosocial Care Training Initiative
This project will compare two training approaches for US Preventive Services Task Force recommended obesity care in Federally Qualified Health Centers (FQHC) across four aims.
- Conditions
- Weight Management, Obesity Prevention, Obesity and Obesity-related Medical Conditions, Obesity and Overweight
- Trial name
- ABC Initiative (NCT07049861)
- Testing
- Comprehensive Multidisciplinary Obesity Care, Implementation as Usual Control
- Where
- United States
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity
Safety Study of the Inhibition of Agouti-related Protein (AgRP) for the Management of Obesity and Weight Loss
Multiple pathways including peripheral and central hormones and neurotransmitters are involved in the regulation of food intake and body weight. One of the most studied pathways involves the melanocortin receptor.
- Trial name
- NCT00779519
- Testing
- TTP435
- Where
- 12 sites in United States, Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- vTv Therapeutics
Obesity
Intensive Weight Loss Intervention Versus Bariatric Surgery for Adults With Severe and Complex Obesity: the LightBAR Randomised Trial
With this trial, the aim is to assess the benefits and harms of a non-surgical intensive weight loss intervention that includes total dietary replacements, behavioural support and weight-loss medication compared with bariatric…
- Trial name
- LightBAR (NCT06309238)
- Testing
- Intensive weight loss intervention, Bariatric surgery
- Where
- 14 sites in Denmark, United Kingdom
- Volunteers
- 500 people
- Sponsor
- Carsten Dirksen
Obesity Difficult Airway Airway Management
AI-Based Prediction of Difficult Airway in Bariatric Surgery
The aim of this prospective study is to evaluate the accuracy of artificial intelligence (AI) and machine learning algorithms in predicting difficult airways in patients undergoing bariatric surgery.
- Trial name
- AI-Airway (NCT07666074)
- Testing
- Preoperative Airway Assessment and Direct Laryngoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Child Obesity
Attrition in Pediatric Obesity Management
Our feasibility study will assess the feasibility and acceptability of Family Navigation (FN) to address attrition (dropout) in pediatric obesity management.
- Trial name
- NCT05403658
- Testing
- Family Navigation, Usual Care
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- University of Alberta
Body Weight
Health Effects of Substituting Sugary Beverages With Artificially-sweetened Beverages or Water
Sugar-sweetened beverages (SSBs) contribute an alarming ~7% of calories in the US diet among adults, making SSBs the single largest source of added sugar.
- Trial name
- SUB-POP (NCT04567108)
- Testing
- Maintain usual SSBs, Substitute to non-SSBs, Study app
- Where
- United States
- Volunteers
- 461 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Overweight, Metabolic Health
Study to Evaluate the Efficacy of an Avocado Dietary Supplement
This 16-week, randomized, triple-blinded, placebo-controlled study evaluates the effects of an avocado dietary supplement (Metavo) on healthy weight and blood glucose management in overweight adults.
- Conditions
- Overweight, Metabolic Health, Insulin Resistance
- Trial name
- METAVO-ONE (NCT07354308)
- Testing
- Metavo Supplement
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SP Nutraceuticals Inc.
Obesity
Awareness, Care & Treatment In Obesity Management
ACTION France is a cross-sectional, observational, descriptive, and exploratory survey-based study without collection of laboratory data. The study is not related to any specific treatment options or pharmaceutical product.
- Trial name
- ACTION-France (NCT05690789)
- Testing
- No treatment given
- Where
- France
- Volunteers
- 1,688 people
- Sponsor
- Novo Nordisk A/S
Endometrium Cancer, Physical Activity
Effect of Physical Activity Intervention on Overweight and Obese Patients With Endometrial Cancer
This study evaluated the clinical outcome of exercise management on patients with endometrial cancer treated with fertility preservation, including the effect of complete response rate, complete response time, recurrence rate…
- Conditions
- Endometrium Cancer, Physical Activity, Weight Management
- Trial name
- NCT06312917
- Testing
- Physical activity
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Peking University People's Hospital
Obesity
Tailored Worksite Weight Control Programs
Given the prevalence of overweight and obesity, worksite-based health promotion programs have been recommended due to their potential reach and social support impact.
- Trial name
- NCT01880060
- Testing
- INCENT weight loss program, Livin My Weigh
- Volunteers
- 1,790 people
- Sponsor
- Virginia Polytechnic Institute and State University