Clinical trials: Weight Management, open to volunteers
Obesity
Probiotic for Weight Management in Overweight and Obese Adults
To evaluate the impact of pasteurized Akkermansia muciniphila Akk11 capsules versus placebo on body composition (including body weight, BMI, body fat percentage, waist-to-hip ratio, wrist circumference, visceral fat area, and…
- Trial name
- NCT07507929
- Testing
- Probiotic
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Overweight and Obesity
Efficacy of mHealth Applications in Weight Management in a Population Affected by Overweight or Obesity
The purpose of this study is to determine the effectiveness of mobile health applications in improving health outcomes in patients with overweight and obesity.
- Trial name
- NCT05726942
- Testing
- Healthi
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Obesity, Malignant Neoplasm
A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant
This early phase I trial studies how well a behavioral weight loss intervention consisting of a smartphone application and coaching works for the promotion of weight loss in adolescents and young adults after a stem cell…
- Trial name
- NCT04453072
- Testing
- Interview, Media Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Obesity & Overweight
Xanthigen and Its Impact on Weight and Metabolic Health
Randomized, controlled, triple-blind clinical trial with three parallel arms based on the product consumed (low-dose experimental product, high-dose experimental product, and placebo product) and conducted at a single center to…
- Trial name
- XAN (NCT07519980)
- Testing
- Experimental group: Xanthigen®, Control product
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Menopause, Perimenopause
Multi-Acupoint Laser Therapy for Body Shape and Composition in Obese Menopausal Women
The purpose of this study is to integrate Traditional Chinese Medicine (TCM) theory and therapeutic methods with modern low-level laser stimulation on corresponding acupoints, applying this combined approach to the field of…
- Conditions
- Menopause, Perimenopause, Obesity, Overweight
- Trial name
- NCT07472881
- Testing
- Multi-acupoint low-level laser therapy, Diet and exercise guidance
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Healthy Participants
A Study to Investigate the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy Participants
The purpose of this study is to measure the pharmacokinetics (PK-how the body processes the study drug) of elecoglipron in healthy participants when taken by mouth as different formulations.
- Trial name
- NCT07723833
- Testing
- Elecoglipron Reference Formulation Dose A, Elecoglipron Test formulation 1 Dose A, Elecoglipron Reference Formulation Dose B
- Where
- 2 sites in United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Health Adult Subjects
Dihydroberberine Effects on Body Composition and Metabolic Health in Healthy Adults
The goal of this clinical trial is to evaluate whether dihydroberberine (DHB) supplementation can improve body composition, blood sugar control, energy levels, appetite, and mood in healthy adults with overweight or mild obesity.
- Trial name
- DHB (NCT07322679)
- Testing
- Dihydroberberine（DHB）
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nanjing Nutrabuilding Bio-tech Co., Ltd.
Pediatric Dental Anxiety, Dental Anxiety
Multisensory Approaches for Managing Pediatric Dental Anxiety
The purpose of this prospective, randomized, single-blind clinical study is to evaluate and compare the effectiveness of distraction using virtual reality (VR) glasses and deep-pressure stimulation using weighted blankets on…
- Trial name
- NCT07848542
- Testing
- Basic Behavior Guidance, Deep Pressure Stimulation, Virtual Reality Distraction
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Type 1 Diabetes, T1D
DASH-Obesity: Explainable AI for Family-Centric Personalized Weight Control in Adolescents and Young Adults With Obesity and Chronic Conditions
This prospective single-arm feasibility study evaluates the Adhera Caring Digital Program for Obesity (ACDP-O), a family-centered digital health intervention designed to support adolescents and young adults with…
- Conditions
- Type 1 Diabetes, T1D, Obesity & Overweight, Obesity Type 2 Diabetes Mellitus
- Trial name
- DASH-Obesity (NCT07638345)
- Testing
- Adhera Caring Digital Program-Obesity (ACDP-O)
- Where
- Spain
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Adhera Health, Inc.
Obesity, Overweight
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
This is randomized, double-blind, placebo-controlled study of the long-term efficacy, safety, and tolerability of multiple doses of aleniglipron in participants living with overweight or obesity and T2DM.
- Conditions
- Obesity, Overweight, Chronic Weight Management, Type2 Diabetes Mellitus
- Trial name
- NCT07654374
- Testing
- aleniglipron
- Where
- 74 sites in United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Patients Who Gain Weight or Stop Losing Weight After barıatrıc Surgery, Absence of Cognitive or Psychiatric Illness
THE EFFECT OF MOTİVATİONAL INTERVİEWİNG-BASED MİNDFULNESS INTERVENTION ON WEİGHT MANAGEMENT AFTER WEİGT LOSS,7SLİMMİNG SURGERY: A RANDOMİZED CONTROLLED TRIAL.
Obesity is one of the most critical health problems in developed and developing countries, recognized as a chronic disease that adversely affects both individual and societal health.
- Conditions
- Patients Who Gain Weight or Stop Losing Weight After barıatrıc Surgery, Absence of Cognitive or Psychiatric Illness, Not Having Previously Received Cognitive Awareness Training, Not Having Undergone Revision Surgery
- Trial name
- NCT07351214
- Testing
- A MİNDFULNESS İNİTİATİVE BASED ON MOTİVATİONAL İNTERVİEWİNG
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Duygu Ateş
Weight Management in Adult Patients With Obesity or Overweight
Phase I Study of XTL6001 Injection in Healthy and Obese Subjects
This is a multicenter, randomized, double-blind, placebo-controlled Phase I study to evaluate safety, PK and PD of single ascending dose (SAD) and multiple ascending dose (MAD) of XTL6001 injection in healthy and obese adult…
- Trial name
- NCT07205432
- Testing
- XTL6001
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shanghai Xitaili Biomedicine Technology co., Ltd.
Pregnancy, Postpartum
Usability Study of Gestational and Postpartum Weight Management Program
The principal aim of this study is to evaluate the usability of the Hope-D gestational and 6 months postpartum weight management program.
- Conditions
- Pregnancy, Postpartum, Obese Pregnant Women, Weight Management
- Trial name
- Hope-D_Use (NCT07272824)
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Gestational Weight Gain, Overweight and Obesity
Healthy Mom Zone Gestational Weight Gain Management Intervention 2.0
The goal of this clinical trial is to see if the enhanced HMZ 2.0 intervention with new control system/digital platform to regulate gestational weight gain (GWG) and impact maternal-infant outcomes while collecting implementation…
- Conditions
- Gestational Weight Gain, Overweight and Obesity, Pregnancy, Energy Balance
- Trial name
- HMZ Two (NCT05807594)
- Testing
- HMZ 2.0 Intervention, Attention Control Intervention
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Penn State University
Dyslipidemia, Insulin Resistance Syndrome
Prescription of Step Counts for Targeted Changes in Body Composition and Cardiometabolic Risk in Overweight/Obese Adults
The prevalence of overweight and obesity remains epidemic in the United States, with some of the highest rates seen in older adults.
- Conditions
- Dyslipidemia, Insulin Resistance Syndrome, Hypertension, Inflammation Chronic
- Trial name
- NCT07221279
- Testing
- Step counts for predictable changes in body weight/compositon and cardiometabolic risk
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kennesaw State University
Obesity, Overweight
HealthyTogether: RCT of a Dyadic Weight Management Intervention
Four in five Veterans have overweight or obesity. However, few eligible Veterans achieve meaningful weight loss in VA's national MOVE! Weight Management Program.
- Trial name
- NCT06619041
- Testing
- HealthyTogether
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Type 2 Diabetes Mellitus (T2DM), Food Effect
Food Effect, Efficacy and Safety of MKP10241 in Healthy and Obese Adult Participants, With and Without Diabetes
The goal of this intervention study is to evaluate the safety, tolerability and pharmacokinetics (PK) and pharmacodynamics (PD) of multiple doses of MKP10241 in obese participants with and without T2DM in 3 parts.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Food Effect, Safety and Tolerability, Obesity
- Trial name
- NCT07098663
- Testing
- MKP10241
- Where
- Australia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mankind Pharma Limited
Diabete Mellitus, Hypertension
Faisalabad Initiative of Research and Management of NCDs
The burden of noncommunicable diseases (NCDs) continues to rise globally, and they have become the leading cause of morbidity and mortality, accounting for over 70% of deaths worldwide¹.
- Conditions
- Diabete Mellitus, Hypertension, Hypercholerolemia, Obesity (Disorder)
- Trial name
- FIRM-NCD (NCT07676214)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Getz Pharma
Diabetes, Pre Diabetes
Jockey Club Precision Prevention Programme on Young Onset Diabetes
This is a community-based implementation program consisting of multiple components delivered by a multidisciplinary team to detect and prevent young onset diabetes with precision and value using biogenetic markers, digital tools…
- Conditions
- Diabetes, Pre Diabetes, Hypertension, Dyslipidemia
- Trial name
- NCT06693934
- Testing
- Risk assessment with biogenetic and clinical test to predict diabetes risk, Oral glucose tolerance test (OGTT) and cardiovascular-kidney-metabolic (CKM) risk factors, Medication
- Where
- Hong Kong
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Juliana CN Chan
Weight Management, Type 2 Diabetes
A Clinical Study to Evaluate the Effect of Different Dosing Conditions on the Pharmacokinetics of HRS9531 Tablets in Healthy Participants
The study is being conducted to evaluate the effects of different dosage regimen on the pharmacokinetics of HRS9531 tablets in healthy subjects.
- Trial name
- NCT06506175
- Testing
- HRS9531 tablets
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.