Clinical trials: Weight Control
Hypercholesterolemia, Overweight and Obesity
Metabolic Effect of an Innovative Chitosan Formulation
Chitosan is a natural polysaccharide of β-1,4-linked glucosamine residues deriving from chitin, a dietary fiber primarily obtained from fungal cell walls and the exoskeletons of various crustaceans (e.g.
- Trial name
- CHITOCHOL (NCT05188430)
- Testing
- Medical Device (Kaptufat®)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Sedentary Lifestyle, Obesity
Financial Incentives for Increasing Exercise
Participants will be employees of Genzyme who volunteer to participate in a study on motivating healthy behaviors, involving giving them goals for taking a certain number of steps per day, and increasing that number over time.
- Trial name
- NCT01043757
- Testing
- Financial incentives for increasing physical exercise
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Harvard University
Obesity, Overweight and Obesity
Investigation of the Effects of a Bifidobacterium Breve Strain on Fat Loss in Healthy Adults
Overweight has become a critical issue in North America and the market value of weight loss products is expected to rise as the population becomes more health-conscious and aware of the risks associated with excess body weight.
- Trial name
- NCT04677738
- Testing
- B. breve strain
- Where
- Canada
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Morinaga Milk Industry Co., LTD
Overweight and Obesity
EXerCise wEight Loss
The overall aim of this study is to investigate the effects of home-based resistance exercise programme on changes in body composition and strength during weight loss, in people living with obesity or overweight.
- Trial name
- EXCEL (NCT05702840)
- Testing
- Resistance exercise training + weight loss group, Weight loss only group (WL)
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Obesity and Overweight
BK329 and Body Fat Reduction
This clinical trial aims to determine whether BK329 reduces body fat in adults with overweight or obesity and to assess its safety.
- Trial name
- NCT06628791
- Testing
- BK329
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Overweight,Obesity
Dose-escalation and Food Effect Study of ZT006 in Healthy, Overweight and Obese Participants
ZT006 is an oral, long-acting glucagon-like peptide-1. This first-in-human study is designed to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of ZT006 in healthy, overweight and obese participants.
- Trial name
- NCT07307638
- Testing
- ZT006
- Where
- China
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Beijing QL Biopharmaceutical Co.,Ltd
Olive Oil Adverse Reaction, Nursing Caries
Effect of Enteral Olive Oil Supplement On Weight Gain and Development of Some Complications in Preterm
Objective: The objective of the present research is to compare the nutritional status, weight gain, length of hospital stay, and development of some complications in very low birth-weight (VLBW) infants who received and did not…
- Conditions
- Olive Oil Adverse Reaction, Nursing Caries, Enteral and Supplement Feeds Adverse Reaction, Preterm
- Trial name
- NCT05815849
- Testing
- Olive oil
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Obesity
Cerebral Blood Flow Changes in People With Obesity After Glucose Consumption
This study evaluates the hypothesis that a meal constituted of only glucose produces differences in the brain blood flow in people with obesity that are not observed in people without obesity.
- Trial name
- NCT02072694
- Testing
- 75 grams of glucose plus water solution, Pure water
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Eating Behavior, Metabolic Syndrome
Study of Eating Patterns With a Smartphone App and the Effects of Time Restricted Feeding in the Metabolic Syndrome
SwissChronoFood - Study of eating patterns with a smartphone app and the metabolic effects of time restricted feeding in metabolic syndrome The purpose of this study is to assess eating patterns among teenagers and adults with a…
- Conditions
- Eating Behavior, Metabolic Syndrome, Obesity, Dyslipidemias
- Trial name
- NCT03241121
- Testing
- Time restricted feeding, Regular dietary advices, Eating patterns
- Where
- 2 sites in Switzerland
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Preterm Birth, Feeding Behavior
Preterm Infant Oral Motor Intervention (PIOMI)
The purpose of this research; The aim of this study is to examine the effects of oral motor intervention (PIOMI) and combined kangaroo care applied to preterm babies on weight gain, oral feeding skills, transition to full oral…
- Trial name
- NCT06259604
- Testing
- PIOMI, PIOMI+kangaroo care
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Emotional Eating, Emotion Regulation
ACT-Based Group Therapy and Mobile Application Intervention for Emotional Eating
This study aims to evaluate the effects of an Acceptance and Commitment Therapy (ACT)-based group therapy program, combined with an ACT-based mobile app, on emotional eating, emotion regulation, and psychological flexibility in…
- Conditions
- Emotional Eating, Emotion Regulation, Overweight, Psychological Flexibility
- Trial name
- ACT-EE (NCT07559552)
- Testing
- ACT-Based Group Therapy, ACT-Based Mobile Application
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Obesity
Log2Lose: Incenting Weight Loss and Dietary Self-monitoring in Real-time to Improve Weight Management Among Adults With Obesity
This study involves an evaluation of whether providing small incentives weekly for dietary self-monitoring and/or weight loss improves short- and long-term weight loss. Participants can expect to be on study for 18 months.
- Trial name
- NCT04770909
- Testing
- Incentives for dietary self-monitoring and weight loss, Incentives for dietary self-monitoring, Incentives for weight loss
- Where
- 2 sites in United States
- Volunteers
- 706 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Obesity, Weight Change Trajectory
Evaluation of the Safety and Efficacy of Revita® DMR on Body Weight Maintenance in Subjects With Obesity Who Have Achieved at Least 15% Weight Loss on Tirzepatide
Fractyl is evaluating Revita Duodenal Mucosal Resurfacing (DMR) in the REMAIN-1 pivotal study, which is designed to include two cohorts - an open label cohort referred to as REVEAL-1, and a randomized cohort, which includes both…
- Conditions
- Obesity, Weight Change Trajectory, Weight Change, Body
- Trial name
- REMAIN-1 (NCT06484114)
- Testing
- Revita Duodenal Mucosal Resurfacing (DMR)
- Where
- 32 sites in United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Fractyl Health Inc.
Obesity, Fasting
The Effect of Intermittent Energy Restriction Using Meal Replacements in Overweight Chinese Subjects
Background and Aims: The "5:2 diet", a form of intermittent energy restriction, has been popularized in Europe and USA. The rationale behind this approach is that two days of dieting is potentially more achievable, yet long…
- Trial name
- NCT02606669
- Testing
- Meal Replacement
- Where
- Singapore
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Khoo Teck Puat Hospital
Overweight, Obesity
Efficacy of Olibra: A 12 Week Controlled Trial
Today's obesogenic environment, favors behavioral choices that lead to an excess of energy intake over expenditure, and consequently weight gain.
- Trial name
- NCT01416051
- Testing
- Olibra
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obese, Asthma
Aerosol Deposition in Asthmatic Obese Women Using Heliox
BACKGROUND: The aim of this study was to assess pulmonary deposition and distribution of radio-aerosol in obese and normal women, using 2-D planar scintigraphy.
- Trial name
- NCT02620956
- Testing
- nebulizing with heliox and oxygen
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jacqueline de Melo Barcelar
Malnutrition
Nutritional Intervention in a Cross-sector Model for the Rehabilitation of Geriatric Patients
Based on an established Follow-home-programme offered at discharge from hospital the aim of this study is to test a model of how nutritional intervention in elderly patients can be systematized and quality assured in the…
- Trial name
- NCT01776762
- Testing
- Individual nutritional therapy
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital at Herlev
Pregnant Women
Effectiveness of mHealth Education on Health Outcomes Among Pregnant Women
Gestational weight gain (GWG), weight gain of a mother during pregnancy, is an important determinant that influence the health outcomes of mothers and fetus.
- Trial name
- NCT05377151
- Testing
- Mobile application
- Where
- 3 sites in Malaysia
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Obesity
SMART: A Social and Mobile Weight Control Program for Young Adults
The Social/Mobile Approach to Reduce Weight (SMART) study is a 24-month randomized control trial designed to evaluate the hypothesis that weight status at 24 months will be significantly better for the SMART intervention…
- Trial name
- SMART (NCT01200459)
- Testing
- Social/mobile weight loss promotion intervention.
- Where
- United States
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Glucagon-like Peptide-1, Smoking Cessation
Smoking Cessation Facilitated by Glucagon-like Peptide-1 (GLP-1) Analogues
Cigarette smoking is the leading preventable cause of premature death worldwide. However smoking is a very difficult addiction to break whereby main reasons for not quitting or relapsing after cessation are the nicotine…
- Conditions
- Glucagon-like Peptide-1, Smoking Cessation, Weight Change, Body, Craving
- Trial name
- SKIP (NCT03204396)
- Testing
- Dulaglutide, 0.5 ml normal saline (0.9% sodium chloride [0.9% NaCl])
- Where
- Switzerland
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
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