Clinical trials: Weakness, Muscle
Stroke, Parkinson's Disease
Inpatient Physical Activity Function Through Enhanced Participation Levels in Animal-Assisted Therapy Programs
Thousands of canines are used for therapy in health care centers throughout the United States as part of a volunteer therapy team, yet little is known about the outcomes provided by these teams.
- Conditions
- Stroke, Parkinson's Disease, Muscle Weakness
- Trial name
- NCT02606006
- Testing
- Canine Animal-Assisted Therapy, Standard of Care Physical Therapy
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Frail Elderly Syndrome
Protocols and Guidelines for the Use of Digital Twins in Frail Older People
The Proto-Aging study aims to define experimental protocols and guidelines to enable the development of musculoskeletal models (digital twins) of elderly people, with the ultimate goal to comprehensively characterize frail elders…
- Trial name
- Proto-Aging (NCT05854316)
- Testing
- Comprehensive Biomechanical assessment
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Pelvic Floor Muscle Weakness, Postpartum
The Pelvic Floor Muscle Function in Chinese Primipara, a One-year Cohort Study
It is a prospective cohort study.The primiparas in six geographic regions of China are recruited to observe the natural recovery of pelvic floor muscle.
- Conditions
- Pelvic Floor Muscle Weakness, Postpartum, Primiparity
- Trial name
- NCT03506204
- Where
- China
- Volunteers
- 3,120 people
- Sponsor
- Peking Union Medical College Hospital
Muscular Atrophy, Muscle Weakness
Combined Effects of Nutritional and Exercise Countermeasures
The purpose of this study is to see if a combination of resistance exercises and amino acid capsules can reduce muscle loss and maintain muscle function during bedrest.
- Trial name
- NCT00447044
- Testing
- Resistance Exercise, diet orange soda, essential amino acids
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Severe Sepsis, Acute Respiratory Failure
Effect of Different Electric Muscle Stimulation in Patients With Severe Sepsis and Respiratory Failure
Rationale : Electric muscle stimulation reduced critical-illness related weakness in patients with severe sepsis and septic shock. But optimal protocol of the stimulation in unknown.
- Conditions
- Severe Sepsis, Acute Respiratory Failure, Muscle Hypotonia, Inflammation
- Trial name
- NCT01895647
- Testing
- EMS
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Mackay Memorial Hospital
Anterior Cruciate Ligament Injuries, Muscle Weakness
Changes in the Force-velocity Relationship of Knee Muscles After ACL Reconstruction
Anterior cruciate ligament (ACL) tear is a frequent and devastating injury in sport, especially in pivoting-contact disciplines.
- Trial name
- FoVeA (NCT05712109)
- Testing
- Follow-up after Anterior cruciate ligament reconstruction
- Where
- France
- Volunteers
- 103 people
- Sponsor
- University Hospital, Caen
Muscle Weakness
Mitigating Neural Hypoexcitability and Weakness During Disuse in Women
Clinical trial The goal of this clinical trial is to learn how muscle weakness and atrophy develop during short periods of arm immobilization and whether a type of exercise called cross-education can help reduce these effects in…
- Trial name
- MiND (NCT07166198)
- Testing
- Wrist immobilization, Resistance training, Resistance training rehabilitation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Muscle Weakness, Angiogenesis
Interactive Hand Exercise Game on Grip Strength and Vascular Maturation
Hemodialysis is currently the most commonly used renal replacement therapy. Compared with arteriovenous graft, central venous catheter, and autologous arteriovenous fistula, the possibility of postoperative re-dredging is low and…
- Trial name
- NCT05493046
- Testing
- Interactive Hand Exercise Game, Soft ball exercise ( routine care)
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University
Traumatic Brain Injury, Weakness, Muscle
Physical and Mental Practice for Bimanual Coordination Rehabilitation
Traumatic Brain Injury (TBI)patients often suffer from loss of muscle strength in the hand and foot, decrease in coordination and high muscle tone (spasticity).
- Conditions
- Traumatic Brain Injury, Weakness, Muscle, Coordination Impairment
- Trial name
- NCT03817086
- Testing
- Hand coordination and mental practice, Hand coordination and action observation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Kessler Foundation
Post Intensive Care Unit Syndrome, Critical Illness
Improving Recovery After Critical Illness
Rationale: Survival rates of patients with critical illness have increased due to improved facilities and treatment methods in the intensive care unit (ICU).
- Conditions
- Post Intensive Care Unit Syndrome, Critical Illness, Malnutrition, Muscle Weakness
- Trial name
- IMPROVE (NCT05182086)
- Testing
- Group physical therapy and dietary improvements
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Frisius Medisch Centrum
Amyotrophic Lateral Sclerosis & Other Neuromuscular Disorders
Using Gaze to Enable Head-neck Movements in Patients With Head Drop
The investigators will develop and evaluate controllers for a powered neck exoskeleton in patients with amyotrophic lateral sclerosis (ALS) to understand how to allow adequate personalization and function and achieves…
- Trial name
- NCT07836751
- Testing
- neck exoskeleton controller
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Utah
Patellofemoral Pain Syndrome
Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain
Background: Researchers are interested in how the muscles affect the movement of the knee cap. These muscles may be related to different kinds of knee pain that are not caused by an injury or a disease.
- Trial name
- NCT01862731
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Burns - Multiple, Critical Illness
Reduction of Muscle Catabolism Through Brain Activation in Burn Patients
Patients with extensive burn injuries frequently develop severe skeletal muscle wasting and weakness as part of critical illness-related myopathy and neuropathy.
- Conditions
- Burns - Multiple, Critical Illness, Muscle Weakness
- Trial name
- REMBRANT (NCT07435402)
- Testing
- Burn-Bundle Extended Rehabilitation Program, Isoflurane Inhalational Sedation, Functional Proprioceptive Stimulation
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- Charles University, Czech Republic
ACL - Anterior Cruciate Ligament Deficiency, Muscle Weakness
Isokinetic Muscular Assessment After ACL Ligamentoplasty: Study of Factors Predictive of Muscle Imbalance.
Despite advances in surgery and rehabilitation, the return to sport after anterior cruciate ligament (ACL) reconstruction surgery remains a major challenge. challenge.
- Trial name
- PREDICT-ACL (NCT04071912)
- Where
- France
- Volunteers
- 113 people
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
The Effect of PEMF for Patients With Quadriceps Muscle Weakness After ACLR
In Hong Kong, over 3000 Anterior Cruciate Ligament Reconstructions (ACLR) are performed each year in order to restore knee function after an ACL injury. The ultimate goal of ACLR is to fulfil the return-to-play (RTP) criteria.
- Trial name
- NCT05184023
- Testing
- Pulse Electromagnetic Field
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Heart Failure
Optoelectronic Pletysmography and Diaphragmatic Thickness in Heart Failure Patients
The investigators aimed to evaluate the effects of cardiomegaly associated with inspiratory muscle weakness on tricompartmental distribution of chest wall volumes, on the thickness of the right hemidiaphragm and on the…
- Trial name
- NCT02481388
- Testing
- Maximal exercise ramp test
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Universidade Federal de Pernambuco
Statin Intolerance
Effects of Epicatechin on Statins for Mitochondrial Dysfunction and Impaired Exercise Capacity
The purpose of this study is to gain insight into the side-effects of statin consumption, and assess the ability of epicatechin (a compound in dark chocolate) to counteract or reverse these changes.
- Trial name
- NCT02490527
- Testing
- Pure epicatechin capsules (50mg), Simvastatin (40mg)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Cerebral Palsy, Weakness
Use of Surface Electromyography Biofeedback to Improve Reaching in Children With Cerebral Palsy
A newly-developed device for biofeedback of surface EMG will be used to either increase or decrease activity in the muscles of children with poor reaching due to cerebral palsy.
- Conditions
- Cerebral Palsy, Weakness, Hypertonia
- Trial name
- NCT00473161
- Testing
- surface EMG biofeedback
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Southern California
Muscle Weakness, XLH
Muscle Abnormalities in Children With XLH
XLH rickets is a rare disease with muscle weakness. Fat parameters such as IMAT and intraMAT could be increased in this disease.
- Trial name
- MDmuscleXLH (NCT05312086)
- Testing
- MRI
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke
THE EFFECT OF SURGICAL MASK AND N95 MASK USE ON SURGICAL SMOKE IN OPERATING ROOM NURSES
This study was conducted to compare the effect of surgical mask and N95 mask use on physical symptoms due to surgical smoke in operating theatre nurses.
- Conditions
- Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke, Headache, Dizziness
- Trial name
- NCT07404956
- Testing
- Surgical Mask, N95 Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity