Clinical trials: Vitrectomy
Diabetic Retinopathy, Macular Edema
20- Versus 23- Gauge System for Pars Plana Vitrectomy
The aim of the present study is to compare the functional and clinical differences and advantages between a standard operating system and a newly developed even smaller system for pars plana vitrectomy.
- Conditions
- Diabetic Retinopathy, Macular Edema, Postoperative Complications, Vitreous Hemorrhage
- Trial name
- NCT00411970
- Testing
- 20- and 23 gauge vitreoretinal surgery systems
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Cataract, Nuclear Progressive
The Post-Vitrectomy Lenstatin™ Study
To determine the efficacy of Lenstatin™, an over-the-counter nutritional supplement, in inhibiting the progression of nuclear cataract in eyes after pars plana vitrectomy.
- Trial name
- NCT02131194
- Testing
- Lenstatin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Lenstatin LLC
Diabetes Mellitus
Fovea Sparing ILM Peeling in Diabetic Patients
The goal of this clinical trial is to compare between foveal sparing ILM peeling and total ILM peeling in diabetic patients (both type 1 and II) with proliferative diabetic retinopathy (PDR) indicated for pars plana vitrectomy…
- Trial name
- NCT07271719
- Testing
- Pars plana vitrectomy (PPV) with fovea sparing ILM peeling., PPV with total ILM peeling
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- David Nashaat Shafik Fahmy
Macular Edema, Cystoid
Intraretinal Cystoid Changes After Vitrectomy With Membrane Peeling
Aim of the study is to assess the rate of postoperative intraretinal cystoid changes after pars plana vitrectomy with membrane peeling and peribulbar application of triamcinolone acetonide and to examine possible risk factors for…
- Trial name
- NCT04472039
- Testing
- optical coherence tomography (OCT)
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Epiretinal Membrane
Phacoemulsification and 25 Gauge (25G) Vitrectomy Versus Phacoemulsification Only in Idiopathic Epiretinal Membranes
The purpose of the study is to evaluate the difference in Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity, oct retinal thickness and microperimetry in 2 groups of 30 eyes each affected by idiopathic epiretinal…
- Trial name
- NCT01771939
- Testing
- 25-G vitrectomy and phacoemulsification, phacoemulsification (cataract surgery)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
Cataract Extraction
Microincision Versus Smallincision Combined Surgery
The purpose of this study is to compare refractive outcomes after two different types of combined cataract surgery, namely microinscision cataract surgery and smallincision cataract surgery, and sutureless 23-gauge vitrectomy in…
- Trial name
- NCT01198483
- Testing
- Combined Micro- Surgery, Combined Small-Surgery
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Endophthalmitis
Endophthalmitis Post Intravitreal Injections
Intravitreal injection (IVI) is an ophthalmological procedure used worldwide to treat ocular conditions. Its use has been steadily increasing for several years, because this method of drug delivery minimizes systemic exposure and…
- Trial name
- EPIIC (NCT04035369)
- Testing
- Tap and Inject (TAI), Pars Plana Vitrectomy (PPV)
- Where
- Canada
- Volunteers
- 310 people
- Sponsor
- Unity Health Toronto
Endophthalmitis, Cataract
Early Vitrectomy for Endophthalmitis After Cataract Surgery
Post-operative infectious endophthalmitis is devastating condition that causes a diffuse intraocular inflammation and may lead to blindness.
- Conditions
- Endophthalmitis, Cataract, Vitreous Detachment, Retinal Detachment
- Trial name
- NCT05249413
- Testing
- Early 23-gauge pars-plana vitrectomy
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- Benha University
Macular Holes, Intraocular Lens Opacification
Oral Sedation in Vitreoretinal Surgery
The purpose of this study is to compare the efficacy of oral sedation to intravenous sedation with anesthesiology support and monitoring.
- Conditions
- Macular Holes, Intraocular Lens Opacification, Vitrectomy, Vitreous Hemorrhage
- Trial name
- NCT04346095
- Testing
- Oral Sedatives with or Without Analgesia, Intravenous Sedatives with or Without Analgesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rocky Vista University, LLC
Retinal Disease, Diabetic Retinopathy
Pain During Pars Plana Vitrectomy With Sub-tenon Anesthesia
Vitreoretinal surgery has evolved to less invasive procedures, and it is used to treat a wide range of diseases. So anesthesia for vitreoretinal procedures has evolved, promoting adequate analgesia while reducing risks to the…
- Conditions
- Retinal Disease, Diabetic Retinopathy, Maculopathy
- Trial name
- NCT03902925
- Testing
- Topical lidocaine 2% jelly plus sub-tenon ropivacaine 10% injection, Peribulbar injection
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- University of Sao Paulo
Eye Diseases
Next Generation Ophthalmic Irrigating Solution Posterior Segment Study
The purpose of this study is to evaluate the safety of Next Generation Ophthalmic Irrigating Solution (NGOIS) compared to BSS PLUS for use during surgery for removal of epimacular membrane and vitrectomy.
- Trial name
- NCT00333203
- Testing
- Next Generation Ophthalmic Irrigating Solution (NGOIS), BSS Plus
- Where
- United States
- Volunteers
- 369 people
- Sponsor
- Alcon Research
Posterior Synechiae of Iris
Mydriatic Drops After Combined Surgery
The study goal is to evaluate the influence of mydriatic drops on the development of posterior synechia after combined cataract and vitrectomy surgery.
- Trial name
- NCT05614622
- Testing
- Cyclopentolate Hydrochloride 1.0% eye drops
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Any Patients Undergoing Vitrectomy Under Local Anaesthesia
The Effect of Preoperative Counseling on Patient Fear From Visual Experience During Vitrectomy Surgery Under Regional Anesthesia
This RCT aims to study the effect of preoperative counselling in reducing patients fear and visual perception during vitrectomy under local anaesthesia.
- Trial name
- NCT01383629
- Testing
- Counselling
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- University of Malaya
Submacular Hemorrhage, Ruptured Retinal Arterial Macro Aneurysms
Submacular Hemorrhage Associated With Retinal Arterial Macro Aneurysm
Evaluation of surgical outcome of vitrectomy with subretinal injection of recombinant tissue-plasminogen activator for submacular hemorrhage associated with retinal arterial macroanuerysms.
- Trial name
- NCT02120066
- Testing
- Vitrectomy for submacular hemorrhage, subretinal injection of tissue-plasminogen activator
- Where
- Japan
- Volunteers
- 22 people
- Sponsor
- Kyorin University
Recurrent, Hemorrhage
Adjuvant Intravitreal Bevacizumab in Pars Plana Vitrectomy for Diabetic Vitreous Hemorrhage
Postoperative vitreous hemorrhage is a common complication after vitrectomy for proliferative diabetic retinopathy. There have been efforts to lower the incidence of postoperative vitreous hemorrhage such as preoperative…
- Trial name
- ABeVi (NCT01151722)
- Testing
- bevacizumab injection
- Where
- Brazil
- Volunteers
- 2 people
- Sponsor
- University of Sao Paulo
Retinal Vein Occlusion
Radial Optic Neurotomy in Central Retinal Vein Occlusion : a Randomized Trial
Natural evolution of severe central retinal vein occlusion with low visual acuity is very poor. A randomized clinical trial will compare troxerutin and platelet anti-aggregating agents (drug treatment) versus surgery and drug…
- Trial name
- OVCR (NCT00379223)
- Testing
- vitrectomy with radial optic neurotomy
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Bordeaux
Vascular Retinopathy of Left Eye (Disorder), Vascular Retinopathy of Right Eye (Disorder)
Intraoperative Application of Fluorescein Sodium Angiography in Vascular Retinopathy
The study used a new surgical technique: intraoperative fluorescence imaging,In the 1980s, some scholars proposed the concept of intraoperative fluorescein angiography.During vitrectomy, intraoperative fluorescein angiography…
- Conditions
- Vascular Retinopathy of Left Eye (Disorder), Vascular Retinopathy of Right Eye (Disorder), Diabetic Retinopathy, Retinal Vein Occlusion
- Trial name
- NCT06343961
- Testing
- Intraoperative Fluorescein Angiography
- Volunteers
- 80 people
- Sponsor
- Jie Zhong
Epiretinal Membrane, Macular Edema (ME)
Minimal Vitrectomy Surgery for Epiretinal Membrane
This multicenter randomized controlled trial evaluates Minimal Vitrectomy Surgery (MVS) versus conventional vitrectomy for idiopathic epiretinal membrane (ERM).
- Conditions
- Epiretinal Membrane, Macular Edema (ME), Nuclear Cataract
- Trial name
- MVS-ERM (NCT07019896)
- Testing
- Minimal Vitrectomy Surgery, Conventional Vitrectomy
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Peking Union Medical College Hospital
Rhegmatogenous Retinal Detachment
Perfluorocarbon Liquid vs. Posterior Retinotomy During Pars-plana Vitrectomy for Rhegmatogenous Retinal Detachment
Purpose To evaluate the outcomes of perfluorocarbon liquid (PFCL) versus posterior retinotomy (PR) during Pars plana vitrectomy (PPV) for Rhegmatogenous retinal detachment (RRD), focusing on anatomical success, visual acuity…
- Trial name
- NCT06919211
- Testing
- Perfluorocarbon Liquid vs. Posterior Retinotomy during Pars-plana Vitrectomy for The Surgical Repair of Rhegmatogenous Retinal Detachment
- Where
- Egypt
- Volunteers
- 29 people
- Sponsor
- Benha University
Retinal Detachment, Vitrectomy
Comparative Study of 1000 Centistoke Versus 5000 Centistoke Silicone Oil for Repair of Complex Retinal Detachments
The purpose of this study is to assess the retinal redetachment rates with 1000 centistoke versus 5000 centistoke silicone oil tamponade for repair of complex retinal detachments.
- Conditions
- Retinal Detachment, Vitrectomy, Proliferative Vitreoretinopathy, Diabetic Retinopathy
- Trial name
- NCT01255293
- Testing
- 1000 centistoke silicone oil, 5000 centistoke silicone oil
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mid Atlantic Retina