Clinical trials: Vital Sign Evaluation, open to volunteers
CAD-CAM, Prospective Study
Clinical Evaluation of Additive and Subtractive Onlay Restorations
The goal of this clinical trial is to learn whether onlay restorations produced by additive manufacturing [three-dimensional (3D) printing] and subtractive manufacturing [Computer-Aided Design/Computer-Aided Manufacturing…
- Conditions
- CAD-CAM, Prospective Study, 3D Printing, Clinical Assessment
- Trial name
- CIP-ONLAY (NCT07195201)
- Testing
- 3D Printed Onlay Restoration, CAD/CAM Onlay Restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Ayse Tugba Erturk Avunduk
Deep Carious Lesions
Clinical Performance of Resin Composite Restoration After Dentin Biomodification by Grape Seed Extract in Deep Carious Lesions.
This study will evaluate the clinical and radiographic performance of resin composite restoration after utilized a grape seed extract as dentin biomodification in vital teeth with deep occlusal carious lesions (ICDAS 5-6) after…
- Trial name
- GSE (NCT06780527)
- Testing
- 15% Grape seed extract as dentin pretreatment
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Non Vital Teeth, Persistent Symptomatic Apical Periodontitis
To Evaluate and Compare the Effect of Orthograde and Retrograde MTA Root End Filling After Periapical Surgery in Posteriors
To evaluate and compare the effect of orthograde and retrograde MTA root end filling on clinical, 2D and 3D radiographic success and quality of life after periapical surgery in posteriors- A Randomised Control Trial
- Trial name
- NCT07808424
- Testing
- Endodontic Micro-Surgery
- Where
- India
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pulpitis - Reversible, Pulpotomy
Clinical and Radiographic Evaluation of Chitosan Versus Formocresol After Vital Pulpotomy of Primary Molars
The goal of this clinical trial is to evaluate whether Chitosan liquid will show similar clinical and radiographical success rate compared to Formocresol when used in vital pulp therapy in primary molars.
- Trial name
- NCT06809478
- Testing
- Pulpotomy using Chitosan liquid, Pulpotomy using Formocresol
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Coronary Angiography (CAG)
Effect of Foot Massage After Coronary Angıography on Back Paın and Vıtal Sıgns
The aim of the study was to evaluate the effect of foot massage on patients' back pain and vital signs after coronary angiography. It is important for the transfer of nonpharmacological methods to clinical applications
- Trial name
- NCT06779955
- Testing
- foot massage application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- ayşenur kahveci
Pulptomy, Dental Caries
Effect of Ferric Sulphate and Putty MTA as Pulpotomy Agent in Vital Primary Teeth
The pulp in primary teeth has a high potential for repair because of high degree of cellularity and vascularity. The rationale for the pulpotomy procedure is that the radicular pulp tissue is healthy and capable of healing after…
- Conditions
- Pulptomy, Dental Caries, Pulp Therapy
- Trial name
- CT (NCT07324928)
- Testing
- Ferric sulphate, Putty MTA
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Jazan
Irreversible Pulpitis, Primary Teeth
Comparison of 3Mixtatin Pulpotomy and Metapex Pulpectomy in Primary Molars With Irreversible Pulpitis
The present study aims to evaluate the clinical and radiographic success of pulpotomy using 3Mixtatin versus pulpectomy using Metapex in primary molars with irreversible pulpitis in children aged 4 to 9 years.
- Conditions
- Irreversible Pulpitis, Primary Teeth, Pulp Disease, Dental
- Trial name
- NCT06925490
- Testing
- Metapex, 3Mixtatin
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Complication, Respiratory Complications
Real-time Evaluation and Continuous Observation of Vital Signs for Enhanced Recovery: a Study for the Early Identification of Complications in the Surgical Ward Following Surgery in Patients Not Eligible for Intensive Care Admission.
This study aims to evaluate whether continuous vital sign monitoring with wearable devices can help detect postoperative complications in surgical ward earlier than standard hospital monitoring.
- Conditions
- Postoperative Complication, Respiratory Complications, Cardiac Complications
- Trial name
- RECOVER (NCT07729891)
- Testing
- Continuous vital sign monitoring with Portrait Mobile in surgical ward
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
MTA Vital Tooth Pulpotomy
Clinical & Radiographic Efficacy Using LLLT & CRYO on M.P.M Pulpotomy
This in-vivo study aims to evaluate the efficacy of the low level laser therapy and cryotherapy in treatment of vital pulpotomy in mature permanent molar evaluating the post operative pain and the radiographic changes in pulpal…
- Trial name
- NCT06711081
- Testing
- low level laser device cryotherapy
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Vital Pulp Therapies, Pulpotomy
Clinical and Radiographic Evaluation of Potassium Nitrate in Polycarboxylate Versus Mineral Trioxide Aggregate in Vital Pulpotomy in Primary Molars
The purpose of this RCT is to compare the clinical/radiographic outcomes of Potassium nitrate in polycarboxylate cement and MTA as pulpotomy biomaterials used for asymptomatic vital primary lower second molar and this will help…
- Conditions
- Vital Pulp Therapies, Pulpotomy, Pulp Disease, Dental, Pulpotomies Primary Teeth
- Trial name
- NCT06871709
- Testing
- Potassium Nitrate in Polycarboxylate cement, MTA-Anglus
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulmonary Arterial Hypertension
A Trial of "APL-9796'' in Adults With Pulmonary Hypertension
The AP13CP02 study is a phase 2, open-label, dose escalation trial to determine how safe and tolerable multiple subcutaneous (SC) injections of APL-9796 are for patients with PH.
- Trial name
- ViTAL-PH (NCT06846554)
- Testing
- APL-9796
- Where
- 6 sites in United Kingdom
- Volunteers
- 48 people
- Sponsor
- Apollo Therapeutics Ltd
Vital, Pulpotomy
Clinical and Radiographic Evaluation of Vital Pulpotomy Techniques in Primary Molars Using of Premixed Bioactive Bioceramic MTA (Neo-putty) as a Novel Pulpotomy Medication Versus Formocresol
Despite the benefit of formocresol, there are toxic effects allergic reactions and local soft and hard tissue necrosis have been reported when such formaldehyde compounds were used clinically, however, the adverse effect of the…
- Conditions
- Vital, Pulpotomy, Techniques
- Trial name
- NCT06288477
- Testing
- A cotton pellet moistened with full-strength FC, Neo-Putty
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Pulpotomies Primary Teeth, Pulp Disease, Dental
Clinical and Radiographic Evaluation of Hyaluronic Acid (Gengigel Teething) Versus Mineral Trioxide Aggregate( Angelus) as Pulpotomy Agent in Vital Primary Molars
The goal of this clinical trial is to Clinical and Radiographic Evaluation of Hyaluronic Acid (Gengigel Teething) Versus Mineral Trioxide Aggregate( Angelus) as Pulpotomy Agent in Vital Primary Molars.
- Trial name
- HA - MTA (NCT06611631)
- Testing
- Hyaluronic acid pulpotomy, mineral trioxide aggregate pulpotomy
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Post-operative Pain, Pulpitis - Irreversible
Outcomes of Pulpotomy and Root Canal Treatment in Teeth With Symptomatic Irreversible Pulpitis
The aim of this study is to evaluate the clinical effectiveness of total pulpotomy (TP), radicular pulpotomy (RP), and root canal treatment (RCT) in mandibular premolar and/or molar teeth diagnosed with symptomatic irreversible…
- Conditions
- Post-operative Pain, Pulpitis - Irreversible, Success Rate
- Trial name
- NCT07375576
- Testing
- Total Pulpotomy, Radicular pulpotomy, Root canal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Pain, Postoperative, Root Resorption
Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair
Management of non-vital primary molars is challenging due to the natural anatomy of primary teeth, patients' young age, and their behavior toward dental treatment.
- Conditions
- Pain, Postoperative, Root Resorption, Persistent Infection, Necrotic Pulp
- Trial name
- NCT06926322
- Testing
- Conventional double antibiotic paste of Metronidazole 500 mg plus Ciprofloxacin 500 mg mixed with propylene glycol, Double antibiotic paste of Metronidazole and Ciprofloxacin loaded chitosan-coated silver nanoparticles, chitosan-coated silver nanoparticles
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Sleep, Cognition
Sleep Apnea and Cognition in Older Adults
The goal of this cross-sectional, observational, medical device trial is to examine the association of several sleep parameters, including specific respiratory events and an apnea-hypopnea index, with cognitive performance in…
- Conditions
- Sleep, Cognition, Aging
- Trial name
- NCT06423118
- Testing
- ANNE Vital Sign System
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Tooth Discoloration, Tooth Staining
Effectiveness of Dental Bleaching Using Different Designs of 3D-Printed and Conventional Customized Nightguards
This randomized, double-blind, split-mouth clinical trial evaluates the effectiveness of at-home dental bleaching using customized nightguards fabricated by digital (3D-printed CAD-CAM) and conventional methods, with and without…
- Trial name
- NCT07464197
- Testing
- Customized bleaching tray fabrication, Reservoir tray design, Carbamide peroxide 10%
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Progressive Fibrosing Interstitial Lung Disease (PF-ILD) / Progressive Pulmonary Fibrosis (PPF)
A Study to Explore the Therapeutic Effect of HEC585 on Delaying Forced Vital Capacity (FVC) Decline and Tolerance in Progressive Fibrosing Interstitial Lung Disease (PF-ILD) Patients
The main goal of this phase llb study is to compare the efficacy and safety of two doses of HEC585 tablets with placebo which is a look-alike substance that contains no active drug in patients with progressive fibrosing…
- Trial name
- NCT05139719
- Testing
- HEC585 dose A, HEC585 dose B
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
Pulp Disease, Dental, Pulp Therapy in Primary Molars
Oxymetazoline Versus Sodium Hypochlorite as Hemostatic Agents in MTA Pulpotomy of Primary Molars
This study aims to evaluate clinical and radiographic success of oxymetazoline versus sodium hypochlorite as hemostatic agents in MTA pulpotomy of primary molars.
- Conditions
- Pulp Disease, Dental, Pulp Therapy in Primary Molars, Pulpitis - Reversible, Pulp Inflammation
- Trial name
- OXY - MTA (NCT07675330)
- Testing
- Oxymetazoline 0.05% nasal solution, Sodium Hypochlorite Solution
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Postoperative Care, Deterioration, Clinical
Optimized Novel Wireless Assessment of Respiratory and Circulatory Dirstress - Alarm Validation
The ONWARD study evaluates user experiences from continuous vital sign monitoring alarms sent to the clinical staff in case of deviating vital signs at the general hospital ward.
- Trial name
- ONWARD - AV (NCT07649642)
- Testing
- Continuous vital sign monitoring
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Eske Kvanner Aasvang