Clinical trials: Visual Perception
Glaucoma and Ocular Hypertension, Diabetic Macular Edema
Effect of Dexamethasone Implant on Optic Disc
This study evaluates the effect of dexamethasone implant which is an intraocular corticosteroid on the optic nerve fibers. Retinal nerve fiber thicknesses and optic nerve head pitting rates were measured before and 6 months after…
- Conditions
- Glaucoma and Ocular Hypertension, Diabetic Macular Edema, Intravenous Drug Usage, Optic Disk Disorders
- Trial name
- NCT03927118
- Testing
- intravitreal dexamethasone implant application
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Strabismus
Adjustable Strabismus Surgery
Strabismus, whether congenital or acquired, is a common visual and cosmetic problem, especially for the young. Adjustable suture strabismus surgery is not in vogue in our country.
- Trial name
- NCT05425589
- Testing
- Adjustable strabismus surgery
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Corticobasal Syndrome(CBS), Primary Progressive Aphasia(PPA)
Neuroinflammation in FTLD
The goal of this observational study is to investigate the role of neuroinflammation in frontotemporal lobar degeneration (FTLD). The main aims of this study are: 1.
- Conditions
- Corticobasal Syndrome(CBS), Primary Progressive Aphasia(PPA), Progressive Supranuclear Palsy(PSP), Behavioral Variant Frontotemporal Dementia (bvFTD)
- Trial name
- NCT06870838
- Testing
- 7T MRI scan, CSF, Blood withdrawal
- Where
- 2 sites in Netherlands
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Amblyopia, Strabismus
Improving Quality Vision Outcomes in Managed Care Setting While Reducing Cost by Use of Accurate, Automated Screening
Amblyopia ("lazy eye") and strabismus (misaligned eyes) are medical eye conditions that combine as the leading causes of preventable vision loss in children.
- Trial name
- NCT02536963
- Testing
- Pediatric Vision Scanning device, Reference examination
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Dry Eye, MGD-Meibomian Gland Dysfunction
Study on Prevention and Treatment of Dry Eye in Patients Using Glaucoma Drops
A multicenter randomized controlled trial on prevention and treatment of ocular surface injury and meibomian gland dysfunction in patients using anti-glaucoma eye drops.
- Trial name
- NCT03515187
- Testing
- 0.3% sodium hyaluronate ophthalmic solution, 0.1% sodium bromide solution, Meibomian gland massage
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Shenzhen Hospital of Southern Medical University
Cataract, Traffic Accident
Validation of Mesopic and Photopic Contrast Vision Tests With Respect to Nighttime Driving Ability
A) The main purposes of this study are (i) to develop a related virtual reality (VR) environment in order to judge the nighttime driving ability under mesopic and under glare conditions (ophthalmologically healthy subjects and…
- Conditions
- Cataract, Traffic Accident, Vision Disorders, Driving Impaired
- Trial name
- ContrastVal (NCT03169855)
- Testing
- Slit lamp (LOCS III Score)
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Aalen University
Quality of Life (QOL), Anxiety
Testing the Efficacy of the "Syd" App on Improving Quality of Life and Mental Health Among University Students in the Kingdom of Saudi Arabia
The goal of this clinical trial is to learn if using the "See Yourself Differently" (syd) app can help improve quality of life and mental health for university students in Saudi Arabia.
- Conditions
- Quality of Life (QOL), Anxiety, Stress, Affect (Mental Function)
- Trial name
- NCT06979778
- Testing
- See Yourself Differently (syd) mobile app
- Where
- Saudi Arabia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- iamYiam Limited
Cataract, Healthy
Dynamic Light Scattering Device (DLS) Study of Age-Related Changes in the Lens and Cataracts
This study will use a newly developed instrument called dynamic light scattering device (DLS) to examine age-related changes in the human lens and to study the causes and development of cataracts.
- Trial name
- NCT00007215
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Dry Eye
Preliminary Clinical Study of the Effectiveness and Safety of Ocular Surface Microbiota Transplantation in the Treatment of Dry Eye Disease
Evaluate the efficacy and safety of ocular surface microbiota transplantation as an adjunctive therapy for dry eye, and explore its impact on the structure of the ocular surface microbiota.
- Trial name
- NCT07298811
- Testing
- Ocular surface microbiota transplantation
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Pseudoexfoliation Syndrome, Pseudoexfoliation Glaucoma in Both Eyes
Correlation Between Pupil Size and Ocular Signs of Pseudoexfoliation Syndrome
To study possible correlation between the size of the pupil in both room light and after dilation between both eyes in bilateral pseudoexfoliation with Intraocular pressure, lens clarity and stability, Optic disc , Visual changes…
- Conditions
- Pseudoexfoliation Syndrome, Pseudoexfoliation Glaucoma in Both Eyes, Pseudoexfoliation of Lens; Glaucoma
- Trial name
- NCT05113121
- Testing
- , Humphrey visual field (24-2) analysis and optical coherence tomography on retinal nerve fiber layer (RNFL) and ganglion cell complex.(GCC)
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Smoking Cessation
Cognitive-Behavioral Therapy and Hypnotherapy for Smoking Cessation
Intensive cognitive-behaviour interventions (CBT) combined with pharmacotherapy for smoking cessation are well established and have been proved to be efficacious.
- Trial name
- CBT-HT (NCT01129999)
- Testing
- Cognitive-Behavioral Therapy, Hypnotherapy
- Where
- Germany
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Young Healthy Adults, Healthy
Study of Visual Mecanisms Involved in Face Recognition
Since the 19th century, perception has been regarded as an inferential process in which sensory input is compared with prior knowledge, namely the internalised representation of the visual environment.
- Trial name
- HUMVIS (NCT06851923)
- Testing
- 3Tesla magnetic resonance imaging of the healthy human visual system
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Primary Open Angle Glaucoma
STudy to Assess Rapid Disease Progression by Clinical and Genetic Factors In Glaucoma patientS That Are High Risk
The purpose of this study is to perform exploratory analyses to evaluate rates of functional and structural change in glaucoma, to identify predictors of rapid progression in patients with glaucoma and to identify possible…
- Trial name
- STARFISH (NCT01442896)
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Visual Acuity Reduced Transiently
Changes in Power and Cylinder Axis of Toric Soft Contact Lenses (LKL)
Astigmatism is a common refractive error resulting from a toric-surfaced cornea which using a toric soft contact lens could be one of the therapy options.
- Trial name
- NCT04724525
- Testing
- soft contact lens Toric
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Stevens-Johnson Syndrome, Toxic Epidermal Necrolyses
Meibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis
The investigators' aim is to study the effects of mechanical expression of meibomian glands on eyelid disease, ocular surface health in the subacute phase of SJS/TEN.
- Conditions
- Stevens-Johnson Syndrome, Toxic Epidermal Necrolyses, Ocular Surface Disease, Meibomitis
- Trial name
- NCT05145959
- Testing
- Maskin Probe
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Glaucoma Diagnosis
How Accurately Does the Diopsys Visual Evoked Potential (VEP) Vision Testing System Detect Glaucoma?
Evaluate sensitivity and specificity of NOVA-DN visually evoked potentials (VEP) protocol and new software method (Corda) for glaucoma detection using optical coherence tomography (OCT) images to differentiate between normal…
- Trial name
- NCT02622178
- Testing
- Optical Coherence Tomography, Visual evoked potential
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Dry Eye
Clinical Trial to Evaluate the Safety and Tolerability of Lagricel® Ofteno Multi-dose Ophthalmic Solution
Study design: Phase I clinical trial, single-center, controlled, parallel group, open, randomized. Number of subjects: n = 34 evaluable subjects, 17 evaluable subjects per group (both eyes).
- Trial name
- PRO-037 (NCT04081610)
- Testing
- lagricel ofteno multidose, lagricel ofteno single dose
- Where
- Mexico
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Glaucoma, Ocular Hypertension
A Phase I Clinical Trial of DARC
Glaucoma is a major cause of irreversible blindness worldwide, caused by retinal nerve cell (RGC) death. This is currently identified only after significant vision loss has already occurred with an early event in, and a potential…
- Conditions
- Glaucoma, Ocular Hypertension, Glaucoma, Suspect
- Trial name
- NCT02394613
- Testing
- ANX776
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University College, London
Allergic Conjunctivitis
Evaluation of Efficacy of Ophthalmic Solution in Induced Allergic Conjunctivitis
The purpose of this study is to establish the efficacy of R89674 0.25% ophthalmic solution compared with placebo in alleviating the signs and symptoms of conjunctival allergen challenge-induced allergic conjunctivitis
- Trial name
- NCT00244543
- Testing
- R89674 (generic name not yet established)
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Vistakon Pharmaceuticals
Regional Blood Flow, Ocular Physiology
Effects of Moxaverine and Placebo on Ocular Blood Flow
A number of common eye diseases such as retinal artery and vein occlusion, diabetic retinopathy, age-related macular degeneration, glaucoma and anterior ischemic optic neuropathy are associated with ocular perfusion…
- Conditions
- Regional Blood Flow, Ocular Physiology, Retina
- Trial name
- NCT00709423
- Testing
- Moxaverine, Moxaverin 150mg, NaCl
- Where
- Austria
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna