Clinical trials: Visual Acuity
Visual Acuity
A Comparison of Two Daily Disposable Soft Contact Lenses
Approximately 120 subjects will be comparing two soft contact lenses for one week each.
- Trial name
- NCT02427477
- Testing
- senofilcon A, delefilcon A
- Where
- 6 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Visual Performance of Soft Contact Lenses With Myopia Control Optics
This is a multi-site, bilateral, dispensing, randomized, controlled, single-masked, 3x3 crossover study with a run-in period.
- Trial name
- NCT05141448
- Testing
- 1-Day Acuvue Moist, EMO-118, EMO-114
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Dry Age-related Macular Degeneration
Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITE III)
This LIGHTSITE III study is a double-masked, sham-controlled, parallel design, prospective multi-site study for the use of PBM as a treatment for visual impairment in subjects with dry AMD.
- Trial name
- NCT04065490
- Testing
- Valeda Light Delivery System
- Where
- 10 sites in United States
- Volunteers
- 100 people
- Sponsor
- LumiThera, Inc.
Visual Acuity
Clinical Evaluation of Senofilcon A Contact Lenses Using a Novel Manufacturing Technology to Evaluate Overall Visual Acuity.
This study is a feasibility, multi-site, randomized, double-masked, 2-arm parallel group design, 2-week dispensing study with weekly visits to evaluate visual acuity.
- Trial name
- NCT05361304
- Testing
- senofilcon A contact lenses made with a novel manufacturing technology, senofilcon A contact lenses made with the current manufacturing technology
- Where
- 6 sites in United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of Investigational Daily Disposable Multifocal Contact Lenses Produced With Different Manufacturing Processes in Myopes
This is a single-masked, 2×3 crossover, randomized controlled, dispensing clinical trial to evaluate the visual performance (logMAR) and subjective vision responses of the Test Lens.
- Trial name
- NCT04889625
- Testing
- senofilcon A C3, Dailies Total 1® Multifocal Contact Lenses
- Where
- 6 sites in United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of a Toric Multifocal Contact Lens Manufactured in Etafilcon Material in a Low ADD Hyperopic Population
The study is a bilateral, single-masked, single-arm, 3-visit dispensing study. There will be one study treatment, with the subject being in the treatment for approximately 12-16 days.
- Trial name
- NCT03713281
- Testing
- Toric Multifocal etafilcon A with PVP
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluating Visual Acuity and Initial Fit Performance of Two Soft Contact Lenses
This is a multi-center, randomized, controlled, double-masked, 2x2 cross-over, non-dispensing study to compare visual acuity and lens fit performance.
- Trial name
- NCT04954833
- Testing
- EMO-200, EMO-118
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of Senofilcon A Contact Lenses Using a Novel Manufacturing Technology
This study is a multi-site, randomized, double-masked, 2×2 crossover design, 1-week dispensing study. Subjects will wear bilaterally both Test and Control lenses in a random order for 1-week each as a daily disposable modality…
- Trial name
- NCT04531241
- Testing
- ACUVUE® OASYS 1-DAY
- Where
- 7 sites in United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of Investigational Contact Lenses
Single-visit, unmasked, non-dispensing study where subjects will wear three different lenses bilaterally in one visit, each lens being worn for approximately 30-60 minutes.
- Trial name
- NCT02801396
- Testing
- Etafilcon A Design 1 (Test 1), Etafilcon A Design 2 (Test 2), Etafilcon A (Control)
- Where
- Hong Kong
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of Senofilcon A With New UV-blocker on a Neophyte Population
This is a 5-visit, single-arm, open-label, dispensing study. Each subject will be bilaterally fit with the test article for approximately 4 weeks of reusable daily wear with lens replacement occurring 2-weeks after initial…
- Trial name
- NCT03742271
- Testing
- senofilcon A
- Where
- 11 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of Rotation With a Multifocal Toric Contact Lens
The study is a bilateral, single-masked, single-visit, non-dispensing 2x2 crossover study to confirm a finalized design of a prototype contact lens.
- Trial name
- NCT05433571
- Testing
- Test Lens
- Where
- 5 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Design Validation of Senofilcon A With New UV-blocking Additive
This is a 2-visit, multi-site, partially subject-masked, 2-arm parallel, controlled, randomized and dispensing trial. Subjects will be randomized to one of two study lenses for the entire duration of the study.
- Trial name
- NCT03707821
- Testing
- senofilcon A TEST Lens, senofilcon A CONTROL Lens
- Where
- 10 sites in United States
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Late Night Study 2: End-of-Day Assessment of Asymptomatic and Symptomatic Soft Lens Wearers
This is a 2-Part, 8-Visit, single-center, open-label, bilateral and dispensing clinical study. In Part 1 (Visits 1-4) all subjects will be Test Lens 1, in Part 2 (Visits 1-4) eligible subjects will be dispensed Test Lens 2 based…
- Trial name
- NCT03871543
- Testing
- AquaComfort Plus, Acuvue Oasys 1-Day
- Where
- United Kingdom
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Age-related Macular Degeneration, Polypoidal Choroidal Vasculopathy
Visual Outcome in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy (PCV) Treated With Either Ranibizumab as Monotherapy or Combined With Verteporfin Photodynamic Therapy (vPDT)
This study compared the effect of ranibizumab administered as monotherapy versus ranibizumab administered in combination with verteporfin photodynamic therapy (PDT) on visual acuity in patients with symptomatic macular polypoidal…
- Trial name
- EVEREST II (NCT01846273)
- Testing
- Ranibizumab, Verteporfin PDT
- Where
- 41 sites in Hong Kong, Japan and 5 more
- Volunteers
- 321 people
- Sponsor
- Novartis Pharmaceuticals
Visual Acuity
Influence of Lens Design on Particulate Exchange in the Post-lens Tear Film
This is a 5-visit, controlled, bilateral, randomized, subject-masked, crossover (4 treatments x 4 period), non-dispensing study.
- Trial name
- NCT03782571
- Testing
- etafilcon a Test 1, etafilcon A Test 2, etafilcon A Test 3
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of Visual Performance of Two Types of Cosmetic Contact Lenses
This is a single visit, brand-masked, non-dispensing, 2×2 bilateral crossover study. Each subject will be bilaterally fitted with one of the two test articles in each of the study periods in a random order with a 5-minute washout…
- Trial name
- NCT04534764
- Testing
- etafilcon A with cosmetic pattern, 1-Day Acuvue DEFINE Vivid Style
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of Astigmatic Contact Lenses
Randomized, double-masked, 5-visit, bilateral dispensing, parallel group study to demonstrate that the investigational contact lens meets the design requirements related to corneal staining, lens fit, visual acuity and rotational…
- Trial name
- NCT03086447
- Testing
- Investigational Contact Lens, Marketed Contact Lens
- Where
- 17 sites in United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Macular Edema
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Participants With Diabetic Macular Edema
The study will be composed of 3 periods for all participants: Screening, 28-day Treatment period, and Follow-up visit (approximately 28 days after the final dose).
- Trial name
- NCT04292912
- Testing
- GSK2798745
- Where
- 11 sites in United States, Australia and 1 more
- Volunteers
- 16 people
- Sponsor
- GlaxoSmithKline
Visual Acuity
Temporal Interference Brain Stimulation
The primary aim of this study is to translate temporal interference (TI) stimulation methodology into humans and examine its safety, feasibility, steerability, and focality.
- Trial name
- TI (NCT03747601)
- Testing
- Temporal Interference (TI) Stimulation
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Visual Acuity
Clinical Evaluation of Two Approved Contact Lenses
Adaptive, randomized, subject-masked, dispensing study to evaluate the short-term, clinical performance of two FDA-approved contact lens.
- Trial name
- NCT02759692
- Testing
- TEST Contact Lens, CONTROL Contact Lens
- Where
- 13 sites in United States
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.