Clinical trials: Visual Acuity
Visual Acuity
Effects of Multifocal Contact Lens on Ocular Tissue
The purpose of this study is to evaluate the etafilcon - PVP (multi-focal)
- Trial name
- NCT02345720
- Testing
- etafilcon - PVP (multi-focal)
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Choroidal Neovascularization Secondary to Pathologic Myopia
A Study of the Criteria Establishing the Need for Re-treatment With Ranibizumab Upon Relapse in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia.
The primary objective of the study was to investigate current criteria driving re-treatment in patients affected by Choroidal Neovascularization (CNV) secondary to Pathologic Myopia (PM) and experiencing a relapse of the disease…
- Trial name
- OLIMPIC (NCT02034006)
- Testing
- Ranibizumab
- Where
- 31 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Novartis Pharmaceuticals
Age - Related Macular Degeneration (AMD)
Study to Assess Best Corrected Visual Acuity (BCVA) in Patients With Neovascular Age-Related Macular Degeneration (AMD) Who Are Administered VEGF Trap-Eye (Intravitreal Aflibercept Injection)
This is a phase 4, open-label, single arm, multicenter, clinical study in patients with neovascular AMD designed to evaluate the efficacy and safety of Intravitreal Aflibercept Injection (IAI) administered over 2 years , and to…
- Trial name
- RE-VIEW (NCT01722045)
- Testing
- Intravitreal Aflibercept Injection (IAI)
- Where
- 49 sites in United States
- Volunteers
- 154 people
- Sponsor
- Regeneron Pharmaceuticals
Diabetes Mellitus, Macular Edema
Intravitreal Aflibercept Injection in Vision Impairment Due to DME
To determine the efficacy of intravitreally (IVT) administered VEGF Trap-Eye on the best-corrected visual acuity (BCVA) assessed by the early treatment diabetic retinopathy study (ETDRS) chart in subjects with diabetic macular…
- Trial name
- VIVID-DME (NCT01331681)
- Testing
- VEGF Trap-Eye (BAY86-5321), Macular Laser Photocoagulation (Control)
- Where
- 73 sites in Australia, Austria and 9 more
- Volunteers
- 406 people
- Sponsor
- Bayer
Visual Acuity
Comparison of a Daily Disposable Multifocal Contact Lens to a Marketed Product
This is a single-masked, two-arm, parallel-group, randomized-controlled, dispensing clinical trial to evaluate the visual performance.
- Trial name
- NCT05101252
- Testing
- senofilcon A C3, Dailies Total 1 Multifocal Contact Lenses
- Where
- 9 sites in United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of Investigational Multifocal Contact Lenses
3-visit dispensing study to evaluate the subjective feedback of a multifocal contact lens in a population of presbyopic patients. Subjects will wear the contact lenses for a total of 12-16 days.
- Trial name
- NCT03059810
- Testing
- etafilcon A
- Where
- 9 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Marketed Contact Lens Real World Through Focus Curve
This is a single-visit prospective study to establish a real world Marketed Contact Lens 'Through Focus Curve' (TFC) measurement by comparing the consistency of vision between myopes and hyperopes.
- Trial name
- NCT02679976
- Testing
- etafilcon A
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of a Daily Wear Reusable Multifocal Optical Design in a Presbyopic Population
The clinical study is a bilateral, single-masked (partial), single-arm, clinical trial. A total of approximately 60 eligible subjects both near-sighted and far-sighted, will be targeted to complete the study.
- Trial name
- NCT04534517
- Testing
- JJV Investigational Multifocal Contact Lens, ACUVUE OASYS® with HYDRACLEAR® PLUS
- Where
- 11 sites in United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error
Clinical Performance of a Silicone Hydrogel for Daily Disposable Wear
The purpose of this study is to compare the visual acuity of an investigational silicone hydrogel to a commercially available silicone hydrogel in contact lens wearers.
- Trial name
- NCT03095027
- Testing
- FID122819 contact lenses, Stenfilcon A contact lenses
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- Alcon Research
Wet Age Related Macular Degeneration
Safety and Tolerability of Ranibizumab in Mono/Bilateral Wet Age Related Macular Degeneration (w-AMD) Patients in Eyes With BCVA<2/10 and/or 2nd Affected Eye
The purpose of this study is to evaluate the safety and efficacy of ranibizumab in patients affected by wet age related macular degeneration (wAMD).
- Trial name
- TWEYES (NCT01986907)
- Testing
- ranibizumab
- Where
- 101 sites in Italy
- Volunteers
- 1,049 people
- Sponsor
- Novartis Pharmaceuticals
Corneal Ulcer, Eye Infections, Fungal
Mycotic Ulcer Treatment Trial I
The purpose of this study is to determine if natamycin or voriconazole results in better visual outcomes in fungal corneal ulcers, especially visual acuity.
- Trial name
- MUTT I (NCT00996736)
- Testing
- Natamycin, Voriconazole
- Where
- 3 sites in United States, India
- Volunteers
- 323 people
- Sponsor
- University of California, San Francisco
Vestibular Neuronitis, Vestibular Neuronitis, Bilateral
Recovery of Visual Acuity in People With Vestibular Deficits
The purpose of this study is to determine whether exercises relieve the symptoms of dizziness and imbalance in people with vestibular deficits and improves the ability to see clearly during head movements.
- Conditions
- Vestibular Neuronitis, Vestibular Neuronitis, Bilateral, Vestibular Schwannoma
- Trial name
- NCT00411216
- Testing
- Control exercises, gaze stabilization exercises
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Emory University
Visual Acuity, Astigmatism
LFR-260 vs Traditional Phoropter in Visual Acuity Testing
The purpose of this study is to establish if LFR-260 (investigational device) is not inferior in effectiveness to a traditional phoropter (control device) when applied in visual acuity test in subjects undergoing a full routine…
- Conditions
- Visual Acuity, Astigmatism, Anisometropia
- Trial name
- NCT05259163
- Testing
- LFR-260 portable phoropter, Traditional phoropter (SOC)
- Where
- 2 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Evolution Optiks Limited
Visual Acuity
Clinical Evaluation of Spherical Soft Contact Lenses, Toric Soft Contact Lenses and Spectacles in Low Astigmats
This will be a 5-visit, randomized, partially single-masked, bilateral wear, dispensing, 2-treatment × 2-period crossover study with spectacle-wear washout and wash-in periods.
- Trial name
- NCT05056870
- Testing
- ACUVUE Oasys 1-Day with HydraLuxe Technology for Astigmatism, ACUVUE Oasys 1-Day with HydraLuxe Technology
- Where
- 13 sites in United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Hyperopia
Comparing Low-cost Handheld Autorefractors - a Practical Approach to Measuring Refraction in Low Resource Settings
Study compares four portable vision measurement and eye-imaging technologies in terms of accuracy and time and ease of use with older adult (ages 40-100) participants in a developing-country setting (India).
- Trial name
- NCT03456245
- Testing
- Vision device validation
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Visual Acuity
Clinical Evaluation of a Reusable Multifocal Optical Design in a Presbyopic Population Phase 2
This is a single-masked, randomized-controlled, dispensing clinical trial. A total of approximately 60 eligible hyperopic subjects will be targeted to complete this study.
- Trial name
- NCT03586648
- Testing
- senofilcon A Multifocal, senofilcon A Sphere, etafilcon A Multifocal
- Where
- 6 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Aphakia, Cataract
Comparison of the Hoya Surgical Optics (HSO) iSert 251 Posterior Chamber Aspheric Aphakic Intraocular Lens to Historical / Literature Controls.
The purpose of this multi-center clinical trail is to determine the safety and efficacy of the iSert 251 for the correction of aphakia.
- Trial name
- NCT01292629
- Testing
- iSert 251 intraocular lens
- Where
- 5 sites in United States
- Volunteers
- 125 people
- Sponsor
- Hoya Surgical Optics, Inc.
Visual Acuity
Clinical Investigation of Visual Acuity in Contact Lens Wearers After Instillation of a Lipid- Based Lubricating Eye Drop
This is a single visit, randomized, double masked, bilateral, non-dispensing, 2×2 crossover study to assess visual acuity.
- Trial name
- NCT06131476
- Testing
- Blink® Tears eye drops, Investigational lipid eye drops
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses
The study is a bilateral, single-masked, single-arm, 4-visit dispensing study. There will be one study treatment, with the subject being dispensed lenses for 6 to 8 days, then lens power will be optimized (if necessary) and…
- Trial name
- NCT04974697
- Testing
- JJVC Investigational Multifocal Toric Contact Lens
- Where
- 8 sites in United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of Manufacturing Processes for a Reusable Multifocal Optical Design in a Presbyopic Population
The clinical study is a randomized-controlled, double-masked, crossover clinical trial with two study treatments to compare two study lens types and the initial performance, in terms of the subjective response after a period of…
- Trial name
- NCT03787472
- Testing
- JJV Investigational senofilcon A Multifocal Lens1, JJV Investigational senofilcon A Multifocal Lens2
- Where
- 5 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.