Clinical trials: Visual Acuity
Visual Acuity
Characterizing Successful Myopic Multifocal Contact Lens Wearers
This will be a prospective, single group, single-arm, and bilateral dispensing study. Subjects will be assigned to a single study lens type to be worn bilaterally in daily wear, and daily disposable modality, for at least 6 hours…
- Trial name
- NCT04178772
- Testing
- Acuvue Moist Multifocal Contact Lens JJVC Marketed Contact Lens
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Effects of Multifocal Contact Lens on Ocular Tissue
The purpose of this study is to evaluate the etafilcon - PVP (multi-focal)
- Trial name
- NCT02345720
- Testing
- etafilcon - PVP (multi-focal)
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Age - Related Macular Degeneration (AMD)
Study to Assess Best Corrected Visual Acuity (BCVA) in Patients With Neovascular Age-Related Macular Degeneration (AMD) Who Are Administered VEGF Trap-Eye (Intravitreal Aflibercept Injection)
This is a phase 4, open-label, single arm, multicenter, clinical study in patients with neovascular AMD designed to evaluate the efficacy and safety of Intravitreal Aflibercept Injection (IAI) administered over 2 years , and to…
- Trial name
- RE-VIEW (NCT01722045)
- Testing
- Intravitreal Aflibercept Injection (IAI)
- Where
- 49 sites in United States
- Volunteers
- 154 people
- Sponsor
- Regeneron Pharmaceuticals
Visual Acuity
Evaluation of Rotation With a Multifocal Toric Contact Lens
The study is a bilateral, single-masked, single-visit, non-dispensing 2x2 crossover study to confirm a finalized design of a prototype contact lens.
- Trial name
- NCT05433571
- Testing
- Test Lens
- Where
- 5 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Neovascular Age-related Macular Degeneration
Open-label Extension Study of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) in Neovascular ("Wet") Age-related Macular Degeneration (AMD)
The primary objective is to assess long-term safety and tolerability of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) in patients with neovascular AMD.
- Trial name
- NCT00964795
- Testing
- Intravitreal Aflibercept Injection 2mg
- Where
- 124 sites in United States, Canada
- Volunteers
- 323 people
- Sponsor
- Regeneron Pharmaceuticals
Visual Acuity
An Investigation of the Impact of Localized Topical Anesthesia of the Ocular Surface on End-of-day Contact Lens Discomfort
This is a controlled, randomized, subject-masked, 3x3 crossover, non-dispensing, contralateral study. Twenty subjects will be recruited based on their scores (with their habitual lenses) from the Contact Lens Dry Eye…
- Trial name
- NCT03733899
- Testing
- Local Anesthesia
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of Multifocal Contact Lens Designs With and Without an HEV Blocker on Visual Function
This is a single-masked, bilateral, controlled, randomized, 2x2 crossover, non-dispensing clinical trial to characterize the effects of an HEV-Blocker on several measures of visual function in a presbyopic population.
- Trial name
- NCT04995055
- Testing
- JJVC Investigational Multifocal Contact Lens TEST Lens, ACUVUE® OASYS Multifocal
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population; Part 2
This is a 6-visit, subject-masked, multi-site, 2×3 crossover dispensing trial that will last approximately 2 - 4 months.
- Trial name
- NCT04615507
- Testing
- JJVC Investigational Multifocal Contact Lens, Dailies Total 1® Multifocal Contact Lens
- Where
- 6 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of Daily Disposable Etafilcon A Cosmetic Contact Lenses
This will be a randomized, double-masked, bilateral, cross-over, 2 treatment by 2 period dispensing study. There will be 4 visits. There will be a 2 to 5 day washout period between treatments.
- Trial name
- NCT04529109
- Testing
- etafilcon A investigational cosmetic lens 1, etafilcon A investigational cosmetic lens 2
- Where
- 4 sites in United States, Hong Kong
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Influence of Lens Design on Particulate Exchange in the Post-lens Tear Film
This is a 5-visit, controlled, bilateral, randomized, subject-masked, crossover (4 treatments x 4 period), non-dispensing study.
- Trial name
- NCT03782571
- Testing
- etafilcon a Test 1, etafilcon A Test 2, etafilcon A Test 3
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Choroidal Neovascularization Secondary to Pathologic Myopia
A Study of the Criteria Establishing the Need for Re-treatment With Ranibizumab Upon Relapse in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia.
The primary objective of the study was to investigate current criteria driving re-treatment in patients affected by Choroidal Neovascularization (CNV) secondary to Pathologic Myopia (PM) and experiencing a relapse of the disease…
- Trial name
- OLIMPIC (NCT02034006)
- Testing
- Ranibizumab
- Where
- 31 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Novartis Pharmaceuticals
Corneal Ulcer, Eye Infections, Bacterial
Steroids for Corneal Ulcers Trial
The purpose of this study is to determine whether adding topical steroids improves the outcomes of bacterial corneal ulcers, especially visual acuity.
- Trial name
- SCUT (NCT00324168)
- Testing
- Antibiotics, Topical corticosteroid
- Where
- 5 sites in United States, India
- Volunteers
- 500 people
- Sponsor
- Thomas M. Lietman
Visual Acuity
Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population
This is a single-masked, crossover, randomized-controlled, dispensing clinical trial. A total of approximately 70 myopic eligible subjects will be targeted to complete the study.
- Trial name
- NCT04310566
- Testing
- JJVC Investigational Multifocal Contact Lens (senofilcon A c3), Dailies Total 1® Multifocal Contact Lens
- Where
- 7 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses
The study is a bilateral, single-masked, single-arm, 4-visit dispensing study. There will be one study treatment, with the subject being dispensed lenses for 6 to 8 days, then lens power will be optimized (if necessary) and…
- Trial name
- NCT04974697
- Testing
- JJVC Investigational Multifocal Toric Contact Lens
- Where
- 8 sites in United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
The Effects of Contact Lenses With UV/HEV-Filter on Visual Function
This is a 2-phase, single-site, non-dispensing, randomized, controlled, double-masked, 2x2 crossover study to objectively measure potential benefits of a new UV/HEV filter using psychophysical testing techniques.
- Trial name
- NCT05601544
- Testing
- ACUVUE OASYS 1-Day, ACUVUE OASYS MAX 1-Day, ACUVUE OASYS Multifocal
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Diabetic Macular Edema
Treatment for CI-DME in Eyes With Very Good VA Study
Although multiple studies have clearly demonstrated that ranibizumab therapy is more effective than laser alone for vision gain and avoiding vision loss in patients with central-involved Diabetic Macular Edema (DME), only eyes…
- Trial name
- Protocol V (NCT01909791)
- Testing
- Prompt Laser, Prompt aflibercept, Deferred laser
- Where
- 103 sites in United States, Canada
- Volunteers
- 702 people
- Sponsor
- Jaeb Center for Health Research
Visual Acuity
Clinical Performance Evaluation of Two Silicone Hydrogel Lenses
This is a randomized, double-masked dispensing study where subjects will randomized into one of two lens sequences to wear each of two contact lens types for a 4-week period with each lens type.
- Trial name
- NCT02756078
- Testing
- TEST Contact Lens, CONTROL Contact Lens
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Vision
Safety Study Looking at the Effects of Stendra on Vision
The purpose of this study is to see if Stendra causes any changes in vision, eye pressure, pupil dilation, and color vision in healthy males.
- Trial name
- NCT02033200
- Testing
- Stendra 200 mg
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Visual Acuity
Design Validation of Senofilcon A With New UV-blocking Additive
This is a 2-visit, multi-site, partially subject-masked, 2-arm parallel, controlled, randomized and dispensing trial. Subjects will be randomized to one of two study lenses for the entire duration of the study.
- Trial name
- NCT03707821
- Testing
- senofilcon A TEST Lens, senofilcon A CONTROL Lens
- Where
- 10 sites in United States
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Symptomatic Vitreomacular Adhesion
A Phase III Study of A01016 in Subjects With Symptomatic Vitreomacular Adhesion
The purpose of this study is to evaluate the superiority regarding vitreomacular adhesion (VMA) resolution of a single intravitreal injection of A01016 (Ocriplasmin) compared to sham-injection in subjects with symptomatic VMA.
- Trial name
- NCT01889251
- Testing
- Ocriplasmin
- Where
- Japan
- Volunteers
- 251 people
- Sponsor
- Alcon Research