Clinical trials: Visual Acuity
Visual Acuity
Clinical Comparison of Two Marketed Reusable Cosmetic Contact Lenses
This will be a 4-visit, multi-site, randomized, brand-masked, bilateral, 2×2 crossover study. If a subject is found to meet all eligibility criteria, they will be randomized to one of two lens wear sequences.
- Trial name
- NCT03755882
- Testing
- ACUVUE® DEFINE™ Vivid Style, LACELLE™ Sparkling Brown
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Retinopathy of Prematurity
Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2)
Retinopathy of prematurity (ROP) is a disorder of development of the neural retina and its vasculature that can impact vision in vulnerable preterm neonates for a lifetime.
- Trial name
- BabySTEPS2 (NCT04995341)
- Testing
- Investigational ultracompact OCT and OCTA system, retinal photographs
- Where
- 2 sites in United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Duke University
Visual Acuity
Clinical Evaluation of Approved Contact Lenses
This is a 4-week, randomized, double-masked study where subjects will wear bilaterally test and control lenses in random succession. The objective is to evaluate materials from different suppliers.
- Trial name
- NCT02699593
- Testing
- Test Contact Lens, Control Contact Lens
- Where
- 7 sites in United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ametropia, Myopia; Refractive Error
The Objective of This Study is to Evaluate the Perfomance of a Photorefraction Device for Screening Ametropia in Children. Eligible Participants Will Undergo Multiple Refractive Error Measurements, Visual Acuity and Strabismus Assessments During a Single Evaluation Visit.
The goal of this clinical trial is to evaluate the performance of a photorefraction screener in terms of sensibility, sensitivity and accuracy on children aged 3 to 8 y.o.
- Conditions
- Ametropia, Myopia; Refractive Error, Myopia; Astigmatism
- Trial name
- NCT06882408
- Testing
- Photorefraction device under investigation, Comparator device, Tabletop auto-refractometer, Comparator device, portable photorefraction device
- Where
- 2 sites in France
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Essilor International
Visual Acuity
Clinical Evaluation of Fitting Investigational Contact Lenses
This study is a non-randomized, open label, bilateral, non- dispensing clinical trial with only one visit. The Eye Care Providers will be provided with a fitting guide and will determine the initial study lens selection.
- Trial name
- NCT03150485
- Testing
- JJVC Fitting Guides
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Impairment
Post-market Evaluation of OdySight App to Monitor Near Visual Acuity at Home (TIL002)
OdySight is a mobile application allowing self-testing of visual parameters including near visual acuity and communication of the data to an online dashboard to patient's doctors.
- Trial name
- TIL002 (NCT05510479)
- Testing
- Software as medical device
- Where
- 3 sites in France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Tilak Healthcare
Sensory Deficits
Falls Prevention: Gait-Synchronized Vibration System
The purpose of this study is to develop an abnormal gait detection algorithm and a vibratory stimulation system on a lower limb to improve gait stability and prevent falls.
- Trial name
- NCT02635113
- Testing
- Gait Synchronized Vibration System
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Cataracts
Comparing Optical Coherence Tomography (OCT) and Visual Acuity Outcomes in Subjects Undergoing Cataract Surgery, Who Receive Xibrom Ophthalmic Solution and Standard Presurgical Care vs. Xibrom Ophthalmic Solution Plus Prednisolone Acetate 1% and Standard Presurgical Care
To compare the efficacy of twice-daily topical bromfenac (Xibrom) ophthalmic solution alone versus twice-daily topical Xibrom with prednisolone acetate 1% three-times daily on visual acuity and OCT measurements.
- Trial name
- NCT00698724
- Testing
- Xibrom, and Optive, Xibrom and Pred Forte
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bp Consulting, Inc
Visual Acuity Reduced Transiently
Changes in Power and Cylinder Axis of Toric Soft Contact Lenses (LKL)
Astigmatism is a common refractive error resulting from a toric-surfaced cornea which using a toric soft contact lens could be one of the therapy options.
- Trial name
- NCT04724525
- Testing
- soft contact lens Toric
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Visual Acuity
Clinical Evaluation of Two Marketed Artificial Tears in Non-contact Lens Wearing Patients
This clinical study is a randomized, double-masked, cross-over, bilateral, 2 treatment x 2 period, dispensing 4-visit study with a 7-9 day washout period in between visits 2 and 3. The study will last approximately 3 months.
- Trial name
- NCT03466086
- Testing
- Test Eye Drops, Control Eye Drops
- Where
- United Kingdom
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of Approved and Investigational Contact Lenses Using New UV Additive
Randomized, 8-visit dispensing study over 14 weeks to evaluate the safety and efficacy of an investigational contact lens with a new UV blocker compared to a marketed contact lens.
- Trial name
- NCT02982018
- Testing
- senofilcon A with new UV blocker, senofilcon A
- Where
- 6 sites in United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Validation of Senofilcon A With New UV / HEV Filter
This is a bilateral, dispensing, randomized, controlled, subject-masked, 2-arm parallel study to evaluate safety and efficacy
- Trial name
- NCT05099380
- Testing
- senofilcon A C3, senofilcon A
- Where
- 17 sites in United States
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Macular Degeneration, Geographic Atrophy
A Prospective Observational Study to Assess the Reliability and Validity of the MLSDT
The goal of this observational study is to assess the reliability and validity of the 9-object MLSDT for evaluation of participants with moderate to severe vision impairment when tested without a wearable low-vision magnifying…
- Conditions
- Macular Degeneration, Geographic Atrophy, Stargardt Disease
- Trial name
- NCT06805474
- Testing
- Observational
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nanoscope Therapeutics Inc.
Visual Acuity
Evaluating ACUVUE® Abiliti™ 1-Day Soft Therapeutic Lenses for Myopia Management
This is a single-site, prospective, single-arm, open-label, real-world evidence study with a minimal study duration of 1-year, up to 2-year follow-up to evaluate overall visual acuity.
- Trial name
- NCT05634408
- Testing
- ACUVUE® Abiliti™ 1-Day Soft Therapeutic Lenses for Myopia Management (A1D)
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ophthalmopathy
Assessing Agreement Between Acuvera Capture and Paper-Based Methods for BCVA Data Recording in Ophthalmic Trials
Study Purpose: To evaluate the level of agreement between the Acuvera Capture application and traditional paper-based methods for recording Best Corrected Visual Acuity (BCVA) in ophthalmic clinical trials.
- Trial name
- VALiCAPTURE (NCT07613580)
- Where
- 2 sites in Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- OptymEdge, LLC
Diabetic Macular Edema, Hard Lipid Exudates
The Effect of Intravitreal Ranibizumab on Visual Acuity and Hard Exudate Resolution in the Treatment of Diabetic Macular Edema With Center Involved Edema and Lipid Exudates
This is an open-label, Phase I/II study of intravitreally administered 0.3mg ranibizumab in subjects with diabetic macular edema and lipid exudates in the central subfield.
- Trial name
- NCT02448446
- Testing
- ranibizumab 0.3mg
- Where
- 4 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- South Coast Retina Center; Carson, McBeath, Boswell, Inc.
Visual Acuity
Evaluation of A Marketed Silicone Hydrogel Spherical Lens Used for Monovision Correction of Presbyopia
This is a single-masked, dispensing clinical trial. A total of approximately 48 myopic and 32 hyperopic eligible subjects will be targeted to complete the study.
- Trial name
- NCT04073186
- Testing
- ACUVUE® OASYS with Transitions™
- Where
- 5 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Healthy
Fluorophotometry Evaluation of Lubricant Eye Drops
The objective of this study is to evaluate the safety and efficacy of exaggerated use of Lubricant Eye Drops in a population of normal subjects by measuring corneal epithelial permeability to fluorescein.
- Trial name
- NCT00347854
- Testing
- Systane Free lubricant eye drops, Visine Tears Lubricant Eye Drops, Refresh Liquigel Lubricant Eye Drops
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Age Related Macular Degeneration
Optimising Visual Acuity Measurement in Macular Degeneration
Age-related macular degeneration (AMD) is the leading cause of visual impairment in the UK. The condition is characterised by damage to the region of the retina (macula) responsible for detailed central vision, this leading to…
- Trial name
- OPTIMISE (NCT04920071)
- Testing
- Visual acuity and contrast sensitivity measurement
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Visual Acuity
An Investigation of the Impact of Localized Topical Anesthesia of the Ocular Surface on End-of-day Contact Lens Discomfort
This is a controlled, randomized, subject-masked, 3x3 crossover, non-dispensing, contralateral study. Twenty subjects will be recruited based on their scores (with their habitual lenses) from the Contact Lens Dry Eye…
- Trial name
- NCT03733899
- Testing
- Local Anesthesia
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.