Clinical trials: Vision Impairment
Age Related Macular Degeneration
Study of WA-NG Telescope Prosthesis in Patients With End-stage Age-related Macular Degeneration
This is a pilot study to evaluate the safety of the Model WA-NG telescope prosthesis in patients with bilateral moderate to profound central vision impairment due to end-stage age-related macular degeneration.
- Trial name
- NCT01731964
- Testing
- Telescope prosthesis, WA-NG Telescope Prothesis
- Where
- Israel
- Sponsor
- VisionCare, Inc.
Macular Edema, Retinal Vein Occlusion
A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Patients With Macular Edema Due to Retinal Vein Occlusion (RVO)
This Phase 3 study will evaluate the efficacy, durability, and safety of KSI-301 compared to aflibercept, in participants with macular edema due to treatment-naïve branch (BRVO) or central retinal vein occlusion (CRVO).
- Trial name
- BEACON (NCT04592419)
- Testing
- KSI-301, Aflibercept
- Where
- 141 sites in United States, Czechia and 10 more
- Volunteers
- 568 people
- Sponsor
- Kodiak Sciences Inc
Vision Loss Partial, Vision; Loss, Both Eyes
Effect of Visual Retraining After Stroke
This project is intended to collect data using standard clinical tests and psychophysics to quantify the effect of visual cortical damage on the structure of the residual visual system, visual perception, spatial awareness, and…
- Conditions
- Vision Loss Partial, Vision; Loss, Both Eyes, Hemianopia Homonymous, Hemianopia
- Trial name
- urochester (NCT06121219)
- Testing
- Training in the Blind Field
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Intellectual Disability, Intellectual Impairment
Perceptual-vision Training and Intellectual Disabilities
Physical activity for healthy ageing is an important feature and the possibility to detect practical solutions to solve the need for feasible health promotion interventions to reduce health disparities and wellbeing in…
- Conditions
- Intellectual Disability, Intellectual Impairment, Activity, Motor, Sports Physical Therapy
- Trial name
- NCT06628999
- Testing
- Visual Training, Control Group, Visual Training-detraining
- Volunteers
- healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Amblyopia, Anisometropia
Amblyopia (Lazy Eye) Treatment Study
The purpose of this study is to compare the results of two standard treatments for amblyopia in order to find out if one is more effective than the other.
- Conditions
- Amblyopia, Anisometropia, Strabismus
- Trial name
- NCT00001864
- Testing
- Atropine, Patch
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Eye Institute (NEI)
Visual Impairment, Cerebral Visual Impairment
VIPPSTAR-G1 Digital Early Intervention for Visual Impairment
Visual impairment in infancy is associated with significant risks for neurodevelopmental impairment. Early intervention based on enriched visual and multisensory experiences may promote neuroplasticity and improve developmental…
- Conditions
- Visual Impairment, Cerebral Visual Impairment, Neurodevelopmental Disorders, Prematurity
- Trial name
- VIPPSTAR-G1 (NCT07717671)
- Testing
- VIPPSTAR Digital Early Intervention, Standard Clinical Care
- Where
- 5 sites in Belgium, Italy and 1 more
- Volunteers
- 150 people
- Sponsor
- Università degli Studi di Brescia
Central Retinal Vein Occlusion
Ranibizumab Intravitreal Injections Versus Sham Control in Patients With Central Retinal Vein Occlusion (CRVO)
Provide efficacy and safety data on intravitreal injections of ranibizumab 0.5 mg in patients with visual impairment due to macular edema secondary to CRVO
- Trial name
- Camellia (NCT01976312)
- Testing
- Ranibizumab 0.5 mg
- Where
- 34 sites in China, Hong Kong and 5 more
- Volunteers
- 252 people
- Sponsor
- Novartis Pharmaceuticals
Visual Impairment
Development and Validation of an Automated Self-administered Visual Acuity System
Visual acuity tests, commonly conducted in clinics and used for health screenings, are becoming more in demand due to an aging population.
- Trial name
- AutoVA (NCT06540001)
- Testing
- Automated visual acuity
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Age-Related Macular Degeneration, Geographic Atrophy
A Study of the SING IMT in an Israeli Cohort
The objective of this single center study is to determine the safety of the smaller incision, new generation (SING), implantable miniature telescope (IMT) in a small sample of patients with moderate-severe central vision loss due…
- Trial name
- NCT05941273
- Testing
- smaller incision, new generation implantable miniature telescope (SING-IMT)
- Sponsor
- VisionCare, Inc.
Blindness, Acquired, Blindness Congenital
Effects of Transcranial Direct Current Stimulation With Proprioceptive Training in Blind People
Postural control requires the integration of the vestibular, visual, and somatosensory systems. Vision, in particular, exerts a considerable influence on body sway during activities that require balance.
- Trial name
- NCT03173105
- Testing
- active tDCS, Dynamic proprioceptive exercises, static proprioceptive exercises
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Salgado Institute of Integral Health
Vision Loss Partial, Hemianopia
Effect of Visual Retraining on Visual Loss Following Visual Cortical Damage
This project is intended to collect data using standard clinical tests and psychophysics to quantify the effect of visual cortical damage on the structure of the residual visual system, visual perception, spatial awareness, and…
- Conditions
- Vision Loss Partial, Hemianopia, Hemianopia Homonymous, Quadrantanopia
- Trial name
- NCT05098236
- Testing
- Training in the Blind Field, Training in the Sighted Field
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Low Vision, Central Visual Impairment
Vision Rehabilitation Training With Multimodal Feedback in Central Vision Loss
Central vision loss from macular degeneration creates blind spots that impair reading, face recognition, and navigation. Individuals must learn to use peripheral vision, requiring retraining of eye movements.
- Conditions
- Low Vision, Central Visual Impairment, Macular Degeneration
- Trial name
- NCT07577219
- Testing
- eccentric viewing training with biofeedback
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- New England College of Optometry
Vision Impairment
Providing Access to the Visual Environment
Providing Access to the Visual Environment is a pediatric low vision grant which has the ability to provide comprehensive, interdisciplinary low vision rehabilitation services to every child in Tennessee with a vision impairment.
- Trial name
- NCT00341744
- Where
- United States
- Volunteers
- 795 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Hearing Loss, Hearing Loss, Age-Related
Sight and Hearing Investigation Into Effects on Delirium
The goal of this observational study is to learn about sensory loss in hospital patients with delirium. The main questions it aims to answer are: Are hearing and vision loss related to increased risk of having delirium? Do…
- Conditions
- Hearing Loss, Hearing Loss, Age-Related, Hearing Disability, Delirium
- Trial name
- SHIELD (NCT06176625)
- Testing
- Communication Signage, Amplifier Use
- Where
- United States
- Volunteers
- 1,543 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Low Vision
Design and Clinical Evaluation of a Smartphone-based Low Vision Enhancement System
The primary objective is to compare the effectiveness and adverse side-effects of the virtual bioptic telescope and virtual projection screen in a new head-mounted video-based low vision enhancement system (LVES) with a wide…
- Trial name
- eLVES (NCT03728660)
- Testing
- Virtual bioptic magnification with large field of view, Full field magnification with small field of view
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Johns Hopkins University
Visual Impairment, Healthy
Touching the World With a Cane: Cognitive and Neural Processes
The use of tools is ubiquitous in our lives and allows us to expand the sensorimotor capacities of our body. Much research has been done on the subject in sighted people over the past decades.
- Trial name
- TOOL_TOUCH (NCT05199896)
- Testing
- Behavioral protocol, EEG protocol, fMRI protocol
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Vision Impairment
Restricted Useful Field View as a Risk Factor in Older Adults
The relationship between Useful Field of Vision (UFOV) and falls taken by the elderly will be investigated. UFOV is a test which measures visual attention.
- Trial name
- NCT00013351
- Testing
- Prevention of Falls
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- US Department of Veterans Affairs
Photophobia, Visual Impairment
Improving Glare and Visual Comfort for Patients With Visual Impairment
To assess the use of contact lenses with transitions technology to improve glare, light sensitivity and overall visual comfort in patients with visual impairment.
- Conditions
- Photophobia, Visual Impairment, Low Vision
- Trial name
- NCT05829135
- Testing
- Acuvue Oasys with Transitions
- Where
- United States
- Sponsor
- Nova Southeastern University
Uveomeningoencephalitic Syndrome, Inflammation
Multimodal Analysis and Electroretinogram in VKH From Acute Onset - Part I
Patients with acute onset Vogt-Koyanagi-Harada disease (VKHD) were prospectively included in this study. They were systematically followed with clinical, posterior segment imaging exams and full-field electroretinogram during a…
- Conditions
- Uveomeningoencephalitic Syndrome, Inflammation, Choroid Disease, Visual Impairment
- Trial name
- NCT03811366
- Testing
- Corticosteroid monotherapy
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- University of Sao Paulo
Trauma, Infections
Ophthalmological Emergencies and COVID-19 Pandemia
To analyze how the COVID 19 pandemia has affected the patient's accesses to the Ophthalmological Emergency Department of a tertiary referral center in northern Italy, during the lockdown period.
- Conditions
- Trauma, Infections, Vision; Loss, Both Eyes
- Trial name
- NCT05065788
- Testing
- data collection
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Università degli Studi dell'Insubria