Clinical trials: Vision Disorders
Stroke, Blindness
Functional Neuroimaging of Cortical Plasticity in the Human Visual System
The study's objective is to measure changes in human visual cortex organization that may arise as a result of injury to the visual pathways.
- Conditions
- Stroke, Blindness, Vision
- Trial name
- NCT01062672
- Where
- 2 sites in United States, Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Uveitis
UNICORNS: Uveitis in Childhood Prospective National Cohort Study
Childhood uveitis (inflammation inside the eye) is an uncommon disorder that carries the risk of blindness. Inadequate treatment of active inflammation has been shown to be related to a poor outcome.
- Trial name
- UNICORNS (NCT05385757)
- Where
- 31 sites in United Kingdom
- Volunteers
- 250 people
- Sponsor
- Institute of Child Health
GLAUCOMA 1, OPEN ANGLE, D (Disorder)
Preserflo MicroShunt Versus Trabeculectomy
The goal of this randomized controlled clinical trial is to learn whether two minimally invasive bleb-forming glaucoma implants can effectively treat adult patients with open-angle glaucoma who require surgical lowering of…
- Trial name
- PMSvT (NCT07496957)
- Testing
- Preserflo MicroShunt Implantation, Trabeculectomy with MMC
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Bialystok
CLN3-related Disorders, Non-CLN3 Related Low Vision
Optic-to-Audio Device in a Pediatric Cohort With CLN3-related Conditions or Low Vision
Background: CLN3 involves vision loss observed around the preschool years, with eventual progression to blindness within 1-3 years.
- Trial name
- NCT04974307
- Testing
- OrCam MyEye 2
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Glaucoma
Bevacizumab Versus Mitomycin C as Trabeculectomy Adjuvant in Uncontrolled Glaucoma
Refractory glaucoma often requires vision-sparing trabeculectomy. To increase surgical success, adjunctive pharmacotherapy is utilized albeit the risk of adverse events.
- Trial name
- AvastinvsMMC (NCT02901236)
- Testing
- Standard Guarded Trabeculectomy, Mitomycin C, Bevacizumab
- Volunteers
- 40 people
- Sponsor
- Athens Vision Eye Institute
Uveitis
Intestinal Bacteria and Ocular Inflammatory Disease
Background: Uveitis is a general term describing a group of inflammatory diseases of the eye. The causes of uveitis are not fully understood.
- Trial name
- NCT01859299
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- National Eye Institute (NEI)
Cataracts, Corneal Edema
Study of Difluprednate vs. Prednisolone Acetate on Visual Acuity, and Corneal Edema Following Cataract Surgery.
The purpose of this clinical research study is to investigate the efficacy of predosing patients undergoing cataract surgery with the potent corticosteroid difluprednate ophthalmic emulsion 0.05% compared to prednisolone acetate…
- Conditions
- Cataracts, Corneal Edema, Retinal Structural Change, Deposit and Degeneration, Visual Acuity Reduced Transiently
- Trial name
- NCT01244334
- Testing
- Difluprednate ophthalmic emulsion 0.05%, Prednisolone acetate 1%
- Where
- 3 sites in United States
- Volunteers
- 52 people
- Sponsor
- Edward J. Holland
Cataract
Comfort Operative Ocular Light Study
Digital 3D microscopes require less light and may be more comfortable for patients requiring cataract surgery under topical anesthesia compared to conventional microscopes.
- Trial name
- COOL (NCT05085314)
- Testing
- Ngenuity digital 3D microscope, Conventional microscope
- Where
- 2 sites in France
- Volunteers
- 134 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Children With Torticollis
Tilted Gaze Target Test in the Examination of Children With Superior Oblique Muscle Palsy
This study is a prospective, randomized, double-blind cohort study aimed at assessing the accuracy of the preoperative tilted gaze target test in predicting the degree of improvement in compensatory head position after surgery in…
- Trial name
- NCT05882552
- Testing
- Tilted Gaze Target Tast, Conventional Examination Methods
- Volunteers
- 80 people
- Sponsor
- Tianjin Eye Hospital
Cataract
Evaluation of Quality of Vision and Spectacle Independence With the AcrySof® Panoptix® Intraocular Lens
This is a study to assess the spectacle independence and quality of vision of patients receiving the AcrySof® Panoptix® Intraocular lens (IOL) after uneventful cataract surgery.
- Trial name
- NCT04124952
- Testing
- Panoptix
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SightTrust Eye Institute
Diabetic Retinopathy
Single In-Clinic Encounter With the Notal Vision Home OCT by DME Patients
In this clinical study the Notal Vision Home OCT (NVHO) Monitoring System will be used to evaluate the ability of patients diagnosed with DME to perform sequential self-images of their eyes with the self-operated NVHO device in a…
- Trial name
- NCT05417152
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- Notal Vision Inc.
Myopia
To Study the Effects of Cordyceps Cicadae on Vision Care
Cordyceps cicadae is a traditional Asian herbal medicine with a variety of bioactive substances and curative effects similar to Cordyceps Cicadae, and it has been reported that anti-dry eye and eye protection ingredients can be…
- Trial name
- NCT05778409
- Testing
- Cordyceps cicadae extract
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Glaucoma
Clinical Effectiveness of Low Vision Rehabilitation in Glaucoma Patients
Our team is interested in what can be done to improve the functioning of patients who suffer from glaucoma, a chronic and irreversible eye disease.
- Trial name
- LOVIT (NCT01262209)
- Testing
- portable CCTV, Telescopes, telemicroscopes and microscopes, Absorptive filters
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Dry Eye Syndrome
Efficacy and Safety of the Ophthalmic Solution PRO-087 Versus Systane ® Ultra and Ultra Preservative Free (087LATAMFIV)
Efficacy and Safety of the Ophthalmic Solution PRO-087 versus Systane ® Ultra and Systane ® Ultra Preservative Free on the Tear Film Dysfunction Syndrome from Mild to Moderate Clinical trial To evaluate the effectiveness of…
- Trial name
- 087LATAMFIV (NCT03223909)
- Testing
- PRO-087, Systane Ultra, Systane Ultra Preservative Free
- Where
- Mexico
- Volunteers
- 326 people
- Sponsor
- Laboratorios Sophia S.A de C.V.
Obtaining OCT (Optical Coherence Tomography) Images
Self-Monitoring OCT
The purpose of this research study is to test participants ability to obtain OCT images of the eyes using an OCT device that is comparable to FDA-approved OCT devices on the market, without the help of an eye technician.
- Trial name
- NCT07584798
- Testing
- Self-administered OCT imaging system, Technician-acquired OCT imaging
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Vision Impairment, Eye Diseases
The Proactive Ophthalmic Examination Cohort
The Proactive Ophthalmic Examination Cohort of Older Adults is a prospective cohort study recruiting community-dwelling older adults aged 65 years or older.
- Trial name
- POEC (NCT05851287)
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Evaluation of Short Term Use of Experimental Eye Drops BHVI2, 0.02% Atropine and BHVI2 Plus 0.02% Atropine Eye Drops
To assess the one-month ocular effects of nightly application of experimental BHVI2 and 0.02% atropine eye drops either alone or in combination, in children aged between 6 to 13 years old with myopia and randomized to use of…
- Trial name
- NCT03690414
- Testing
- Experimental BHVI2, Atropine sulfate 0.02% eye drops, Combination eye drops
- Where
- Vietnam
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hai Yen Eye Care
Healthy, Teenagers
Effect of an Audio Instructional Program Regarding Puberty on Self-Concept and Healthy Behaviors of Teenage Girls With Visual Impairment
Background: Teenage girls, who are a vulnerable group, require special care and attention, particularly when puberty begins. A consistent teaching program about menstruation should be offered to adolescent girls with visual…
- Conditions
- Healthy, Teenagers, Girls, Self-concept
- Trial name
- Teen Audio (NCT07496606)
- Testing
- structured audio instructional program regarding puberty
- Where
- Palestinian Territories
- Volunteers
- 46 people
- Sponsor
- Al-Quds University
Glaucoma
This Study Examines Whether Personality Traits Influence the Frequency or Severity of Ocular Adverse Effects Reported by Patients Using Glaucoma Medications. The Findings May Identify Patients at Greater Risk of Intolerance and Support More Personalized Treatment and Counselling.
The goal of this observational study is to learn whether personality traits are related to eye side effects from glaucoma medications in adults who currently use or previously used these medications.
- Trial name
- Adverse Events (NCT07739784)
- Testing
- No Interventions
- Where
- Canada
- Volunteers
- 352 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Amblyopia, Refractive Errors
Vision Screening for the Detection of Amblyopia
INTRODUCTION. Amblyopia is defined as the loss of visual acuity (VA) in one or both eyes, without any obvious structural or pathological anomalies.
- Conditions
- Amblyopia, Refractive Errors, Anisometropia, Strabismus
- Trial name
- NCT01430247
- Testing
- Amblyopia screening
- Where
- Croatia
- Volunteers
- 7,000 people
- Sponsor
- Mladen Busic