Clinical trials: Vision Disorder
Hemianopia, Brain Injuries
Biofeedback Training for Hemianopia
This is a prospective study that compares biofeedback training on the microperimetry (BT) to a control group in patient s with hemianopia.
- Trial name
- NCT06995313
- Testing
- Biofeedback training
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University Health Network, Toronto
Synkinesis, Facial Nerve Palsy
Efficacy of Topical Apraclonidine for the Treatment of Ocular Synkinesis
The purpose of this study is to determine efficacy of apraclonidine for patients with ocular synkinesis, who are seen in the UAB Facial Nerve Clinic.
- Trial name
- NCT05167760
- Testing
- Apraclonidine
- Sponsor
- University of Alabama at Birmingham
Glaucoma, Open-Angle
Micropulsed Laser Trabeculoplasty Using Different Parameters
This randomized, double blinded, clinical trial compares two different parameters setting of micropulsed laser trabeculoplasty for open angle glaucoma. Group one is treated with 1500 mW of Power, Group two with 1000 mW.
- Trial name
- NCT04900142
- Testing
- Micropulsed laser trabeculoplasty
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Modena and Reggio Emilia
Primary Open Angle Glaucoma, Pseudoexfoliative Glaucoma
Comparing Effectiveness of the Hydrus Microstent (TM) to Two iStents to Lower IOP in Phakic Eyes
This clinical trial compares two implantable devices intended to lower the pressure inside the eye of glaucoma patients.
- Conditions
- Primary Open Angle Glaucoma, Pseudoexfoliative Glaucoma, Pigmentary Glaucoma
- Trial name
- COMPARE (NCT02023242)
- Testing
- Hydrus Microstent, iStent Trabecular Micro Bypass
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Ivantis, Inc.
Glaucoma
Outcomes of Intraoperative 5-Fluorouracil Versus Mitomycin C
A clinical trial to establish the long term response of using intraoperative 5-fluorouracil (5-FU) versus mitomycin C (MMC) in trabeculectomy glaucoma surgery.
- Trial name
- NCT00346489
- Testing
- 5-fluorouracil, Mitomycin C
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Indiana University
Abducens Nerve Paralysis
Effects of Ocular Electroacupuncture on Abducens Nerve Palsy
The purpose of the study is to testify the efficacy of treating abducens nerve palsy with ocular electroacupuncture or ocular acupuncture, and to compare the efficacy between these two interventions.
- Trial name
- NCT03099460
- Testing
- ocular electroacupuncture, ocular acupuncture
- Where
- China
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Ischemic Optic Neuropathy, Branch Retinal Artery Occlusion
New Non-invasive Modalities for Assessing Retinal Structure and Function
This study investigates a new technology to assess the structure and function inside the eye. Retinal imaging of subjects with inner and outer retinal defects to detect areas of abnormal structure and function compared to other…
- Conditions
- Ischemic Optic Neuropathy, Branch Retinal Artery Occlusion, Hemianopia, Leber Hereditary Optic Neuropathy
- Trial name
- NCT03475173
- Testing
- LSFG-NAVI
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Randy Kardon
Orbital Fractures, Blow Out Fracture of Orbit
Orbital Fractures Registry
Approximately 300 patients presenting orbital blow-out fracture will be enrolled prospectively in this registry. All patients, surgically and nonsurgically treated as per standard (routine) of care will be followed-up (FU) within…
- Trial name
- OFx (NCT03887988)
- Testing
- Primary "early" reconstruction, Nonsurgical, Primary "delayed" reconstruction
- Where
- 14 sites in United States, Germany and 10 more
- Volunteers
- 300 people
- Sponsor
- AO Innovation Translation Center
Proliferative Diabetic Retinopathy - High Risk
Ultra-Widefield Fluorescein Angiography-Based Targeted Retinal Photocoagulation Versus Conventional Panretinal Photocoagulation in the Preservation of Visual Function and Regression of Proliferative Diabetic Retinopathy
Proliferative diabetic retinopathy is a vision-threatening disease that can lead to irreversible visual loss. The treatment options for proliferative diabetic retinopathy are anti-VEGF injection and retinal photocoagulation.
- Trial name
- NCT06653361
- Testing
- Green laser
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Hayatabad Medical Complex
Parkinson Disease, Progressive Supranuclear Palsy
Early Biomarkers of Neurodegeneration in Parkinsonian Syndromes
Parkinson's disease (PD) is the most common degenerative Parkinson's syndrome and is linked, among other things, to the excessive accumulation of an abnormally aggregating protein, alpha-synuclein.
- Trial name
- SODIPARK (NCT06155942)
- Testing
- 7 Tesla MRI
- Where
- 6 sites in France
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Macular Holes, Epiretinal Membrane
Intraoperative OCT Guidance of Intraocular Surgery II
The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes.
- Conditions
- Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment
- Trial name
- MIOCT (NCT03713268)
- Testing
- Microscope integrated optical coherence tomography
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Duke University
Bradycardia, Strabismus
Oculocardiac Reflex Brain Wave Monitor
Oculocardiac reflex during routine strabismus surgery was prospectively observed in association with routine brain wave monitoring.
- Trial name
- OCRBIS (NCT03663413)
- Testing
- non-invasive monitor
- Volunteers
- 188 people
- Sponsor
- Alaska Blind Child Discovery
Subjects With Primary Open-angle Glaucoma (POAG)
Prospective Evaluation of Open-Angle Glaucoma Subjects on One Topical Hypotensive Medication Treated With Two iStents
The purpose of this study is to evaluate the intraocular pressure (IOP) lowering effect of two iStent devices in eyes of subjects with primary open-angle glaucoma
- Trial name
- NCT01252862
- Testing
- iStent
- Where
- Armenia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Glaukos Corporation
Diagnositic Efficacy of Deep Convolutional Neural Network in Differentiation of Glaucoma Visual Field From Non-glaucoma Visual Field
Diagnostic Efficacy of CNN in Differentiation of Visual Field
Glaucoma is currently the leading cause of irreversible blindness in the world. The multi-center study is designed to evaluate the efficacy of the convolutional neural network based algorithm in differentiation of glaucomatous…
- Trial name
- NCT03759483
- Testing
- AI diagnostic algorithm
- Where
- China
- Volunteers
- 437 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Amblyopia
Assessment of Device for Treatment of Amblyopia
The study will evaluate the effect of Reviview™, a dichoptic video display device for administrating a novel treatment protocol for Amblyopia (lazy eye) in kids.
- Trial name
- NCT02003235
- Testing
- Daily watching videos using Reviview™, a dichoptic video display device, for 60 min
- Where
- Israel
- Volunteers
- 35 people
- Sponsor
- Visior Technologies Ltd.
Lymphoma
Revlimid® Capsules Drug Use-results Surveillance (Relapsed or Refractory ATLL)
To understand the safety and efficacy of Revlimid® Capsules 2.5 mg and 5 mg (hereinafter referred to as Revlimid) under actual conditions of use in patients with relapsed or refractory adult T-cell leukemia lymphoma (hereinafter…
- Trial name
- NCT03098589
- Testing
- Revlimid
- Where
- Japan
- Volunteers
- 1,149 people
- Sponsor
- Celgene
Obstructive Sleep Apnea, Hypopnea Syndrome
Retinal Nerve Fiber Layer Thickness Measurements in Patients With Sleep Apnea Syndrome
The purpose of this study was to measure the retinal nerve fiber layer (RNFL) thickness in eyes of Obstructive Sleep Apnea/hypopnea syndrome (OSAHS) using optical coherence tomography (OCT), and assess whether it is decreased.
- Conditions
- Obstructive Sleep Apnea, Hypopnea Syndrome, Glaucoma
- Trial name
- NCT01188291
- Where
- Israel
- Volunteers
- 166 people
- Sponsor
- Carmel Medical Center
Myopia
Pilot Study of Neurovision to Improve Vision and Slow Myopia Progression in Children With Myopia
This is a pilot study to assess the effectiveness of Neurovision treatment in the improvement of vision in children being under-corrected and to assess the effectiveness of Neurovision treatment in slowing down myopia progression…
- Trial name
- NCT00348218
- Testing
- NeuroVision
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore National Eye Centre
Open Angle Glaucoma
MIMS® Retrospective Chart Review
This is a post-market clinical follow-up, retrospective chart review of MIMS® surgical procedures conducted during time period between Sep 2023 and April 2025.
- Trial name
- NCT06614218
- Testing
- Minimally Invasive Micro Sclerostomy
- Where
- Armenia
- Volunteers
- 34 people
- Sponsor
- Sanoculis Ltd
Open-Angle Glaucoma, Ocular Hypertension
A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular Hypertension
This study will evaluate the 24-hour intraocular pressure lowering effect and safety after a single administration of Bimatoprost SR in patients with Open-Angle Glaucoma or Ocular Hypertension
- Trial name
- NCT04285580
- Testing
- Bimatoprost SR, LUMIGAN
- Where
- 6 sites in United States
- Volunteers
- 37 people
- Sponsor
- AbbVie