Clinical trials: Vision
Cataract
Presbyopia-Correcting Intraocular Lenses (IOLs)
The purpose of this study is to prospectively evaluate postoperative visual and refractive parameters in a series of subjects bilaterally implanted with Presbyopia-Correcting Intraocular Lenses (IOLs).
- Trial name
- NCT00963560
- Testing
- ReSTOR +3, Crystalens HD, Crystalens AO
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Alcon Research
Parkinson Disease, Progressive Supranuclear Palsy
Speech Accessibility Project
The goal of the Speech Accessibility Project at the University of Illinois Beckman Institute (https://speechaccessibilityproject.beckman.illinois.edu) is to collect, annotate, and curate a shared database of speech samples from…
- Conditions
- Parkinson Disease, Progressive Supranuclear Palsy, Multiple System Atrophy, Dementia With Lewy Bodies
- Trial name
- SAP (NCT05889260)
- Where
- 2 sites in United States
- Volunteers
- 485 people
- Sponsor
- University of Illinois at Urbana-Champaign
Cataract
Prospective Clinical Study of Unilateral or Bilateral Implantation of Intraocular Lens in Cataract Patients
This is to evaluate the satisfaction of patient and postoperative functional vision of unilateral or bilateral Implantation of intraocular lens（IOLs） in cataract patients.
- Trial name
- NCT04265820
- Testing
- unilateral implantation of IOL, bilateral implantation of IOL
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Open Angle Glaucoma or Ocular Hypertension
DE-111 Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension
Safety and IOP (intraocular pressure) lowering effect of DE-111 ophthalmic solution will be evaluated in open-angle glaucoma or ocular hypertension patients, in an open-label, multicenter study.
- Trial name
- NCT01343082
- Testing
- DE-111 ophthalmic solution
- Where
- Japan
- Volunteers
- 148 people
- Sponsor
- Santen Pharmaceutical Co., Ltd.
Glaucoma
Trusopt and Cosopt; Ocular Perfusion Pressure and Blood Flow: New Long-term Prospective Data
To analyze Cosopt® in terms of its effects on ocular perfusion pressure and comprehensive ocular blood flow and in relation to visual field progression and optic nerve structural changes in an ongoing 3 year prospective study…
- Trial name
- NCT01145898
- Testing
- (Cosopt®, prostaglandin)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Indiana University
Reconstructive Flap Surgery, Fasciocutaneous Anterolateral Thigh Flap
Anterolateral Tigh (ALT) Flaps Oxygenation Monitoring by NIRS
The goal of this observational study is to conduct postoperative monitoring in patients who have undergone upper or lower limb reconstructive surgery with an anterolateral thigh flap, by employing the gold standard approach…
- Conditions
- Reconstructive Flap Surgery, Fasciocutaneous Anterolateral Thigh Flap, Postoperative Monitoring, Flap Ischemia
- Trial name
- NCT06744387
- Testing
- clinical assessments and tissue oxygenation monitoring by Near Infrared Spectroscopy
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
Hippel-Lindau Disease
EYE001 to Treat Retinal Tumors in Patients With Von Hippel-Lindau Syndrome
This study will test the ability of the experimental drug EYE001 to reduce retinal thickening and improve vision in patients with Von Hippel-Lindau syndrome (VHL).
- Trial name
- NCT00056199
- Testing
- EYE001
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Eye Institute (NEI)
Amblyopia, Visual Training
A Randomized Controlled Trial of Autostereoscopic 3D Vision Therapy for Amblyopia
The goal of this clinical trial is to learn if an autostereoscopic 3D amblyopia training system works to improve vision in children and adolescents with amblyopia.
- Conditions
- Amblyopia, Visual Training, Visual Functions, Visual Health
- Trial name
- NCT07709832
- Testing
- Autostereoscopic 3D Training, Conventional Patching
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Beijing Tongren Hospital
Primary Open Angle Glaucoma
The Effects of an Antioxidant Formulation on Ocular Blood Flow
The objective is to evaluate the effects of an antioxidant formula versus placebo on ocular blood flow in a randomized double-blind, crossover design.
- Trial name
- NCT01930487
- Testing
- dietary supplement with antioxidants
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- ScienceBased Health
Amblyopia
Eye-tracking Based Amblyopia Training
An Eye-Tracking-Based Binocular Amblyopia Technology Improves Both Visual Acuity and Binocularity Screening A child is considered for the study after undergoing a standard of care and study-specific eye examinations (by a study…
- Trial name
- NCT05078099
- Testing
- CureSight
- Where
- Israel
- Volunteers
- 23 people
- Sponsor
- NovaSight
Myopia
A Study to Evaluate a Modified Contact Lens
This study is being conducted to evaluate the product performance of SofLens daily disposable contact lenses packaged in an investigational Test solution versus SofLens daily disposable contact lenses packaged in the currently…
- Trial name
- NCT01391364
- Testing
- SofLens in investigational solution, SofLens in currently marketed solution
- Where
- United States
- Volunteers
- 438 people
- Sponsor
- Bausch & Lomb Incorporated
Healthy Eyes
Evaluation of the Signal to Noise Ratio at Various Retinal Layers
Compare the signal to noise ratio of each device at various retinal layers.
- Trial name
- NCT02982174
- Testing
- 3D OCT-1 Maestro, DRI OCT Triton
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.
Myopia, Progressive, Myopia
Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression
This is a monocenter, randomized, controlled, parallel-group, double-masked clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation at baseline compared to a…
- Trial name
- NCT05331378
- Testing
- Test myopia control lenses, Single vision lenses
- Where
- Singapore
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Essilor International
Age Related Macular Degeneration
Molecular Imaging Exploration of Ocular Angiogenic Activity and Evaluation of Its Interest in the Therapeutic Follow-up of Patients With AMD (Age-related Macular Degeneration)
The main objective of this pilot study is to evaluate the ability of 68Ga-NODAGA-RGD PET imaging to demonstrate, in patients with unilateral AMD, a molecular therapeutic response to intraocular antiangiogenic injections at the…
- Trial name
- DMLA-RGD (NCT04005443)
- Testing
- radiopharmaceutical
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Parkinson Disease
Low Vision Occupational Therapy in Parkinson's Disease
The primary aim of this study is to determine whether low-vision occupational therapy improves quality of life in Parkinson's Disease (PD) patients.
- Trial name
- NCT04127838
- Testing
- Low Vision Occupational Therapy
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Alabama at Birmingham
Glaucoma
Effects of Xal-Ease on Patient Compliance With Xalatan
The study hypothesis is that the Xal-Ease with increase patient compliance with XALATAN
- Trial name
- Xal-Ease (NCT00573638)
- Testing
- Xal-Ease device to be used with Xalatan eye drops
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Augusta University
Myopia
Safety and Effectiveness of CARE1.02 Spectacle Lens in Myopia Control
China is a major country in myopia, with the highest number of teenagers suffering from myopia. Controlling the progression of myopia and the related complications caused by axial elongation have clinical significance and social…
- Trial name
- NCT05818033
- Testing
- CARE1.02, Single-vision spectacle lens
- Where
- China
- Volunteers
- 796 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Glaucoma
A Trial of China Laser and Surgery Study Glaucoma in Rural China
Aims and Objectives (Quantitative) Aim: To compare the effectiveness of selective laser trabeculoplasty with trabeculoplasty in lowering the intraocular pressure in patients with medically uncontrolled open angle glaucoma in…
- Trial name
- NCT02955849
- Testing
- SLT laser
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sun Yat-sen University
Open-angle Glaucoma or Ocular Hypertension
Multi-center Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension
The purpose of this study is to investigate the safety and efficacy of four concentrations of DE-117 ophthalmic solution.
- Trial name
- NCT01868126
- Testing
- DE-117 ophthalmic solution, latanoprost ophthalmic solution
- Where
- 7 sites in United States
- Volunteers
- 91 people
- Sponsor
- Santen Inc.
Inhalational Anesthetics Adverse Reaction, Delirium on Emergence
Effects of Dexmedetomidine Premedication on Emergence Agitation After Strabismus Surgery in Children
Sevoflurane is frequently used for pediatric anesthesia because it has low pungency and rapid onset and offset of action.The reported incidence of emergence agitation (EA) following sevoflurane anesthesia varies from 10-80%.
- Conditions
- Inhalational Anesthetics Adverse Reaction, Delirium on Emergence, Strabismus Following Ocular Surgery
- Trial name
- NCT01895023
- Testing
- Dexmedetomidine, Midazolam, Saline
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Yao Yusheng