Clinical trials: Vision, Low
Amblyopia
Early Detection and Prevention of Amblyopia and Visual Impairment Through Systematic Pediatric Vision Screening
Amblyopia, characterized by reduced visual acuity, develops in childhood due to insufficient sensory stimulation of the affected eye.
- Trial name
- FALSSE (NCT07112560)
- Testing
- Standard screening procedure for amblyopia, New amblyopia screening method using a virtual reality headset.
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Preterm Birth, Visual Impairment
Eye and Growth in Adolescents Born Moderate-to-late Preterm
During recent years, the interest in studying the risks of being born moderate-to-late preterm (MLP), defined as birth between gestational week 32 to 36, has increased.
- Conditions
- Preterm Birth, Visual Impairment, Eye Abnormalities
- Trial name
- NCT04190147
- Testing
- Structural, functional and metabolic eye examinations
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Visual Impairment, Amblyopia
Developing Better Computerised Vision Tests (CVTV)
Clinical vision measurements usually involve printed charts with an eye care professional interpreting patient responses to generate a score. Those scores determine the need for or outcome of treatment.
- Conditions
- Visual Impairment, Amblyopia, Macular Degeneration, Ophthalmic Disease
- Trial name
- CVTV (NCT06224751)
- Testing
- Near logMAR letter acuity, Near LogMAR word acuity, Red Green Stereoacuity
- Where
- United Kingdom
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Near Infrared Spectroscopy
Cerebral Oximetry in Newborns - Comparing INVOS 5100 and FORE-SIGHT Cerebral Oximeters
Regional tissue oxygenation (rStO2) can be monitored by near infrared spectroscopy. The commercial devices FORE-SIGHT (CASMED) and INVOS (COVIDIEN) will be used simultaneously to test for their relative sensitivity for low oxygen…
- Trial name
- NCT01665287
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Breast Cancer Awareness and BSE in Visually Impaired Women
Visually Impaired Women Model-based Cancer Education and Breast Self-examination
The aim of our study was to raise awareness among visually impaired women, who are in the vulnerable group, about breast cancer, which ranks first among female cancers, and to teach breast self-examination.
- Trial name
- NCT06274762
- Testing
- Training and BSE application on a model
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Marmara University
Neurocognitive Disorders, Post Operative Delirium
Safe Brain Initiative, Operationalizing Precision Anaesthesia
Perioperatively, patients experience an unnecessarily high level of side effects associated with their treatment. These side effects include nausea, severe pain, anxiety, and stress.
- Conditions
- Neurocognitive Disorders, Post Operative Delirium, Pain, Nausea
- Trial name
- SBI (NCT05765162)
- Testing
- Patient reported ourcomes
- Where
- Denmark
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Visual Impairment, Age-Related Macular Degeneration (AMD)
Prevalence and Determinants of Shoulder Girdle Musculoskeletal Complaints in Geriatric Patients With Diminished Vision
This case-control study aims to investigate the prevalence and determinants of shoulder girdle musculoskeletal complaints (pain, spasm, stiffness, range of motion impairments) in geriatric patients (aged 60+) with diminished…
- Conditions
- Visual Impairment, Age-Related Macular Degeneration (AMD), Musculoskeletal Pain, Shoulder Pain
- Trial name
- NCT07206654
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Blindness
Evaluation of the Efficacy of the BrainPort Vision Pro on the Performance of Daily Activities in the Profoundly Blind French Population
The purpose of the study is to evaluate the effectiveness and safety of the BrainPort® Vision Pro, an electronic oral assistive device, in the performance of daily tasks by French persons who have residual vision limited to light…
- Trial name
- NCT04725760
- Testing
- BrainPort Vision Pro
- Where
- 7 sites in France
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wicab
Stroke, Ischemic, Hemianopia, Homonymous
Statistical Learning as a Novel Intervention for Cortical Blindness
This project aims to develop a novel visual training paradigm for use in visually-intact participants and those sufferings from stroke-induced visual impairments.
- Conditions
- Stroke, Ischemic, Hemianopia, Homonymous, Hemianopsia, Occipital Lobe Infarct
- Trial name
- NCT06578117
- Testing
- Vision Training and Learning Task
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Normal Tension Glaucoma
Magnetic Resonance Imaging of Patients With Normal Tension Glaucoma
The purpose of this study is to study the occurrence rate of masses such as brain tumors in patients with newly diagnosed Normal Tension Glaucoma.
- Trial name
- NCT00175786
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Low Vision, Macular Edema
Smart-TV Application for the Self Examination of the Distance Visual Acuity in Macular Edema Patients
Primary objective of our study is the development and validation of an application for smart-TVs for the self-examination of the distant visual acuity of patients diagnosed with macular edema.
- Conditions
- Low Vision, Macular Edema, Refractive Errors
- Trial name
- NCT04739137
- Testing
- DDiVAT Testing, Distance visual acuity assessment via ETDRS chart
- Where
- Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Blindness and Low Vision
Blueberry Effects on Dark Vision and Glare Recovery
Clinical evidence for effects of plant anthocyanins on vision, and particularly night vision is controversial. Two clinical trials were conducted to investigate whether blueberry juice consumption affected visual dark adaptation…
- Trial name
- NCT01942746
- Testing
- Blueberry Juice S2, Blueberry Capsules S2, Blueberry Juice L1
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Atlantic Food and Horticulture Research Center
Central Vision Loss From Macular Diseases
Training to Modify Fixational Eye Movements for Optimizing Visual Performance in People With Central Vision Loss
People with central vision loss almost all have exaggerated fixational eye movements when compared with people with normal vision (e.g. larger amplitudes of microsaccades and ocular drifts).
- Trial name
- NCT06670989
- Testing
- Fixation training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Vision Loss
First-Sight Refractive Error Correction in the Developing World
The aim of this study is to test the efficacy of the First-Sight refractive kit designed to provide refractive correction of simple hyperopia, myopia and astigmatism with autorefraction.
- Trial name
- NCT01598818
- Where
- 2 sites in United States, Haiti
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Primary Open Angle Glaucoma, Normal Tension Glaucoma
Advanced Glycation End Products as a Biomarker for Accelerated Ageing
Globally primary open angle glaucoma (POAG) affects over 60 million people. The exact pathogenesis of POAG is poorly understood. A significant risk factor for glaucoma is advancing age.
- Conditions
- Primary Open Angle Glaucoma, Normal Tension Glaucoma, Ocular Hypertension
- Trial name
- NCT02863224
- Where
- United Kingdom
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University of Plymouth
Low Vision Digital Assistance
Development of an ICT Platform-Awareness System for the Support of Low Vision
Low Vision (LV) has a detrimental impact on Quality of Life (QoL) of affected individual's and is considered a major healthcare problem according to World Health Organization.
- Trial name
- LIFE4LV (NCT05184036)
- Testing
- Low Vision
- Where
- Greece
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Sleep Disturbance, Stress
Yoga for Persons With Severe Visual Impairment
This study aims to provide novel information on the feasibility of yoga interventions for secondary symptoms related to severe vision loss, such as sleep disturbances, negative mood states, fall risk and balance.
- Conditions
- Sleep Disturbance, Stress, Anxiety, Depression
- Trial name
- RPY (NCT01366677)
- Testing
- Yoga Intervention
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Vision Disorders
Modification in Cortical Activation in Pseudophakic Patients With Visual Difficulties After a Multifocal Implantation
This study will highlight differences in cortical activation between asymptomatic and symptomatic patients.
- Trial name
- PlainteIMF (NCT02529098)
- Testing
- fMRI
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Visual Impairment, Menstrual Problem
Menstrual Health Education for Visually Impaired Adolescent
This study was planned as a two-group randomized controlled interventional study to determine the effect of face-to-face and web-based menstrual health education given to visually impaired adolescent girls on menstrual attitude…
- Trial name
- NCT06490016
- Testing
- web based education, Face to face
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Children Suffering From Cortical Visual Impairment
Validation of a Parental Questionnaire for Screening Children for Neurovisual Disorders
Some children present visual difficulties linked not to damage to the eye, but to damage to the brain. This type of dysfunction of the visual cerebral pathways leads, for example, to difficulties in recognition, visuomotor…
- Trial name
- NCT06997354
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain