Clinical trials: Veteran
Cisplatin Ototoxicity, Hearing Loss
Randomized Trial Comparison of Ototoxicity Monitoring Programs
This study involves research. Some chemotherapeutic drugs that can permanently reduce hearing are termed "ototoxic". One such drug is the chemotherapy called cisplatin.
- Trial name
- COMP-VA (NCT02099786)
- Testing
- COMP-VA, Standard of care
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stress Disorders, Posttraumatic
Veteran Stress and Learning Study
This is a research study examining the use of two medications, Hydrocortisone and D-Cycloserine, compared to an inactive substance (placebo), on their ability to reduce fear responses and memory of fear in Veterans with symptoms…
- Trial name
- VSL (NCT00674570)
- Testing
- Hydrocortisone, D-Cycloserine
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Attendance at Treatment, PTSD, Substance Use, and Attendance at Treatment
Evaluation and Treatment of Substance Abuse in Veterans With PTSD Disability Claims
Veterans can apply for compensation and pension (C \& P) benefits for a disability related to military service. The application exam for these benefits provides an opportunity for Veterans returning from service to access VA…
- Trial name
- SBIRT-PTSD (NCT01597856)
- Testing
- SBIRT
- Where
- 2 sites in United States
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Electronic Health Records
VA Integrated Medication Manager
The purpose of this study is to advance the science of healthcare informatics and to improve medication management through the development of a new approach to the electronic medical record called the Integrated Medication…
- Trial name
- IMM (NCT01787175)
- Testing
- Integrated Medication Manager
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Utah
Chronic Pain
Treatment, Pain, and Opioids
Background: Chronic pain and negative consequences of long-term opioid therapy are related public health concerns associated with significant functional impairment, high psychiatric comorbidity, and premature mortality…
- Trial name
- NCT05363176
- Testing
- Cognitive-Behavioral Therapy for Treatment Seeking, Pain treatment education
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Post-Traumatic Stress Disorder
Telephone-based Care for OEF/OIF Veterans With PTSD
Objective: OEF/OIF (Operation Enduring Freedom and Operation Iraqi Freedom) veterans are presenting with high rates of PTSD. Translating Initiatives for Depression into Effective Solutions (TIDES) is a model of phone-based care…
- Trial name
- NCT00680524
- Testing
- Phone-based outreach
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Contraception, Contraception Behavior
Patient-Centered Reproductive Decision Support Tool for Women Veterans
The investigators have developed a web-based decision support tool to help women Veterans get the information and care they need to achieve their reproductive goals, whether that includes optimizing their health before desired…
- Conditions
- Contraception, Contraception Behavior, Prepregnancy Health, Reproductive Health
- Trial name
- MyPath (NCT04584294)
- Testing
- MyPath Web-Based Informational and Decision Support Tool
- Where
- 12 sites in United States
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Lung Cancer
Co-Design and Pilot Testing of Peer-led Community Outreach to Improve Equity, Veteran-Centeredness and Uptake of Lung Cancer Screening
Co-design will be implemented to develop an innovative, Veteran-centered intervention (Vet Peer Connects program) that meets the needs of Black Veterans.
- Trial name
- VPC (NCT06389981)
- Testing
- Veterans peer connect Program
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder, Tinnitus
Neurobiological Similarities of Tinnitus and PTSD
Psychiatric distress caused by PTSD may increase attention toward tinnitus, as well as perceived loudness and discomfort. It is important to understand how tinnitus-related distress and PTSD negatively interact together, in order…
- Trial name
- NCT05981391
- Testing
- resting-state functional MRI, Clinician Administered PTSD Scale for the DSM-5 (CAPS-5), Tympanometry
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Insomnia, Alcohol Use Disorder
CBT-I on Alcohol Treatment Outcomes Among Veterans
Project SAVE aims to examine the feasibility, acceptability, and initial efficacy of a CBT-I supplement to alcohol treatment of Veterans.
- Trial name
- Project SAVE (NCT03806491)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene, Alcohol Use Disorder Treatment as Usual
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Postural Balance, Accidental Falls
Improving Balance and Mobility
Falls are dangerous leading to injuries and even death. The VA has made fall prevention a priority, but effective programs only reduce falls by 30%.
- Conditions
- Postural Balance, Accidental Falls, Mobility Limitation
- Trial name
- MMBI (NCT02374463)
- Testing
- MMBI, Tai Chi
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Anger, Aggression
Mindfulness for Anger in Veterans With PTSD
Research has consistently shown that Veterans with PTSD are more likely to experience higher levels of anger and commit aggressive acts compared to Veterans without PTSD.
- Trial name
- NCT02882802
- Testing
- Mindfulness Based Stress Reduction, Trauma Recovery Education Class
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Advance Directives
Enabling Advance Directive Completion
Objectives: The objectives of the pilot study were to (1) test the feasibility of recruitment, randomization, and retention; (2) test the feasibility of a standardized Nurse-Supported Advance Care Planning Intervention; (3)…
- Trial name
- EADCRAV (NCT01746368)
- Testing
- The Nurse-Supported Advance Care Planning Intervention, Care-as-Usual
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Employment
Assessing Supported Employment With Veterans With Felony Convictions and Mental Illness or Substance Abuse
This study continues to develop and refine best practices in the delivery of vocational services to veterans with histories of felony convictions and mental health/substance abuse difficulties.
- Trial name
- NCT01629953
- Testing
- Group vocational intervention, Supported Employment Condition
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Post-traumatic Stress Disorder, Traumatic Brain Injury
Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop
In this proposal, the investigators extend their previous SPiRE feasibility and preliminary effectiveness study to examine STEP-Home efficacy in a RCT design.
- Conditions
- Post-traumatic Stress Disorder, Traumatic Brain Injury, Substance Related Disorders, Depression
- Trial name
- STEP-Home (NCT03868930)
- Testing
- STEP-Home, PCGT
- Where
- 2 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cigarette Smoking
Improving the Delivery of Smoking Cessation Guidelines in Hospitalized Veterans
The primary objective of this study is to determine whether a nurse-initiated intervention, which couples brief inpatient counseling and proactive telephone counseling by a centralized tobacco quitline, improves 6-month cessation…
- Trial name
- NCT00816036
- Testing
- Smoking Cessation Guideline Implementation
- Where
- 4 sites in United States
- Volunteers
- 898 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Mental Health, Suicide
Public Messaging to Increase Treatment Seeking for Veterans at Risk for Suicide
The risk for suicide increases by nearly 50% in the first year that service members transition from the military to civilian life underscoring the need for effective strategies to facilitate help seeking among Veterans vulnerable…
- Trial name
- NCT04784663
- Testing
- Messaging, Wait list control
- Where
- United States
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Dysphagia, Swallowing Disorders
Novel Pharyngeal Metrics to Predict Dysphagia Outcomes
This multi-site trial will follow a cohort of Veterans with dysphagia for 8 weeks as they undergo clinically guided oropharyngeal exercises with oropharyngeal strengthening as the primary goal.
- Trial name
- NCT04569097
- Testing
- standard of care lingual strengthening
- Where
- 3 sites in United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Dementia Family Caregiver Burden and Conflict
Family Telemental Health Intervention for Veterans With Dementia
Dementia impacts Veterans, their families, and other Veterans who serve as caregivers. One of the most stressful aspects of caregiving is the management of behavioral problems (e.g.
- Trial name
- TMH Pilot (NCT03116464)
- Testing
- Telemental Health Family Intervention
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Chronic Pain
Learning to Apply Mindfulness to Pain
The long-term goal of this two-phase project is to reduce chronic pain and co-morbid conditions among Veterans, through scalable, non-pharmacologic evidence-based strategies that are "Veteran-Centric," designed to optimize…
- Trial name
- LAMP (NCT04526158)
- Testing
- Mobile+Group LAMP Mindfulness-Based Intervention, Mobile LAMP Mindfulness-Based Intervention
- Where
- United States
- Volunteers
- 811 people, healthy volunteers welcome
- Sponsor
- United States Department of Defense