Clinical trials: Vestibulodynia
Vulvodynia
Placebo-controlled RCT of Botulinum Toxin A as a Treatment for Provoked Vestibulodynia
Women with provoked vestibulodynia (PVD) suffer from severe dyspareunia and often present a hyperactivity of the pelvic floor muscles (PFM) which maintain the dyspareunia.
- Trial name
- NCT02773641
- Testing
- Botulinum Toxin Type A, Sterile Saline Solution
- Where
- Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Vulvodynia (Chronic Vulvar Pain), Vulvar Vestibulitis
Does a Virtual Program for Pelvic Pain Improve Pain and Sexual Outcomes in Individuals With Provoked Vestibulodynia?
The goal of this clinical trial is to learn if a 3-month online pelvic health program works to improve pain and sexual wellbeing in adult women with chronic genital pain.
- Conditions
- Vulvodynia (Chronic Vulvar Pain), Vulvar Vestibulitis, Vestibulodynia, Provoked Vestibulodynia
- Trial name
- PVD (NCT06999395)
- Testing
- Virtual online pelvic health program
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Queen's University
Vulvodynia, Vulvodynia, Generalized
Effect of Acupuncture on Patient Vulvodynia Outcomes
This study evaluates acupuncture for the treatment of vulvodynia; specifically if it reduces vulvar pain and pain with intercourse. It also examines how long the effect of acupuncture lasts in women with vulvodynia.
- Conditions
- Vulvodynia, Vulvodynia, Generalized, Vulvar Vestibulitis
- Trial name
- NCT03364127
- Testing
- Active Acupuncture
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Illinois Chicago
Genito-Pelvic Pain/Penetration Disorder, Dyspareunia
VIBRating vs Traditional Therapy for Treatment of ENTry Dyspareunia
The goal of this randomized controlled trial is to determine whether the use of a novel vibrating pelvic floor therapeutic device ("Kiwi") improves sexual function in sexually active women aged 18 and older with genito-pelvic…
- Conditions
- Genito-Pelvic Pain/Penetration Disorder, Dyspareunia, Vaginismus, Pelvic Pain
- Trial name
- VIBRENT (NCT06840314)
- Testing
- Pelvic floor therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medstar Health Research Institute
Vulvodynia, Vulvar Vestibulitis
Dysbiosis in Localized Provoked Vulvodynia (LPV)
Currently, the pathogenesis of Localized Provoked Vulvodynia (LPV) has not been elucidated. Few observations may point to involvement of the microbiome: the association of LPV with preceding chronic recurrent candidiasis, and the…
- Trial name
- DMLPV (NCT02393911)
- Testing
- Low Oxalate Diet
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Vulvodynia, Vulvar Vestibulitis
Acupuncture for the Treatment of Vulvodynia
A randomized controlled pilot study was conducted to evaluate the effect of an acupuncture protocol for the treatment of vulvodynia. Hypotheses: 1. Acupuncture reduces vulvar pain and dyspareunia in women with vulvodynia. 2.
- Conditions
- Vulvodynia, Vulvar Vestibulitis, Pain, Dyspareunia
- Trial name
- NCT02197429
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Schlaeger, Judith M., CNM, LAc, PhD
Vestibulodynia, Temporomandibular Disorder
Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments
Vestibulodynia (VBD) is a complex chronic vulvar pain condition that impairs the psychological, physical, and sexual health of 1 in 6 reproductive aged women in the United States.
- Conditions
- Vestibulodynia, Temporomandibular Disorder, Fibromyalgia Syndrome, Irritable Bowel Syndrome
- Trial name
- NCT03844412
- Testing
- 5% lidocaine/5 mg/ml 0.02% estradiol compound cream, Nortriptyline
- Where
- 2 sites in United States
- Volunteers
- 209 people
- Sponsor
- Duke University
Provoked Vestibulodynia, Vulvodynia, Generalized
Internet-based Treatment for Provoked Vestibulodynia
Provoked vestibulodynia is a pain condition, which is associated with lower quality of life and discomfort. Furthermore, it is underdiagnosed and undertreated.
- Trial name
- NCT04045041
- Testing
- Acceptance and commitment therapy
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Uppsala University
Vulvodynia
Efficacy of High Intensity Laser for Provoked Vestibulodynia
This is a multicenter randomized controlled trial (RCT) investigating the effects of laser treatments in women suffering from provoked vestibulodynia compared to a sham-laser treatment.
- Trial name
- Laser_RCT (NCT05597358)
- Testing
- High Intensity Laser Therapy (HILT)
- Where
- 4 sites in Canada
- Volunteers
- 145 people
- Sponsor
- Université de Sherbrooke