Clinical trials: Vertigo
Meniere Disease, Ménière
SPI-1005 for the Treatment of Meniere's Disease
The study is a randomized, double-blind, placebo-controlled, multi-center clinical trial (RCT) with open-label extension study (OLE), of SPI-1005 in adult subjects with definite Meniere's disease with active symptoms within three…
- Trial name
- STOPMD-3 (NCT04677972)
- Testing
- Ebselen
- Where
- 12 sites in United States
- Volunteers
- 220 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Ototoxicity
SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity
The primary objective of this study is to determine the safety and efficacy of SPI-1005 treatment in CF patients with active pulmonary exacerbation that are receiving an IV course of tobramycin, determined by comparing hearing…
- Trial name
- NCT02819856
- Testing
- SPI-1005 Ebselen 200mg Capsule x1, SPI-1005 Ebselen 200mg Capsule x2, SPI-1005 Ebselen 200mg Capsule x3
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Meniere's Disease
Study to Evaluate SPI-1005 in Adults With Meniere's Disease
This study will evaluate the safety and efficacy of three dose levels of SPI-1005 compared to placebo on vertigo, tinnitus and sensorineural hearing loss in 40 adults with Meniere's disease.
- Trial name
- NCT02603081
- Testing
- SPI-1005
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Vertigo, Dizziness
Acute Video-oculography for Vertigo in Emergency Rooms for Rapid Triage (AVERT)
AVERT is a randomized controlled trial comparing video-oculography (VOG)-guided care to standard care to assess accuracy of diagnoses and initial management decisions for emergency department (ED) patients with a chief symptom of…
- Trial name
- AVERT (NCT02483429)
- Testing
- VRT Care
- Where
- 5 sites in United States
- Volunteers
- 130 people
- Sponsor
- Johns Hopkins University
Vertigo, Functional Dizziness
Impact of Vertigoheel® on Patients Suffering From Bilateral Vestibulopathy and Functional Dizziness
In this study the researcher observe how vertigo symptoms change during two months of treatment with the natural medicinal product Vertigoheel©.
- Conditions
- Vertigo, Functional Dizziness, Bilateral Vestibulopathy
- Trial name
- HealVertigo (NCT05897853)
- Where
- Germany
- Volunteers
- 62 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Diabetic Retinopathy, Macular Degeneration
Advancing Understanding of Transportation Options
This Stage II randomized, controlled, longitudinal trial seeks to assess the acceptability, feasibility, and effects of a driving decision aid use among geriatric patients and providers.
- Conditions
- Diabetic Retinopathy, Macular Degeneration, Glaucoma, Retinitis Pigmentosa
- Trial name
- AUTO (NCT04141891)
- Testing
- Driving Decision Aid, Older Drivers Website
- Where
- 3 sites in United States
- Volunteers
- 529 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Dizziness, Vertigo
Trental for the Treatment of Vertigo/Dizziness/Imbalance
Imbalance, dizziness and vertigo as a result of problems in the inner ear (vestibular dysfunction) are becoming increasingly more prevalent in Americans 40 years of age and older.
- Trial name
- NCT02592863
- Testing
- Pentoxifylline
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Missouri-Columbia
Dizziness Chronic, Vertigo, Peripheral
Virtual Environments for Vestibular Rehabilitation
The specific aims of this pilot project are: Aim #1: Determine the extent to which sensory integration strategies differ between 28 individuals with unilateral vestibular hypofunction and 28 age-matched peers.
- Conditions
- Dizziness Chronic, Vertigo, Peripheral, Fall
- Trial name
- NCT04268745
- Testing
- Balance training, Traditional Vestibular Rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- New York University
Meniere's Disease
SPI-1005 for the Treatment of Patients With Meniere's Disease
This study will evaluate the safety, efficacy, and Pharmacokinetics (PK) of two dose levels of SPI-1005 administered for 28 days compared to placebo in patients with Meniere's disease.
- Trial name
- NCT03325790
- Testing
- 200mg SPI-1005 BID, 400mg SPI-1005 BID
- Where
- 13 sites in United States
- Volunteers
- 149 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Dizziness, Vertigo
Sensory Training for Visual Motion Sickness
This is a preliminary study to determine the reliability and validity of new tests of orientation and balance, as well as to test the effects of a new treatment for visually induced dizziness.
- Conditions
- Dizziness, Vertigo, Motion Sickness
- Trial name
- NCT04420949
- Testing
- Sensory re-weighting
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Meniere's Disease
Study of OTO-104 in Subjects With Unilateral Meniere's Disease
The purpose of this study is to evaluate the effectiveness of OTO-104 for the treatment of Meniere's disease.
- Trial name
- AVERTS-2 (NCT02717442)
- Testing
- OTO-104
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Otonomy, Inc.
Meniere's Disease
Study of OTO-104 in Subjects With Unilateral Meniere's Disease
The purpose of this study is to evaluate the effectiveness of OTO-104 for the treatment of Meniere's disease.
- Trial name
- AVERTS-1 (NCT02612337)
- Testing
- OTO-104
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Otonomy, Inc.
Meniere Disease
Phase 3 Study of OTO-104 in Subjects With Unilateral Meniere's Disease
The purpose of this study is to evaluate the effectiveness of OTO-104 for the treatment of Meniere's disease.
- Trial name
- NCT03664674
- Testing
- OTO-104
- Where
- 65 sites in United States, Belgium and 6 more
- Volunteers
- 148 people
- Sponsor
- Otonomy, Inc.
Meniere's Disease, Ménière's Vertigo
Study of Lamotrigine to Treat Ménière's Disease
This double-blinded study evaluates the frequency of vertigo attacks and the quality of life of patients diagnosed with Ménière's disease after being randomly assigned to take a placebo or lamotrigine.
- Conditions
- Meniere's Disease, Ménière's Vertigo, Vertigo, Intermittent, Vertigo, Aural
- Trial name
- NCT02158585
- Testing
- Lamotrigine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Dent Neuroscience Research Center
Vestibular Migraine, Migrainous Vertigo
Rizatriptan for Episodic Dizziness in Vestibular Migraine
Suffering from dizzy spells and migraine headaches? Vestibular Migraine (VM), a newly recognized type of migraine that causes bouts of dizziness.
- Trial name
- NCT02447991
- Testing
- Rizatriptan
- Where
- 3 sites in United States
- Volunteers
- 223 people
- Sponsor
- Robert W. Baloh
Vestibular Migraine
Effects of Lifestyle Modification on Vestibular Migraine
Vestibular migraine was recently addressed by the International Headache Society (IHS) as separate from other types of migraine. Vestibular migraine is one of the most common causes of vertigo attacks, affecting 1-5% of people.
- Trial name
- LMVM (NCT03979677)
- Testing
- Lifestyle Modifications
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Meniere's Disease
Famvir for Treatment of Hearing in Unilateral Meniere's Disease
The specific aim of this study is to determine the efficacy of treatment with famciclovir in unilateral Meniere's Disease patients, specifically whether hearing can be improved.
- Trial name
- Famvir (NCT01526408)
- Testing
- Famciclovir
- Volunteers
- 11 people
- Sponsor
- House Research Institute
Benign Paroxysmal Positional Vertigo
Treating Benign Paroxysmal Positional Vertigo (BPPV) in ED Patients
Benign Paroxysmal Positional Vertigo (BPPV) is a common complaint of emergency department patients. The importance of early diagnosis and treatment can lead to a much improved quality of life for patients afflicted by this…
- Trial name
- NCT00641797
- Testing
- Meclizine, Epley Maneuver, Lorazepam
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Lehigh Valley Hospital
Benign Paroxysmal Positional Vertigo
Treatment of Apogeotropic Horizontal Canal Benign Paroxysmal Positional Vertigo
To determine the short term therapeutic efficacies of Gufoni maneuver and mastoid oscillation in apogeotropic type of benign paroxysmal positional vertigo (BPPV) involving the horizontal semicircular canal (HC-BPPV), a…
- Trial name
- NCT02046980
- Testing
- Gufoni, Vibration
- Where
- South Korea
- Volunteers
- 209 people
- Sponsor
- Keimyung University Dongsan Medical Center
Vertigo
Effectiveness of Betaserc® (Betahistine Dihydrochloride) in Patients With Vestibular Vertigo in Routine Practice
The purposes of this international post-marketing observational program is to investigate effectiveness of betahistine dihydrochloride (Betaserc®) tablets and assess the course of vestibular vertigo after treatment…
- Trial name
- VIRTUOSO (NCT01759251)
- Where
- 24 sites in Russia, Ukraine
- Volunteers
- 309 people
- Sponsor
- Abbott