Clinical trials: Ventricular Function, Left
Embolic Stroke of Undetermined Source, Endothelial Dysfunction
Impaired Endothelial Integrity in Patients With Embolic Stroke of Undetermined Source (ESUS)
The investigators will measure endothelial glycocalyx, aortic elastic properties, oxidative stress, and their association with left ventricular (LV) and left atrial (LA) function in ESUS, cardioembolic, atherosclerotic, lacunar…
- Trial name
- ESUS (NCT03609437)
- Where
- Greece
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University of Athens
Diastolic Function
Determination of Diastolic Dysfunction by Single Lead Electrocardiogram
It is a prospective, controlled, single-center, non-randomized, observational study. From September 2019 to December 2020, the study plans to prospectively include 400 patients aged 18 to 90 years.
- Trial name
- NCT04474639
- Testing
- echocardiographic examination
- Where
- Russia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Prostate Cancer
Effect of Androgen Deprivation Therapy on Cardiovascular Function in Prostate Cancer
The aim of this project is to determine whether androgen deprivation therapy (ADT) decreases left ventricular function in prostate cancer patients.
- Trial name
- NCT03275181
- Testing
- Transthoracic Echocardiography, Arterial blood pressure, Submaximal Exercise
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Left Ventricular Systolic Dysfunction, Healthy Volunteers
Multicenter Normal Reference Study of Tissue Motion Tracking of Mitral Annular Displacement(TMAD)
To establish the range of TMADmid、TMADmidpt% by using tissue motion tracking of mitral annular displacement (TMAD), and to explore the influencing factors.
- Trial name
- TMAD (NCT04399447)
- Testing
- Echocardiography
- Where
- 76 sites in China
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Weidong Ren
Aortic Regurgitation
Diastolic Dysfunction in Aortic Regurgitation
Follow-up study in patients with severe aortic regurgitation after successful valve replacement. Systolic and diastolic function were assessed and persistent diastolic dysfunction was observed late (7-10 years) after operation.
- Trial name
- NCT00976625
- Testing
- Aortic Valve Replacement
- Where
- Switzerland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Bern
Chronic Kidney Disease
Effects of a Reduction in Kidney Function on Cardiovascular Structure and Function: A Prospective Study of Kidney Donors
Studies of patients with established kidney disease, even when this is mild, appear to show that they are at high risk of heart failure, stroke and sudden cardiac death.
- Trial name
- NCT01028703
- Where
- United Kingdom
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Echocardiography, Doppler
Technical Development of Strain Rate Echocardiography
This study will examine heart function using two imaging techniques - echocardiography (ultrasound) and magnetic resonance imaging (MRI) - to evaluate newly developed software for echocardiograph machines.
- Trial name
- NCT00075920
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Ventricular Function, Left
Assessment of Cardiac Involvement of Common Cold in High Performing Athletes by Cardiac Magnetic Resonance Imaging (MRI)
Cardiovascular magnetic resonance (CMR) imaging will be used to assess the impact of common colds and physical training in high-performing athletes. Healthy individuals from the general public will serve as a comparison group.
- Trial name
- NCT00739895
- Testing
- Cardiac magnetic Resonance study, Blood testing
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Chronic Kidney Diseases, Left Ventricular Systolic Dysfunction
Early Evaluation of Left Ventricular Systolic Function Impairment in Patients With Chronic Kidney Disease by Multimodal Ultrasonography
The goal of this observational study is to learn about the value of multimodal ultrasound in early detection of left ventricular systolic dysfunction in patients with chronic kidney disease(CKD).
- Trial name
- NCT06221891
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Cardiac Functional Disturbances During Surgery
A COMPARISON OF LEFT VENTRICULAR FUNCTION IN THE APICAL 4 CHAMBER AND SUBCOSTAL 4 CHAMBER TTE VIEWS IN THE PERIOPERATIVE SETTING
This study aims to examine the correlation and agreement of regional and global measurements of ventricular function in the apical 4 chamber and subcostal 4 chamber view.
- Trial name
- NCT06366061
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eckhard Mauermann
RV - Right Ventricular Abnormality, LV Dysfunction
Pediatric Ventricle Function Assessment Study
This study aims to develop a deep learning-based framework for right ventricular (RV) segmentation, prediction of RV fractional area change (FAC), and identification of pediatric RV dysfunction.
- Conditions
- RV - Right Ventricular Abnormality, LV Dysfunction, Pulmonary Hypertension, TOF
- Trial name
- NCT06739057
- Where
- United States
- Volunteers
- 3,993 people, healthy volunteers welcome
- Sponsor
- HBI Solutions Inc.
Cardiac Function in Young Athletes
Study to Assess the Effect of OXYJUN on Ejection Fraction and Markers of Cardiovascular Injury
Young athletes are usually regarded as a special subgroup of healthy individuals with a unique lifestyle who are apparently invulnerable and often capable of extraordinary physical achievement.
- Trial name
- Enduoxy (NCT02207101)
- Testing
- E-OJ-01 (OXYJUN)
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
EF Evaluation From 4 Chamber Plane, EF Evaluation From 2 Chamber Plane
Automated Left Ventricular Function Evaluation by LVivoEF
Left ventricular ejection fraction (EF) is evaluated in every echocardiographic examination either by visual estimation (eyeballing) requiring high level of training and expertise and/or by manual tracing of the endocard from…
- Conditions
- EF Evaluation From 4 Chamber Plane, EF Evaluation From 2 Chamber Plane, Biplane EF Evaluation, Left Ventricular Function
- Trial name
- LVivoEF (NCT01515267)
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- DiA Imaging Analysis Ltd
Preeclampsia, Severe Preeclampsia
Diastolic Dysfunction 2025
This is a prospective observational study conducted at the Maternity and Neonatology Center of Tunis to evaluate cardiac diastolic function in women with preeclampsia compared with normotensive pregnant women.
- Trial name
- NCT07190846
- Testing
- No Intervention (Observational Echocardiographic Evaluation)
- Where
- Tunisia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Left Ventricular Function Good
Left Atrial Volume and Function in Children Assessed by Echo 3DRT: Reference Values for Normal Children
The investigators study is trying to find the normal value to left atrial volume and left atrial function in healthy children by tridimensional real time echocardiography avaluation.
- Trial name
- NCT01481415
- Where
- 2 sites in Brazil
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Chronic Kidney Diseases, Cardio-Renal Syndrome
Left Ventricular Fibrosis in Chronic Kidney Disease
This study aims to understand the onset an functional consequences of left ventricular interstitial fibrosis in patients with chronic kidney disease (stage 2 to 5), as well as assess whether transplantation results in a…
- Conditions
- Chronic Kidney Diseases, Cardio-Renal Syndrome, Myocardial Fibrosis, Uraemic Cardiomyopathy
- Trial name
- FibroCKD (NCT03176862)
- Testing
- cardiac magnetic resonance scan, Cardiopulmonary exercise test with stress echocardiogram, 24-hour ECG holter monitor
- Where
- United Kingdom
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Dr Manvir Kaur Hayer
Pulmonary Disease, Chronic Obstructive
Effects of Dynamic Hyperinflation on the Left-ventricular Diastolic Function in Healthy Male Subjects
The aim of this study is to identify whether actively induced dynamic hyperinflation can cause left-ventricular diastolic dysfunction in healthy male subjects in order to explore the mechanisms of developing cardiac dysfunctions…
- Trial name
- NCT03500822
- Testing
- Metronome-paced tachypnea, Expiratory-stenosis breathing
- Where
- Austria
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Otto Wagner Hospital
Myocardial Dysfunction
Myocardial Deformation Imaging After Acute Alcohol Excess
Background: Chronic excessive alcohol consumption leads to progressive and chronic cardiac dysfunction. In general, patients consuming alcohol more than five years are at risk for the development of dilated cardiomyopathy.
- Trial name
- C2 (NCT02759445)
- Testing
- routine treatment
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Heart Failure
Evaluation of Systolic Function in Heart Failure With Middle Ejection Fraction by 3D Speckle Tracking Imaging
In 2016, the European Heart Association defined the median ejection fraction heart failure for the first time. More research is needed to improve our understanding of this population, so as to make the best clinical decision and…
- Trial name
- NCT04949997
- Testing
- diagnose
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital