Clinical trials: Ventral Hernias
Ventral Hernia, Incisional Hernia
oPen Versus RobotIc retrOmuscular Repair in Medium to Large Ventral Hernias
This study investigates on the effect of two different operative techniques to treat large abdominal wall defects. The goal of this clinical trial is to learn if the minimally-invasive, robotically-assisted ventral hernia repair…
- Conditions
- Ventral Hernia, Incisional Hernia, Abdominal Wall Defect
- Trial name
- PRIOR (NCT06364306)
- Testing
- Robotically-assisted ventral hernia repair (RVHR), Open ventral hernia repair (OVHR)
- Where
- 3 sites in Germany, Switzerland
- Volunteers
- 140 people
- Sponsor
- University Hospital, Basel, Switzerland
Ventral Hernia
Onlay and Sublay Mesh in Treatment of Ventral Hernia
Hernia is defined as aprotrusion of viscus or part of viscus usually within a peritonial sac through a defect in the abdominal wall.
- Trial name
- NCT06867029
- Testing
- Onlay Mesh
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Pelvic Organ Prolapse, Rectocele
Multicenter Ventral Mesh Rectopexy Registry Collaborative
The goal of this multicenter observational study is to collect data prospectively of patients with pelvic organ prolapse undergoing ventral mesh rectopexy (as well as rectoceles, entero-/sigmoidoceles/ intussusception/ rectal…
- Conditions
- Pelvic Organ Prolapse, Rectocele, Enterocele, Rectal Prolapse
- Trial name
- M2R2 (NCT05918367)
- Where
- 5 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Antwerp
Hernia
Biological Mesh Repair of Complex Hernias in High Risk Patients
Complex ventral hernia repair is a significant surgical challenge with high frequencies of both wound complications and recurrence.
- Trial name
- NCT01997619
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Umbilical Hernia
Mesh Versus Suture Repair for Umbilical Hernias
The purpose of the present study is to investigate whether or not the use of mesh is indicated in the repair of all size umbilical hernias as to reduce the rate of recurrence.
- Trial name
- HUMP (NCT00789230)
- Testing
- primary suture closure, mesh enforced closure
- Where
- 12 sites in Germany, Italy and 1 more
- Volunteers
- 300 people
- Sponsor
- Ruth Kaufmann, MD
Ventral Hernia
Post Market Study of Parietene™ DS Composite Mesh in Ventral Hernia Repair
A multi-center post-market single arm prospective study of Parietene™ DS Composite Mesh in subjects undergoing ventral hernia repair to confirm its clinical safety and performance in the short (1, 3 months), mid (12 months) and…
- Trial name
- PPDS (NCT03495154)
- Testing
- Parietene DS Composite Mesh
- Where
- 6 sites in United States
- Volunteers
- 145 people
- Sponsor
- Medtronic - MITG
Hernia, Ventral, Hernias Intestinal
Optimization of Surgical Treatment of Patients With Incisional Ventral Hernias
The goal of our work of optimization of the treatment of postoperative hernias is to improve the results of treatment of patients with median and median-lateral postoperative hernias of medium (W2) and large (W3) sizes by…
- Conditions
- Hernia, Ventral, Hernias Intestinal, Hernia Abdominal Wall
- Trial name
- NCT05734222
- Testing
- A new method of repair of the abdominal wall of mid-lateral postoperative ventral hernias
- Where
- Russia
- Volunteers
- 110 people
- Sponsor
- Samara State Medical University
Ventral Hernia, Abdominal Wall Defect
Intraoperative Biomechanics in Complex Abdominal Wall Reconstruction
Background: A detailed study of the biomechanical changes before and after abdominal wall reconstruction (AWR) has not been performed.
- Trial name
- NCT03296475
- Testing
- Abdominal Wall Closure Force (N).
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University College, London
Open Midline Laparotomy
Prophylactic Reinforcement of Ventral Abdominal Incisions Trial
This trial is being conducted to evaluate the efficacy of Phasix™ Mesh implantation at the time of midline fascial closure compared to primary suture closure in preventing a subsequent incisional hernia in subjects at risk for…
- Trial name
- PREVENT (NCT03911700)
- Testing
- Phasix™ Mesh
- Where
- 32 sites in United States, Austria and 3 more
- Volunteers
- 477 people
- Sponsor
- C. R. Bard
Primary Ventral and Incisional Hernia Repair
Progrip Ventral Study for Sublay Repair
A novel concept of self-gripping mesh has been developed to achieve secure and long-term posterior wall reinforcement. ProGrip™ mesh is a lightweight (40g/m2) monofilament polypropylene or polyester mesh with resorbable…
- Trial name
- NCT01622127
- Testing
- Parietex ProGrip™
- Where
- Belgium
- Volunteers
- 55 people
- Sponsor
- University Hospital, Ghent
Pain, Postoperative, Anesthesia, Local
Improving Pain Relief Following Laparoscopic Ventral Hernia Repair
Aim The general aim of this study is to improve post-operative pain and reduce morphine consumption following laparoscopic ventral hernia repair (LVHR).
- Conditions
- Pain, Postoperative, Anesthesia, Local, Hernia, Ventral, Laparoscopy
- Trial name
- NCT02785276
- Testing
- AutoFuser Pain Pump, Ropivacaine, Normal Saline (0.9%)
- Where
- New Zealand
- Sponsor
- University of Auckland, New Zealand
Ventral Hernia, Ventral Hernia Repair
Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis Release
This study is comparing two ways to manage pain after a major hernia repair surgery called "transversus abdominis release." One method uses an epidural, a small tube placed in the back that delivers pain medicine directly around…
- Conditions
- Ventral Hernia, Ventral Hernia Repair, Postoperative Pain
- Trial name
- EASE-TAR (NCT07840183)
- Testing
- Bupivicaine, Fentanyl, Thoracic epidural analgesia
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwestern University
Umbilical Hernia, Cholelithiasis
Prevalence of Cholelithiasis with Umbilical Hernia
Researchers aim to determine the exact prevalence and risk factors for the association of gallstones and umbilical hernia. Umbilical hernia is defined according to the European Hernia Society Classification for primary and…
- Trial name
- NCT06522308
- Testing
- Hepatobiliary ultrasound, Umbilical region superficial tissue ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 278 people
- Sponsor
- Konya Meram State Hospital
Ventral Incisional Hernia
Only Mesh Fixation With Glue of Ventral/Incisional Laparoscopic Hernia Repair
This multicenter randomized controlled non-inferiority trial of only mesh fixation with a glue applicator is a trial to evaluate the outcomes between atraumatic laparoscopic mesh fixation with GLUTACK-Glubran2® and conventional…
- Trial name
- OMEGA (NCT06183840)
- Testing
- Glutack, Conventional
- Volunteers
- 250 people
- Sponsor
- Institut Catala de Salut
Ventral Hernia
Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair
A ventral hernia happens when the muscles in the front of your belly become weak and let organs push through, causing a bulge. If it gets worse, intestines can slip into the bulge, leading to serious pain and health problems.
- Trial name
- NCT07226791
- Testing
- AGN-151607-DP
- Where
- 13 sites in United States
- Volunteers
- 200 people
- Sponsor
- AbbVie
Hernia, Hernia, Ventral
T-GENVIH-003 LTFU (Long Term Follow Up) Study
The T-GENVIH-003 study will collect additional, longer term performance data of Gentrix® Surgical Matrix used for reinforcement of ventral hernia repairs from a subset population (i.e., the twenty-one minimally invasive surgical…
- Conditions
- Hernia, Hernia, Ventral, Pathological Conditions, Anatomical, Hernia, Abdominal
- Trial name
- NCT06034652
- Testing
- Integra® Gentrix® Surgical Matrix
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Integra LifeSciences Corporation
Ventral Hernia Repair
Biosynthetic Absorbable Mesh vs Standard of Repair for the Surgical Treatment of Infected Incisional Hernia
Incisional hernia is one of the most common complications of abdominal surgery and carries a significant burden for both patients and the economic health service.
- Trial name
- COMpACT-BIO (NCT04597840)
- Testing
- Incisional hernia repair with reinforcement of biosynthetic mesh, Incisional hernia repair with simple suture or synthetic mesh reinforcement.
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Hospices Civils de Lyon
Ventral Hernia
Laparoscopic Versus Robot-assisted Ventral Hernia Repair: a Single Institution Randomized Controlled Trial
Randomized trial to compare outcomes of robot-assisted and laparoscopic ventral hernia repair surgery.
- Trial name
- NCT03133715
- Testing
- laparoscopic repair, robot-assisted repair
- Where
- United States
- Sponsor
- University of Florida
Hernia, Recurrence
Magnetic Resonance Imaging of Mesh Position After Ventral Hernia Repair
Purpose of the study is the visualization of the mesh and the determination of the mesh surface observed by MRI at 3 weeks and 13 months after ventral hernia repair with mesh visible IPOM (Dynamesh®).
- Trial name
- NCT02177214
- Testing
- MRI scan
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Umbilical Hernia, Ventral Hernia
Natural Orifice Translumenal Endoscopic Surgery (NOTES): Laparoscopic Assisted Transvaginal Ventral Hernia Repair
This is a prospective chart review/data collection study of natural orifice translumenal endoscopic surgery (NOTES) for ventral hernia repair, that will include questionnaires administered throughout the study.
- Trial name
- NOTES (NCT01398215)
- Testing
- transvaginal NOTES ventral hernia repair
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego