Clinical trials: Venous Malformations, open to volunteers
Arteriovenous Malformation, Gastrointestinal Bleed
Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable Coils
The purpose of the Case-Specific Health Care Professional (HCP) Clinical Survey for Concerto Versa™ Detachable Coils, also known as the Concerto Versa HCP Clinical Assessment, is to collect early clinical data from HCPs to assess…
- Conditions
- Arteriovenous Malformation, Gastrointestinal Bleed, Gastric Varices, Hemorrhoid
- Trial name
- NCT07639853
- Testing
- Concerto Versa™ Detachable Coils
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Medtronic Endovascular
Venous Malformations, Lymphatic Malformations
A Study to Investigate Efficacy and Safety of KP-001 Compared With Placebo in Patients Aged ≥2 Years With Common VM, Common LM, or KTS/CLOVES Syndrome
This is a phase 3, double-blind, randomized, placebo-controlled, parallel group, adaptive, multicenter study planned to be conducted at multiple sites in North America, Canada, Taiwan and South Korea.
- Conditions
- Venous Malformations, Lymphatic Malformations, Klippel-Trenaunay Syndrome, CLOVES Syndrome
- Trial name
- S-KY (NCT07285005)
- Testing
- KP-001
- Where
- 5 sites in United States, South Korea and 1 more
- Volunteers
- 150 people
- Sponsor
- Kaken Pharmaceutical
Venous Malformation, Low Flow, Venous Malformations
Acetylsalicylic Acid Versus Placebo as an add-on Treatment to Local Non-steroidal Anti-inflammatory Drug for the Management of Thrombotic Episodes in Superficial Venous Malformations in Children Aged 6 to 17 Years.
Superficial venous malformations (SVMs) are rare congenital anomalies that present as bluish masses. These masses may be focal, with limited skin involvement, or segmental, with more extensive involvement.
- Trial name
- ASPIRIN (NCT07663825)
- Testing
- AAS at anti-inflammatory doses from 3 days to 14 days., Application of Diclofenac gel 1% twice a day
- Where
- 6 sites in France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Tours
Slow-Flow Vascular Malformation, Fast-Flow Vascular Malformation
A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations
Recent studies have demonstrated that growth of vascular malformations can be driven by genetic variants in one of 2 signalling pathways.
- Conditions
- Slow-Flow Vascular Malformation, Fast-Flow Vascular Malformation, Vascular Malformations, Venous Malformation
- Trial name
- TARGET-VM (NCT05983159)
- Testing
- Alpelisib, Mirdametinib
- Where
- 2 sites in Australia
- Volunteers
- 50 people
- Sponsor
- Murdoch Childrens Research Institute
Arterio-venous Fistula, Intracranial Arteriovenous Malformations
PHIL® Embolic System Pediatric IDE
The purpose of this study is to collect information about how the PHIL® Embolic System works in the treatment of intracranial dural arteriovenous fistulas.
- Trial name
- NCT03731000
- Testing
- PHIL® device
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Alejandro Berenstein
Vascular Malformations, Arteriovenous Malformations
A Study to Evaluate the Efficacy and Safety of Everolimus in Patients With Teratment-refractory Vascular Anomalies
Background and Objectives Vascular anomalies are a heterogeneous group of disorders classified into vascular tumors and vascular malformations according to the ISSVA classification.
- Conditions
- Vascular Malformations, Arteriovenous Malformations, Venous Malformation, Lymphangioma
- Trial name
- NCT07477548
- Testing
- Everolimus
- Volunteers
- 67 people
- Sponsor
- Yonsei University
Venous Malformation, Lymphatic Malformation
Weekly Sirolimus Therapy
In current practice, options for venous and lymphatic malformations remain limited. Recently an oral medication, sirolimus, has been found to benefit patients when taken once or twice a day for several months.
- Trial name
- NCT04861064
- Testing
- Sirolimus
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Medical University of South Carolina
Venous Malformations, Arteriovenous Malformations
Microwave Ablation for Treatment of Vascular Malformations: Efficacy and Safety
This clinical trial aims to assess the safety and efficacy of microwave ablation in treating vascular malformations, including both venous malformations (VM) and arteriovenous malformations (AVM).
- Conditions
- Venous Malformations, Arteriovenous Malformations, Microwave Ablation, Vascular Malformations
- Trial name
- NCT07404670
- Testing
- Microwave Ablation
- Volunteers
- 150 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Venous Malformation
Efficacy and Safety Analysis of Polylauric Alcohol More Stable Foam Versus Ordinary Foam in the Treatment of Head and Neck Venous Malformations
The aim of this study is to explore the efficacy and safety of poly -LRB-cinnamyl alcohol) foam in the treatment of venous malformations of head and neck through a prospective randomized clinical trial, this trial may provide…
- Trial name
- NCT07066527
- Testing
- The addition of sodium hyaluronate to poly (cinnamyl alcohol-RRB- produces a more stable foam
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Vascular Malformation, Arteriovenous Malformation
Diagnostic Imaging of Vascular Malformations Using MSOT and ULM
This clinical study evaluates the efficacy and accuracy of Multispectral Optoacoustic Tomography (MSOT) and Ultrasound Localization Microscopy (ULM) for imaging and diagnosing vascular malformations (venous, arteriovenous…
- Conditions
- Vascular Malformation, Arteriovenous Malformation, Lymphatic Malformation, Venous Malformations
- Trial name
- NCT06994260
- Testing
- Multispectral Optoacoustic Tomography, Ultrasound Localization Microscopy
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- University Hospital Erlangen
Venous Malformation, Pain
A Study of Enalapril in Treatment of Venous Malformations
The goal of this clinical trial is to explore if enalapril can be used to treat painful venous malformations. The main question it aims to answer are: Can enalapril reduce pain and volume of the malformation and increase quality…
- Conditions
- Venous Malformation, Pain, Quality of Life, Vascular Malformation
- Trial name
- EVA (NCT06788314)
- Testing
- Enalapril
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Oslo University Hospital
Venous Malformation, Low Flow, Anticoagulants
A Study of Direct Oral Anticoagulants in Patients with Painful Venous Malformations with Localized Intravascular Coagulation
There are two parts of the study. In Part 1, the invesitgaotrs want to investigate whether treatment with apixaban improves pain and quality of life in patients with painful venous malformations The participants are randomized to…
- Trial name
- AVA (NCT06729034)
- Testing
- Apixaban (Eliquis)
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital