Clinical trials: Venous Insufficiency
Nocturia, Venous Insufficiency of Leg
Discovering the Effect of Venous Insufficiency on Nocturia
With this prospective controlled trial, we hope to obtain more information about the coexistence between venous insufficiency and nocturia.
- Conditions
- Nocturia, Venous Insufficiency of Leg, Fluid Overload
- Trial name
- DEVINe (NCT04266496)
- Testing
- Questionnaires, Frequency Volume Chart, Collect urine during 1 day
- Where
- Belgium
- Volunteers
- 84 people
- Sponsor
- University Hospital, Ghent
Venous Ulcer
Clinical Effectiveness of Topical Autologous Platelet Gel for the Treatment of Venous Ulcers
The purpose of this study is to compare the effectiveness of standard venous ulcer care to standard venous ulcer care plus a cell based product made from the patients own blood.
- Trial name
- NCT00273234
- Testing
- Autologous Platelet Gel (APG)
- Where
- 6 sites in United States
- Volunteers
- 70 people
- Sponsor
- National Healing Corporation
Catheter Thrombosis, Post Thrombotic Syndrome
Incidence and Characteristic of CRT Persistent After Catheter Extraction in ICU Patients
The goal of this observational study is to describe characteristics of catheter related thrombosis (CRT) that persists after catheter extraction in condition of intensive care unit. The main questions it aims to answer are: 1.
- Conditions
- Catheter Thrombosis, Post Thrombotic Syndrome, Pulmonary Embolism (Diagnosis)
- Trial name
- CRT-PERSIST (NCT07473284)
- Testing
- No Interventions
- Volunteers
- 300 people
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Chronic Venous Insufficiency
Manual Lymphatic Drainage in Chronic Venous Insufficiency: a Randomized Controlled Trial
The purpose of this study is to compare functional status and quality of life of a group of patients with chronic venous insufficiency treated with manual lymphatic drainage with a group not treated with manual lymphatic…
- Trial name
- MLDCVI (NCT01899482)
- Testing
- Manual Lymphatic Drainage, Education
- Where
- Portugal
- Volunteers
- 41 people
- Sponsor
- Technical University of Lisbon
Chronic Venous Insufficiency
Study to Evaluate Impact SANKOM Patent Socks in Patients With CVI
Clinical study to evaluate impact on quality of life in patients with Chronic Venous Insufficiency during 4 weeks period of using SANKOM® Patent Socks
- Trial name
- NCT03445091
- Testing
- SANKOM Patent Socks
- Where
- 2 sites in Ukraine
- Volunteers
- 30 people
- Sponsor
- Sankom SA
Great Saphenous Vein Incompetence, Visible Varicosities
Endovenous Ablation With and Without Polidocanol Endovenous Microfoam Treatment for Patients With Great Saphenous Vein Incompetence and Visible Varicosities
Varicose veins are enlarged, noticeably bulging veins, which commonly occur in the legs and may cause discomfort. In this study, patients with varicose veins in the legs will be participating.
- Trial name
- 017 (NCT01197833)
- Testing
- endovenous ablation+polidocanol injectable microfoam 0.125%, Endovenous ablation+polidocanol injectable microfoam 1.0%, Endovenous ablation+polidocanol injectable foam 2.0%
- Where
- 7 sites in United States
- Volunteers
- 117 people
- Sponsor
- Boston Scientific Corporation
Lower Extremity Edema, Lower Extremity Edema Chronic
Pedal Pump Clinical Trial on Edema V2
Previous research on the osteopathic manual technique entitled "Pedal Pump" has shown health benefits, specifically increasing lymphatic flow, decreasing lower extremity edema, and decreasing serum lactic acid after maximal…
- Conditions
- Lower Extremity Edema, Lower Extremity Edema Chronic, CHF - Congestive Heart Failure, CHF Exacerbation
- Trial name
- NCT07809516
- Testing
- Pedal Pump
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hillcrest
ARDS, Acute Kidney Injury
Mechanical Ventilation-induced Acute Kidney Injury [AKI]
Positive end-expiratory pressure (PEEP) is a fundamental tool in the management of patients with acute respiratory distress syndrome (ARDS). However, there is currently no common criterion for deciding which level of PEEP to use.
- Trial name
- AKI (NCT06638255)
- Testing
- Sequence A involves administering Low PEEP for 12 hours, followed by High PEEP for 12 hours., Sequence B involves setting High PEEP for 12 hours, followed by Low PEEP for 12 hours.
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Pontificia Universidad Catolica de Chile
ECMO, Heparin
Veno-venous Extracorporeal Membrane Oxygenation (VV-ECMO) Heparin Study
This single-center, open-label study will evaluate the safety and efficacy of subcutaneous heparin anticoagulation compared to the standard of care systemic intravenous anticoagulation during veno-venous extracorporeal membrane…
- Conditions
- ECMO, Heparin, Respiratory Failure
- Trial name
- NCT04496362
- Testing
- subcutaneous heparin anticoagulation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor Research Institute
Venous Insufficiency of Leg
SOCKNLEG Compression Stocking Kit : User Friendliness
The investigators aim to evaluate the user friendliness of a newly designed leg compression stocking kit, the SOCKNLEG, compared to a standard leg compression stocking of the same compression strength, the SIGVARIS Cotton.
- Trial name
- SOCKNLEGZH (NCT03429959)
- Testing
- SOCKNLEG, SIGVARIS Cotton
- Where
- Switzerland
- Volunteers
- 47 people
- Sponsor
- University of Zurich
Chronic Venous Insufficiency
Study to Assess the Efficacy and Safety of Endolex Forte VErsus Diosmin and Hesperidin in Reducing VeNous Insufficiency
The trial is designed as a randomized, multicenter, open label, comparative, 6 months, clinical study.
- Trial name
- EVELINE (NCT02927483)
- Testing
- Endolex Forte®, A combination of diosmin and hesperidin
- Volunteers
- 120 people
- Sponsor
- SunWave Pharma
Prostate Cancer
Perioperative Changes of Cognitive Function According to Jugular Vein Insufficiency in Robot-assisted Prostatectomy
Internal jugular vein (IJV) is the main pathway of cerebral venous drainage and it has valve system to prevent retrograde blood flow to the brain.
- Trial name
- NCT01905488
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Venous Leg Ulcer, Venous Ulcer
Tissue Repair Gel in Venous Leg Ulcers in AU/US
The goal of this clinical trial is to learn if TR987 0.1% gel + Standard of Care works better than Standard of Care alone to treat Venous Leg Ulcers (VLUs).
- Conditions
- Venous Leg Ulcer, Venous Ulcer, Venous Stasis Ulcer, Venous Stasis
- Trial name
- TRIVIA (NCT06707103)
- Testing
- TR987 0.1% gel + Standard of Care, Standard of care
- Where
- 12 sites in United States, Australia
- Volunteers
- 312 people
- Sponsor
- TR Therapeutics
Kidney Failure, Acute, Critical Illness
Comparison of Femoral Versus Jugular Routes for Temporary Hemodialysis in Seriously Ill Patients
The purpose of this study is to determine whether a jugular route leads to a lower rate of complications as compared with a femoral route for catheterization in patients admitted in several intensive care units in France who…
- Trial name
- CATHEDIA (NCT00277888)
- Testing
- Femoral route for hemodialysis, Jugular route for hemodialysis
- Where
- 10 sites in France
- Volunteers
- 750 people
- Sponsor
- University Hospital, Caen
Venous Thromboembolism
Fondaparinux in Critically Ill Patients With Renal Failure
The primary objective of this study is to determine whether a dose-adjusted prophylaxis fondaparinux regimen of 2.5 milligrams (mg) subcutaneously administered every (q) 48 hours (hr) in patients with renal failure achieves peak…
- Trial name
- NCT01467583
- Testing
- Fondaparinux
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Wayne State University
Chronic Venous Insufficiency
Venous Pressure Measurement of the Great Saphenous Vein Using Controlled Compression Ultrasound in Healthy Persons and Patients With Chronic Venous Disease as a New Non Invasive Method for Investigation of the Pathophysiology in Primary Varicose Veins
Part I: Proof of concept trial to achieve normal venous pressure values under different provocation maneuvers in healthy persons Part II: Non invasive measurement of venous pressure under different provocation maneuvers in…
- Trial name
- NCT01000909
- Testing
- Ultrasound (venous pressure measurement)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Zurich
Venous Insufficiency
Physical Conditioning in Management of Chronic Venous Insufficiency
The purpose of this research is to evaluate the efficacy of a structured program of physical therapy in ameliorating the adverse consequences of Chronic Venous Insufficiency (CVI).
- Trial name
- NCT00013273
- Testing
- Physical Conditioning
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- US Department of Veterans Affairs
Venous Thromboembolism, Renal Impairment
Enoxaparin 20mg Versus 30mg Subcutaneously Once Daily in Elderly Patients With Impaired Renal Function
This is a clinical trial including non-surgical patients, 70 years of age or older, with renal impairment requiring pharmacological venous thromboembolism prevention during hospitalization.
- Trial name
- NCT03158792
- Testing
- Enoxaparin 20Mg/0.2mL Prefilled Syringe, Enoxaparin 60Mg/0.6Ml Inj Syringe 0.6Ml
- Where
- Lebanon
- Volunteers
- 32 people
- Sponsor
- Lebanese American University
Chronic Venous Insufficiency, Chronic Venous Thrombosis
Best Endovenous Treatment, Including STenting, Versus Non-endovenous Treatment in Chronic Proximal Deep Venous Disease
Chronic obstruction of the iliac veins or inferior vena cava can occur as a result of deep vein thrombosis (DVT), or due to extrinsic compression in non-thrombotic iliac vein lesions (NIVLs).
- Conditions
- Chronic Venous Insufficiency, Chronic Venous Thrombosis, Iliac Vein Stenosis, Iliac Vein Obstruction
- Trial name
- BEST (NCT05622500)
- Testing
- Deep venous stenting, Best medical therapy
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Imperial College London
Varicose Veins of Lower Limb, Hemorrhoids
HEMOVAR Study on Hemorrhoids and Varicose Veins
The HEMOVAR Study is a prospective observational study designed to evaluate the association between hemorrhoidal disease and lower extremity varicose veins.
- Trial name
- HEMOVAR (NCT07317492)
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Aydin Adnan Menderes University