Clinical trials: Vascular Surgery
Neuro-co-cardiological Diseases, Post-cardiac Surgery Cerebrovascular Diseases
Outcomes and Risk Factors of Different Treatment Strategies for Neuro-co-cardiological Diseases and Post-cardiac Surgery Cerebrovascular Diseases
The objective of this observational cohort study is to evaluate the clinical outcomes of various treatment strategies for cerebrovascular and cardiovascular diseases.
- Conditions
- Neuro-co-cardiological Diseases, Post-cardiac Surgery Cerebrovascular Diseases, Vascular Lesion
- Trial name
- NCT07012668
- Testing
- Interventional or surgical treatment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Anzhen Hospital
Peripheral Arterial Disease, Venous Thormboembolism
VTE Incidence After Rivaroxaban + Aspirin or SAPT After Lower-limb Revascularization
Venous thromboembolism (VTE) has a high prevalence in patients with multiple comorbidities undergoing complex surgical procedures.
- Conditions
- Peripheral Arterial Disease, Venous Thormboembolism, Cardiovascular Diseases, Vascular Surgery Patient with PAD / Carotid Stenosis
- Trial name
- RESOLUTION (NCT06873321)
- Testing
- rivaroxaban 2.5 mg bid + aspirin 100 mg, clopidogrel 75 mg od for 3 months followed by aspirin 100 mg od for endovascular procedures or aspirin for open procedures
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Science Valley Research Institute
Heart Surgery, Vascular Surgery
Anticoagulation and Inflammation Monitoring in Patients After Heart and Vascular Interventions
The goal of this prospective observational study is to evaluate the most appropriate anticoagulation monitoring tool for unfractionated heparin (UFH), by comparison of different monitoring modalities in relation to adverse events…
- Conditions
- Heart Surgery, Vascular Surgery, Delirium, Hyperinflammatory Syndrome
- Trial name
- PAC-AIM (NCT06222866)
- Testing
- Anticoagulation monitoring
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Medical University Innsbruck
Surgery (Cardiac), Surgery (Major Vascular)
The SMArTVIEW, CoVeRed
The SMArTVIEW program evaluates the use of remote, automated monitoring in hospital and at home, on patients undergoing cardiac and major vascular surgery, to determine the effect on the 45-day risk of a composite of hospital…
- Trial name
- SMArTVIEW (NCT03253549)
- Testing
- SMArTVIEW
- Where
- 2 sites in Canada, United Kingdom
- Volunteers
- 572 people
- Sponsor
- McMaster University
Non-Cardiac/ Non-Thoracic Surgery, Abdominal Surgery
Assisted Fluid Management IDE Study
The primary objective of this study is to evaluate the performance of the Acumen™ Assisted Fluid Management (AFM) Feature in its ability to predict a subject's fluid responsiveness.
- Conditions
- Non-Cardiac/ Non-Thoracic Surgery, Abdominal Surgery, Pelvic Surgery, Major Peripheral Vascular Surgery
- Trial name
- AFM (NCT03469570)
- Testing
- EV1000 Clinical Platform with Assisted Fluid Management (AFM) Feature
- Where
- 10 sites in United States
- Volunteers
- 330 people
- Sponsor
- Edwards Lifesciences
Vascular Diseases, Surgery
Monocentric Retrospective Observational Study; Analysis of Gore Excluder ACS Device Using Numerical Simulation
andated when the risk of rupture is low and interventional treatment is offered to patients at high risk of rupture. Rupture risk is driven by aneurysm diameter and growth rate.
- Trial name
- ACSSim (NCT06428877)
- Testing
- analyzed on the post-operative scanner
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Vascular Diseases, Patient Empowerment
PREMs In Vascular SurgERy Enhancement Study
THE PROBLEM: Patient Reported Experience Measures (PREMs) ask patients about their healthcare service experience. It gives them a voice to share their views.
- Conditions
- Vascular Diseases, Patient Empowerment, Patient Satisfaction, Patient Engagement
- Trial name
- PREMIERE (NCT06363175)
- Where
- United Kingdom
- Volunteers
- 330 people
- Sponsor
- Cardiff and Vale University Health Board
Vascular Diseases, Peripheral Artery Disease
The ALOFT Pilot Trial
The ALOFT Pilot Trial will evaluate three pragmatic elements (recruitment, adherence, and follow-up) of neuraxial versus general anesthesia for lower limb revascularization surgery that are necessary to support a successful…
- Conditions
- Vascular Diseases, Peripheral Artery Disease, Surgery
- Trial name
- NCT06067789
- Testing
- neuraxial anesthesia
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Ottawa Hospital Research Institute
Frailty, Anesthesia
Complexity and Frailty in Cardiothoracic and Vascular Anesthesia (CAfCA). Prospective Multicentric Observational Study
Frailty is a multidimensional syndrome characterized by a decline in physiological homeostatic reserve, which translates into an increased susceptibility to adverse events and unfavorable outcomes following even small exposures…
- Conditions
- Frailty, Anesthesia, Thoracic Surgery, Cardiothoracic Surgery
- Trial name
- CAfCA (NCT05968456)
- Testing
- Data collection
- Where
- 8 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Istituto Clinico Humanitas
Vascular Surgery
POWER: PrehabilitatiOn Workshop and Mentored Exercise Programme in Patients Having Elective Aortic Aneurysm Repair
Protocol Short Title: POWER Study - PrehabilitatiOn Workshop and mentored Exercise programme in patients having elective aortic aneurysm Repair Population: Patients scheduled for elective repair of aortic aneurysm at St.
- Trial name
- POWER (NCT04169217)
- Testing
- Prehabilitation
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Type 2 Diabetes, Lifestyle
Nursing Prehabilitation Intervention Supported With Technology for Vascular Surgery in People With Type 2 Diabetes
Type 2 Diabetes Mellitus (T2DM) is the most common chronic lifestyle-related disorder with a significant impact on quality and healthcare expenditures.
- Conditions
- Type 2 Diabetes, Lifestyle, Prehabilitation, Vascular Surgery
- Trial name
- VITAAAL (NCT06248775)
- Testing
- Prehabilitation Intervention Supported with Technology (Fitbit, glucose sensor and app for diet habits)
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Nicole Oosterom
Myelodysplastic Syndromes, Acute Myeloid Leukemia
Constitution of a Biological Cohort Following Bone Marrow Sampling From MDS or AML Patients and Age-matched Healthy Donors
It is of clinical significance to better characterize the intrinsic defects harbored by mesenchymal stromal cells (MSC) in Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) context, as compared to physiological…
- Conditions
- Myelodysplastic Syndromes, Acute Myeloid Leukemia, Cardio-vascular Surgery
- Trial name
- COSMOS (NCT03233074)
- Testing
- Bone marrow analyses
- Where
- 2 sites in France
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Spinal Anesthesia, Vascular Surgery
Hyperbaric Novabupi® in Spinal Anesthesia in Lower Limbs Vascular Surgery
This is a multicenter, randomized, double-blind, active-controlled study to evaluate the non-inferiority of hyperbaric Novabupi® versus hyperbaric Neocaine® in spinal anesthesia in lower limbs vascular surgery.
- Trial name
- NCT03883763
- Testing
- bupivacaine S75:R25 plus 8% glucose, bupivacaine S50:R50 plus 8% glucose
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Cristália Produtos Químicos Farmacêuticos Ltda.
Abdominal Vascular Surgery, Peripheral Vascular Surgery
A Retrospective, Observational, Multicenter, Study to Collect Clinical Safety and Performance Data on POLYMAILLE®C
Purpose of the study is to describe safety and performance of POLYMAILLE® C from a minimum of 200 subjects will be evaluated. A minimum of 100 subjects will be evaluated for each main location of surgery (abdominal and…
- Conditions
- Abdominal Vascular Surgery, Peripheral Vascular Surgery, Vascular Prothesis, Aneurysm Abdominal
- Trial name
- NCT05517876
- Testing
- Vascular abdominal or peripheral surgery
- Where
- France
- Volunteers
- 212 people
- Sponsor
- Perouse Medical
Surgery, Vascular Diseases
NMES for Rehab After Surgery
A randomised pilot study assessing the acceptability and feasibility of utilising neuromuscular stimulation devices to enhance post-operative rehabilitation and recovery after general, vascular and urological surgery procedures.
- Trial name
- NCT04784962
- Testing
- Revitive Medic Neuromuscular Stimulation Device
- Where
- United Kingdom
- Volunteers
- 103 people
- Sponsor
- Imperial College London
Nociceptive Pain, Goal-directed Therapy
Nol-Index Guided Remifentanil Analgesia Versus Standard Analgesia During Moderate-to-High Risk Cardiovascular Surgery
This study will investigate the potential of guiding remifentanil analgesia during cardiac and vascular surgery in moderate to high risk patients requiring general anesthesia.
- Conditions
- Nociceptive Pain, Goal-directed Therapy, Hemodynamic Instability, Nol-Index
- Trial name
- NCT04137991
- Testing
- Nol-Index guided analgesia, Standard Analgesia
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Erasme University Hospital
Vascular Surgery, Ischemia-reperfusion
Effects of Ischemic Preconditioning After Aortic Clamping
Open surgery for aneurysmal aortic disease can lead to cardiac, renal, pulmonary or muscular complications, essentially due to the aortic clamping. Ischemic preconditioning can be useful in order to decrease these complications.
- Conditions
- Vascular Surgery, Ischemia-reperfusion, Ischemia Preconditioning
- Trial name
- NCT02254642
- Testing
- Ischemic preconditioning during aortic clamping, Procedure/Surgery: usual surgery
- Where
- 4 sites in France
- Volunteers
- 59 people
- Sponsor
- University Hospital, Strasbourg, France
Drug Effect, Children, Only
The Efficacy and Safety of Different Phlebotonic Drugs in Children With Venous Malformations
The aim of this study is to evaluate the efficacy and safety of different phlebotonic drugs in children and to assess patient satisfaction after treatment.
- Conditions
- Drug Effect, Children, Only, Vascular Malformations, Surgery
- Trial name
- NCT05113420
- Testing
- Detralex, Troxevasin
- Where
- Russia
- Volunteers
- 1,000 people
- Sponsor
- Center for Vascular Pathology, Moscow
Cardiac Surgery, Vascular Surgery Using CPB
Impact of Retrograde Autologous Priming on the Coagulation Profile Assessed by Rotation Thromboelastometry (ROTEM) in Patients Undergoing Cardiac Surgery
Cardiac surgery with cardiopulmonary bypass (CPB) is associated with an increased risk of blood transfusions. The primary setup of the CPB circuit demands a priming volume of approximately 1600 mL of crystalloid solution which…
- Trial name
- NCT04239677
- Testing
- Conventional crystalloid solution-based priming, Retrograde autologous priming
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Yonsei University
Vascular Reconstruction in Pelvic Exenterative Surgery
The Role of Vascular Reconstruction in the Setting of Pelvic Exenteration
Local invasion or abutment of a major vascular structure was once a major deterrent to planned oncological resection. Improvements in radiological assessment and vascular surgical techniques have enabled resection of major blood…
- Trial name
- NCT04948879
- Testing
- Vascular resection/reconstruction
- Volunteers
- 100 people
- Sponsor
- St Vincent's University Hospital, Ireland